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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Pharmacopuncture
Journal Basic Information
Journal DOI :
KOREAN PHARMACOPUNCTURE INSTITUTE
Editor in Chief :
Volume & Issues
Volume 8, Issue 3 - Dec 2005
Volume 8, Issue 2 - Jun 2005
Volume 8, Issue 1 - Feb 2005
Selecting the target year
Fluorescent Method for Observing Intravascular Bonghan Duct
Lee, Byung-Cheon ; Baik, Ku-Youn ; Johng, Hyeon-Min ; Sung, Baeck-Kyoung ; Soh, Kyung-Soon ; Kang, Dae-In ; Soh, Kwang-Sup ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 5~9
DOI : 10.3831/KPI.2005.8.3.005
Observation of intra-vascular threadlike structures in the blood vessels of rats is reported with the images by differential interference contrast microscope, and fluorescence inverted microscope of the acridine-orange stained samples. The confocal microscope image and the hematoxylin-eosin staining revealed the distinctive pattern of nuclei distribution that clearly discerned the threadlike structure from fibrin, capillary, small venule, arteriole, or lymph vessel. Physiological function of the intra-vascular thread in connection with acupuncture is discussed. Especially, this threadlike duct can be a circulation path for herb-liquid flow, which may provide the scientific mechanism for therapeutic effect of herbal acupuncture.
Literary Study of Hyeolmaek(血脈)
Lee, Jong-Young ; Cho, Byung-Jun ; Kang, Dae-In ; Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 11~19
DOI : 10.3831/KPI.2005.8.3.011
Objectives : This study focused on how the modem blood vessel is defined in Oriental medicine through literary investigation. Methods : Contents from 35 classical texts representing each era were analyzed for the expression of Hyeolmaek and affiliate information, as well as terms used for the current concept of blood vessel. Results : Following results were obtained through investigating literary information on Hyeolmaek. 1. In the Yellow Emperor's Classic, Hyeolmaek is associated with heart and widely used for physiological, pathological, diagnosis, and treatment purposes. 2. During the Song Dynasty, a term Cheonggeun (靑節). is used to describe the vein in the abdomen. 3. During the Ming Dynasty, terms such as Cheonggeun(靑節) and Cheongmaek(靑脈) were used. 4. The term Hyeolmaek was used inclusively for blood, blood vessels, arteries, veins, and as well as meridians.
Experimental study of Triglii semen(巴豆) on the blood in Rats
Kim, Dae-Hyun ; Jeong, Chan-Gil ; Kim, Kwang-Ho ; Soh, Kyeong-Sun ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 21~29
DOI : 10.3831/KPI.2005.8.3.021
In order to Experimental study effects of
on the blood in Rats, we have made rats by administering Animal control chamber for two weeks, then have administered. The results is were summerized as follows: 1. The total cholesterol, triglyceride and Hct, Hb by generally rats oral ingestion by Triglii semen of the sample group were decreased as compared with those of the control group. 2. GOT, GPT by generally rats oral ingestion were increased as compared those of control group. According to the above results, Triglii Semen showed inhibition on decrease of serum total cholesterol and Hb, Hct, WBC, RBC contents as well as inhibition on increase of GOT, GPT.
Protective Effects of near nile Juice Against Carbon Tetrachloride-Induced Acute Hepatotoxicity in ICR Mice
Kim, Hyun-Do ; Lee, Kyu-Jae ; Park, Seong-Kyu ; Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 31~38
DOI : 10.3831/KPI.2005.8.3.031
Objectives : This study was aimed at investigating liver protection mechanism of bear bile juice (Fel Ursi)by inducing liver toxicity through
in mice and evaluated histological and serological findings. Methods : Experiment groups was categorized into untreated normal group,
treated control group, and orally administered bear bile juice experiment group. At the termination of experiment, gross examination of the liver as well as histological findings, and Total protein, Albumin, Total bilirubin, Direct bilirubin SGOT, SGPT, and ALP contents in the serum were evaluated. Results : 1. For gross examination and histological findings,
treated control group showed destroyed lobular structure, increased fibrosis, as well as hepatic cirrhosis. For the group treated with bear bile juice, the lobular structure suffered less damage, and showed lower level of fibrosis and liver cirrhosis compared to the control group. 2. For serum analysis, Total protein and Albumin were significantly increased in the bear bile juice experiment group than the control group. Total bilirubin and Direct bilirubin didn't show significant differences between the two groups. SOOT, SGPT, and ALP were significantly decreased in the normal and bear bile juice experiment groups compared to the control group. Conclusion : Taken together, bear bile juice can be effectively used for recovering the liver functions and further researches must be conducted to verify the efficacies of bear bile juice.
A Comparative Study on the Etfects of 『Palmisoyo-San gamibang』, 『Gyebu-Tang』 and 『Boganyangje』 on the Thyrotoxicosis of Rats
Lee, Yeun-Seong ; Soh, Kyeong-Sun ; Jeong, Chan-Gil ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 39~50
DOI : 10.3831/KPI.2005.8.3.039
In order to study comparatively the effects of "Palmisoyo-San gamibang(八味消遙散加味方)"(AP), "Gyebu-Tang(桂附湯)"(GT) and "Boganyangje(補肝陽劑)" (BG) on the thyrotoxicosis rats, we have made thyrotoxicosis rat model by administration sodium levothyroxine p.o. during 4 days(Control group), and have administered solid extract of AP(236.8mg/200g/day : Sample I group), GT(80mg/200g/day : Sample II group) and BG(70.4mg/200g/day : Sample III group) p.o. to thyrotoxicosis rats during 3 days from 3rd day. We measured the body weight(BW), body temperature(BT), levels of Serum
and TSH after administrating solid extract of AP, GT and BG. The results are summarized as follows: 1. Sample I group showed significantly high increasing rate compared with Control, Sample II and Sample III group, but it showed significantly lower levels of BT,
than those of Control, Sample II and Sample III. group. 2. We could know that AP suppress the alteration of
. 3. Sample II and Sample III group showed opposite results to Sample I group in the BW., BT,
Especially Sample III was significantly higher than Control, Sample I and Sample II, so we could guess that BG stimulates the formation of thyroid hormones. According to the above experimental results, "Palmisoyo-San\;gamibang(八味消遙散加味方)" is assumed to have a curative effect against the thyrotoxicosis rat induced by sodium levothyroxine, and to suppress the alteration of
. And we can suppose that "Boganyangje(補肝陽劑)" has a curative effect against the hypothyroidism.
A Literary Study on Bezoar Bovis
Park, Seong-Kyu ; Park, Jae-Seuk ; Baik, Seong-Il ; Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 51~55
DOI : 10.3831/KPI.2005.8.3.051
Objectives: Literary investigation of existing data was conducted to verify effects of Bezoar Bovis and its herbal acupuncture, and determine quality management through component analysis. Results: Following results were obtained through literary investigation. 1. Bezoar Bovis is dried cystic stone from a cattle. Its characteristics are cool, no toxicity, and bitter taste. Known actions are: quells heat and detoxifies Fire Poison, extinguishes internal movement of Liver Wind and stops convulsion, vaporizes phlegm, and opens orifice. It is mainly used for treating tremor, stroke, delirium, sore throat, oral furuncle, boil, and others. 2. Bezoar Bovis is effective for eliminating liver toxicity, protecting against brain damage, and has anti-microbial activities. 3. Bezoar Bovis is mixed with bear gall bladder and deer musk to be used as herbal acupuncture, and this mixture is effective is invigorating liver functions as well as treating arthritis, headache, and etc. 4. Principal components of Bezoar Bovis are bilirubin-type pigments and cholic acids. The amount of bilirubin can be used as a standard to determine the quality of Bezoar Bovis.
Protective Effect of Gwakhyangjeonggisan Herbal Acupuncture Solution in Glioblastoma Cells: Microarray Analysis of Gene Expression
Lee, Hong-Seok ; Yin, Chang-Shik ; Koh, Hyeong-Gyun ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 57~69
DOI : 10.3831/KPI.2005.8.3.057
Objectives : Neurological disorders have been one of main therapeutic targets of acupuncture. The present study investigated the protective effects of Gwakhyangjeonggisan herbal acupuncture solution (GHAS). Methods : We performed 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in glioblastoma cells, and did microarray analysis with cells exposed to reactive oxigen species (ROS) of hydrogen peroxide by 8.0 k Human cDNA, with cut-off level of 2-fold changes in gene expression. Results : MTT assay showed protective effect of GHAS on the glioblastoma cells exposed to hydrogen peroxide. When glioblastoma cells were exposed to hydrogen peroxide, 24 genes were downregulated. When the cells were pretreated with GHAS before exposure to hydrogen peroxide, 46 genes were downregulated. Many of the genes downregulated by hydrogen peroxide stimulation were decreased in the amount of downregulation or reversed to upregulation. Conclusions : The gene expression changes observed in the present study are supposed to be related to the protective molecular mechanism of GHAS in the glioblastoma cells exposed to ROS stress.
A Literary Study on Moschus
Lee, Kyu-Jae ; Yoon, Hyu-Chul ; Lee, Jin-Seon ; Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 71~77
DOI : 10.3831/KPI.2005.8.3.071
Objective : Literary investigation of existing data was conducted to verify effects of Moschus and its herbal acupuncture, and determine quality management through component analysis. Results : Following results were obtained through literary investigation. 1. Deer musk (Moschus) is dried navel gland secretions of the adult male musk deer. 2. Moschus is known to be effective for treating various febrile diseases, to revive senses, heart and abdominal pain, complications from cerebral hemorrhage, angina, and others. 3. Single dosage of Moschus is between
and should not exceed 1g. Normally taken as powder or pill and may be used externally. 4. Moschus also has protective effects for the liver cells, and experiments revealed possible efficacies for hyperlipidemia, brain damage, hypertension, and etc. 5. For herbal acupuncture usage, Fel Ursi, Bezoar Bovis, and Moschus are used as a mixture (BUM), and it's known to be effective for protecting the liver and treating arthritis. 6. For component analysis of Moschus, aromatic matter 'muscone' should be used as a standard matter.
Stem Cells and Herbal Acupuncture Therapy
Kwon, Ki-Rok ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 79~85
DOI : 10.3831/KPI.2005.8.3.079
Stem cell therapy implies the birth of regenerative medicine. Regenerative medicine signify treatment through regeneration of cells which was impossible by existing medicine. Stem cell is classified into embryonic stem cell and adult stem cell and they have distinctive benefits and limitations. Researches on stem cell are already under active progression and is expected to be commercially available in the near future. One may not relate the stem cell treatment with Oriental medicine, but can be interpreted as the fundamental treatment action of Oriental medicine is being investigated in more concrete manner. When it comes to difficult to cure diseases, there is no boundary between eastern and western medicine, and one must be ready to face and overcome changes lying ahead.
The Clinical Study about Honilirls Placenta Herbal Acupuncture on Bell's Palsy
Lee, Chae-Woo ; Kim, Hong-Gi ; Heo, Sung-Woong ; Jung, Kyoung-Kun ; Ahn, Chang-Beohm ; Song, Choon-Ho ; Jang, Kyung-Jeon ; Kim, Cheol-Hong ; Youn, Hyoun-Min ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 87~97
DOI : 10.3831/KPI.2005.8.3.087
Objectives : This study has been designed and performed to identify the effect on Bell's palsy according to the injection of herbal medicine induced from the Hominis Placenta. Methods : We measured the facial palsy changes of the patients who were admitted for Bell's palsy in the Oriental Medical hospital of Dongeui medical center from 03-01-2004 to 07-31-2004. Bell's palsy patients were divided into two groups. One group(A group) was injected with Hominis Placenta herbal acupuncture. The other group(B group) was injected with normal saline. Then effects of these treatment was evaluated by Yanagihara's unweighted grading system. Results : A group was marked more higher than B group in treatment outcome. we discovered that it is significant differences between two groups after 4 week. Conclusions : These results provided that A group is more effective than B group. For clearly proving the effect of Hominis Placenta herbal acupuncture on Bell's palsy, it is need more sample's number and more treatment's duration.
A Case of Temporomandibular Disorder Patient Treated with Additional Hominis Placenta and Bee Venom Herbal Acupuncture
Seo, Bo-Myung ; Lim, Seong-Chul ; Jung, Tae-Young ; Han, Sang-Won ; Seo, Jung-Chul ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 99~105
DOI : 10.3831/KPI.2005.8.3.099
Objectives : The purpose of this study is to analyze the functional and clinical improvement effect on temporomandibular disorder by additional Hominis Placenta and bee venom herbal acupuncture treatment. Methods : A patient was treated with Hominis Placenta, bee venom herbal acupuncture, simple acupuncture, chiropractic therapy, and herbal medicine. We evaluated the improvement by visual analogue scale(VAS) score, mouth opening range, and X-ray image. Results : The VAS score was significantly decreased and mouth opening range was increased after treatment. X-ray image showed improved change after treatments. Conclusions : We think Hominis Placenta and bee venom herbal acupuncture treatment mainly contributed to the improvement of temporomandibular disorders. Further study is needed for the confirmation of this effect of on temporomandibular disorders.
A Clinical Study of Two Patient with Oligomenorrhea treated Carthami flos of Aqua-Acupuncture
Kim, Kyung-Suk ; Yang, Seoung-In ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 107~113
DOI : 10.3831/KPI.2005.8.3.107
Objectives : The purpose of this study is to report the effect of oriental medicine about two patients with oligomenorrhea. Methods : Two patients had no special abnormality in BC, CBC, UA, ultra-sono, hormonal test in this study are 25-years-old and 26 years-old female who have over 40-days menstrual cycle. They had treated for 49-days, 21-days each by oriental medicine method. Their herb medicine is On-kyung-tang and Gwa-gi-eum. Main acupuncture points are Hapkok(LI4), Kihae(CV6), Gwanwon(CV3), Choksamni(ST36), Samumgyo(SP6) and moxibuation Gwanwon(CV3) and treated Carthami flos of Aqua-Acupuncture 0.05cc at Samumgyo(SP6). Results : After treatment, their menstrual cycle decreased 33-days, 36-days each. And improved dyspepsia, menstrual pain. Conclusions : Oriental medical methods are effective in two patients with oligomenorrhea had no special abnormality in BC, CBC, UA, ultra-sono, hormonal test.
Pilot Study on The Thermographic Change of Seven Acupoints by Digital Infrared Thermographic Imaging
Lee, Yun-Kyu ; Lee, Yoon-Kyoung ; Seo, Bo-Myung ; Yun, Jong-Seok ; Kim, Kyung-Un ; Choi, Sung-Hun ; Lee, Kyung-Min ; Lim, Seong-Chul ; Jung, Tae-Young ; Han, Sang-Won ; Seo, Jung-Chul ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 115~121
DOI : 10.3831/KPI.2005.8.3.115
Objectives : This study was designed to find out the effect of seven acupoints of stroke in cerebrovascular hemiplegia patients. Methods : This study was performed on 6 patients with cerebrovascular hemiplegia (test group) and 6 health persons(control group). We measured temperature of skin surface of test and control group using digital infrared thermographic imaging(D.I.T.I) after acupunture on seven acupoints of stroke. And we calculated difference of skin temperature between healthful and affected side for each groups. Results : There was significant difference in area 3 in both two groups between before and after acupuncture. But in general there Was no significant difference between two groups on thermographic change. Conclusions : This is pilot study, so further studies are required to find out the effect of seven acupoints of stroke in cerebrovascular hemiplegia patients.
A Clinical Study on the Effects of Dong-Qi Acupuncture Treatment for Patents with low back pain and sciatica
Lee, Kwang-Ho ; Kwon, Ki-Rok ; Kang, Mi-Suk ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 123~128
DOI : 10.3831/KPI.2005.8.3.123
Objective : The purpose of this study is to observe the effects of Dong-Qi acupuncture treatment for the patients with low back pain and sciatica. Methods : 60 patients were divided into two, Group A of 30 persons and Group B of 30 persons. Only Group A was treated with Dong-Qi acupuncture treatment, Group B was treated with just Dong-Qi acupuncture treatment. Results : In VAS, Group A is
and Group B is
. In Improvement index, Group A is
and Group B is
. Conclusions : We knew that Dong-Qi acupuncture treatment is more effective.
A Case of Feeling of Cold on Legs Treated with Bee Venom and Scolopendrae Corpus Herbal Acupuncture
Lee, Yoon-Kyoung ; Lim, Seong-Chul ; Jung, Tae-Young ; Han, Sang-Won ; Seo, Jung-Chul ;
Journal of Pharmacopuncture, volume 8, issue 3, 2005, Pages 129~135
DOI : 10.3831/KPI.2005.8.3.129
Objective : This study was designed to investigate the effect of bee venom and Scolopendrae Corpus herbal acupuncture on the feeling of cold on legs. Methods : The patient was managed by bee venom and Scolopendrae Corpus herbal acupuncture, body acupuncture and herbal medicine. The following points were selected : BL40, BL57, BL60; SP6. After bee venom and Scolopendrae Corpus herbal acupuncture treatment, body acupuncture was performed at the same points. We evaluated the patient through Visual Analogue Scale(VAS) and Digital Infrared Thermal Imaging(D.I.T.I). Results : After 12 times of treatment, the patient showed that clinical symptoms was decreased, VAS changed from 10 to 3 and there was also improvement change on D.I.T.I.. Conclusions : According to the results, bee venom and Scolopendrae Corpus herbal acupuncture may have the effects on the feeling of cold on legs. But further studies and required to prove the effects of this methods.