Go to the main menu
Skip to content
Go to bottom
REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Ginseng Research
Journal Basic Information
Journal DOI :
The Korean Society of Ginseng
Editor in Chief :
Volume & Issues
Volume 12, Issue 2 - Dec 1988
Volume 12, Issue 1 - Jun 1988
Selecting the target year
Distribution of Lipids in Panax ginseng Root
Kim, U-Gap ; Lee, Chang-Seop ; Jeong, Byeong-Gap ;
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 93~103
Diversities of lipid compositions according to the morphological differences of the Panax ginseng root were studied by means of column, thin layer, gas-liquid chromate-graphies and histochemical stainings. Purified lipids from various parts were 1.08-2.23% of dry weight, of which 64.2-73.5% were neutral lipids, 15.4-17.4% were glycolipids and 10.4-19.2% were phospholipids. Especially the contents of neutral lipids were highest in cortex, suggesting to be the presence of lipid ducts only in cortex. Triglycerides, sterol esters and hydrocarbons were abundant in the neutral lipid fractions. Twelve components were identified in the periderm and cortex, but unidentified II, IV and V components were not present in the medulla. The major components of glycolipid freactions were sterol glycoside, digalactosyl diglyceride and esterified sterol glucoside. Phosphatidyl glycerol, phosphatidyl choline and phosphatidyl ethanolamine were major components of phospholipid fractions, And phosphatidyl choline was extreamly much in the periderm and medulla, but phosphatidyl glycerol was largest in quantity in the cortex. Eighteen kinds of fatty acids were identified in the neutral lipid, glycolipid and phospholipid fractions. Linoleic, palmitic, oleic and linolnic acids were the main components of fatty acids. The contents of saturated fatty acids, unsaturated fatty acids and essential fatty acids of each three fractions were different one another regardless of the Periderm, cortex and medulla.
Effect of Ginsenosides on .the Biosynthesis of Low density Lipoprotein Receptor in Cultured Chinese Hamster Ovary(CHO) Cell
Ju, Chung-No ; Gang, In-Cheol ; Lee, Hui-Bong ;
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 104~113
Effect of the purified ginsenoside
on LDL receptor biosynthesis of CHO cell cultured in a high cholesterol medium was investigated . Cholesterol uptake by CHO cell cultured in a medium containing various amounts of cholesterol was traced and found that the cholesterol uptake was proportional to the concentration of cholesterol in the medium, and the population of LDL receptors were proportionally decreased as the increasing cholesterol level in the cell. However, when the CHO cells were cultured in the medium containing ginsenosides, no significant decrease of LDL receptor population occured. The biosynthesis of protein and RNA of the above cells was higher than that of CHO cells cultured in the absence of the ginsenosides, suggesting that the ginsenosides might stimulate LDL receptor bio-synthesis. It was also observed that the ginsenosides stimulated the biosynthesis of estradiol and progesterone from cholesterol in the CHO cell. From the above results, it seemed that the ginsenosides lowers the cholesterol level by stimulating the cholesterol metablism including steroid hormone biosynthesis, resulting in the lowering of inhibitory action of cholesterol on LDL receptor biosynthesis.
Protective Effect of Ginseng on BromobenEene-Induced Hepatotoxicity in Mice
Keun Huh ; Byu ;
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 114~120
We have studied the mechanism by examining the effect of ginseng on the epoxide hydrolase which is catabolized the reactive intermetabolite of bromobenzene, and bromobenzene-induced hepatotoxicity. It was observed that ginseng saponin fraction protects against bromobenzene-induced hepatotoxicity in mice as evidenced 1. increased the epoxide hydrolase activity, 2. lower serum transaminase activity, 3. decreased the formation of lipid peroxide. These results suggested that the inducing effect of ginseng on the epoxide hydrolase is believed to be a possible detoxication mechanism for the bromobenzene toxicity in mice.
Maillard Browning Reaction and Antioxidant Activity of Red Ginseng Stored for Long Periods
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 121~127
Samples of Red Ginseng, which had been. manufactured and packaged by the ' Korean Monopoly Corporation, were stored under ambient temperatures and humidities (12-
and 55-68 percent) during one to nine years to examine their browning reaction and antioxidant activity. The brown-color intensity of the Red Ginseng samples increased significantly according to increasing storage period. The pH of the aqueous extracts of the samples also increased slightly during the storage, The former seemed to indicate that extensive browning reactions had taken place in the samples during the long storage, The browning reactions seem to be due to mutual reactions of by-products in the final stage rather than to reactions between free amino acids and free sugars in the initial stage of the maillard browning reactions during the storage. The reducing powers of aqueous and ethanol extracts and antioxidant activity of ethyl acetate extracts of the Red Ginseng samples increased with increasing storage time, The increase in the reducing power and antioxidant activity appeared to be directly attributable to the increased amounts of nonenzymatic browning reaction products formed progressively during the long storage periods.
The Effect of Ginseng Saponin Fraction on Antioxidant Activity of
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 128~134
The effect of the saponin fraction extracted from Panax ginseng C.A. Meyer on the antioxidant activity of
-tocopherol was investigated in vitro as well as in vivo. Microsomal preparation of rat(Winter, 180-200g) liver was incubated in the mixture containing NADPH,
-tocopherol with and/or without ginseng saponin fraction for 30 minutes and the malondialdehyde formed was assayed and found that the saponin fraction stimulated the antioxidant activity of
-tocopherol cooperatively. It was also realized that the cooperative stimulation of the antioxidant activity of
-tocopherol was most eminent when the concentration of the saponin fraction was around
% in the reaction mixture. Alcoholic suspension of
-tocopherol with and f or without ginseng saponin fraction was administered orally to rats in which the lipid preoccupation was induced by ethanol administration and the lipid peroxide contents of the liver were assayed at certain periods of time after
-tocopherol administration in this animal. From the previous work and present experimental results, it seemed that the saponin fraction accelerated the absorption of
-tocopherol and therefore stimulated the antioxidant activity of
-tocopherol more effectively in the animal body.
The Effect of Ginseng Saponin Fractions with Thyroid Hormone Secretion Regulatory Agents on cAMP Level in Cultured Rat Thyroid Glands
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 135~144
When ginseng saponin fractions were treated with secretion regulatory agents, it increased cAMP level at the case of thyrotropin (but the amounts were small). Total saponin increased cAMP level at DEcAMP and isoproterenol, and decreased the level at carbachol and propranolol, but at NaF it had little effect. When diol saponin or triol saponin were treated with secretion regulatory agents, biol saponin decreased cAMP level but triol saponin increased it except for isoproterenol. Also, in propra%olol, which inhibits the increase of CAMP level, diol and triol saponin showed crossing effect, too. From the above results, ginseng saponin fractions are believed that it has the, effects of promotion or inhibition on cAMP production in the thyroid , both diol saponin and triol saponin have crossing effect on thyroid hormone secretion regulatory agents. The normalizatin action of ginseng saponin fractions is notable at the case of NaF and carbachol.
Correlations among Morphological Characteristics of Panax quinquefolium Plants Grown .in British Columbia, Canada
Smyth, S.R. ; Bailey, W.G. ; Skretkowiez, A.L. ;
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 145~152
Correlations between various morphological characteristics of Panax quinquefolium plants grown in Lytton, British Columbia, Canada were assessed for 1-through 4-year old plants. Root dry weight, the dependent variable, was found to be strongly related to leaf dry weight, leaf length and root length for 1-and 2-year old plants during the middle of the growing season. For 1- and 2-year old plants at the end of the growing season, root dry weight was found to be related to leaf dry weight, leaf length and stem dry weight. For 3 and 4-year old plants, root dry weight was found to be related to leaf dry weight, leaf length and stem dry weight. For 3- and 4-year old plants, root dry weight was found to be related to leaf dry weight. For practical considerations, this latter relationship provides a simple method for selecting superior plants from which seed can be harvested.
Ultrastructure of Normal and Inside White Part in Korea Red Ginseng
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 153~157
Ultrastructure of inside white part was compared with normal part in Korea Red ginseng by scanning electron microscope. The inside white part was in number and smaller inside of starch particle than those in the normal. The large membranous components in the inside white part seemed to be thinner than those in the normal. Thin membranous components may be related to lower protein content as previously reported. Starch particles in red ginseng were flat and amorphous.
Effect of Some Growth Regulators on Growth Efficiency of Panax ginseng
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 158~163
P. ginseng seedlings treated with GA,2,4-D and B-9 (N,N-dimethylsuccinamic acid) were grown under dark. Growth efficiencies (
= (Ro- Rt)/ Ro where St. Ro and Rt are shoot weight, initial root weight and root weight at time 1. respectiv
y) and other r
ated factors and their interr
ationship were investigated.
showed quadratic r
ation with temperature change while
showed negative linear r
depended on more
component. The values of
are almost same.
was greater than that reported previously suggesting large variation between roots. GA greatly increased
in supraoptimum temperature range while B-9 greatly decreased
in all temperature range and
in suboptimum range. Shoot weight showed highly significant positive linear corr
ation with substrate amount in most cases of PGR and temperature and with respiration loss in some cases. Respiration loss showed significant linear corr
only in suboptimal temperature range.
A Rapid Method of Ginsenoside Analysis in HPLC by Pretreatment through the reverse-phase minicolumn
Lee, Mi-Gyeong ; Im, Seon-Uk ; Park, Hun ;
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 164~172
The solvent separation step in the conventional method for quantitative analysis of ginsenosides was substituted by purification through a small reverse-phase
-column resulting in the decrease of analysis time by one fourth. New method showed high recovery of total ginsenosides but low recovery in protopanaxatriol-ginsenosides. Sugars did not affect the recovery by the amount in usual root sample. Coefficient of variation in recovery of ginsenosides was lower in the rapid minicolumn method. Optimum load of ginsenosides to minicolumn was 10 to 15 mg. The rapid minicolumn method showed highly significant correlation with the solvent separation method for dried root and red ginseng. For the rapid minicolumn method a small acryl device was used for the simultaneous extraction of 8 samples. This method appeared to be beneficial in cost and for the health of analyst,
1988년도 학술대회발표논문 초록 -특별강연-
Journal of Ginseng Research, volume 12, issue 2, 1988, Pages 173~181
We have studied the mechanism by examing the effect of ginseng on the epoxide hydrolase which is catabolized the reactive intermetabolite of bromobenzene, and bromobenzene-induced hepatotoxicity. It was observed that ginseng saponin fraction protects against bromo benzene-induced hepatotoxicity in mice as evidenced 1. increased the epoxide hydrolase activity, 2. lower serum transaminase activity, 3. decreased the formation of lipid peroxide. These results suggested that the inducing effect of ginseng on the epoxide hydrolase is believed to be a possible detoxication mechanism for the bromobenzene toxicity in mice.