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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Herbal Formula Science
Journal Basic Information
Journal DOI :
The Korean Journal of Oriental Medical Prescription
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Volume & Issues
Volume 11, Issue 2 - Dec 2003
Volume 11, Issue 1 - Jun 2003
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Analysis of Introduction to Science of Prescriptions in Teaching Materials Related with Science of Prescriptions at Colleges of Korean Oriental Medicine and Colleges of Traditional Chinese Medicine
Kim Do-Hoy ; Shin Soon-Shik ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 1~18
Science of prescriptions is an important part in the education of Korean Oriental Medicine. In spite of that, there is less agreement on measures for improving the education quality of science of prescriptions. Science of prescriptions can be classified into generalities and particulars. This study sought to present contents that must be incorporated into Introduction to Science of Prescriptions to enhance the quality of education by examining both teaching materials being used in colleges of traditional Chinese medicine and those of Korean oriental medicine and the Introduction part of books related with science of prescriptions. And when this study was carried out, training Korean oriental medicine practitioners and researchers and educators of science of prescriptions was taken into account. It is judged that Introduction to Science of Prescriptions needs to be divided into seven chapters and that each chapter requires containing opinions of ancient doctors and references to lay the basis of learning and revised and practical contents in addition to traditional ones. Chapter One Introduction (Conception, History, Disciplinery, Study, How to Learn, Range of Study, How to Study, Academic Activities) Chapter Two Prescriptions and Selection of Treatment Based on the Differential Diagnosis Chapter Three Prescriptions and Therapeutic Methods (Eight Therapeutic Methods, Sixty Four Therapeutic Methods etc.) Chapter Four Classification of Prescriptions Chapter Five Designing and Modification of Prescriptions (Compatibility, Designing, Modification) Chapter Six Preparation Forms of the Prescriptions (Origin, Charicteristics) Chapter Seven Methods of Decocting and Taking Korean Oriental Herbal Medicines Appendix Tables of Apothecaries' Measures and Weights in Current and Ancient Times
Studies on application of Radix Puerariae main blended Prescription from Donguibogam
Cho Nae-Jin ; Yun Young-Gab ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 19~36
Through investigation on prescriptions from Dongeuibogam with Radix Puerariae as an ingredient, the following conclusions were reached. The 59 prescriptions with Radix Puerariae as an ingredient are mentioned from chapter of Pediatrics to chapter of Intestinal Convulsions. And 85% of those appears from chapter of Pediatrics to chapter of coughs. Prescriptions with Radix Puerariae as the main ingredient are used for skin diseases, cold, epidemics, abscess, diabetes, stroke, feverish diseases, intestinal diseases, weakness and cough. The dosage of Radix Puerariae varies from 0.875g to 11.25g. 3.75g was the most frequently used dosage which accounts 44%. And those with small dosage of 0.875 to 1.125g were for use on infants or pregnant women. The grounding pathology used for prescriptions with Radix Puerariae as an ingredient appeared to be mostly the pathology related to the Six External Qi. Among this, wind with cold(風寒), wind, cold with heat and humidity(風寒署濕), catching cold(傷寒), successively catching cold(兩感傷寒), cold of the Yangmyung and heat clogging(陽明傷寒火鬱), abnormal weather(時令不正) are the majority. Through the prescriptions with Radix Puerariae as an ingredient, it could be concluded Radix Puerariae that has various functions such as sweating and removing rash(發表透疹), exhalation and curing muscular ache(發散解肌), producing body fluid and ceasing thirst(生津止渴), opening abscess and healing the scar(托瘡生肌), removal of fever(解熱), resolving hangover(醒酒). Seungmagalguntang(升麻葛根湯) is used as the base prescription the most, and various prescriptions and herbs are combined according to the case.
Study on The Origin, Explanation and Application of Jihwangeumja(地黃飮子)
Hong Seung-Heon ; Kim Yun-Kyung ; Kwon Dong-Yeul ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 37~44
The source of prescription of Jihwangeumja to treat the mental confusion due to phlegm caused by kidney 'deficiency and Yin and Yang deficiency is found in 'Hwangjesomunseonmyeongronbang
'. The source of prescription of Jihwangeum is found in 'Seongjechongnok
'. Therefore, it seems reasonable to change the prescription to 'Jihwangeum' from 'Jihwangeumja' and to change the source of prescription to 'Seongjechongnok
' from 'Hwangjesomunseonmyeongronbang
'. In addition, 'Jihwangeum' is influenced by 'Naebosan' in 'Cheongeumbang
'. Jihwangeumja gave the substantial influence on the treatment of 'Endogenous wind due to hyperactivity' of Yeopcheonsa. Jihwangeumja supplements the true Yuan, smooths the circulation of the flow inside a body and coordinates the interaction between heart and kidney so that it ultimately eliminates sputum and activates circulation inside a body. If the guideline of diagnosis is accurate, many kinds of diseases can be effectively treated through the principle of treating different disease with the same therapy. In addition, it will be also effectively used for headache after cerebral hemorrhage, trigeminal neuralgia(sore tongue), diabetes insipidus, nervous breakdown, hyperthyroidism, chronic glomerulonephritis, infertility and anemia.
A Study On Symptom, Pathology In Prescription of Ha-Tong from Bangyakhappeun
Eyum Hyun-Sik ; Kim Hui-Soo ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 45~55
From the study of the symptom, pathology in prescription of Ha-Tong from The Bangyakhapeun. I have reserched 163 prescription. It can be concluded as follows. 1. Prescription about Fecal disease which was the most as 11.66% of the whole, following order Internal disease(6.75%), Uterus Disease(5.52%) Sick-by-Cold Disease(5.52%), Eye Disease(4.91%), Blood Disease(4.91%), Unbalanced humoral status Disease(4.91%), Gynecologic Disease(4.91%). 2. The Fecal Disease divide diarrhea and dysentery; The Internal Disease divides with Sik-sang(食傷) Chu-sang(酒傷), Sik-juck-yu-sang-han(食積類傷寒), Carbonic acid, Vomiting acid; The Uterus Disease divides with Urinnary Disadvantage, Urinary retention, Incontinence; The Sick-by-Cold Disease divides with yang-myung-byung(陽明病), sang-han-goi-jng(傷寒壞證), sang-han-bun-gal(傷寒煩渴), sang-han-sum-ou, sang-han-hyul-jng(傷寒血證), sang-han-ja-ri(傷寒自利), sang-han-bun-jo-jng(傷寒煩燥證). 3. The Diarrhea and Dysentery many used o-ryung-san, hwng-gum-jak-yak-tang(黃芩芍藥湯) hyang-ryun-hwan(香連丸) etc, and The Internal Disease many used pyung-we-san(平胃散) as a basic prescripton. 4. The organ problem use the Sil-yuol(實熱) of the liver, stomach, lung, uterus, small intestine; six natural factors problem used the Sil-jng(實證) of the wind, fire, heat, cold, dampness; And used Unbalanced humoral status, lntrnal hurt, qi and blood, seven extream feeling.
The study of Literature Review on the pathological mechanism and Therapeutic methods of sudden coma -Focused on Different opinion of successive dynastic medical group in HwangJeNaeKyung and SangHanRon-
Ryu Hyung-Cheon ; Kwack Jeong-Jin ; Choi Chang-Won ; Lee Gang-Nyoung ; Lee Young-Soo ; Kim Hee-Chul ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 57~90
The result of Bibliographic studies on the pathological mechanism of the sudden coma, we got the conclusion like this. 1. The sudden coma is an acute syndrome that refers to be a sudden fainting, an unconsciousness, an aphasia or a cold clammy limb, and immediately awakes or dies, and awakes in a short time, and if we awake, it doesn't leave over and above a sequela. 2. The clinical presentation of the sudden coma can be summarized as follows : The 1st is a disease raising the sudden death due to unconsciousness accompanied by wry mouth & sudden syncope with coma. The 2nd is simply the state of cold limbs. The 3rd is the meaning of the physique and symptomes of the six meridians. The last is the ancient method of expression in contrast of the beriberi. 3. The pathological mechanism of the sudden coma consists of the toxoid from outside, Qi and Xie, fatigue, damp phegm, the damage from seven emotions and the damage from five mental elements, especially the mental disorder due to the angry energy, causes the problems when the fleming-up of liver fire and the depressed of liver qi raise the physiological disorder. 4. Therapeutic methods of sudden coma are soothing the liver and remove stasis, soothing depression and circulating of the qi, calming the liver and suppressing yang. When that is early stage, at first, we must checking upward adverse flow of the qi after promoting the circulation of qi and awakening, and then, we must regulate excessive deficiency of yin yang by therapy that is based on differentiated in symptoms according to heat & cold, deficiency & excess, and use invigorating herb medicine for supporting vigour.
Study on Application of Radix Thichosanthis Main Blended Prescriptions from Donguibogam
Seo Chang-Woo ; Liu Chen-Duk ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 91~98
Through the research into the date of Radix Thichosanthis main blended 21 kinds of prescriptions Radix Thichosanthis from Donguibogam. This study summrized as follows; The suitable dosage of Radix Thichosanthis per one application is one to two don(about
). Radix Thichosanthis Radix main blended prescriptions broadly use in the symptoms of diabetes, excessive thirst, cabuncles and eye diseases In diabetes and excessive thirst, the structes of Radix Thichosanthis main blended prescriptions are commonly used Seng Mak San(生脈散), Radix Puerariae(葛根), Frectus Schisandrae(五味子), Radix Ophiopogonis(麥門冬) In Furuncles, Carbuncles and Cancer like diseases, the structes of Radix Thichosanthis main blended prescriptions are generally used Kumeunhwasan(金銀花散), Jipaesan(芷貝散), Twonongsan(透膿散).
Effect of Chaihushugansan and Chaihuyigantang on the change of Monoamine Contents in the Hypothalamus of Mice induced by the Immobilization Stress
Ahn Soo-Jin ; Lee Tae-Hee ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 99~114
This study aimed to investigate the effects of Chaihushugansan and Chaihuyigantang on the change of monoamine-contents in the hypothalamus of mice induced by the immobilization stress. Each formula(1.0g/kg) was injected intragastrically to mice 1 hour prior to the immobilzation stress(15 minutes) before measuring the change of monoamine-contents level in mice hypothalamus. The results were as follows: 1. DA content at control group showed significant change. CHSGS group and CHYGT group showed significant decrease.(P<0.05) 2. NE content of the control group was increased than normal group. NE content of the CHYGT group was shown a significant decrease than control group.(P<0.05) 3. DOPAC contents didn't show significant changes at any groups. 4. 5-HT contents didn't show significant changes at any groups. 5. 5-HIAA contents at CHSGS group and CHYGT group showed signifiant changes.(P<0.05, 0.01) These data revealed that chaihushugansan and chaihuyigantang might have the anti-stress effect through the control of DA and NE contents in the hypothalamus.
Bojungikgitang Inhibits LPS Plus
Inflammatory Mediators in RAW 264.7 Macrophages
Jang Seon-Il ; Kim Hyung-Jin ; Kim Young-Jun ; Pae Hyun-Ock ; Chung Hun-Taeg ; Yun Yong-Gab ; Jeong Ok-Sam ; Kim Youn-Chul ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 115~128
Bojungikgitang is the water extracts prepared from Ginseng Radix, Astragali Radix, Angelicae gigantis Radix, Astractylodis Rhizoma alba, Aurantii nobilis Pericarpium, Glycyrrhizae Radix, Bupleuri Radix, Cimicifugae Rhizoma, which has been used for the treatment of indigestion, and immunological disease in oriental countries. In this study, the effects of Bojungikgitang on the productions of nitiric oxide (NO) and prostaglandin
, and the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were examined using RAW 264.7 macrophages activated with
plus lipopolysaccharide (LPS). Bojungikgitang (10-400
g/ml) per se had no cytotoxic effect in unstimulated macrophages, but this compound dose-dependently reduced the release of NO and
caused by stimulation of
. The levels of iNOS and COX-2 protein were markedly suppressed by the treatment with Bojungikgitang in a concentration dependent manner. Moreover, Bojungikgitang also attenuated the production of tumor necrosis factor (TNF)-
, interleukin (1L)-1
and IL-6 in LPS-stimulated RAW 264.7 macrophages. These results suggest that Bojungikgitang decreases the NO and
production in macrophages by inhibiting iNOS and COX-2 expression and these properties may contribute to the anti-inflammatory activity of Bojungikgitang.
Effect of Sachungwhan and its components on acetaminophen induced hepatoxicity in rats
Lee Jae-Eun ; Park Sun-Dong ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 129~149
Liver is an important target of the toxicity of drugs, xenobiotics and oxidative stress. Acetaminophen pverdose causes acute liver injury in both humans and animals. This study was performed to observe the effect of sachunwhan and its component groups on recovery of hepatoxicity in acetaminophen treated rats. The experimental group was divided into 4 groups: sachungwhan(SC), samultang group(SC-1: 當歸, 川芎), chungyul group(SC-2: 龍膽草, 大黃, 梔子), and haepyo group(SC-3:羌活, 防風). Under the same condition Normal group was fed basal diet and water; Control group was injected acetaminophen and fed basal diet for 2 weeks; Experimental groups were injected acetaminophen and fed each extracts for 2 weeks respectively. The results were obtained as follows: 1. In the study on antioxidative defense system in vivo, SC reduced the amount of lipid peroxide in both serum and liver and showed activity on antioxidative enzymes such as catalase, glutathion. Other groups had effect only on glutathion. 2. In the study on hepatotoxicity(GOT, GPT,
-GTP, ALP, LDH, Bilirubin), SC had a significant effect on recovery of hepatoxicity in acetaminophen treated rats. Other groups had no effect except SC-1 having effect on
-GTP. As results shown, only Sachungwhan(SC) has significant effects on recovery of hepatoxicity and antioxidative defense system in vivo. These results suggest that Sachungwhan(SC) made antioxidative defense system active and it seemed to be very important to its effect on recovery of hepatoxicity. In the other hand, Component groups had no effect on recoverv of hepatoxicity and antioxidative defense system in vivo. This was thought that component drugs' cooperative synergy effect would be important to Sachungwhan(SC)'s effects mentioned in this paper.
Effects of Siho(Bupleuri Radix) extracts on serum lipid composition and antioxidant system in rat fed high fat diet
Lee Jang-Cheun ; Lee Eun ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 151~159
Effects of siho(Bupleuri Radix) extracts on lipid composition and antioxidant system were investigated in rat fed high fat diet. body weight gain, concentration of plasma triglyceride, total cholesterol, LDL-cholesterol showed a tendency to decrease in siho(Bupleuri Radix) extracts groups. However, the concentration of HDL-cholesterol showed no significantly different among treatments. Plasma and liver TBARS concentration showed a low values in siho(Bupleuri Radix) extracts groups. Activities of SOD, GSH-Px and CAT showed a tendency to increase in siho(Bupleuri Radix) extracts groups.
Effects of Jakyakgamchotang extract on the Analgesic effect in Mice
Lee Ki-Ok ; Kuk Yun-Beum ; Yun Young-Gab ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 161~170
This study was designed to elucidate the analgesic effects of Jakyakgamchotang and Radix paeinia, Radix Glycyrrhiziae which are the component of Jakyakgamchotang in mice. The analgesic effects were measured by the Whittle's method and hot plate method. The results were as follows ; After the administration of Jakyakgamchotang extrace, the frequency of writhing syndrome was significantly inhibited. After the administration of Radix paeinia extract, the frequency of writhing syndrome was significantly inhibited. After the administration of Radix Glycyrrhiziae extract, the frequency of writhing syndrome was significantly inhibited. After the administration of Jakyakgamchotang extrace, paw licking time and escape time were significantly prolonged. After the administration of Radix paeinia extract, paw licking time was significantly prolonged. After the administration of Radix Glycyrrhiziae extract, paw licking time was significantly prolonged. It is concluded that the analgesic effects of Jakyakgamchotang were found to be more effective than Radix paeinia and Radix Glycyrrhiziae.
Study for the standardization of Os Draconis and comparison composition before and after using processed method on Os Draconis
Lee Jang-Cheon ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 171~195
Objectives: This experimental study has been done to compare the Os Draconis composition before and after using processing method. Os Draconis has a quality for calming the liver meridian function and relaxation the mind. Methods: I studied the Os Draconis and processed Os Draconis by vinegar to compare the compositions and its' character. Results: Os Draconis is not a dinosaur's bone fossil but a mammal's bone fossil which has a Calcite mineral, an Apatite mineral,
O, etc. Os Draconis contains a main ingredients CaO>50.00%. Processed Os Draconis which is heated and soaked in vinegar changes to weak condition Conclusion: Os Draconis is supposed to be a mammal's bone fossil. Some Os Draconis has a radioactive substance like a U, Th so we pay heed to deal with it in a medical clinic.
Changes in transepidermal water loss after medication of Gagampalmultang to 104 patients with atopic dermatitis
Ahn Sang-Hoon ; Lee Jong-Hoon ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 197~204
The skin is a barrier between the living organism and its environment, and this barrier function resides in the stratum corneum. The main function of the stratum corneum is to serve as a barrier preventing the penetration of irritants and transepidermal water loss(TEWL). The rate of transepidermal water loss is a convenient parameter for expressing barrier function. Impaired barrier function was manifested by a greatly increased rate of transepidermal water loss. In atopic dermatitis the rate of transepidermal water lossis greatly increased transepidermal water loss. Medication of Gagampalmultang restored to normal the abnormally high rates of transepidermal water loss in the 104 patients with atopic dermatitis. It specifically plays an important role in regulating barrier function.
Clinical Report of Insamyangwitang in Hyungsang medicine
Park Chan-Ki ;
Herbal Formula Science, volume 11, issue 1, 2003, Pages 205~216
A general review is made on Insamyangwitang(人蔘養胃湯). Following conclusions are drawn from the clinical cases of Insamyangwitang in Hyungsang medicine. 1. Insamyangwitang is composed of four different prescriptions of Huisaentang, Sakoonjatang, Eajintang and Pyungwisan. Huisaentang is usually prescribed for the intestinal convulsion. Sakoonjatang for the deficiency of Ki. Eajintang for retention of phlegm. 2. Insamyangwitang is effective in strengthening the spleen, drying the dampness, warning the middle-warmer to stop vomiting, regulating the flow of Ki, and eliminating phlegm. 3. Insamyangwitang is applicable to malaria caused by cold, intestinal convulsion, abdominal mass, edema, tympanites, Yin syndrome of exogenous febrile disease, distension, lack of appetite, stomachache, and diarrhea. 4. Persons with the following characteristic in Hyungsang are more susceptible to Insamyangwitang : Jung type, Hyul type, fish type, Taium meridian type, white fat damp constitution, person with big mouth, and woman rather than man.