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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Herbal Formula Science
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Journal DOI :
The Korean Journal of Oriental Medical Prescription
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Volume & Issues
Volume 21, Issue 2 - Dec 2013
Volume 21, Issue 1 - Jun 2013
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Study on the Use of `Saengsukron` in `Tangaekpyeon of Donguibogam`
Han, Sang-Gon ; Seo, Young-Bae ; Roh, Seong-Soo ; Choo, Byung-Kil ; Jeong, Gi-Hoon ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 1~12
DOI : 10.14374/HFS.2013.21.2.001
Objectives : Systematize concept of `Saengsukron(生熟論)`, providing theoretical basis for clinical and research purpose. Methods : Herbal medicines listed in `Tangaekpyeon of Dongeuibogam` were studied in the following order ; (i) Search for herbal medicines that has applied heat. (ii) Choose herbal medicine with reference of change before and after heating. And choose herbal medicine with reference on purpose of heating. (iii) Classify herbal medicines with similar patterns. (iv) Catagorize herbal medicine by its effects, side effects, nature of herbal medicines, tastes of herbal medicines, meridian tropism of the herbal medicines, and others(color of herbal medicines, formation of herbal medicines, storage of herbal medicines) (v) Systematize concept of `Saengsukron`. Results : We were able to obtain systematized concept of `Saengsukron(生熟論)`. They are classified by `Saengsasukbo(生瀉熟補)`, `Saenghwalsukji(生活熟止)`, `Saengmusukyu(生無熟有)`, `Sukjeukhyojeung(熟則效增)`, `Sukjeukhyogam(熟則效減)`, `Sukjeukyudok(熟則有毒)`, `Saengdoksukgam(生毒熟減)`, `Saengjunsukwan(生峻熟緩)`, `Saengchangsukso(生脹熟消)`, `Sukjeukwiseong(熟則爲升)`, `Sukjeukwigang(熟則爲降)`, `Sukjeukwion(熟則爲溫)`, `Sukjeukwiryang(熟則爲凉)`, `Saengjosukgam(生燥熟減)`, `Sukjeukbyeonmi(熟則變味)`, `Sukjeukbyeonchwi(熟則變臭)`, `Sukjeukbui(熟則部異)`, `Sukjeukjongsa(熟則從邪)`, `Sukjeukbyeonsaek(熟則變色)`, `Sukjeukbyeonhyeng(熟則變形)` and `Sukjeukbojang(熟則保長)`. Conclusions : In this study, heat processing of herbal medicines confirmed that certain regular changes occur. Based on this, concept of `Saengsukron` could be systematized. Research on `Saengsukron` will help practitioners and researchers.
A Study on Roman Nomenclature of Prescriptions in Herbal Formula Science
Song, Jichung ; Sim, Hyuna ; Eom, Dongmyung ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 13~28
DOI : 10.14374/HFS.2013.21.2.013
Objectives : Term standardization is the most important for knowledge information in every study. There are several tries to make terminology standards in Korean Traditional Medicine(KTM). We, authors took a review on romanized prescription nomenclature of main titles in Herbal Formula Science to criticize the ways of romanized prescription nomenclature. Methods : We extract romanized prescription name from Vol. 11, No. 1 to latest Issue Vol. 21, No. 1, Herbal Formula Science. Results : The Korean Academy of Oriental Medicine Prescription has guideline for romanized prescription nomenclature. However, only 6 out of 147 romanized prescription name are confirmed with guideline. In addition, 58 out of 142 names are italicized without guideline. Also there are several ways of marking for prescription names. Conclusions : For making knowledge information and easy searching for terms, we need normative regulations for romanized prescription nomenclature by the Society of Korean Medicine level.
Semantic Change of Crude Drug Preparations in Korea and Policy Evaluation
Kim, Yun-Kyung ; Cho, Sunyoung ; Kim, Jiyeon ; Kang, Yeonseok ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 29~43
DOI : 10.14374/HFS.2013.21.2.029
Objectives : The aim of this study is reviewing the past legal definition and regulations, to provide basis for the future desirable direction of Korean herbal pharmaceutical industry and national herbal drug policies. Methods : We reviewed how concept of herbal medicinal preparation has been utilized and changed along with various national laws and regulations. And this study also reviewed problems related herbal medicinal preparation policies. Results : Since 1990s, especially inauguration of Korea Food & Drug Administration (KFDA) at 1998, the concept of crude drug preparation has constantly expanded and distorted the scope of herbal medicinal preparations. This resulted in decline of herbal medicinal preparation industry. Conclusions : It means policies related herbal medicinal preparation which was driven steadily during this decade have lost their consistency. Also, it restricted the various medical options which can guarantee people`s health rights.
The Anti-obesity Effect of 5 Herbal Formulas in High Fat Diet Induced Obese Mice
Chun, Jin Mi ; Choi, Goya ; Kim, Dong-Seon ; Sung, Yoon-Young ; Nho, Kyoung Jin ; Kim, Seung-Hyung ; Kim, Ho Kyoung ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 44~52
DOI : 10.14374/HFS.2013.21.2.044
Objectives : Samhwangsasim-tang (SST), Hwangryeonhaedok-tang (HHT), Ukgan-san (UGS), Onjunghwadam-hwan (OHH) and Samul-tang (SMT) have been used for the treatment of various diseases. This study was performed to compare the anti-obesity effects of 5 herbal formulas in high fat diet-(HFD) induced obese mice. Methods : The mice were randomly divided into seven groups that were fed a normal diet (ND), a HFD, a HFD plus SST (HFD + SST), a HFD plus HHT (HFD + HHT), a HFD plus UGS (HFD + UGS), a HFD plus OHH (HFD + OHH), or HFD plus SMT (HFD + SMT) at 300 mg/kg/day for 7 weeks. All groups were assayed for body weights, food efficiency ratio (FER), final liver and fat weight and blood biochemical parameters. Results : The increased body weights, food efficiency ratio (FER), and serum total triglyceride were decreased in HFD + OHH group relative to the same measurements in HFD group. Furthermore, the HFD + SST group significantly reduced FER, liver and abdominal subcutaneous fat weight gains, and serum total triglyceride, whereas HDL-cholesterol level was increased compared to HFD group. Conclusions : These results suggested that HFD + OHH and HFD + SST exert anti-obesity effects in HFD-induced obese mice.
Oryeong-san Ameliorates High Glucose-induced Mesangial Cell Proliferation
Yoon, Jung Joo ; Lee, Yun Jung ; Lee, So Min ; Kim, Dae Hwan ; Lee, Ho Sub ; Kang, Dae Gill ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 53~62
DOI : 10.14374/HFS.2013.21.2.053
Objectives : Diabetic nephropathy is associated with morbidity and mortality of diabetes mellitus patients. Mesangial cell proliferation is known as the major pathologic features such as glomerulosclerosis. Oryeong-san, Korean formula, is widely used for the treatment of nephrosis, edema, and uremia. Oryeong-san is composed of five herbs: Alismatis Rhizoma, Polyporus, Atractylodis Rhizoma Alba, Hoelen, and Cinnamomi Cortex. Methods : The present study was performed to investigate potent inhibitory effect of Oryeong-san on high glucose (HG)-induced rat mesangial cells (RMC) proliferation. Results : RMC proliferation under 25 mM glucose was significantly accelerated compared with 5.5 mM glucose, which was inhibited by Oryeong-san in dose dependent manner. Pre-treatment of Oryeong-san induced down-regulation of cyclins/CDKs and up-regulation of CDK inhibitor, p21waf1/cip1 and p27kip1 expression. In addition, Oryeong-san reduced HG-induced RMC proliferation by suppressed the mitogen-activated protein kinase (MAPK) phospholyration such as extracellular signal regulated kinase (ERK), Jun N-terminal Kinase (JNK), and p38. Oryeong-san significantly suppressed HG-induced ROS production. Conclusions : Oryeong-san consequently inhibited HG-induced mesangial cell proliferation through the inhibition of MAPK and ROS signaling pathway. These results suggest that Oryeong-san may be effective in the treatment of renal dysfunction leading to diabetic nephropathy.
Cytoprotective Effects of Artemisia princeps Extract through Inhibition of Mitochondrial Dysfunction
Choi, Hee Yoon ; Jeggal, Kyung Hwan ; Kim, Young Woo ; Lee, Jung Woo ; Jo, Soo A ; Cho, Il Je ; Kim, Sang Chan ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 63~71
DOI : 10.14374/HFS.2013.21.2.063
Objectives : Artemisia princeps is used as moxa in moxibustion and traditional herbal medicine. And its extracts or compounds is known to have an efficacy of antioxidant, anti-diabete, anti-cancer, anti-inflammation and neuroprotection. This study was performed to investigate the cytoprotective effect of Artemisia princeps extract (APE) against arachidonic acid (AA)+iron-induced oxidative stress on HepG2 cell. Methods : The effects of APE on cell viability has been assessed using MTT assay. And flow cytometric analysis was performed to estimate APE`s effects on mitochondrial function. To investigate its underlying mechanism, related protein was analysed by using immunoblot analysis. Results : Treatment of APE increased relative cell viability, prevented a decline of B-cell lymphoma-extra large (Bcl-xL) and cleavage of poly(ADP-ribose) polymerase (PARP) and procaspase-3, and also protected mitochondrial membrane permeability (MMP) against oxidative stress induced by AA+iron. In addition, APE treatment increased phosphorylation of AMP-activated protein kinase (AMPK) exerts a cytoprotective effect. Conclusions : This results demonstrate that APE has an ability to activation of AMPK which protects cells from AA+iron-induced oxidative stress and restores MMP.
A Study of Disassembling Major Indication Terms into Minimum Meaning Units and Linking to Diseases
Kim, Anna ; Oh, Yongtaek ; Kim, Sangkyun ; Kim, Sanghyun ; Jang, Hyunchul ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 72~80
DOI : 10.14374/HFS.2013.21.2.072
Objectives : Ontology is a good tool to represent the knowledge and has developed for Traditional Korean Medicine(TKM) in Korea Institute of Oriental Medicine. There are a lot of TKM terms, which have a complex meaning, especially major indication terms of medicinal treatment and terms of symptom and disease. These complex meaning terms result in the low linkage between major indication terms of medicinal treatment and terms of symptom and disease in TKM ontology. We studied to enhance the percentage of the linkage among those data in TKM ontology. Methods : We disassembled major indication terms of medicinal treatment into minimum meaning units and then linked them to enhance the percentage of the linkage among medicinal material, formula and disease ontology based on Traditional Korean Medicine. To retain objectivity, several experts of Korean Medicine used a web-based tool that supports users in refining terms and disassembling them into the minimum meaning efficiently. Results : The outcome shows that the percentage of the linkage among medicinal material, formula and disease ontology increased. By linking disassembled major indication terms to symptoms and diseases, the amount of information for medicinal materials and formulas also increased quantitatively in comparison with given formula for diseases in disease ontology. Conclusions : By this study, disassembled data increases the percentage of linkage between diseases and medicinal treatments. And the applicability of TKM ontology is also increased.
Effect of Coptidis Rhizoma Extract on Cytokine Production of Mouse Macrophages
Kim, Bok-Kee ; Han, Hyo-Sang ; Lee, Young-Jong ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 81~89
DOI : 10.14374/HFS.2013.21.2.081
Objectives : The purpose of this study is to observe the effect of Coptidis Rhizoma (CCE-extract of C. chinensis Rhizome) in induction of immune protein on mouse macrophages. Methods : To analyze cytokines interleukin(IL)-
, IL-3, IL-9, IL-12p40, IL-13, IL-17, Monocyte Chemoattractant Protein(MCP)-1 induced by macrophages, mouse macrophages were incubated with CCE and was measured. Results : IL-
measurement, CCE showed significant inhibition only at concentration level of 200
. IL-3, MCP-1 measurement, CCE showed significant inhibition only at concentration level of 100, 200
. IL-9 measurement, CCE showed significant inhibition only at concentration level of 50
. IL-13 measurement, CCE showed significant inhibition only at concentration level of 50, 100, 200
. The IL-12p40, IL-17 levels indicated no changes at 25, 50, 100, 200
on mouse macrophages. Conclusions : CCE did not significantly increased inflammatory cytokines IL-
, IL-3, IL-9, IL-12p40, IL-13, IL-17, Monocyte Chemoattractant Protein(MCP)-1 on mouse macrophages. It was verified CCE does not trigger cytokine related hypersensitivity reaction of organism or exacerbation of acute/chronic inflammatory disease.
The Literature Study of Traditional Diet Therapies on Postpartum Recovery & Lactation in the Joseon Dynasty
Kim, Jung-Eun ; Kim, Byung-Sook ; Ahn, Ji-Young ; Kim, Yun-Kyung ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 90~99
DOI : 10.14374/HFS.2013.21.2.090
Objectives : This study was carried out to investigate the traditional diet therapies for the period of postpartum recovery and lactation and to develop modern postpartum recovery foods. Korean traditional medical treatment for postpartum care focused on treating postpartum obesity, edema, agalactia was studied. Methods : We investigated the documents recorded in the medical classics of "Hyangyakjipseongbang(鄕藥集 成方)", "Donguibogam(東醫寶鑑)" and "Bangyakhappyeon(方藥合編)" published in 1433, 1613 and 1885 respectively in the Joseon Dynasty. Results : First, Radix Angelicae Sinensis was most frequently used to treat the postpartum obesity, and a lot of nourishing herbs including Radix Paeoniae Alba, Radix Astragali, Radix Ginseng, Rhizoma Chuanxiong were also used. Second, Radix Glycyrrhizae, Rhizoma Atractylodis Macrocephalase, Pericarpium Citri Reticulatae, Rhizoma Zingiberis Recens were used to treat the postpartum edema. Third, Radix Rhapontici, Medulla Tetrapanacis, Fructus Trichosanthis etc. were used to treat the postpartum agalactia. Conclusions : Consequently, we hope this study on the prescriptions and herbs for gynecology in "Hyangyakjipseongbang(鄕藥集成方)", "Donguibogam(東醫寶鑑)" and "Bangyakhappyeon(方藥合編)" will provide knowledge for diet therapy model development of postpartum care of the modern times.
The Medicinal Effects of Pork in 『Donguibogam』
Suh, Jung-Min ; Kim, Byung-Sook ; Kim, Yun-Kyung ; Ahn, Ji-Young ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 100~109
DOI : 10.14374/HFS.2013.21.2.100
Objectives : "Donguibogam(東醫寶鑑)" is a medical book of the Joseon Dynasty compiled by Heo Jun and was first published in 1613. It recorded a great deal of prescriptions which contained pork and gave detailed explanations of parts of pork`s natural properties and effects. Pork is widely used as a food ingredient in the world but the traditional medicine community has a contraindication of pork and traditional herbal medicines taken together. The aim of this study was to find the supports to develop pork functional foods for the treatment of diseases in "Donguibogam". Methods : Therefore we investigated the documents recorded in "Donguibogam" about usefulness of pork which were used for not only a food ingredient but also a medicine. Results : "Donguibogam" introduced 25 parts of pork including liver, kidney, stomach, bladder, heart etc, and a variety of taking ways i.e. common usages which are internal, external, common use, and aid use which cure a variety of diseases not a simple food but a therapies food. Conclusions : We confirmed that pork has been used to treat many diseases, so we propose to develop pork functional foods available for prevention and cure of certain diseases.
Antiobese and Antidiabetic Effects of Yookmijihwang-tang-gamibang, a Traditional Polyherbal Formula on the Obese and Type II Diabetic C57BL/6JHam-ob/ob Mice
Kim, Taewoo ; Kang, Seok Bong ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 110~120
DOI : 10.14374/HFS.2013.21.2.110
Objectives : The object of this study was to observe the pharmacological effects of Yookmijihwang-tang-gamibang (Liuweidihuang-tang-jiaweifang, YGB) consisted of 17 types of herbs has been traditionally used in Korean medicine for treating various disorders in clinics, aqueous extracts on the genetically obese and type II diabetic C57BL/6JHam-ob/ob(ob/ob) mice. Methods :Three different dosages of YGB were orally administered, once a day for 28 days to ob/ob mice with ob/ob control and C57BL/6JJms normoglycemic intact mice. Four weeks after treatments of YGB: the changes on the body weight, food consumption, blood glucose levels, leptin and adiponectin contents were observed for monitoring the antiobese and antidiabetic effects of YGB. The effects were compared to those of CLA(conjugated linoleic acid) which improve type II diabetes and inhibit related obesity. Results : After end of 28 days of continuous treatments, ob/ob control showed increases of adipocyte hypertrophy, vasodilated atrophic glomerulus which were detected with marked hyperplasia of pancreatic islets, insulin and glucagon producing cells. These obese and related type II diabetes induced in ob/ob mice were markedly and significantly inhibited by 28 days of continuous treatment of three dosages of YGB. The YGB 50mg/kg showed similar favorable effects on the diabetes and related diabetic complications as compared with CLA 750mg/kg in ob/ob mice of the present study. Conclusions : The results obtained in this study suggest that over 25mg/kg of YGB extracts favorably retarded the obese and type II diabetes in genetically obese and type II diabetic ob/ob mice.
A Study on the Comparative Method of Prescription Using Herb Weight Ratio
Park, Daesik ; Lee, Bookyun ; Lee, Byung Wook ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 121~132
DOI : 10.14374/HFS.2013.21.2.121
Objectives : The objectives of this study is to establish data-base to find out similar herbal formulas with a particular herbal formula by comparing composition ratio of configuring herbs. And this thesis is to analyze differences of prescriptions and find out similar prescriptions by utilizing galenical mass ratio, which is directly related to effectiveness of galenical. Methods : This study was proceeded by using Access 2007 with Window 7(MS) and 2,787 prescriptions of which herbal configuration could be indicated by weight unit were analysed from Donguibogam. We standardize all units of the prescription and input the mass ratio data when entered galenical data. Results : We could confirm a degree of similarity between compared prescriptions and a particular prescription according to the sum of differences of herb weight ratio and similarity ratio. Conclusions : A most similar herbal formula could be searched through comparing multi prescriptions by multi prescriptions of herbal configuration from established herbal formula data-base where herb weight ratio of prescriptions is to be input.
Simultaneous Analysis of Bangpungtongseong-san and Its Antioxidant Effect
Seo, Chang-Seob ; Kim, Ohn Soon ; Shin, Hyeun-Kyoo ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 133~143
DOI : 10.14374/HFS.2013.21.2.133
Objectives : We carry out the simultaneous quantification for quality control of four components in Bangpungtongseong-san (BPTSS) sample. In addition, we assessed the antioxidant effects of BPTSS sample. Methods : The used column for separation and analysis of four compounds was Luna C18 column and column oven temperature was maintained at
. The mobile phase for simultaneous determination consisted of two solvent systems, 1.0% acetic acid in water and 1.0% acetic acid in acetonitrile. High performance liquid chromatography-photodiode array (HPLC-PDA) method for analysis was performed at a flow rate of 1.0 mL/min with PDA detection at 254 and 280 nm. The injection volume was 10
. The antioxidant activities of BPTSS were evaluated by measuring free radical scavenging activities on 2,2`-Azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) and 1-1-diphenyl-2-picrylhydrazyl (DPPH). The inhibitory effects on low-density lipoprotein (LDL) oxidation were evaluated by the formation of thiobarbituric acid relative substances (TBARS) and relative electrophoretic mobility (REM). Results : Calibration curves were acquired with
. The values of limit of detection (LOD) and quantification (LOQ) were 0.06-0.29
, respectively. The amounts of geniposide, liquiritin, baicalin, and glycyrrhizin in BPTSS were 5.06, 7.33, 27.56, and 7.81 mg/g, respectively. The BPTSS showed the radical scavenging activity in a dose-dependent manner. The concentration required for 50% reduction (RC50) against ABTS and DPPH radicals were 72.51
. Furthermore, GMGHT reduced the oxidation properties of LDL induced by CuSO4. Conclusions : The established HPLC-PDA method will be helpful to improve quality control of BPTSS. In addition, BPTSS has potentials as therapeutic agent on anti-atherosclerosis.
Comparative Study of Hwangnyeonhaedok-tang and Geongangbuja-tang on the Plasma Hormones Level in Mice Exposed to Cold Stress
Han, Sang-Yong ; Kang, Han-Ju ; Choi, Eun-Sik ; Lee, Ki-Nam ; Lee, Tae-Hee ; Kim, Yun-Kyung ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 144~157
DOI : 10.14374/HFS.2013.21.2.144
Objectives : The aim of this study was to evaluate the efficacy of Hwangnyeonhaedok-tang (HH) and Geongangbuja-tang (GB) on the plasma hormone level in mice exposed to cold stress. HH and GB are the representative prescriptions of cold and hot property, respectively. Methods : We established cold condition by confining ICR mice to a
cage for 24 hours, ICR mice were given a HH (100, 300, 1000 mg/kg) or GB (100, 300, 1000 mg/kg) extract orally twice a day for three consecutive days. From the second day, they were given cold stress (
) for twenty four hours. To measure the plasma corticosterone, insulin, thyroxine, epinephrine and norepinephrine levels of mice, their blood samples were collected from cardiac puncture, immediately centrifuged at
. The protein level of HSP70 and JNK was examined using western blot analysis in cortex and hypothalamus. Results : Oral administration of GB more significantly reduced plasma corticosterone level raised by cold stress than HH. Gardeniae Fructus (CJ), the constituent of HH, significantly increased the thyroxine level. Western blot analysis showed that cold stress-induced Heat shock protein 70 (HSP70) expression was increased by HH and GB, HH decreased JNK expression and GB increased JNK expression dose-depently in hypothalamus. Scutellariae Radix (HG), Zingiberis Rhizoma (GG) and Aconiti Tuber (BJ) decreased HSP70 in hypothalamus and GG, BJ decreased HSP70 in cortex as well. Conclusions : These results suggest Geongangbuja-tang (GB) is more effective for ameliorating the stress response caused by cold stress.
A Case Report on Nausea, Retching, Vomiting and Postprandial Fullness Treated with Soshiho-tang
Yim, Je-Min ; Lee, Sang-Min ; Kim, Won-Il ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 158~164
DOI : 10.14374/HFS.2013.21.2.158
Objectives : "The purpose of this study is to report the effectiveness of Soshiho-tang(小柴胡湯)" on the patient suffered from nausea, retching, vomiting and postprandial fullness. Methods : We diagnosed the symptoms and the signs of the patient as Soshiho-tang syndrome(小柴胡湯證) according to "Treatise on Cold Damage Disease(傷寒論)". We prescribed Soshiho-tang with acupuncture and moxibustion for about 2 weeks. Results : The subjective assessments of the nausea and postprandial fullness had improved. And the frequencies of the retching and vomiting had decreased. Conclusions : We suggest that Soshiho-tang has effectiveness on nausea, retching, vomiting and postprandial fullness in patient diagnosed as Soshiho-tang symptom.
Effects of Maekmundong-tang on the Improvement of Lung Capacity
Park, Dong-Il ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 165~172
DOI : 10.14374/HFS.2013.21.2.165
Objectives : This experiment was performed in order to study the effect of Maekmundong-tang on dyspnea patients. Methods : This study involved 14 dyspnea patients from March 1, 2012 to May 31, 2012. Lung capacity of the patients is evaluated with Peak flow meter. Results : Maekmundong-tang administration was revealed effect on dyspnea patients` lung capacity. Conclusions : It was found that Maekmundong-tang administration was effective on dyspnea patients` lung capacity. The mean degree of improvement was 21.79(L/min). It was shown that the more mild dyspnea level was, the more effective and short-term administration more effective.
A Case Report on Asthma Which was Diagnosed as Han-po-youl
Lee, Su-Hyoun ; Sun, Yung-Chen ; Lee, Seon-Yeop ; Park, Bong-Woo ; Byun, Sung-Bum ; Jeong, Ji-Ye ; Lee, Si-Hyeong ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 173~180
DOI : 10.14374/HFS.2013.21.2.173
Objectives : A 55-year-old male patient whose symptoms were not improved by western drugs(including steroids) was hospitalized in Korean medical hospital for 22 days. Methods : This patient was diagnosed as Han-po-yeol(寒包熱) and treated with herbal decoctions, acupuncture, and moxibustion. And he answered the quality of life questionnaire for adult Korean asthmatics (QLQAKA) at 1st, 15th, and 22th day of hospitalization. Results : After 2 weeks herbal medical treatment, score of QLQAKA was increased by 0.53 point. Conclusion : This result suggest that Korean medical treatment has the potential for asthma patients who did not responded to western drugs.
Case Study of the Patient Considering Chronic Renal Failure Treated with Bojungikki-tang and Bojungikki-tang gamibang
Nam, Woo-Jin ; Bae, Su-Hyun ; Park, Sun-Young ; Jung, So-Youn ; Park, Dong-Il ;
Herbal Formula Science, volume 21, issue 2, 2013, Pages 181~186
DOI : 10.14374/HFS.2013.21.2.181
Objectives : The purpose of this study is to report the clinical effect of herbal medicine on the patient considering chronic renal failure. The patient complained of hemiparesis, general weakness, anorexia, nausea and dizziness. Methods : According to the traditional Korean medicine syndrome differentiation, the patient was classified as Deficiency of Spleen Qi and prescribed Bojungikki-tang and Bojungikki-tang gamibang as well as acupuncture and moxibustion treatment. Changes of BUN, creatinine, VAS for genaral weakness, nausea, dizziness were compared before and after treatment for 2 weeks. Results : After treatment, the level of BUN and creatinine was decreased and main symptoms were improved. Conclusions : Herbal medicine Bojungikki-tang and Bojungikki-tang gamibang with acupuncture and moxibustion treatment would be efficient to the patient of chronic renal failure.