Go to the main menu
Skip to content
Go to bottom
REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
The Journal of Oriental Obstetrics and Gynecology
Journal Basic Information
Journal DOI :
The Society of Korean Medicine Obstetrics and Gynecology
Editor in Chief :
Volume & Issues
Volume 22, Issue 4 - Nov 2009
Volume 22, Issue 3 - Aug 2009
Volume 22, Issue 2 - May 2009
Volume 22, Issue 1 - Feb 2009
Selecting the target year
The Effect of Mibaeksan(MB) on Melanin Synthesis and Gene Expression
Kim, Soo-Min ; Yoo, Dong-Youl ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 1~18
Purpose: This study was performed to elucidate the inhibitory effect of Mibaeksan (MB) on melanin synthesis in B16F10 mouse melanoma cell. Methods: To demonstrate the inhibitory effects of MB on melanin synthesis, we measured the amount of released and produced melanin in B16F10 melanoma cell. Also, we evaluated tyrosinase-activity in vitro as well as in B16F10 melanoma cell. And to investigate the action mechanism, we assessed the gene expression of tyrosinase, TRP-1, TRP-2, MMP-2, PKA,
, ERK-1 ERK-2, AKT-1 and MITF in B16F10 melanoma cells. Results: 1. MB decreased the release and production of melanin in B16F10 melanoma cells. 2. MB decreased tyrosinase activity in vitro and in B16F10 melanoma cells. 3. MB decreased the expression of tyrosinase, TRP-1, TRP-2, PKA,
and MMP-2 in B16F10 melanoma cells. 4. MB increased the expression of ERK-1, ERK-2 and AKT-1 in B16F10 melanoma cells. 5. MB decreased the expression of MITF in B16F10 melanoma cells. Conclusion: From these results, it may be concluded that MB has the antimelanogenetic effects.
Acute Toxicity Study on Fermented Ojeok-san(Wuji-san) Extract in Mice
Um, Young-Ran ; Lee, Jae-Hoon ; Lee, Ji-Hye ; Moon, Hyun-Jung ; Park, Hwa-Yong ; Cho, Chang-Won ; Ma, Jin-Yeul ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 19~27
Purpose: This study was carried out to investigate the acute toxicity and safety of fermented Ojeok-san(Wuji-san) extract. Methods: To evaluate the acute toxity and safety, 0(control group), 1250, 2500 and 5000 mg/kg of fermented Ojeok-san(Wuji-san) extract were orally administered to 20 male and 20 female ICR mice. After single administration, we observed survival rates, general toxicity, changes of body weight, and autopsy. Results: Compared with the control group, we could not find any toxic alteration in all treated groups (1250, 2500 and 5000 mg/kg). Conclusions:
of fermented Ojeok-san(Wuji-san) extract might be over 5000 mg/kg and it is very safe to ICR mice.
The Effect of Yukmijihwangtanghapyijihwangagambang on Melanin Synthesis and Related Gene Expressions in B16F10 Mouse Melanoma Cell
Shin, Sun-Mi ; Yoo, Dong-Youl ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 28~45
Purpose: This study was performed to elucidate the inhibitory effect of Yukmijihwangtanghapyijihwangagambang (YM) on melanin synthesis in B16F10 melanoma cells. Methods: To demonstrate the inhibitory effects of YM on melanin synthesis, we measured the amount of released and produced melanin in B16F10 melanoma call. Also, we evaluated tyrosinase-activity in vitro as well as in B16F10 melanoma call. And to investigate the action mechanism, we assessed the gene expression of tyrosinase, TRP-1, TRP-2, PKA,
, ERK-1 ERK-2, AKT-1 and MITF in B16F10 melanoma call. Results: 1. YM decreased the release and production of melanin in B16F10 melanoma cells. 2. YM decreased tyrosinase activity in vitro and in B16F10 melanoma cells. 3. YM decreased the expression of tyrosinase, TRP-1, TRP-2 in B16F10 melanoma cells. 4. YM decreased the expression of PKA,
in B16F10 melanoma cells. 5. YM increased the expression of ERK-1, ERK-2 and AKT-1 in B16F10 melanoma cells. 6. YM decreased the expression of MITF in B16F10 melanoma cells. Conclusion: From these results, it may be concluded that YM has antimelanogenetic effects.
The Literatual Study of Kamisoyo-san on Menopausal Disorder
Lee, Se-Na ; Leem, Kang-Hyun ; Ju, Young-Seung ; Son, Jae-Bong ; Kim, Hyung-Jun ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 46~64
Purpose: The purpose of this study is to discuss the usage of Kamisoyo-san on menopausal disorder by literatual research. Methods: 33 papers and 47 books about Kamisoyo-san and menopausal disorder were used to develop this article. Results: According to the papers and the books, Soyo-san was first appeared in Taepyungheminhwajegookbang. It was modified to Kamisoyo-san and it has been used to treat menopausal disorder for more than several hundreds of years. There is much evidence of the causes, mechanisms, and symptoms of menopausal disorder corresponding with Kamisoyo-san's indications. Currently, scientific research supports that Kamisoyo-san has many effects on the symptoms of menopausal disorder. Conclusions: Kamisoyo-san is effective on menopausal disorder. We suggest that Kamisoyo-san should be given an insurance code for the treatment of menopausal disorder for the benefits to numerous patients suffering from the disorder.
Investigation of Clinical Research of Acupuncture Intervention in Assisted Reproductive Technology in Pubmed
Bae, Geung-Mee ; Cho, Hye-Sook ; Lee, Seung-Hwan ; Lee, In-Sun ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 65~82
Purpose: The purpose of this study is to examine acupuncture intervention suggested in the papers of assisted reproductive technology(ART, hereafter) in medicine journals and to establish the further direction. Methods: The papers published between 1996 and 2009 in Pubmed were reviewed. Results: 1. A variety of randomized controlled trials and case series were found in Pubmed concerning influence of acupuncture in ART. It was investigated into improvement of pregnancy rate, analgesic effect during oocyte retrieval, change of serum hormone, and reduction of anxiety. 2. It was on clinical pregnancy rate that main focus of the investigation was placed and the improvement of pregnancy rate differed from studies. 3. For the analgesic effect during oocyte retrieval, the electro acupuncture was mainly used and the studies reported the reduced pain rate, tiredness, and nausea. 4. Acupuncture was reported as significant in improving the state of anxiety during ART. Conclusion: It would be necessary to further study the period of acupuncture intervention, the selection of acupoint through well-designed study, and establish standard of evidence of them.
Systemic Review on Complementary and Alternative Medicine for Endometriosis
Kwon, Ji-Myung ; Park, Young-Sun ; Kim, Dong-Chul ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 83~92
Purpose: The aim of this study was to review systemically journals on the studies for complementary and alternative medicine in the treatment of endometriosis. Methods: Through medical websites, foreign clinical literatures about complementary and alternative medicines of endometriosis were searched. The cite used was http://www.Pubmed.gov. And then they were divided into three groups. In vitro, in vivo, clinical studies. Results: 1. We researched 2 papers about in vitro. Both were used extract of herbal mixture. And they used CCL5, SE-1, COUP-TF, 17-
-HSD2 which were not commonly used in Korea. 2. We researched 8 papers about in vivo. Most of them used blood-activating stasis-dispelling medicine, just few used tonic medicine. And they used acupuncture which were not used in Korea. Most of Korean paper also used blood-activating stasis-dispelling medicine and rarely used tonic medicine. 3. We researched 19 papers about clinical studies. They had much more cases(average=60) than Korean paper. They were also used western medicine randomized sham-controlled trial. Conclusion: Afterward we need to study for comparing western medicine and herb medicine. And we concern about acupuncture therapy.
A Study on Characters of DITI, HRV and Body Composition Analysis in Amenorrhea
Jeong, Jae-Hyuk ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Cho, Jung-Hoon ; Jang, Jun-Bock ; Lee, Kyung-Sub ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 93~100
Purpose: The purpose of this study is investigate the characters of DITI, HRV and Body composition analysis in Amenorrhea. Methods: We studied 47 patients visiting ○○ hospital from 1st October 2007 to 19st September 2009. The subjects were categorized in two groups, amenorrhea group(26) and normal group(21). We studied the difference of DITI, HRV and Body composition analysis between two groups by Mann-whitney test using SPSS for windows(version 12.0). Results: there is not statistically significant difference of DITI, HRV and BMI between amenorrhea group and normal group. But there is statistically significant difference of percent body fat and waist-hip ratio between amenorrhea group and normal group. Conclusion: Percent body fat and Waist-Hip ratio of amenorrhea groups is lower than normal groups. Percent body fat and Waist-Hip ratio can be diagnosis index.
Multicorrelation Study on the Change of Menstrual Cycle Affected by Stress and Obesity
Jang, Hee-Jae ; Moon, Seung-Joon ; Yoon, Young-Jin ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Cho, Jung-Hoon ; Jang, Jun-Bock ; Lee, Kyung-Sub ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 101~108
Purpose: Integrative studies have been made to review the correlationship of menstrual period with obesity and stress, and the relationship between stress and obesity has been reconfirmed through the study. Methods: Among the first time outpatients who visited the gynecological department of the OO oriental medical center from May 1st to September 1st of the year 2009, total 114 patients were included for the study by excluding the patients who received uterine hysterectomy, patients taking hormonal medications, and the patients who installed intrauterine devices. Survey has been made to investigate patients' age, menstrual period and duration of menstrual period. The investigation for the degree of obesity and stress was conducted as in below. Results: 1. From the menstrual cycle difference reviewed by Gonadosomatic index (GSI), the severe GSI group tended to show longer menstrual cycle than moderative GSI group. 2. From the menstrual cycle difference reviewed by Body Mass Index (BMI), longer menstrual cycle was observed from the abnormal BMI group than the normal BMI group. 3. No correlative probability values of GSI and BMI were observed. 4. Although the linear regression analysis result of BMI and GSI with the menstrual cycle did not show any statistical significance, the study resulted to show a tendency. Conclusion: Although the correlationship of menstrual cycle with obesity and stress did not show any significance, it is considered that the menstrual period could be affected by the combination of the variables rather than by independent variable.
A Study on the Severity of Dysmenorrhea according to Digestive Power, BMI in the High School Female
Yang, Na-Rae ; Cho, Jung-Hoon ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Jang, Jun-Bock ; Lee, Kyung-Sub ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 109~121
Purpose: The purpose of this study was to find out the correlation among body mass index (BMI), dysmenorrhea and digestion function. Methods: We conducted a questionnaire survey of 307 high school girls about their menstruation and digestion function from one high school located in Seoul from Mar. 23 to Mar. 28 in 2009. And the we measured their height and weight to calculate their BMI. Using one way ANOVA, chi-square test and pearson correlation, statistical analysis was made by SPSS 12.0. We significance level p-value was determined as 0.05. Results: 1. There was no significant correlation between BMI and the severity of dysmenorrhea. 2. There was no significant correlation between BMI and digestion power. 3. There was statistically mild correlation between dyspepsia and the severity of menstrual pains. Conclusion: From above results, we could conclude that dyspepsia had mild relation to menstrual pains.
A Study on Blood Stasis Pattern for 159 Hysterectomy Patients
Choi, Jin-Young ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Cho, Jung-Hoon ; Jang, Jun-Bock ; Lee, Kyung-Sub ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 122~134
Purpose: The purpose of this study is to know the blood stasis pattern for the patients who had hysterectomy. Methods: Among the patients who had hysterectomy in the department of obstetrics and gynecology, OO medical center from March 3rd 2009 to October 21st 2009, subjects who met inclusion criteria and submitted appropriate questionnaire. We compared blood stasis score and operational method, age, BMI, past operation history of abdominal and pelvic site, parity, whether adhesiolysis, oriental medicine intervention was done. For statistics, we used independent samples t-test, oneway analysis of variances(ANOVA) and SPSS version 13.0 for windows. Results: Blood stasis score of the subtotal hysterectomy group (
) is higher than that of the total hysterectomy group(
). Blood stasis score under the age 40(
) is higher than 40-49 age patients(
) and over the age 50 patients(
). There is no statistically significant difference between laparoscopic and abdominal trial, whether adhesiolysis, oriental medicine intervention was done, BMI, past operation history abdominal and pelvic site, parity, chief complaint before hysterectomy, oriental medicine intervention. Conclusion: Through the results showed, when traditional Korean medical doctors use static blood medication, history of hysterectomy and age should be considered as the history of subtotal hysterectomy and younger age tend to have a higher rate of a blood stasis pattern. We need a further study to develop blood stasis indicators with a validated questionnaire, and more subjects involved at multiple institutions.
A Study on Correlation between Stress and Menstruation among Low-income Women
Kim, Hyun-Jung ; Kim, Yoon-Sang ; Lim, Eun-Mee ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 135~148
Purpose: The purpose of this study is to recognize correlation between stress and menstrual pattern among low-income women. Methods: From 5th October to 24th October 2009 we researched 14 low-income mothers by questionnaires to investigate their stress and menstrual patterns. Results: The mean level of their stress was
. The less the income was, the higher the stress was. Among the women, the stress of those who do not had husbands was also high. Most of the women's menarche came late and their menstrual cycle was long. The menstrual color was a little dark and they had blood clots and pain during menstruation. Their mental states also often changed over the period and they had pattern of blood stasis. The study observed that the higher the stress was, the worse the menstrual pain was. Conclusion: Low-income women are under stress by their socioeconomic status and their menstrual patterns often change. Stress has correlation with menstruation.
Association of Sasang Constitution with Bone Mineral Density in Postmenopausal Korean Women
Kim, Eun-Sook ; Cho, Jung-Hoon ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Jang, Jun-Bock ; Lee, Kyung-Sub ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 149~156
Purpose: To evaluate the association of sasang constitution with bone mineral density (BMD) in postmenopausal Korean women. Methods: Sasang constitution was analyzed by Phonetic System for Sasang Constitution in 92 postmenopausal Korean. The BMD was checked using dual-energy x-ray absorptiometer(DEXA) at lumbar spine, femur neck. Results: Bone mineral density of lumbar spine(T-score) according to Sasang constitution was Taeumin(
). Bone mineral density of femur neck(T-score) according to Sasang constitution was Taeumin(
). Conclusion: There was significant relationship between sasang constitution and BMD of femur neck. There was no significant relationship between sasang constitution and BMD of lumbar spine.
A Survey on Post Gynecology Surgery Patient in Oriental-Western Cooperative Medicine
Lee, Seung-Hwan ; Lee, In-Sun ; Cho, Hye-Sook ; Bae, Geung-Mee ; Kim, Chul ; Park, Sung-Hwan ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 157~172
Purpose: The purpose of this study is to analyze the status of cooperative treatment of western-oriental medicine in post gynecological surgery. Methods: This study is conducted by investigating the hospitalized patient's medical chart and OCS dated from March 2008 to May 2009 in obstetrics and gynecology of oriental medicine department in Dong-Eui medical center. The total patient number was 58. Results: Out of 58 women, 74.1% complained abdominal pain and discomfort, 24.1% complained headache and dizziness, 22.4% complained lumbago, 22.4% complained lethargy and fatigue. There were 63.8% women in the age group between 41 to 50 and 20.7% women in the age group between 31 to 40. 53.4% women hospitalized for less than 7 days, 43.1% women hospitalized for 8 to 14 days. 53.4% had uterine myoma, 20.7% had more than two types of complex diseases and 19.0% had adenomyosis uterine. 60.3% had total hysterectomy and 27.6% had simple hysterectomy. 64.9% had abdominal surgery, 17.5% had laparoscope surgery and 15.8% had hysteroscope surgery. 62.8% of 43 women complained abdominal pain and discomfort, 78.6% of 14 women complained headache and dizziness, 46.2% of 13 women complained lumbago, 84.6% of 13 women complained lethargy and fatigue improved to VAS 0-3. Conclusion: The results has shown that it is necessary to have cooperative treatment of both western-oriental medicine for the effective treatment in managing post gynecological surgery. The further study in data collection and manual development is needed.
A Study about the Satisfaction of Oriental Medical Postpartum Care
Bak, Ji-Young ; Park, Jung-Kyung ; Park, Ka-Young ; Kim, Tae-Hee ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 173~186
Purpose: 1. To analyze the satisfaction and cognition of postpartum care and to aid the spread of oriental medicine in postpartum care. 2. Get a basic guideline of O.M.D's postpartum care. Methods: We studied the satisfaction and cognition of postpartum care with questionnaire from January 2009 to August 2009, who was treated in ○○ Oriental Medical Postpartum care center during 2 weeks. 61 puerperants answered us. Results: 1. In choosing Postpartum care center, puerperants concerned about new born infants' care(50.8%) and treatment for discomfort after delivery(27.86%). 2. 22 puerperants(36.6%) had a positive view in folk remedy for postpartum care and 34 puerperants(55.73%) thought it would be good to eliminate edema and loose weight. 3. Most of puerperants(80.32%) chose oriental medical postpartum care because they wanted to receive oriental medical treatment. 4. 5 puerperants(8.19%) were very satisfied with oriental medical postpartum care than other type of postparum care which they experienced at first delivery. 47(77.04%) were satisfied, 2(3.27%) were unsatisfied and no one was very satisfied. 5. To the questionnaire about the effect of strength recovery, lochia excretion, edema limination, increasing amount of breastmilk, reducing arthralgia, about 36.8% puerperants showed positive view. 6. The positive view about Acupuncture, cupping, moxibustion, herbal treatment was, respectively, 90.16%, 49.18%, 73.77%, 86.88%. Conclusion: Puerperants were satisfied with oriental medical postpartum care and had positive cognition in oriental medical treatment. There is much capability for extension of oriental medicine in postpartum care. So continuous concern, systemic development and publicity about oriental medical postpartum care are required.
A Case of Suggested Behcet's Disease Patient Treated by Gamchosasim-tang
Yang, Dong-Seon ; Gu, Hee-Jun ; Yeo, Eun-Ju ; Yang, Seung-Jung ; Jo, Sung-Hee ; Park, Kyung-Mi ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 187~193
Purpose: This paper is aim to report the effects of Gamchosasim-tang(GCT) on the genital ulcer suggested Behcet's disease. Methods: The patient in this case was 45-year-old. The chief complains were genital ulcers, mouth ulcers, fatigue, skin lesions (hand site), eye discomfort. She was treated by GCT. The progress of symptoms were evaluated by visual analogue sclae. Results: After the treatments, genital ulcer pain and mouth ulcer pain disappeared, fatigue, skin lesions, eye discomfort decreased. Conclusion: This clinical case indicate that GCT is effective in treatment of the genital ulcers. And GCT is considered that good effect is to Behcet's disease.
Case Series of Low Back Pain and Pelvic Pain Caused by Traffic Accident during Pregnancy
O, Kwang-Woo ; Ryu, Ik-Han ; Kim, Ji-Ryang ; Kim, Hae-Jung ; Kang, Jung-Ah ; Lee, Su-Jeong ; Choi, Chang-Min ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 194~204
Purpose: When pregnant women get symptom like pain, because of fear of using analgesic drugs and X-ray test during pregnancy, pain is nevertheless often left. This study was to report the clinical application and safety of oriental treatment to low back pain and pelvic pain caused by traffic accident during pregnancy. Methods: We experienced seven patients who suffered from low back pain and pelvic pain caused by traffic accident during pregnancy. During their admission, we treated with acupuncture, cupping therapy and herbal medicine. We checked the symptoms during admission at progress note, and follow up by phone call. Results: The degree of low back pain and pelvic pain were decreased or resolved. After treatment, no serious adverse effects were found on the patients, and there were no adverse effects at all on the infants. Conclusion: The results indicate that oriental treatment can be effective for the management of low back pain and pelvic pain caused by traffic accident during pregnancy. And these treatments are safe to both patients and infants.
A Case Report of One Patient with Adenomyosis
Yu, Sung-Jin ; Yoon, Moon-Hee ; Kim, Hyung-Jun ; Lee, Dong-Nyung ;
The Journal of Oriental Obstetrics and Gynecology, volume 22, issue 4, 2009, Pages 205~214
Purpose: Adenomyosis is the disease caused by ingrowth of lining tissue into the uterine muscle. Final treatment of the disease is hysterectomy but there is a tendency to avoid surgical treatment if possible. And medication often results in relapse and it does not cure completely. This paper introduces the potential of oriental medical treatment for adenomyosis through a case study. Methods: A 31-year-old female patient, suffered from pelvic pain and metrorrhagia, was diagnosed with adenomyosis and uterine myoma. She was put on oriental medical treatment in the ○○ Oriental Hospital for almost three months. We applied herb-medication, acupuncture and moxibustion. Results: Overall condition including the symptoms was relieved after oriental medical treatment Conclusion: Oriental medical treatment alleviates chronic pelvic pain and has an effect against adenomyosis.