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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of Ginseng Research
Journal Basic Information
Journal DOI :
The Korean Society of Ginseng
Editor in Chief :
Volume & Issues
Volume 15, Issue 3 - Dec 1991
Volume 15, Issue 2 - Aug 1991
Volume 15, Issue 1 - Apr 1991
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Effects of Ginseng Saponin Fraction and Cyclophosphamide on the Tumoricidal Activity of Mouse Macrophage and the Antitumor Effect
Jeon, Hye-Gyeong ; Kim, Se-Chang ; Jeong, No-Pal ;
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 99~105
This experiment was performed to investigate the effects of ginseng saponin fraction and cyclophosphamide (CY) on the tumor development, the antitumor effect and the tumoricidal activity of mouse macrophage. When mice were treated with saponin or CY following inoculation with Sarcoma 180, tumor development was inhibited and survival ratio increased, and a combination of both treatments further inhibited the tumor development. Tumoricidal activity of macrophage was effectively increased at 10-7% concentration of CY and it was further increased when macrophage was cotreated with saponin and CY. Tumoricidal activity of macrophage was greatest at the third day after inoculating tumor cell. Both saponin and CY increased the chemiluminescence of macrophage, but CY had no effect on releasing TNF, unlike saponin.
Effect of Ginsenosides of Red Ginseng on Lipolytic Action of Toxohormone-L from Cancerous Ascites Fluid
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 106~111
This study was devised to obserL'e the inhibitory effects of 7 kinds of ginsenosides on a lipolytic action of Toxohormone-L. The ginsenosides used in this experiment were -Rbl, -Rbl, - Rc, - Re, - Rgl, and - Rg2 prepared from Korean red ginseng. Toxohormene-L was partially purified by centrifigation from the ascites fluids of Sarcoma-180 bearing mice. In vitro test showed that the inhibitory effect of - Rb2 on the lipolysis by Toxohormone-L was highest percent among other treatments at concentration of 100
/ml and 500
/ml of reaction mixture. And total inhibitory activity (units) of - Rb2 was also highest among other treatments at the same concentration. However, in vivo test, body weight gain of Sarcoma-180 bearing mice decreased significantly by administration of - Rg2 compared to those of the control or other ginsenosides treated groups
Studies on the Absorption and Excretion of Ginsenosldes
Han, Byeong-Hun ; Park, Man-Gi ; Lee, Eun-Sil ;
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 112~116
The metabolic fate of ginsenosides including gastrointestinat absorption, organ distribution, excretion and metabolism in liver was investigated by tracer studies using the radio-labeled ginsenosides. 3H-ginsenosides were shown to be absorbed from the mouse digestive tract and then to be excreted rapidly into urine and/or bile. Bile juice was concluded to play a significant role in absorption of ginsenosides. The total concentration of radioactivity persisted in tissues 24 hrs after oral administration was less than 1.3% of the administered dose and Rbl showed the highest value. The concentrations of radioactivity were relatively high in the liver and kidney. After administration of Rbl radioactivity was detected in the brain. After oral administration of 8H-ginsenosides, major component excreted into urine was found to be the intact ginsenosides and decomposed and/or metabolized products were found in GIT in the case of Rbl. 3H-ginsenoside Rbl was shown to be metabolized in the liver and the metabolite was suggested to be an acylated compound of Rbl by a certain organic acid.
Studies on the Lignan Components of Korean White Ginseng
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 117~119
In continuation of previous isolation of two lignan components, Gomisin A and -N, from Korean Red Ginseng the presence of the two lignans was identified in the hexane extract of Korean White Ginseng by gas chromatographic analysis.
Flavor Components of Panax ginseng Cultured with Pine Tree Leaves Mulch (I)
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 120~123
Flavor components of panax ginseng cultured with pine tree leaves mulch instead of traditional rice straw were examined. The growth of two year old ginsengs grown with two different kinds of mulchs no difference, however, the flavor components of ginseng with pine tree leaves mulch 84 constituents detected showed significantly enhanced contents than those of ginseng with rice straw mulch.
Patterns of Soluble Protein, Reducing Sugar and Ginsenosides in Transformed Calli of Ginseng (Panax ginseng C.A. Meyer
Yang, Deok-Jun ; Choe, Gwang-Tae ; Yang, Deok-Deok ;
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 124~130
This study was conducted to obtain basic information about the transformation of ginseng tissue, identification of opine compound and protein, and saponin production from ginseng callus transformed with Ti-plasmic of AW
obacterium tumefaiens C58. Ginseng crown gall callus induced by pTiC58 could be continuously cultured on the Phytohormone-free medium. The transformation was reconfirmed by the detection and identification of opine compound, from the gall callus. The transformed ginseng callus contained higher amounts of protein than normal callus and the protein pattern of transformed callus was quite different from that of normal callus. The xylose which is not detected in the normal callus and ginseng root was identified in gall callus. The saponin contents of gall callus of ginseng were three times higher than that of normal callus, and ginsenoside composition of the transformed callus was similar to that of the cultivated ginseng root, but quite different from that of normal callus.
Endoplasmic Reticulum and Protein Body Formation in Developing Endosperm Cells of Ginseng Seed
Yu, Seong-Cheol ; Chae, Eun-Ju ; Kim, U-Gap ;
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 131~138
This study was carried out to investigate the development of endoplasmic reticulum and the formation of Protein body in the endosperm cell during seed formation of Panax ginseng C. A. Meyer with electron microscope. In the endosperm cell of early developmental process after pollination, vesicles that contain storage materials produced in rough endoplasmic reticulum incorporated into central vacuole. The central vacuole is gradually subdivided into several small-sized vacuoles and increased in number. Amorphous proteinaceous materials of high electron density are produced in rough endoplasmic reticulum. Rough endoplasmic reticulum increase in number and surround the protein body and vesicles circularly. Spherical proteinaceous granules with limited membrane appeared from the amorphous granules at the peripheral region of the rough endoplasmic reticulum. Gradually, storage materials are accumulated within the vacuole surrounded by spherosomes. Protein bodies are formed by interfusing between vacuoles and vesicles derived from rough endoplasmic reticulum which contained the amorphous protein of high electron density.
Activities of Antioxidative Enzymes in Photobleaching of Leaves from Panax ginseng C. A. Meyer
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 139~143
This study investigated the relations between the photosynthetic rate and the activities of antioxidatile enzymes, glutathione reductase, ascorbate free radical reductase, ascorbate peroxidase, glutathione peroxidase, and ascorbate oxidase, in the leaves of Panax ginseng. Under the normal cultivation condition, Panax in showed lower g1utathione reductase and ascorbate free radical reductase activities the Glycine max. But P ginseng showed higher 91utathione Peroxidase, ascorbate Peroxidase, and ascorbate oxidase activities than C. Panax. Therefore, P. ginseng showed weak activities of reductases for the reduction of the oxidized antioxidants. Under the light intensity of 25 KLux, the reductases showed a decrease of over 75% after 24 hours. But the peroyoxidases decreased about 40%. These results showed that the decrease of reductases acitivities was consistent with the decrease of photosynthetic rate. Therefore, we consider that the regulation of antioxidative enzymes or the application of exogenous antioxidants will be effective means for the protection of photodamage in p. ginseng.
Effect of Light Intensity and Quality on the Growth and Quality of Korean Ginseng (Panax ginseng C.A. Meyer) III. Effects of Light Intensity on the Quality of Ginseng Plant
Cheon, Seong-Gi ; Mok, Seong-Gyun ; Lee, Seong-Sik ;
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 144~151
This study was conducted to elucidate the effects of light intensity using polyethylene (p.E) net shading on the specific gravity, red ginseng quality, sugar and saponin contents of ginseng root. The specific gravity significantly increased in the ginseng roots grown under the P.E net shading as compared with that of common straw shading. The red ginseng quality under the P.E net shading was improved in order of 10, 5, 15, 20, 30% of light intensity and the inside cavity and inside white part decreased remarkably as compared with those of common straw shading. The ginseng roots grown under the P.E net shading at 10% and 15% light intensity showed a significant increase in the total sugar content but a significant decrease in the reducing sugar content at 15% light intensity as compared with those of common straw shading. The amount of total saponin of ginseng roots was increased under the P.E net shading at high light intensity as compared with that of common straw shading and the ginseng roots grown under the P.E net shading at 10% light intensity showed an increase in the diol group saponin but the ratio of PT/PD was decreased. Extract contents of ginseng root under the P.E net shading was higher than those of common straw shading and the roots grown under the P.E net shading at 15% and 20% light intensity resulted in a remarkable increase in extract contents. Keyword Polythylene net shading, specific gravity, red ginseng quality, sugar content, saponin, extract
Overview of World Ginseng Production
Ference, Don ;
Journal of Ginseng Research, volume 15, issue 2, 1991, Pages 152~165
It is estimated that world ginseng production has increased from 3,200 tonnes In 1983 to 5,132 tonnes in 1987. China produced approximately hart of world ginseng production and South Korea's production amounts to 31.9% of world ginseng production. Canadian ginseng production of 114 tonnes in 1987 represents only 2.2% of estimated world production. World ginseng production is projected to increase to 6,856 tonnes by 1992. Canadian production as a proportion of total world production is expected to increase to 3.3% however, North American production overall is projected to decrease 12.0% of world production by 1992. Assuming that the value of each country's production is equal to average export price, the value of world ginseng production is estimated to be $ 443 million The estimated values of Korean, North Anerican and Canadian ginseng production represent $ 198.3million, 977.1 million, and $ 12.5 million, redpectively.