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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Oral Medicine and Pain
Journal Basic Information
Journal DOI :
The Korean Academy of Orofacial Pain and Oral Medicine
Editor in Chief :
Volume & Issues
Volume 33, Issue 4 - Dec 2008
Volume 33, Issue 3 - Sep 2008
Volume 33, Issue 2 - Jun 2008
Volume 33, Issue 1 - Mar 2008
Selecting the target year
Influences of Peroxidase on Lysozyme Activity
Lee, Sang-Goo ; Kim, Hyung-Il ; Kho, Hong-Seop ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 1~8
It is well known that many antimicrobial proteins in saliva interact with each other. The purpose of the present study was to investigate the interactions of lysozyme with peroxidase in the aspects of enzymatic activity in vitro. The interactions of lysozyme with peroxidase were examined by incubating hen egg-white lysozyme(HEWL) with bovine lactoperoxidase(bLP). The influence of peroxidase system on lysozyme was examined by subsequent addition of potassium thiocyanate and hydrogen peroxide. Lysozyme activity was determined by turbidity measurement of a Micrococcus lysodeikticus substrate suspension. Peroxidase activity was determined with an NbsSCN assay. The Wilcoxon signed rank test was used to analyze the changes of enzymatic activities compared with their controls. bLP at physiological concentrations enhanced the enzymatic activity of HEWL(P < 0.05) and its effect was dependent on the concentration of peroxidase. However, HEWL did not affect the enzymatic activity of bLP. Thiocyanate did not affect the enzymatic activity of HEWL, either. The addition of potassium thiocyanate and hydrogen peroxide did not lead to additional enhancement of the enzymatic activity of HEWL. The changes of hydrogen peroxide concentration in the peroxidase system did not affect the enzymatic activity of HEWL. Collectively, despite an in vitro nature of our study, the results of the present study provide valuable information on the interactions of lysozyme and peroxidase in the aspects of enzymatic activity in oral health care products and possibly in the oral cavity.
Detection of Helicobacter Pylori in Saliva of Korean Infant
Ryu, Ji-Won ; Lee, Jang-Keun ; Lee, Yong-Su ; Yoon, Chang-Lyuk ; Ahn, Jong-Mo ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 9~14
Helicobacter pylori(H. pylori) has been associated with the cause of peptic ulcer and gastric cancer. H. pylori infection occur mostly during childhood and increase by aging. In route of transmission, Oral cavity does important role. So we employed this study to elucidate route of transmission by detection of H. pylori in infant saliva. We investigated 20 infants aged below 10 years and 20 teens aged below 20 years as study group and 71 adults aged 20 and over years as control group. H. pylori DNA was isolated from 5(25%) infants aged below 10 years, 6(30%) teens and 17(23.9%) adults by nested polymerase chain reaction(n-PCR). There was no statistically significant difference(P>0.05). The obtained results suggest that H. pylori infection is relatively common in saliva of Korean infant and oral cavity may be reservoir of H. pylori.
The Oral Disease of Inpatient with the Systemic Disease
Yoo, Sang-Hoon ; Jung, Sung-Hee ; Auh, Q-Schick ; Hong, Jung-Pyo ; Chun, Yang-Hyun ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 15~26
Purpose : To investigate the actual conditions of diagnosis and treatment of oral medicine inpatient with systemic disease. Methods : A total of 110 subjects, inpatient due to systemic disease for diagnosis and treatment of oral disease was requested to answer the medical history and dental treatment record. Results : Systemic disease is composed of Non-insulin-dependent diabetes mellitus 26%, Cerebral infarction 25.2%, Intracerebral hemorrhage, Polyarthrosis, Coxarthrosis 4.7%, Nerve root and plexus disorders, Hypertensive heart and renal diseases, Ankylosing spondylitis 2.4%. Chief complain of oral disease is composed of toothache 28.6%, routine check 23%, tooth mobility 8.7%, hypersensitivity 7.1%, periodontal bleeding 6.4%. Oral disease is composed of Gingivitis and periodontal diseases 28.9%, Dental caries 17.1%, Diseases of pulp and periapical tissues 15.1%, Diseases of salivary glands 10.5%, Other diseases of hard tissues of teeth 8.6%, Within Normal Limit 5.3%. Treatment of oral disease is composed of periodontal treatment 17.95%, rejection of treatment 16.67%, medication for halitosis & dry mouth 13.46%, extraction 12.18%, prosthetic treatment 8.97%. Chief complain in oral medicine is composed of oral soft tissue problem 6.4%, craniomandibular disorders 5.6%, halitosis 4%, total 16%. Conclusion : These findings indicate that inpatient due to the systemic disease is significantly correlated to the oral disease. The patients of oral disease interrelationship between inpatient and outpatient of systemic disease should be validated by future research.
The Effects of Fluconazole on Chronic Oral Candidiasis Refractory to Nystatin: Case Report
Lee, Eun-Jin ; Park, Won-Kyu ; Kho, Hong-Seop ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 27~33
Candidiasis, an opportunistic infectious condition caused by the genus Candida, is the most common oral fungal infection in humans. The diagnosis of oral candidiasis can often be made based on recognition of its clinical pattern, but at times there is difficulty in making a clinical diagnosis because of its various manifestations. Several antifungal medications have been developed for managing fungal infections. Despite the availability of several effective antimycotics for the treatment of oral candidiasis, failure of therapy is not uncommon due to the unique environment of the oral cavity, where the flushing effect of saliva and the cleaning action of the oral musculature tend to reduce the drug concentration to sub-therapeutic levels. In this case report, we present two patients diagnosed with chronic hyperplastic candidiasis and median rhomboid glossitis, which are known as rare forms of candidiasis. In both cases, there was a significant reduction of clinical signs and symptoms when fluconazole was prescribed after the failure of initial nystatin therapy.
Effect of Glucose at High Concentrations on the Integrin and Cathepsin Expression of the Cultured Human Periodontal Ligament Cells
Kim, Bang-Soo ; Shin, Je-Won ; Hong, Jung-Pyo ; Jue, Seong-Suk ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 35~40
This experiment was designed to clarify the effect of high concentrations of extracellular glucose on the periodontal ligament cells. The cells were incubated for 24 and 48 hours with
including 1,000 mg/L(control group) and 4,500 mg/L(experimental group) of glucose. Then, the expressions of
integrin, cathepsin-B and -L were examined using RT-PCR method. The results were as follows: 1.
integrin expression was increased after incubation in high glucose media. 2. Cathepsin-B expression was increased after the 24-H incubation with high glucose media, but was decreased after the 48-H incubation. 3. The expression of cathepsin-L was decreased by the high glucose media. Theses results suggest that extracellular glucose at high concentration may be attributed to delayed wound healing in diabetes patients through increase in
integrin and decrease in cathepsins, which lead to accumulation of extracellular matrices and adhesion molecules.
Personality Type Test(MBTI) of the Korean Bruxism Patients
Lee, Hyun-Ae ; Auh, Q-Schick ; Jung, Kee-Taig ; Chun, Yang-Hyun ; Hong, Jung-Pyo ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 41~48
The focus of this study is to analyze the effect of stress on the health of bruxism patients using the MBTI system. The most common personality type will be identified among the bruxism patients and by understanding their personality & their handling of stress, more comprehesive and effective treatment plan can be constructed. The study will also conclude that the type of personality has big effect on the cause of bruxism, and that this will be considered in the treatment plan in this hospital. The result of the study is as follow. First, more bruxism patients were type I than type E. It can be suggested that this result is due to the introversive people maintaining their energy how within themselves, and private are less to likely to release there stress than the expressive people. Second, among the bruxism patients significantly more type T were found compared to type F. This implies the bruxism tend to follow principals, scientific and analysing during decision making rather than basing their decision an meanings, emotions and influences. Thirdly, more bruxism patients clarified into ST in comparison to non-bruxism patients. This is thought to be due to probable increased stress and anxiety following ST people's tendency to more strict and realistic thinking according to effectiveness, evidence-based and productivity. Fourth, the type IJ was the most of the bruxism patients. We can come to the conclusion that decision-oriented introversion people who have hard to change, a thoroughgoing preparation characters are likely to grind their teeth by their detailed characters. Fifth, the type IT was the most of the bruxism patients. Bruxism patients are usually influenced by spirit, easily hearted, awed of relationship and attention. So, their intensity of stress is much bigger because of their personality. The last, Type IS was the most of the bruxism patients. It means that introvert sensitive types who have characters of calm, passive but defence to other's emotion, also neutral, keep moderation, and have cold-heartedness are likely to grind their teeth frequently. In conclusion it is evident that bruxism patients have particular personality types. Precisive, analysing and introversive bruxism patients are expected to have higher sensitivities to stress.
Psychological Analysis of BMS Patients through the SCL-90-R
Jang, Yong-Seok ; Tae, Il-Ho ; Ko, Myung-Yun ; Ahn, Yong-Woo ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 49~57
Personality characteristics of BMS patients were alalyzed psychologically by using the SCL-90-R. 59 BMS patient were subjected at Orofacial pain clinic, Department Of Oral Medicine, Pusan National University Hospital during the period from 2006 to 2007. The control group were subjected at dental clinic during the same period. 1. BMS patients group, Dental new patient group, Adult citizen groups were within normal range. 2. The T-scores of HOS, PHOB,PAR, PSY in BMS patient groups was significantly low. 3. The mean T-scores of male in BMS patients group shows the lowest HOS scale, the mean T-scores of female in BMS patient group shows the lowest PHOB scale. 4. The mean T-scores of female in BMS patients group show higher SOM, O-C, DEP, ANX, PSY scales. 5. As compared with the mean T-scores of acute and chronic group in BMS patients, there was no significant difference of the scales.
Usefulness of RPS4Y Gene on Sex Determination in Human Teeth
Yoon, Wang-Ro ; Ahn, Jong-Mo ; Yoon, Chang-Lyuk ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 59~66
Ribosomal Protein S4Y(RPS4Y) gene is the human sex-linked gene on the Y chromosome. There are a number of reports on the sex determination using RPS4Y gene analysis for prevention and diagnosis in sex-linked disease. Thus RPS4Y gene is a reliable genetic marker for sex determination in forensic medicine. In general, the sex determination of an unidentified body can be achieved based on anatomical characteristics, but sometimes sex determination was considered to be difficult such as pre-adolescent bodies or decomposed, mutilated bodies. In this case, Sex determination using PCR method in human teeth produces good results. Because human teeth have a great structural durability, the DNA well preserved in the teeth. So author isolated nuclear DNA from the 20 human teeth(10 males, 10 females), performed to detect RPS4Y gene by PCR method. Samples were divided four group(10 pulp and 10 dentinal tissue in male, 10 pulp and 10 dentinal tissue in female). It was found that detection of RPS4Y gene for sex determination was possible in all the male pulp tissues and 6 out of 10 male dentinal tissues. But there was not detected in female pulp and dentinal tissues. In the view of this results demonstrates the possibility that detection of RPS4Y gene with other sex chromosome genes from the human teeth is useful to sex determination in forensic medicine.
A Clinical Study on the Taste Threshold of the Patients with Xerostomia
Ko, Myung-Yun ; Kwon, Kyung-Min ; Heo, Jun-Young ; Tae, Il-Ho ; Ahn, Yong-Woo ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 67~73
To investigate the change of taste sensitivity which follows after treatment for xerostomia, from September, 2006 to July, 2007, we categorized the patients, who were diagnosed as xerostomia in Oral Medicine, College of Dentistry, Busan National University, as subject group and from September, 2007 to December. The patients who were not diagnosed as systemic disease were categorized as control group. The results were as follows ; 1. Taste threshold comparison showed the differences at tongue lateral, tongue tip, circumvallate papilla between subject and control. 2. Taste threshold comparison showed no difference in male between subject and control. 3. Taste threshold comparison showed decrease in whole tongue except soft palate in female. 4. Taste threshold comparison showed no difference between first and second visit, but there was a tendency to change in circumvallate papilla.
The Effects of Established-Knowledge of Temporomandibular Disorders on Initial Treatment
Ok, Seung-Joon ; Suh, Bong-Jik ; Tae, Il-Ho ; Ko, Myung-Yun ; Ahn, Yong-Woo ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 75~83
There was a research to make it sure that among the contributing factors, the cognitive factor affects on TMD(temporomandibular disorders) or not, we used a questionnaire on new TMD patients who visited the Department of Oral Medicine at Pusan National University of Hospital(PNUH). Research was to identify the patients' understanding of the TMD. 120 patients who visited PNUH from 2007 June to August were tested and following are the results. 1. Those who were in Jr. college or had higher scholarship showed higher understanding than those with final graduation of high school or had lower scholarship(p=0.129). 2. Percentage of high scorers(score of
) were in Jr. college or had higher scholarship than those with final graduation of high school or had lower scholarship(p=0.098). 3. Both in those who scored higher than average and in those scored lower than average, there was no difference in the rate of previsit to local dental clinic, selection of special treatment(by professor), and attendance to next visit after their conservative treatment. 4. Patients who claimed that their symptom did not change after conservative treatment showed higher rate of pre-visit to local dentist(p=0.107) and selection of special treatment(by professor)(p=0.101) and many of them were in Jr. college or had higher scholarship(p=0.005). 5. The fact the patients who claimed their symptoms did not changed or got worsen had a tendency of higher scholarship showed that understanding of the TMD has little to do with the improvement of symptom and that TMD is a very complicated disease.
Effects of Oral Parafunction on the Stiffness and Elasticity in the Muscles of the Mastication and Facial Expression
Kim, Seung-Ki ; Kim, Mee-Eun ; Kim, Ki-Suk ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 85~95
The purpose of this study was to evaluate the effects of oral habits on the muscles of mastication and facial expression by means of two parameters: muscle stiffness and elasticity. 10 healthy, fully-dentate male subjects in their twenties were selected for this study; all had normal Class I occlusal relationships. Muscle stiffness and elasticity were measured with a tactile sensor(Venustron, Axiom Co., JAPAN) while subjects were asked to relax and perform various parafunctional activities such unilateral clenching(biting the bite force recorder with a force of 50kg on each subject's preferred side), jaw thrusting and lip bracing. The following muscles were examined: temporalis anterior(Ta), masseter(Mm), frontalis(Fr), inferior orbicularis oculi(OOci), zygomaticus major(Zm), superior and inferior orbularis oris(OOrs and OOri) and mentalis(Mn). Paired t-test, Correlation Coefficients, ANOVA and Multiple Comparison t-tests were used for statistical analysis. Unilateral clenching was highly correlated with bilateral stiffness and elasticity of all the muscles tested. Mm was affected by all three oral habits; Ta was affected by unilateral clenching(p<0.05); Zm was affected by unilateral clenching and OOrs, OOri and Mn were most affected by lip bracing(p<0.05). This study indicates that not only the masticatory muscles but also the muscles of facial expression, mainly circumoral muscles, can be significantly influenced by parafunctional activities such as unilateral clenching and lip bracing.
The Effects of Low Level Laser Therapy on Current Perception in Trigeminal Neuralgia Patients
Heo, Jun-Young ; Tae, Il-Ho ; Ko, Myung-Yun ; Ahn, Yong-Woo ;
Journal of Oral Medicine and Pain, volume 33, issue 1, 2008, Pages 97~103
The purpose of this study was to examine the effect of LLLT on current perception threshold in trigeminal neuralgia patients. Affected site and non-affected site was irradiated by GaAlAs diode laser. Current perception threshold was evaluated with
CPT/C before and after LLLT. As an outcomes,CPT were obtained. We made a comparision of these values and the results were as follows. 1. There were no significant difference in CPT between affected site and non-affected site before and after LLLT irradiation. 2. There were no significant difference in CPT between affected site and non-affected site after LLLT irradiation. 3. But, CPT values of
fiber incresed slightly on both site after LLLT irradiation