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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
The Korea Journal of Herbology
Journal Basic Information
Journal DOI :
The Korea Association of Herbology
Editor in Chief :
Volume & Issues
Volume 20, Issue 4 - Dec 2005
Volume 20, Issue 3 - Sep 2005
Volume 20, Issue 2 - Jun 2005
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Studies on the Application for Cosmetics Natural Materials of Folium Perillae
Joe, Woo-A ; Choi, Eun-Young ; Jeung, Soo-Hyun ; Kang, Bo-Yeon ; Son, Jun-Ho ; An, Bong-Jun ; Lee, Chang-Eon ; Jung, Yeon-Suck ; Choi, Kyeong-Im ; Son, Ae-Ryang ; Lee, Jin-Tae ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 1~7
Objectives : In this study, Folium Perillae were examined the possibility to apply as the cosmetics natural materials. Methods : Normal skin softener containing Folium Perillae extracts was manufactured and then its physiological activities function was experimented on. And emollient lotion containing Folium Perillae extracts was manufactured and then it was left under the condition of
, room temperature and
for a month. Then its stability and safety were tested. Results : The physiological activities function of the normal skin softener was almost same with the electron donating ability, SOD like activity and xanthine oxidase inhibitory effect of Folium Perillae extracts. To find the changes of emollient lotion containing Folium Perillae extracts, the emollient lotion was left under the condition of
, room temperature and
for a month. Then, when the emollient lotion was observed with the naked eye, pH, viscosity and particle diameter were measured, its changes were not nearly found. Futhermore, as a result of doing patch test to identify the safety of emollient lotion containing Folium Perillae extracts, there was no stimulus on skin. Conclusions : From the above results, it was expected that the physiological activities of Folium Perillae extracts can be maintained when cosmetics containing Folium Perillae extracts are manufactured. And it was proved that Folium Perillae extracts didn't affect the change of cosmetic when they were applied to cosmetic materials. And it was concluded that emollient lotion containing Folium Perillae extracts was safe for skin.
Anatomical Features of Agarwoods' Xylem
Park, Sang-Jin ; Kim, In-Rak ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 9~18
Objectives : The purpose of this study is to investigate characteristics of cell morphology of two different agar woods (Aquilaria agallocha Roxburgh (AAR) and imitative agar wood (IAW)) using microscopic techniques. Methods : Both light and scanning electron microscopes were used to observe morphological and histological features of the cell of agar woods collected from commercial products in the market. Results : The cell morphology and tissue arrangements of AAR depending on either the adsorption of resin into vessels or no adsorption of resin were observed to compare these features with those of both IAW and Aquilaria sinensis Gilb (ASG). Conclusions : As a result, the vessels of AAR with the resin adsorption was packed with lots of yellow-brownish materials, which were quite different from those of IAW and ASG. The cell walls were thick, and had well-developed traumatic parenchyma tissues with squared cells of the same height and width, which appeared as a clump of small grains packed.
Cytotoxicity and Antioxidant Activities of the Yeonkyo-san and Its ingredients
Lee, Jin-Tae ; Lee, Chang-Eon ; Son, Jun-Ho ; Lee, Jin-Young ; Park, Tae-Soon ; Lee, In-Cheol ; Cheon, Soon-Ju ; Pyeon, Jeong-Ran ; Jee, Seon-Young ; Jo, Cheol-Hun ; An, Bong-Jeun ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 19~27
Objectives : The antioxidant activities of Yeonkyo-san and its ingredient were investigated for industrial application. Methods : We experimented radical scavenging effect, superoxide dismutase and cytotoxicity effect of various cancer cell. Results : The result were obtained as follows : Primary testing of cytotoxicity of Yeonkyo-san and ingredient was done for G361. B16F10, MDA and A549 cell lines. Yeonkyo-san and ingredient water extract, ethanol extract showed cytotoxicity of over 90% respectively against cell line. The electron donating ability(EDA) of water extract from the Yeonkyo-san was higher than 60%, ethanol extract from the Yeonkyo-san was over 80% at 1000 ppm. The electron donating ability(EDA) of water extract and ethanol extract from the Yeonkyo-san ingredients were increased as well. SOD-like activity was high as 75% in 700 ppm, it was increased. All the other samples showed less than 40% SOD-like activity. Conclusions : The results indicated that water extract and ethanol extract of Yeonkyo-san and ingredient can be used as a natural ingredient with biological functions in cosmetic and food composition.
Studies on the Anti-inflammatory and Anti-apoptotic Effect of Catalposide Isolated from Catalpa ovata
Oh, Cheon-Sik ; Hwang, Sang-Wook ; Kim, Yong-Woo ; Song, Dal-Soo ; Chae, Young-Seok ; Jeong, Jong-Gil ; Song, Ho-Joon ; Shin, Min-Kyo ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 29~41
Objectives : The use of natural products with therapeutic properties is as ancient as human civilisation and, for a long time, mineral, plant and animal products were the main sources of drugs. Catalposide, the major iridoid glycoside isolated from the stem bark of Catalpa ovata G. Don (Bignoniceae) has been shown to possess anti-microbial and anti-tumoral properties. Heme oxygenase-1 (HO-1) is a stress response protein and is known to play a protective role against the oxidative injury. In this study, we examined whether catalposide could protect Neuro 2A cells, a kind of neuronal cell lines, from oxidative damage through the induction of HO-1 protein expression and HO activity. We also examined the effects of catalposide on the productions of tumor necrosis
and nitric oxide (NO) on RAW 264.7 macrophages activated with the endotoxin lipopolysaccharide. Methods : HO-1 expression in Neuro 2A cells was measured by Western blotting analysis. NO and
produced by RAW 264.7 macrophage were measured by Griess reagent and enzyme-linked immunosorbent assay, respectively. Results : The treatment of the cells with catalposide resulted in dose- and time-dependent up-regulations of both HO-1 protein expression and HO activity. Catalposide protected the cells from hydrogen peroxide-induced cell death. The protective effect of catalposide on hydrogen peroxide-induced cell death was abrogated by zinc protoporphyrin IX, a HO inhibitor. Additional experiments revealed the involvement of CO in the cytoprotective effect of catalposide-induced HO-1. In addition, catalposide inhibited the productions of
and NO with significant decreases in mRNA levels of
and inducible NO synthase. Conclusions : Our results indicate that catalposide is a potent inducer of HO-1 and HO-1 induction is responsible for the catalposide-mediated cytoprotection against oxidative damage and that catalposide may have therapeutic potential in the control of inflammatory disorders.
Beneficial Effect of Glycyrrhizae Radix Extract on Ischemia-Induced Acute Renal Failure in Rabbits
Kim, Gyung-Ho ; Kim, Min-Ho ; Yun, Yeo-Chung ; Kim, Young-Gyun ; Cho, Su-In ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 43~49
Objectives : The present study was carried out to determine if Glycyrrhizae Radix extract exerts beneficial effect against the ischemia-induced acute renal failure in rabbits. Glycyrrhizae Radix was known to reinforce the function of the spleen and replenish Qi, remove heat and counteract toxicity, dispel phlegm and relieve cough, alleviate spasmodic pain, and to moderate drug actions. It's indications are weakness of the spleen and the stomach marked by lassitude and weakness; cardiac palpitation and shortness of breath; cough with much phlegm: spasmodic pain in the epigastrium, abdomen and limbs: carbuncles and sores. It is often used for reducing the toxic or drastic actions of other drugs. Methods : Antioxidative effect of 3% concentration of Glycyrrhizae Radix extract was measured. Rabbits were treated with Glycyrrhizae Radix extract via i.v., followed by renal ischemia/reperfusion, and the changes of urine volume, serum creatinine levels, glomerular filtration rate(GFR), fractional Na+ excretion
in ischemia/reperfusion induced acute renal failure were measured. Results : Renal ischemia/reperfusion caused increase of serum creatinine level, which was accompanied by a reduction in glomerular filtration rate(GFR). The fractional excretion of
increased in ischemia-induced animals, which was partially prevented by Glycyrrhizae Radix extract treatment. Conclusions : These results indicate that lipid peroxidation plays a critical role in ischemia-induced acute renal failure. Glycyrrhizae Radix extract exerts the protective effect against acute renal failure induced by renal ischemia/reperfusion, and its effect may be attributed to an antioxidant action.
Cytotoxicity and Physiological Activity of SunbangHwalmyung-um
Lee, Jin-Tae ; Lee, Chang-Eon ; Son, Jun-Ho ; Lee, In-Cheol ; Lee, Jin-Young ; Park, Tae-Soon ; Jang, Min-Jung ; Song, Mi-Ae ; Jee, Seon-Young ; An, Bong-Jeun ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 51~58
Objectives : The purpose of this research was physiological activities and investigate cytotoxicity of Sunbanghwalmyung-um extract. Methods : Physiological activity and a cytotoxicity were examined through the hot water and ethanol extracts from Sunbanghwalmyung-um and its ingredient. Results : The electron donating ability(EDA) was 66.9%, 71.3% in 1000 ppm water extract and ethanol extract. Above 90% from 1000 ppm ethanol extract showed a higher activities and it is Rhei Radix et Rhizoma, Lonicerae Flos, Gleditsiae Spina, Glycyrrhizae Radix, Myrrh. SOD-like activity was weak as 12.24%, 16.62% in 700 ppm. In water and ethanol extracts cytotoxicity were against G361, B16F10, MDA, A549, high cytotoxity over 70%. Rhei Radix et Rhizoma, Gleditsiae Spina, Trichosanthis Radix, Paeoniae Radix Rubra showed high cytotoxicity in water and ethanol extracts. Conclusions : We observed physiological activities and investigated cytotoxicity of Sunbanghwalmyung-um and its ingredients. The results also demonstrated in food or cosmetic industry.
Effects of Gami-Daehwangmokdanpi-Tang against CCK-induced acute pancreatitis
Park, Sung-Joo ; Jeong, Jong-Gil ; Seo, Sang-Wan ; Hwang, Sang-Wook ; Kim, Yong-Woo ; Song, Dal-Soo ; Chae, Young-Seok ; Shin, Min-Kyo ; Song, Ho-Joon ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 59~65
Objective : Daehwangmokdanpi-Tang (DWT) has been frequently used as a remedy for antiinflamation. To evaluate effect of acute pancreatitis by DWT, we examined the effects of DWT on the cholecystokinin-octapeptide (CCK)-induced acute pancreatitis (AP) in rats. Methods : Male Wistar rats weighing 200 to 250 g were divided into three groups. Normal untreated group, in treatment with DWT group; DWT was administered orally, followed by
CCK subcutaneously three times, after 1, 3 and 5 h. This whole procedure was repeated for 5 days. In treatment with saline group, the protocol was the same as in treatment group with DWT. Results : The author determined the pancreatic weight/body weight ratio, the levels of pancreatic HSP (heat shock protein)60 and HSP72 and the secretion of pro-inflammatory cytokines. Repeated CCK treatment resulted in the typical laboratory and morphological changes of experimentally induced pancreatitis. DWT was significantly decreased the pancreatic weight/body weight ratio in CCK-induced AP. Futhermore, The author demonstrated that DWT increased HSP60 and HSP72 compared with CCK-induced AP. Additionally, the secretion of
and the levels of amylase and lipase were lower than that saline. Conclusions : These results suggested that DWT may has a protective effect against CCK-induced AP.
Anti-Oxidative Effects of Scutellariae Radix
Oh, Won-Woo ; Cho, Su-In ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 67~74
Objectives : This study was carried out to determine if Scutellariae Radix have protective effect against cell injury induced by various toxic agents in rat kidney slices. Methods : Water(SWe) and methanol(SMe) extracts were prepared for this experiment. Cell injury was estimated by measuring lactate dehydrogenase(LDH). Lipid peroxidation was examined by measuring malondialdehyde. Results : SMe prevented the LDH release by CCl4, menadione, tert-butyl hydroperoxide and mercury treatment in vitro in kidney slices, but SWe prevented the LDH release by CCl4 and mercury. SMe also prevented reduction in GSH by CCl4 and lipid peroxidation induced by mercury. Conclusions : Thus, SMe may have more powerful efficacy on anti-oxidative effects when compared with SWe. And further studies have to be followed concerned with procedure of extraction of SMe and its change of effects.
Effect of Nodus Nelumbinis Rhizomatis Extract on the Regulation of Regional Cerebral Blood Flow in Rats
Kim, Young-Gyun ; Kwon, Mi-Jung ; Cho, Su-In ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 75~81
Objectives : In brain disorders such as ischemic stroke, the final outcome depends largely on the duration and the degree of the ischemia as well as the susceptibility of various cell types in the affected brain region. In the present study, the effects of Nodus Nelumbinis Rhizomatis Extract(NNRe) were tested for the anti-oxidative action of rCBF. Methods : Regional cerebral blood flow(rCBF) were determined by LDF methods. LDF allows for real time, noninvasive, continuous recordings of local CBF. The LDF method has been widely used to trace hemodynamic changes in the superficial or the deep brain structures in experimental stroke research. Results : NNRe treatment showed no change on rCBF in methylene blue, ODQ and L-NNA pretreated rats. 120 minutes of MCAO and followed reperfusion, 0.1% concentration of NNR treatment improved the altered cerebral hemodynamics of cerebral ischemic by increasing rCBF. Conclusions : The ischemia/reperfusion induced oxidative stress may have contributed to cerebral damage in rats, and the present study provides clear evidences for the beneficial effect of NNR on ischemia/reperfusion induced brain injury.
A Study on Physiological Activities of Coptidis Rhizoma and Application for Cosmetic Ingredients
Lee, Jin-Tae ; Lee, Chang-Eon ; Kim, Jun-Hong ; Son, Jun-Ho ; Kwak, Jae-Hoon ; Lee, Jin-Young ; Park, Tae-Soon ; Bae, Ho-Jung ; Jang, Min-Jung ; Jo, Cheol-Hun ; An, Bong-Jeun ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 83~92
Objectives : The physiological activities of Coptidis Rhizoma investigated for application as a cosmetic ingredients. Methods : We were experimented anti-oxidation effect, growth inhibition ability on cancer cells, antibacterial activity on various kinds of bacteria of skin. Results : The results were obtained as follows : Electron-donating ability(EDA) shows that Coptidis Rhizoma extracted with ethanol(94.51%) gives higher EDA in comparison to that extracted with water in 1000 ppm(63.24%). In the test of SOD-like activity, ethanol extract showed quite more activity with 81.01% in 1000 ppm, while water extract was low in 18.22%. In the inhibition activity of Xathine oxidase, ethanol extract showed higher inhibition activity compared to water extract. In measuring lipid oxidation inhibition ability using fish oil, ethanol extract in 100 ppm showed prominent ability. In the oxidation inhibition effect added with
ion as a oxidation promoter, ethanol extract in 1000 ppm, each in the proportion of 90% and 92%, showed high oxidation inhibition effect compared with water extract. Conclusions : The results indicated that, ethanol extract which is superior in its anti-oxidation and antibacterial effect is useful to be applied in cosmetic industry.
Inhibitory Effect of Aacute Pancreatitis by Patriniae Herba
Park, Sung-Joo ; Jeong, Jong-Gil ; Seo, Sang-Wan ; Hwang, Sang-Wook ; Kim, Yong-Woo ; Song, Dal-Soo ; Chae, Young-Seok ; Shin, Min-Kyo ; Song, Ho-Joon ;
The Korea Journal of Herbology, volume 20, issue 3, 2005, Pages 93~100
Objective : Patriniae Herba (PH) has long been used as a remedy for treating infectious diseases in Korea. In the present experiments, the author examined the effects of PH on the cholecystokinin-octapeptide (CCK)-induced acute pancreatitis (AP) in rats. Methods : Male Wistar rat weighing 200 to 250 g were divided into three groups. Normal untreated group, in treatment with PH group; PH (1g/kg) was administered orally, followed by
CCK subcutaneously three times, after 1, 3 and 5 h. This whole procedure was repeated for 5 days. In treatment with saline group, the protocol was the same as in treatment group with PH. The author determined the pancreatic weight/body weight ratio, the levels of pancreatic HSP60, HSP72 and the secretion of pro-inflammatory cytokines. Methods : Repeated CCK treatment resulted in the typical laboratory and morphological changes of experimentally induced pancreatitis. PH was significantly decreased the pancreatic weight/body weight ratio in CCK-induced AP. Futhermore, the author demonstrated that PH increased HSP60 and HSP72 compared with CCK-induced AP. Additionally, the secretion of
and IL-6 the levels of amylase and lipase were lower than that saline. Conclusions : These results suggest that PH may has a inhibitory effect against CCK-induced AP.