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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Pharmacopuncture
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Journal DOI :
KOREAN PHARMACOPUNCTURE INSTITUTE
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Volume & Issues
Volume 13, Issue 4 - Dec 2010
Volume 13, Issue 3 - Sep 2010
Volume 13, Issue 2 - Jun 2010
Volume 13, Issue 1 - Mar 2010
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Biological Activities of Hominis Placenta Herbal Acupuncture prepared by Hydrochloric Acid Hydrolysis
Seo, Geun-Young ; Lee, Sung-Won ; Park, Sung -Joo ; Kim, Sung-Chul ; Sohn, In-Chul ; Hwang, Sung-Yeoun ; Ahn, Seong-Hun ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 5~12
DOI : 10.3831/KPI.2010.13.2.005
Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by-product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide(
), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease. In this study, we have conducted to investigate the biological activities of Hominis Placenta Herbal Acupuncture by measuring total polyphenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability in vitro. The total polyphenol contents of Hominis Placenta Herbal Acupuncture was
. Elctron donation ability on DPPH was 49.4%. The 2,2`-azinobis-3-ehtlbezothiazoline-6-sulfonic acid radical decolorization (ABTS) was 50.01%, similar 10 the DPPH free radical scavenging. The superoxide dismutase (SOD)-like activities of hominis placenta herbal acupuncture was 50.876%. The nitrite scavenging abilities at pH 1.5, pH 3.0, pH 6.0 were 52.8%, 29.4%, 15.4%, respectively; these abilities decreased as pH increased. We conclude that Hominis Placenta Herbal Acupuncture may be useful as potential sources of antioxidant.
The Effect of the Bujeonghangam-tang Extract on Hepatocellular Carcinogenesis and Hepatic Cirrhosis Induced by Diethylnitrosarnine and CCl
Moon, Young-Ho ; Won, Jin-Hee ; Moon, Goo ; Heo, Rae-Kyong ; Seung, Kee-Moon ; Lee, In-Young ; Jang, Myung-Joon ; Kwon, So-Yeon ; Yu, Deok-Seon ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 13~31
DOI : 10.3831/KPI.2010.13.2.013
Objective : Bujeonghangam-tang(BH) has been used for cure of tumor as a traditional medicine. This study was carried out to clarify the effect of BH extract on hepatocellular carcinogenesis and hepatic cirrhosis induced by Diethylnitrosamine(DENA) and
in Rats. Method : Experimental groups were divided into two, 8th and 12th week groups, and subdivided into four; normal group(Nor), cirrhosis and hepatic cancer inducing control group(Con), and BH extract 320 mg/kg/day(BHA) or 640 mg/kg/day(BHB) administered groups to Con. Results: In the 8th week group: The body weight decreased significantly in Con compared with the Nor. The activities of transaminase, alkaline phosphatase(ALP), and lactacte dehydrogenase(LDH) were significantly increased(p<0.05) in the Con compared with Nor, but decreased in the BHA and BHB compared with Con. Alpha fetoprotein(AFP) were the most increased in the Con compared to BHA and BHB. The results of light microscopical observation, a number of hepatocytes were damaged in the Con compared with Nor and BH extract administerd groups. The number of hepatic p53 positive cells was reduced in the BH extract administered groups. According to the electron microscopical observation, hepatocarcinoma cells were observed distinctly in the Con compared with BH extract administered groups. In the 12 weeks group: The results of body were similar to 8th week groups. The activities of transaminase and ALT were significantly increased(p<0.05) in the Con compared with Nor. LDH was significantly(p<0.05) increased in the Con compared with Nor but significantly (p<0.05) decreased in the BHB. Alpha fetoprotein(AFP) were the most increased in the Con among ex perimental groups. The activities of superoxide dismutase(SOD) were significantly (p<0.05) increased in the Con, but the activities of catalase were not increased(p<0.05) compared with Nor. The number of hepatic p53 positive cells was increased in the Con. The results of electron microscopical observation were similar to 8th week groups. Conclusion : These results suggest that ad ministration of BH extract suppress or retard DENA and
-induced hepatocellular carcinogenesis and hepatic cirrhosis in rats.
Component analysis of cultivated ginseng and mountain ginseng to the change of ginsenoside components in the process of heating and fermentation.
Cha, Bae-Cheon ; Yoon, Hye-Chul ; Lee, Dae-Ho ; Park, Jae-Seuk ; Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 33~49
DOI : 10.3831/KPI.2010.13.2.033
Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, mountain ginseng through component analysis, and to know the change of gin senoside components in the process of heating and fermentation Methods: Comparative analyses of ginsenoside
, Rc, Rd, Re, Rf,
, from the cultivated ginseng 4 and 6 years, and mountain cultivated ginseng were conducted using HPLC (High Performance Liquid Chromatography, hereafter HPLC). And the same analyses were conducted in the process of heating and fermentation using mixed Lactobacillus rhamnosus, Lactobacillus plantarum, Bifidobacterium lactis for 7 days. Results: The change of ginsenosides to the process of red ginseng and fermentation, cultivated ginseng and mountain cultivated ginseng were showed another results. Mountain ginseng showed a lot of change compared with cultivated ginsengs. In the 7 days of fermentation, mountain ginseng showed that ginsenoside
, Rc, and Rd were decreased and increased ginsenoside Re, Rf,
were increased compared with cultivated ginseng Conclusions: It seemed that ginsenosides of mountain cultivated ginseng was better resolved than cultivated ginseng because the difference of structure or distribution of ginsenosides in the condition of fermentation.
Anti-inflammatory Effect of Benincasae Semen Herbal-acupuncture at KI10 on nephritis in rats
Lee, Jeong-Hwan ; Kim, Jeong-Ho ; Kim, Young-Il ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 51~65
DOI : 10.3831/KPI.2010.13.1.051
Objective : This study aimed to evaluate the effects of Benincasae Semen Herbal-acupuncture (BS-HA) at KI10 (Umgok) on nephritis induced by LPS in rat. Methods : Rats with nephritis induced by LPS, were treated with Benincasae Semen Herbal-acupuncture(BS-HA) injection at KI10. Two control groups, N.P. group and saline group, were treated with 26 gauge needle at KI10, 3 times a week. In Saline group normal saline was injected at KI10. To evaluate the effects of Benincasae. Semen Herbal-acupuncture at KI10 on nephritis in rats, WBC, Neutrophils in blood, BUN, Creatinine TNF-
, CINC-1 in serum, urinal volume and creatinine and Total protein in urine, reanl TNF-
, renal MPO were measured and reanl tissue was also analyzed. Results: BS-HA injected at KI10 significantly inhibited WBC and neutrophil in blood. creatinine in serum, and MPO in kidney of LPS-stimulated rats. BS-HA injected at KI10 reduced concentration of neutrophil in renal tissue of LPS-stimulated rats. Conclusion : BS-HA at KI10 has a therapeutic effect for nephritis in LPS-stimulated rat There fore, it is suggested that BS-HA at KI10 may be an useful therapeutics in clinical field after further researches.
The Clinical pilot study of Hwangryunhaedok-tang Pharmacopunctue therapy on Post-stroke depression
Je, Jun-Tae ; Lee, Sang-Kwan ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 67~73
DOI : 10.3831/KPI.2010.13.2.067
Objective : The purpose of this study is to determine the efficacy and safely of Hwangryunhaedok-tang Pharmacopuncture (HHT-PA) therapy on post-stroke depression (PSD) in stroke patients. Methods : Fifteen PSD patients has been recruited and evaluated with liver function test (LFT) and renal function lest (RFT) and depression scales, Beck Depress ion Inventory (BDI) and Hamilton Depression Rating Scale (HAM-D) before and after HHT-PA treatment. Results : HAM-D score significantly decreased after HHT-PA treatment regard less of improving of motor function. But BDI score did not decrease significantly. All results of LFT and RFT were in normal range before and after HHT-PA treatment Conclusion : These results showed that HHT-PA decrease PSD symptoms and has safety on stroke patients, although has no effect on improving of motor impairment.
The Experimental Study on Antibiosis of Decoctions Made by Cassiae Semen, Celosiae Semen and Buddlejae Flos
Seo, Hyung-Sik ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 75~83
DOI : 10.3831/KPI.2010.13.2.075
Objectives : This experimental study was performed to investigate antibiosis of decoctions made by Cassiae Semen(CaS), Celosiae Semen(CeS) and Buddlejae Flos(BF). Methods : Decoctions made by CaS. CeS and BF were prepared. After administering decoctions made by CaS. CeS and BF on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Condida albicans) which cause Keratitis, the size of inhibition zone and MIC(Minimum Inhibition Concentration) were measured Results : The inhibition zone on bacterial species didn`t appear, after administering decoctions made by CaS, CeS and BF. Conclusions : This experimental study is showed that decoctions made by CaS, CeS and BF don`t have antibiosis on bacterial species which cause Keratitis.
Clinical Analysis about Treatment of Myofascial Pain Syndrome(MPS) with Sweet Bee Venom on Hand Paresthesia based on Thoracic Outlet Syndrome
Oh, Sung-Won ; Kim, Byoung-Woo ; An, Joong-Chul ; Yoon, Hye-Chul ; Park, Jae-Seuk ; Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 85~92
DOI : 10.3831/KPI.2010.13.2.085
Objectives: The objective of this study was to compare the effects of Sweet Bee Venom(Sweet BV) Therapy between the hand paresthesia patients with Osteoporosis and without Osteoporosis. Methods: This study was carried out to established the clinical criteria of hand parethesia. The patients who had past history of diabeics, neuropathy induced by alcohol or drug and was positive on Myofacial Pain Syndrome Theory were excluded. 32 patients who had hand paresthesia related with unknown-reason was selected by the interview process. And the effects of treatment were analyzed using VAS score before treatment, after treatment, after 1 month and after 3 months. Results and conclusion: After treatment, While Osteoporosis group decrease from
, Non-Osteoporosis group decrease from
by VAS scores. and After 3 months, While Osteoporosis group increase from
, Non Osteoporosis group increase from
. Non-Osteoporosis group was accordingly more effective than Osteoporosis group after 3 months. So Sweet BV therapy for hand numbness patients without Osteoporosis was e effective than patients with Osteoporosis.
Effect of Auricular Acupress Therapy on Insomnia of Cancer Patients : Randomized, Single Blinded, Placebo Controlled Trial
Jung, In-Sook ; Kim, Jung-Sun ; Yoo, Hwa-Seung ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 93~100
DOI : 10.3831/KPI.2010.13.2.093
Background: Auricular acupressure is one of the traditional health care treatments in oriental medicine. Approximately, 30~40% of the cancer patients have said to be suffering from insomnia and half of them having chronic and severe insomnia at the same time. Insomnia caused cancer patients feel more pain, fatigue, depression and anxiety and it sometimes let the power to have the best of cancer pull down. Objective: To investigate how effective the auricular acupressure treatment to cancer patients suffering from insomnia. Methods: We recruited participants from East-West Cancer Center of Daejeon University. Finally, of the people whose age range from 20 to 75, 12 patients who got less than 40 points from the score of Oh`s sleeping score (OSS) were recruited. Single-blind, randomized pilot study was performed. The treatment group received auricular acupressure treatment (AAT) on active points and the control group had received sham acupressure treatment (SAT) for five times. Sleep parameters were checked by using OSS and numeric rating scale (NRS). We checked the scale everytime, both before and after treatment. We analyzed the data statistically by using independent T-test, paired T-test and analysis of variance (ANOVA) test. (p<0.05) Results: Twelve cancer patients participated in this pilot study and there was no significant difference between control and treatment group. Only 7 of them had completed the whole treatment process, 4 patients of AAT group and 3 participants of SAT. The OSS of AAT group had increased from
and that of SAT group had increased from
. There was no significant difference between them. The NRS of AAT group had increased from
and that of SAT group had increased from
. No significant difference was observed between them. Conclusion: Although both groups did not show significant differences, most of the experimental participants showed increasing OSS and NRS after treatments. Significant participants` number will be needed in the next study.
The Experimental Study on the Effect of Fel Ursi & Bovis Calculus Pharmacopuncture Solution in Bacterial Species which cause Keratitis
Han, Na-Young ; Seo, Hyung-Sik ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 101~110
DOI : 10.3831/KPI.2010.13.2.101
Objectives : This experimental study was performed to investigate the effect of Fel Ursi & Bovis Calculus pharmacopuncture solution(FUBCPS) manufactured by using alcohol/water extraction method for identify ing the use of it as eyedrops. Methods: FUBCPS was manufactured by using alcohol/water extraction method. Measure the size of inhibition zone and MIC(Minimum Inhibition Concentration) after administering FUBCPS on bacterial species. Staphylococcus aureus. Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum and Candida albicans, which cause keratitis. Administering cravit(Levonoxacin medicine) on bacterial species also performed to compare the anti-bacterial potency of this material, measured by using the size of inhibition zone Results : After administering FUBCPS on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans). there was no response to MIC and there was no anti -bacterial potency also. Conclusions : This study suggests that FUBCPS dose not have anti-bacterial effects on bacterial species which cause Keratitis. These study result recommends that we need to research more on herbal medicines of eye drop which have anti-bacterial effects on keratitis
The Clinical Analysis on 32 Cases of Herniated Lumbar Disc Patients according to Lumbar CT scan.
Kim, Jeong-Ho ; Lee, Jeong-Hwan ; Kim, Young-Il ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 111~120
DOI : 10.3831/KPI.2010.13.2.111
Objective: This study is to evaluate the effectiveness of the oriental medicine treatment on lumbar disc herniation. Subjects and Methods : The clinical analysis was done on 32 cases of patients with lumbar disc herniation diagnosed by lumbar CT scan. Patients who admitted In Cheongju Oriental Medicine Hospital from April 2007 to April 2008 were analyzed according to the distribution of sex, age, the period of disease, condition on admission, the symptom on admission, Admission day, the treatment efficacy at discharge day. Results : 1. The forties was the most, the acutest phase the most, the day of 8-14 days the most. 2. Multiple bulging disc in 37.5% of CT scan was the most common, followed by a single HNP was 28.1%. 3. Almost 81 % patients showed effective efficacy under VAS 3 at discharge day. 4. Single bulging and herniated disc were more short admission days than multiple bulging and herniated disc.
The Clinical Observation on 10 cases of patients with Hemifacial Spasm Treated by Soyeom Pharmacupuncture at G20(Pungji)
Heo, Jin ; Lee, Eun-Kyoung ; Kim, Jung-Ho ; Kim, Young-Il ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 121~129
DOI : 10.3831/KPI.2010.13.2.121
Objectives : The main purpose of this research is to evaluate the effect of treatment with Soyeom Pharmacupuncture at G20(Punji) for ten patients with hemifacial spasm. Methods : We have treated them with acupuncture treatment and Soyeom Pharmacupuncture at G20(Pungji), and evaluated the effect by Scott`s scale. Results: After treatment, the grades of spasm intensity classified by Scott`s description were improved in 9 cases. Conclusion : This data suggested that Soyeom Pharmacupuncture at G20(Pungji) for hemifacial spasm was effective and will be attempted to the patients wi1h it.
The case study about Polymyositis patient with respiratory symptoms
Lee, Ki-Su ; Hong, Kwon-Eui ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 131~138
DOI : 10.3831/KPI.2010.13.2.131
Objective : This is a clinical report about the 77-years-old man patient with polymyositis treated by oriental medicine. Methods : The patient was treated by acupuncture and herb medication. The improvement of the patient was judged by MRC scale and CPK, LDH. Results & Conclusions : 1. Patient`s symptoms(paraplegia) rapidly improved. 2. The level of CPK, LDH and Potassium are recovered to the normal range. 3. Associated with respiratory symptoms are getting better.
Two Case Report on Wrist Ganglion Treated with Scolopendrid Pharmacopuncture
Shin, Min-Seop ; Lee, Jin -Bok ; Song, Beom-Yong ;
Journal of Pharmacopuncture, volume 13, issue 2, 2010, Pages 139~143
DOI : 10.3831/KPI.2010.13.2.139
Object : This study was to investigate the clinical effect of Scolopendrid Pharmacopuncture on two patients suffering from Wrist Ganglion. Methods : We treated two patients suffering from Wrist Ganglion with both acupuncture and injection of Scolopendrid Pharmacopuncture. Then we measured the sizes of Wrist Ganglion and Visual Analogue Scale(VAS). Results and Conclusions : We found that the sizes of Wrist Ganglion of the two patients were significantly reduced. Moreover, the pain and discomfort of the wrists of the patients were reported to be reduced. So, we concluded that Scolopendrid Pharmacopuncture has an excellent effect on Wrist Ganglion. However, further studies are needed to investigate its exact effects.