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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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The Journal of Oriental Obstetrics and Gynecology
Journal Basic Information
Journal DOI :
The Society of Korean Medicine Obstetrics and Gynecology
Editor in Chief :
Volume & Issues
Volume 26, Issue 4 - Nov 2013
Volume 26, Issue 3 - Aug 2013
Volume 26, Issue 2 - May 2013
Volume 26, Issue 1 - Feb 2013
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Effects of Dokhwalgisaengtang-gami Water Extract on Osteoclast Differentiation and Osteoblast Function in RANKL-induced RAW 264.7 Cell
Je, Yun-Mo ; Yoo, Dong-Youl ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 1~16
DOI : 10.15204/jkobgy.2013.26.2.001
Objectives: This study was performed to evaluate the effect of Dokhwalgisaengtang-gami water extract(DGG) on osteoporosis. Methods: The osteoclastogenesis and gene expression were determined in RANKL-stimulated RAW 264.7 cell. And osteoblastogenesis was also determined in rat calvarial cell. Results: The results were summarized as followes. 1. DGG decreased the number of TRAP positive cell in RANKL-stimulated RAW 264.7 cell. 2. DGG inhibited TRAP activity in RANKL-stimulated RAW 264.7 cell. 3. DGG decreased the expression of NAFTc1, MITF in RANKL-stimulated RAW 264.7 cell. 4. DGG increased the expression of iNOS, COX-2, IL-6 in RANKL-stimulated RAW 264.7 cell. 5. DGG decreased the expression of cathepsin K, MMP-9, TRAP in RANKL-stimulated RAW 264.7 cell. 6. DGG increased cell proliferation of rat calvarial cell. 7. DGG increased ALP activity in rat calvarial cell 8. DGG increased bone matrix protein, collagen synthesis and nodule formation in rat calvarial cell. Conclusions: It is concluded that DGG might decrease the bone resorption resulted from decrease of osteoclast differentiation and it's related gene expression. And DGG might increase the bone formation resulted from increase of osteoblast function.
A Study on the Inhibitory Effect and Mechanism of Lonicera Japonica on Type I Interferon
Kang, Yong-Goo ; Ryu, Ik-Han ; Kim, Song-Baek ; Choi, Chang-Min ; Seo, Yun-Jung ; Cho, Han-Baek ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 17~32
DOI : 10.15204/jkobgy.2013.26.2.017
Objectives: The purpose of this study was to investigate whether Lonicera japonica(LJ) could inhibit LPS-induced type I IFN production. Methods: To evaluate inhibitory effect of LJ on type I IFN, we examined type I IFN, IRF-1, 7 and IL-10 production on LPS-induced macrophages using real time RT-PCR. Next, we observed the interaction of type I IFN, IRF-1, 7 and IL-10 using IL-10 neutralizing antibody. Finally we examined the activation of STAT-1, 3 using western blot. Results: LJ inhibited Type I IFN expression of mRNA and increased IL-10 expression of mRNA. Also LJ inhibited the level of IRF-1, 7 mRNA and the nuclear translocation of IRF-3. Further more, LJ reduced the activation of STAT-1, 3 which are involved in continuous secretion of immune cytokines. Blockade of IL-10 action caused a significant reduction of type I IFN and IRF-1, 7 than LPS-induced LJ pretreatment. Conclusions: LJ inhibits LPS-induced production of type I IFN by IL-10. This study may provide a clinical basis for anti-inflammatory properties of LJ.
Changes of Depression and Fatigue Level According to Sasang Constitution in Early Postpartum Women
Lee, Ah-Young ; Park, Ga-Young ; Lee, Eun-Hee ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 33~45
DOI : 10.15204/jkobgy.2013.26.2.033
Objectives: The purpose of this study was to identify the tendency toward depression and fatigue in early postpartum women and to determine the relationship between the symptoms of these conditions, according to the women's Sasang constitutions. Methods: In this study, 73 healthy postpartum women were analyzed according to Sasang constitution: 33 Taeeumin, 22 Soyangin, and 18 Soeumin. Symptoms of depression and fatigue were assessed using the Edinburgh Postnatal Depression Scale-K(EPDS-K) and the Fatigue Continuum Form(FCF), respectively, on the fourth(time 1), seventh(time 2), and fifteenth(time 3) days postpartum. Sasang constitutional types were determined by a medical specialist, using results from the Two Step Questionnaire for Sasang Constitution Diagnosis(TS-QSCD). Results: 1. The overall depressive symptoms and fatigue scores decreased significantly over time in early postpartum women. 2. The mean scores for the EPDS and FCF were higher in the Soeumin group than in other groups. The scores for EPDS and FCF dropped sharply in comparison to a former level in the Soyangin group. And the mean EPDS score was lower in the Soyangin group than in other groups. The EPDS and FCF scores in the Taeeumin group changed slightly over time. However, these results were not statistically significant according to Sasang constitution. 3. The relationship between postpartum depression and fatigue showed a significant positive correlation. Conclusions: These results suggest that, in early postpartum women, depressive symptoms and fatigue differ according to Sasang constitution.
A Study of the Thoroughfare and Conception Vessels' Emaciation through Epidemiologic Research about Menstrual Disorders of Female High School Students in Busan
Kang, Yu-Jeong ; Choi, Yu-Jeong ; Lee, In-Seon ; Cho, Hye-Sook ; Ji, Gyue-Yong ; Lee, Yong-Tae ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 46~65
DOI : 10.15204/jkobgy.2013.26.2.046
Purpose: Generally menstrual disorder caused by functional deficiency of ovary is not treated clinically because it manifests as normal process of growth. In this study we collected experimental group having several or severe menstrual disorder and we tried to find out whether there is any relationship between menstrual disorders and the function of Thoroughfare and Conception vessels or not. Methods: First, this study was researched to learn the meaning and the symptoms of 'the emaciation of Thoroughfare and Conception vessels', and to learn the relationship between menstrual disorders and 'the emaciation of Thoroughfare and Conception vessels' through literature review. And we set up a experimental group who have two or more menstrual disorders or severe degree of menstrual disorders(N=97) and control group who don't have menstrual disorders(N=97) as a result of the menstruation survey. Afterwards we conducted the DSOM in both experimental group and control group. Results and Conclusions: The meaning of 'the emaciation of Thoroughfare and Conception vessels' is deficiency of qi and blood from the Thoroughfare and Conception vessels. As a result, the female reproductive system is difficult to be worked properly with deficiency of skin, muscles, bone, and vessels. Symptoms of the emaciation of Thoroughfare and Conception vessels are classified into drying, skinny body, feeling of cold, menstrual disorders, pain and personality traits. In this study, severity of drying, skinny body, feeling of cold, menstrual disorders, pain and personality traits is significantly higher in experimental group than in control group. Like this, symptoms of 'the emaciation of Thoroughfare and Conception vessels' appear with menstrual disorders because disorder of circulation is occurred by qi and blood deficiency of Thoroughfare and Conception vessels. It is appropriate to identify this case as 'the emaciation of Thoroughfare and Conception vessels' pattern and necessary to treat actively through regulating qi and blood in advance.
Systematic Review on Complementary and Alternative Medicine for Female Sexual Dysfunction
Jeong, Young-Min ; Kim, Song-Baek ; Choi, Chang-Min ; Seo, Yun-Jung ; Cho, Han-Baek ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 66~87
DOI : 10.15204/jkobgy.2013.26.2.066
Objectives: The aim of this study was to review systemically clinical trials on the trends of studies for Complementary and Alternative Medicine in the treatment of female sexual dysfunction and provide basic resource for future treatment and suggestions for improving research methods. Methods: Through medical website 'Pubmed', foreign clinical literatures about female sexual dysfunction were searched and domestic clinical literatures about female sexual dysfunction were searched using internet websites 'National assembly library', 'KISS', 'RISS', 'Korean traditional knowledge portal'. Results: Total 19 literatures were selected from January 2000 to June 2012. 15 foreign literatures were selected through medical website and 4 domestic literatures were chosen using internet websites or hand-searching. 5 literatures were published in 2008 and 13 literatures mentioned about age group of patients. FSFI is most common tool for female sexual dysfunction. 9 of 19 literatures were using Herbal medicine for treatment. 5 literatures were about CBT, 6 literatures were about Biofeedback and other one literatures are about Perineal massage. There were 14 Randomized controlled trials and 5 Non-randomized controlled trials. And randomized controlled trials were relatively low in risk of bias than non-randomized controlled trials. Conclusions: Upon these results, in similar future more clinical trials should be done and accumulate Evidence-based literatures.
A Study on the Change of Digital Infrared Thermographic Imaging and Skin Resistance Variability before and after Treatment of Dysmenorrhea
Kim, Hyeon-Ju ; Lee, Yong-Hyun ; Sohn, Young-Joo ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 88~103
DOI : 10.15204/jkobgy.2013.26.2.088
Purpose: The aim of this study was to examine the effect of oriental diagnosis and treatment for dysmenorrhea patients on lower abdominal temperature and Skin Resistance Variability(SRV). Methods: We studied twenty-five dysmenorrhea patients, who visited Oriental Medicine Hospital of
University for 10 months(Sep. 2011~Jun. 2012). Patients with organic disease such as endometriosis, uterine myoma and pelvic inflammatory disease were excluded from this study. We prescribed 3 types of treatments, herbal medicine, acupuncture, and moxibustion, for one menstrual cycle. Digital Infrared Thermographic Imaging(DITI), 7-Zone-Diagnostic System(CP-6000A), VAS(Visual analog scale) and MVRS(Multidimensional verbal rating scale) were conducted before and after the treatment. The result of DITI, 7-Zone-Diagnostic System, VAS and MVRS before and after treatment were compared in order to objectively assess the therapeutic effect. Results: When we compared the results of DITI, CV4 temperature after treatment was increased compared with that of before, and temperature difference between CV12 and CV4 after treatment was decreased compared with that of before. But there was no significant difference. When we compared the results of 7-Zone-Diagnostic System at 1st and 2nd trial, the height of 1~5 area was lower than that of before. And at 1st and 2nd trial, the height of 6, 7 area was higher than that of before, but there were no significant difference in most. When we compared the results of VAS and MVRS, VAS and MVRS after treatment was significantly decreased compared with that of before(p<0.01). Conclusions: This study shows that oriental diagnosis and treatment for dysmenorrhea patients affects the results of DITI. Further study will be needed.
A Study about Effects of Gamiguibi-tang on Stress and Digestive Disorder of Women Students with Oligomenorrhea
Kim, Mi-Rim ; Kim, Yoon-Sang ; Lee, Yong-Hyun ; Lim, Eun-Mee ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 104~119
DOI : 10.15204/jkobgy.2013.26.2.104
Purpose: The purpose of this study is to recognize menstrual pattern, stress, digestive disorder of female college students who have oligomenorrhea and effects of Gamiguibi-tang. Methods: We researched 30 female students who responded to have menstrual irregulation at
college by questionnaires investigating their menstruation, stress, digestive disorder, and changes of symptoms before and after taking Gamiguibi-tang. Results: 1. There was statistical correlation between menstrual pattern and Qi-Stasis Questionnaire symptoms. 2. There was statistical correlation between menstrual pattern and digestive disorder symptoms. 3. There was statistical correlation between improvement of Qi-Stasis Questionnaire symptoms and usage of Gamiguibi-tang. 4. There was statistical correlation between improvement of digestive disorder symptoms and usage of Gamiguibi-tang. Conclusions: This study showed the stress and digestive disorder symptoms are effectively relieved by Gamiguibi-tang. By this result we expect that Gamiguibi-tang can be used for oligomenorrhea caused by stress or digestive disorder.
Study on Status Survey in Female Infertility Patients Admitted to Korean Medicine Hospital
Kim, Nam-Hoon ; Park, Seung-Hyuk ; Hwang, Deok-Sang ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Lee, Kyung-Sub ; Jang, Jun-Bock ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 120~137
DOI : 10.15204/jkobgy.2013.26.2.120
Purpose: This study was to investigate status survey and cost of infertility patients in
Korean Medicine Hospital. Methods: From January 2012 to June 2012, 171 new patients were admitted to
Korean Medicine Hospital for treatment of infertility. We reviewed their medical records retrospectively and had telephone consultations to find out whether they were pregnant or not. Results: The mean age of outpatients was
years and mean BMI of outpatients was
. 55.0% of patients who did not have childbirth or miscarriage. 82.5% of patients had normal menstrual period. 93.5% of patients visited OB/GYN, 33.3% were treated with ovulation induction, 18.7% underwent intrauterine insemination, and 18.1% underwent in vitro fertilization and embryo transfer. 99.7% were treated with acupuncture and moxibustion, 100% had taken Herbal Medicine. The mean treatment duration of outpatients was
weeks, and the mean medical expense was
won. It was found that 32.4% of patients were pregnant after treatment. Conclusions: We investigated status survey and cost of infertility patients. Further study about Korean medical treatments on infertility is required.
Review on RCT Research Papers Related Nausea and Vomiting in Pregnancy - Focusing on Acupoint Treatment -
Jang, Suk-Woo ; Ahn, In-Suk ; Choi, Min-Sun ; Kim, Dong-Il ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 138~150
DOI : 10.15204/jkobgy.2013.26.2.138
Objectives: To observe randomized controlled trials(RCTs) related to investigating the effects of acupoint treatments on nausea and vomiting in pregnancy to establish the basis of korean medical treatments, and suggest the problems of future clinical research. Methods: After searching for national and international papers published after 2000 and restricting the parameters to 'clinical trial', 'controlled clinical trial', 'randomized controlled trial', then comparing the subjects, methods, research tools, and results to understand the effects and re-comparing the conflicting results to assume the cause. Results: Of the 9 research papers that applied acupressure, four of them used control and experimental groups, and three(75%) research papers indicated significant reduction in vomiting and nausea, and of the seven research papers that utilized the experimental and placebo groups, five(71.4%) reported significant reducing effects. Of the four research papers the used acupuncture treatments, four research papers using control and placebo groups, two showed improvements in symptoms but did not have significant results compared to sham acupuncture groups, and two showed significant reduction of symptoms compared to the control groups. The one research paper that used electrical stimulation showed significant results in the reduction of vomiting and nausea compared to the control group. Conclusions: Acupressure and electrical stimulation showed efficacy reducing the symptoms. Acupuncture treatments did not indicate efficacy some experiments. Therefore it is thought that future acupuncture treatments should use methods that resemble actual clinical medicine to establish efficacy to produce significant results.
A Survey Study on Use Condition of Korean Medical Institution and Demand of Korean Medical Treatment Project of Infertility in Infertile Couple
Choi, Min-Sun ; Lee, Dong-Nyung ; Kim, Dong-Il ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 151~165
DOI : 10.15204/jkobgy.2013.26.2.151
Objectives: The purpose of this study is to investigate use condition of Korean medical institution and demand of Korean Medical Treatment Project of Infertility in infertile couple. Methods: Questionnaires were distributed to all members of the incorporated association AGAYA(http://www.agaya.org/) via e-mail and to infertile women who visited to Korean medicine OB & GY outpatient clinic of university Korean medicine hospitals of the country and an infertility specialized Korean medicine hospital. One hundred twenty four of completed questionnaires were analyzed. Results: 1. Korean medical institution utilization rate of infertile couple was 89.6% and was similar with western medical institution utilization rate of 87.1%. 2. 96.8% of infertile couple answered that Korean Medical Treatment Project of Infertility is necessary. And 90.3% of infertile couple answered that herbal medicines should be supported first of all. 3. 90.3% of infertile couple answered that they will participate if Korean Medical Treatment Project of Infertility go ahead. Conclusions: It was confirmed that most of the infertile couple have been received Korean medical treatment for infertility, and think that Korean Medical Treatment Project of Infertility is necessary.
Investigation of Clinical Research of Acupuncture Treatment on Urinary Incontinence in Medline
Kim, Eun-Gyung ; Hwang, Deok-Sang ; Lee, Jin-Moo ; Lee, Chang-Hoon ; Jang, Jun-Bok ; Lee, Kyung-Sub ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 166~177
DOI : 10.15204/jkobgy.2013.26.2.166
Purpose: The purpose of this study is to examine acupuncture and moxibustion treatment suggested on the papers of urinary incontinence(UI) in medicine journals and to establish the future direction. Methods: The papers which were associated with acupuncture and HG published between 1992 and 2012 in Medline and Scopus were searched. Results: 14 studies met the condition. They were 3 randomized controlled trials(RCTs) and 5 clinical studies. 8 studies revealed that acupuncture and moxibustion have efficacies in UI. Conclusions: From the paper research, acupuncture and moxibustion treatment seem to be effective on UI. However, due to the lack sufficient research of UI, it would be necessary to fulfill further study about the period of acupuncture and moxibustion treatment on UI and the selection of acupoint through well-designed study and establish standard of evidence of them.
A Report on the Effect of Jowisengchung-tang in 2 Cases of Precocious Puberty
Kim, Ji-Eun ; Yang, Seung-Jeong ; Cho, Seong-Hee ; Park, Kyung-Mi ;
The Journal of Oriental Obstetrics and Gynecology, volume 26, issue 2, 2013, Pages 178~187
DOI : 10.15204/jkobgy.2013.26.2.178
Objectives: These cases are that of three girls who are diagnosed as precocious puberty. It seems that the incidence of precocious puberty is rapidly increasing these days. In addition to the psychosocial disturbances associated with precocious puberty, the premature pubertal growth spurt and the accelerated bone maturation result in reduced adult height. The aim of this study was to report the effect of Jowisengchung-tang in 3 cases of precocious puberty. Methods: Retrospective and comparative analysis of 3 children who had been diagnosed with preco cious puberty. Anthropometric measurements including height, weight, body fat, body fat percent, AHP and body mass index were measured. Endocrine investigations including estradiol, luteinizing hormone(LH), FSH were conducted. Pubertal stages were determined with a questionnaire using Tanner stages. Jowisengchung-tang was given to 3 precocious puberty girls. Results: After treatment, the hormone(estradiol index) and accompanying symptoms (breast bud with elevation of breast and papilla; enlargement of areola) were reduced compared with first visit day. Conclusions: We may conclude that Korean traditional treatment of Jowisengchung-tang is effective in patients with precocious puberty and menopausal symptoms.