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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of Ginseng Research
Journal Basic Information
Journal DOI :
The Korean Society of Ginseng
Editor in Chief :
Volume & Issues
Volume 17, Issue 3 - Dec 1993
Volume 17, Issue 2 - Aug 1993
Volume 17, Issue 1 - Apr 1993
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The Role of Dopaminergic Fibers on the Action of Psychotropic Drugs in 6-OHDA-treated Rats
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 187~195
We have examined the functional role of central dopaminergic processes on the behavioral pharmacological effects induced by psychotropics and red ginseng saponins of normal rats and compared with that of brain damaged rats. Desipramine and clomipramine produced, a significant depression of the locomotor activity in normal rats, but in brain damaged rats, they did not have any effect throughout the experimental period of 4 hours. Total saponin (50~200 mg/kg), PT (25~50 mg/kg), PD (25~50 mg/kg),
(12.5~50 mg/kg) did not change, and high concentrations of PT (100 mg/kg), PD (100 mg/kg) and
(50 mg/kg) showed a significant decrease in the locomotor activity of one hour after administration but total saponin (100 mg/kg), PD (25~50 mg/kg), Rgl (12.5 mg/kg),
(12.5 mg/kg) markedly increased the locomotor activity of four hour after administration in normal rats. On the other hand, total saponin (50 mg/kg), PT (100 mg/kg) and PD (100 mg/kg) Produced a prominent stimulation of the locomotor activity in brain damaged rats. These results suggest that the inhibition of the locomotor activity induced by antidepressants was not affected by the sensitivity of cerebral DA system, whereas red ginseng saponin showed antifatigue effect and also the stimulation of the locomotor activity induced by red ginseng saponin was mediated by the inhibition of cerebral DA system. These psychotropic action of red ginseng saponins could be responsible for the beneficial effects on conditions of fatigue and decreased alertness.
Comparative Study on the Cytotoxic Activities of Red Ginseng of Korea and China
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 196~202
A study was performed to compare the anticancer effects of Korean and Chinese red ginseng roots. The whole crude extracts or chloroform, methanol and acetone fractions of the crude extracts were added in the culture medium of three cancer cell lines, a mouse leukemia cell line (
), a human colon carcinoma cell line (HT-29) and a human rectal carcinoma cell line (HRT-18), to screen the growth inhibition effects. The results are summarized as follows : 1. Crude extracts of both Korean and Chinese red ginseng roots inhibited the proliferation of all the three cancer cell lines tested in a dose dependent manner. However, the growth inhibition effects of Korean red ginseng extracts were significantly greater than that of Chinese red ginseng. 2. An acetone fraction showed the greatest antiproliferative effects among the 11'hole crude extracts, chloroform, methanol and acetone fractions of the crude extracts. 3. These results suggest that the active antiproliferative components of the crude extracts are present mostly in the acetone fraction.
The Effects of Korean Ginseng (Panax ginseng C.A. Meyer) Extracts and Their Fractions on the Growth of Escherichia coli
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 203~209
This study was conducted to investigate the effects of ginseng extracts and their fractions on the 9rowth of Escherichia coli and its glucose consumption. Considerable amount of impurities such as sugar, Protein, lipids and minerals other than saponins were contained in n-butanol extracts which are generally referred to be crude saponins. Sucrose and maltose were contained as major sugars In ginseng extracts and their water soluble fractions. Arginine and potassium were also contained as major amino acid and mineral in those fractions, respectively. Though the glucose consumption and growth of Escherichia coli were enhanced by ginseng extracts and their water soluble fractions those were retarded by ether soluble fractions and n-butanol fractions.
The Effects of Korean Ginseng (Panax ginseng C.A. Meyer) Extracts and Their Fractions on the Growth and Metabolism of Saccharomyces cerevisiae and Saccharomyces uvarum
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 210~218
This study was conducted to investigate the effects of Korean ginseng extracts and their fractions on the growth of Saccharomyces cerevsiae and Saccharomyces uvamm, their glucose consumption and alcohol production. The growth of both yeasts were stimulated by ginseng extracts and their water soluble fractions, but were supressed by ether extracts and an n-butanol extracts. Their growth were enhanced considerably by low molecular weight fractions (< 1,000) in water solubles. Similar results were also obtained with glucose consumption by yeasts. Substances increasing the growth and glucose consumption by yeasts proved to be a low molecular weight fractions (<1,000) in water solubles not saponins. The production of n-propyl alcohol by yeast was enhanced by adding ginseng extracts into the media, but that of ism-butyl alcohol was suppressed at same condition. Key words
Quality Evaluation by Root Weight Distribution in White Ginseng Package
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 219~223
Assessment of root weight grade system for the numeral definition in Korea ginseng was tried by investigation of 13 boxes of the 15-root-grade of 4-year-old white ginseng as a model. In this case satisfaction to theoretical value was 58% in root weight and 50% in root number. The coefficient of variation (CV) was high (35%) for individual root weight in package. The CV of tap root weight 1 among package is low (7.1%) even though there was no significant correlation between tap root weight : and lateral root weight among roots. The mean percentage of tap root to root weight in each package ranged 61 to 74% with CV range of 16.5 to 33.2%. The CV was not much different between 1st and 2nd lateral root weight and the means was above 60%. Strict practice of numeral definition of root weight grade system will be prerequisite for chemical standardization of Korea ginseng.
Relationship Between Bulk Density and Root Weight in White Ginseng
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 224~227
Weight (g/root) and bulk density (g/
) of tap root in 15-root-grade of 4-year-old white ginseng were investigated by specific gravity and weight-volume method. Bulk density measured by specific gravity ranged from 0.8 to 1.2g/
with almost normal distribution in frequency (number 1 of roots). Bulk density measured by volume-weight method had significant correlation with root weight. The percentage of high bulk density root (above 1.0) showed significant positive correlation with mean root weight or mean bulk density of root weight, indicating that the growth conditions for large root provide the better compactnes of root tissue.
Changes in the Physicochemical Properties of Ginseng by Roasting
Park, Myung-Han ; Kim, Kyo-Chang ; Kim, Jong-Seung ;
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 228~231
Physicochemival properties of ginseng roasted at 170 to
were investigated. Soluble solid contents in roast ginseng increased until
, but decreased at higher temperature than
. Contents of reducing sugar and protein were decreased and pH values were dropped, while optical density, acidic polysaccharide contents, precursor of brown pigments and hydrogen donating activities by DPPH were increased according to increasing in roast temperatures. The color distribution of roast ginseng expressed as Hunter L, a and b values demonstrated that lower L values and higher a values were observed according to higher temperature, but b values were almost not changed.
Effects of Antioxidants on the Photoinhibition in Panax ginseng C.A. Meyer
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 232~235
We investigated the effect of antioxidants (ascorbate, glutathione, and sodium azide), which efEectively inhibited the chlorophyll bleaching of Panax ginseng CA Meyer under the high light intensity, treated by folilar wiping on the early stage of photosynthesis and transpiration of ginseng in the 5000
. Ascorbate and glutathione, endogenous antioxidant, completely recovered ginseng from the photoinhibition, but sodium azide, synthetic quencher, showed negative effect. We assumed that endogenous antioxidants could be available to the protection of the leaf-burning phenomenon of ginseng.
Blue-Light Dependent Chloroplast Rearrangement In Panax ginseng C.A. Meyer
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 236~239
We studied the chloroplast rearrangement, short-term regulation depending on the light conditions in plants, and the characteristic of photosynthic rate as affected by in Panax ginseng C.A. Meyer. The chloroplast rearrangement of ginseng mesophyll cell was induced with the irradiation of blue light (400~500 nm) and through this process the rate of leaf transmittance increased 5~7.5%. The time to reach the maximum value of photosynthesis was shorter above 20 minutes with the blue light irradiation than that of the red light.
Photosynthetic Characteristics of Panax ginseng C.A. Meyer I. Photosynthetic Response to Changes of Light Intensity and Leaf Temperature
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 240~245
This study was conducted with ginseng plants to investigate photosynthetic response to changes of light intensity and leaf temperature.
uptake in diurnal course was highest in the first phase (8 00~5 : 30 Am.) on May 30, 1992. In
uptake related to stomatal conductance, these relationship was synchronized in diurnal course, but relationship between TEX>$CO_2$ uptake and intercellular
concentration in diurnal course was synchronized oppositely. Leaf temperature and light intensity at the highest
uptake were in the range of 23~
) and 95
, respectively. In response to an increasing light intensity under a constant leaf temperature (
uptake was increased throughout the light intensity sequence up to 250
uptake was measured with a series of leaf temperature under a constant light intensity (250
uptake was highest at
as a 4.1
. Similar changes were also observed in stomatal conductance and intercellular
concentration. Evidences from several approaches indicate that synchronization of
uptake, stomatal conductance and intercellular
concentration were closely inter-related and changes of leaf temperature iuluenced the photo-response in photosynthetic processes.
Non-Saponin Fraction from Panax ginseng C.A. Meyer Inhibits Platelet Aggregation
Park, Kyeong-Mee ; Rhee, Man-Hee ; Park, Hwa-Jin ;
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 246~249
Hexane, Hexane/diethylether and chloroform fractions from Panax ginseng C.A. Meyer stroungly inhibitied human platelet aggregation induced by a high dose of thrombin (2
/ml). Chloroform fraction more strongly inhibited the platelet aggregation than the other two fraction among them. There were fatty acid ester and phosphate ester instead of polyacethylene compounds in the chloroform fraction.
Several Physiological Funcitons and Metabolism of Ginsenosides in the Animal Body
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 250~286
A Study on the Cytotoxic Activity of Korean Red Ginseng Against Cancer Cells
Hwang, Woo-Ik ; Lee, Sung-Dong ; Han, Yong-Nam ; Lee, Yun-Tai ;
Journal of Ginseng Research, volume 17, issue 3, 1993, Pages 287~306