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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of the Korean Academy of Child and Adolescent Psychiatry
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Korean Academy of Child and Adolescent Psychiatry
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Volume & Issues
Volume 18, Issue 2 - Oct 2007
Volume 18, Issue 1 - Apr 2007
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The Korean Practice Parameter for the Treatment of Pervasive Developmental Disorders : Development and Implications
Ahn, Joung-Sook ; Koo, Young-Jin ; Son, Jung-Woo ; Yoo, Han-Ik K. ; Yoo, Hee-Jeong ; Chung, Un-Sun ; Cho, In-Hee ; Ahn, Dong-Hyun ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 85~87
The new research data and rapid development of psychotropic drugs over the past few years have warranted the development of clinical practice guidelines for managing pervasive developmental disorder(PDD). These guidelines are urgently needed due to the recent changes in social circumstances and clinical situations in Korea. Despite the many limitations and problems surrounding the development of these guidelines, the Korean Academy of Child and Adolescent Psychiatry(KACAP) has decided to develop the Korean Practice Parameters for the Treatment of PDD. The goal, basic principles, organization, and implications of this development project are introduced in this special paper. We expect these practice parameters to be a useful reference not only for child psychiatrists and other healthcare professionals in clinical practice, but also for the autistic patients themselves and their caregivers. The practice parameters shall be revised and improved in the near future.
The Korean Practice Parameter for the Treatment of Pervasive Developmental Disorders : Clinical Manifestation, Epidemiology, Course, Causes, and Comorbidity
Yoo, Han-Ik ; Cho, In-Hee ; Yoo, Hee-Jeong ; Koo, Young-Jin ; Chung, Un-Sun ; Ahn, Joung-Sook ; Ahn, Dong-Hyun ; Son, Jung-Woo ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 88~96
Pervasive developmental disorders are characterized by lifelong impairments in fundamental social and/or communication skills and by the presence of seemingly purposeless and repetitive behaviors, interests, or activities. A number of possible biological etiologies, including genetic, structural and functional brain abnormalities, have been identified in patients with pervasive developmental disorders. In addition, clinicians should take the possibility of comorbid psychiatric conditions into consideration when making the differential diagnosis of pervasive developmental disorders.
The Korean Practice Parameter for the Treatment of Pervasive Developmental Disorders : Diagnosis and Assessment
Yoo, Hee-Jeong ; Cho, In-Hee ; Koo, Young-Jin ; Yoo, Han-Ik ; Son, Jung-Woo ; Chung, Un-Sun ; Ahn, Joung-Sook ; Ahn, Dong-Hyun ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 97~108
Multiple areas of development are affected in pervasive developmental disorders(PDD), and assessments of various aspects of behavior and development are essential for diagnosis. The object of this review is to provide the practical guidelines for the assessment of core features of PDD, including abnormalities in communication, social interaction, and repetitive and stereotyped behavior. It covers the issues of differential diagnosis within and outside the PDD category, standardized diagnostic tools, assessment of intellectual and language functions, and the early diagnosis of PDD in infancy. This guideline also stresses the process of medical and neurological evaluation for proper diagnosis of PDD.
The Korean Practice Parameter for the Treatment of Pervasive Developmental Disorders : Pharmacological Treatment
Cho, In-Hee ; Yoo, Han-Ik K. ; Son, Jung-Woo ; Yoo, Hee-Jeong ; Koo, Young-Jin ; Chung, Un-Sun ; Ahn, Dong-Hyun ; Ahn, Joung-Sook ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 109~116
The objective of this review is to establish practice parameters for pharmacological treatment of children and adolescents with pervasive developmental disorders. We performed a detailed review of the literature, including a wide range of controlled clinical trials, open trials, case reports, and side-effect profiles of related drugs. Few medications have a treatment indication for pervasive developmental disorders, and few studies with well-controlled methodology are available for evaluating treatment results. Pharmacological treatments focus on associated target symptoms because symptom reduction may improve educational and social ability and enhance quality of life. Well-controlled trials have been conducted for some SSRI(selective serotonin reuptake inhibitor) antidepressants, risperidone, and methylphenidate, and showed reduction of some target symptoms. Since the medications are not specific to autism and do not treat core symptoms of the disorder, their potential side effects should be carefully considered. Family education is necessary to give proper information on target symptoms, limitation of drug treatments, and risks.
The Korean Practice Parameter for the Treatment of Pervasive Developmental Disorders : Non-Pharmacological Treatment
Koo, Young-Jin ; Cho, In-Hee ; Yoo, Hee-Jeong ; Yoo, Han-Ik K. ; Son, Jung-Woo ; Chung, Un-Sun ; Ahn, Dong-Hyun ; Ahn, Joung-Sook ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 117~122
Practice parameters for non-pharmacological treatment of children and adolescents with pervasive developmental disorders are based on the scientific literature for evidence-based practices. Appropriate educational and behavioral interventions are important in improving the long-term outcome in pervasive developmental disorders. Early and sustained intervention appears to be particularly important. The goal for interventions is to gain pragmatic skills for verbal communication, playing with peers, daily living routines, self-management, and social adaptation. Appropriate involvement and collaboration with parents and family are essential for well-functioning intervention programs. The life-long nature of autism implies that the clinician should maintain an active role in long-term treatment planning and family support. Vocational training and training for more independent living are important for adolescents with autism. Professionals should be knowledgeable about local and national resources and opportunities for family support as well as support of the individual.
Family-Based Association Study of Tryptophan-2,3 Dioxygenase(TDO2) Gene and Autism Spectrum Disorder in the Korean Population
Kim, Soon-Ae ; Park, Mi-Ra ; Cho, In-Hee ; Yoo, Hee-Jeong ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 123~129
Objectives: Autism is a complex neurodevelopmental spectrum disorder with a strong genetic component. Previous neurochemical and genetic studies have suggested the possible involvement of the serotonin system in autism. Tryptophan 2,3-dioxygenase(TDO2) is the rate-limiting enzyme in the catabolism of tryptophan, which is the precursor of serotonin synthesis. The aim of this study was to investigate the association between the TDO2 gene and autism spectrum disorders(ASD) in a Korean population. Methods: The patients were diagnosed with ASD on the basis of the DSM-IV diagnostic classification outlined in the Korean version of the Autism Diagnostic Interview-Revised and Autism Diagnostic Observation Schedule. The present study included the detection of four single nucleotide polymorphisms(SNPs) in the TDO2 gene(rs2292536, rs6856558, rs6830072, rs6830800) and the family-based association analysis of the single nucleotide polymorphisms in Korean ASD trios using a transmission disequilibrium test(TDT) and haplotype analysis. The family trios of 136 probands were included in analysis. 87.5% were male and 86.0% were diagnosed with autism. The mean age of the probands was
months(range: 26-264 months). Results: Two SNPs showed no polymorphism, and there was no significant difference in transmission in the other two SNPs. We also could not find any significant transmission in the haplotype analysis(p>.05). Conclusion: We could not find any significant statistical association between the transmission of SNPs in the TDO2 gene and ASD in a Korean population. This result may not support the possible involvement of the TDO2 gene in the development of ASD, and further exploration might be needed to investigate other plausible SNP sites.
The Relationship between Problematic Internet Use and Health Risk Behavior in Community High School Students
Kim, Yang-Suk ; Ahn, Dong-Hyun ; Kim, Yun-Yong ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 130~137
Objectives: Studies investigating problematic internet use have increased rapidly and have been focused on its causes, psychopathology, prevalence, characteristics and so on. However, there are few studies concerning the correlation between problematic internet use and youth health risk behavior. Therefore, the purpose of this study was to examine the relationship between problematic internet use and youth health risk behavior. Methods: A community sample of 632 high school students in grades 10 and 11 was collected for the survey. The sample was assessed using the Youth Risk Behavior Surveillance System(YRBSS) and Young's Diagnostic Questionnaire of Internet Addiction(YDQ). The subjects were classified into two groups: normal and problematic internet use, and the problematic internet use group was further divided into at-risk use and addiction groups. Results: There were 56 subjects(8.9%) in the internet addiction group and 56 subjects(8.9%) in the at-risk internet use group. The other 507 subjects were classified as normal. The subjects in the internet addiction group kissed more frequently and ate less fruit than those in the normal group. They also showed a relatively higher tendency to watch TV, ride in a car driven by a drunk driver and to carry a weapon than those in the normal group. There were no differences in health risk behaviors between the subjects in the internet addiction group and those in the at-risk internet use group, except for the possibility of riding in a car driven by a drunk driver. Conclusion: Unlike the normal group, there was very little difference in health risk behavior between the internet addiction group and the at-risk internet use group, which indicates that the addiction group and the at-risk internet use groups are homogenous. It is important to focus on the behavior of individuals in the at-risk group, and preventive measures should be taken in order to reduce the possibility of at-risk adolescents becoming addicted.
The Reliability and Validity of Diagnostic Interview Schedule for Children Version IV-Korean Version(DISC-IV)
Cho, Soo-Churl ; Kim, Boong-Nyun ; Kim, Jae-Won ; Kim, Hyo-Won ; Choi, Hyun-Jeong ; Jung, Sun-Woo ; Yang, Young-Hui ; Chungh, Dong-Seon ; Go, Bock-Ja ; Kim, Bong-Seog ; Shin, Min-Sup ; Yoo, Han-Ik ; Yoo, Hee-Jeong ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 138~144
Objectives: The aim of this study was to evaluate the reliability and validity of the Korean Version of the Diagnostic Interview Schedule for Children Version IV(DISC-IV), a highly structured diagnostic interview used to assess more than 30 psychiatric disorders in children and adolescents. Methods: A total of 91 study subjects, including 67 subjects who visited the child and adolescent psychiatry outpatient clinic at our institution and 24 community-based subjects, were assessed using the Korean Version of the DISC-IV. Clinical diagnosis was used as a gold standard for the examination of the validity of the DISC-IV. Forty-four of the study subjects were randomly selected for test-retest reliability measurement. Results: The validity of the Korean Version of the DISC-IV showed kappa values ranging from 0.25 to 0.40 in the clinical sample and 0.65 to 1.00 in the community sample. The sensitivities varied according to the diagnostic categories, but the specificities were excellent for all diagnostic entities. Conclusion: The Korean Version of the DISC-IV showed good reliability and validity in Korean children and adolescents. The Korean Version of the DISC-IV might be a useful tool for assessing psychiatric disorders in children and adolescents.
Chronic Aircraft Noise Exposure and Sustained Attention, Continuous Performance and Cognition in Children
Lim, Myung-Ho ; Park, Young-Hyun ; Lee, Woo-Chul ; Paik, Ki-Chung ; Kim, Hyun-Woo ; Kim, Hyun-Joo ; Rho, Sang-Chul ; Kim, Hae-Young ; Kwon, Ho-Jang ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 145~153
Objectives: This study was focused on the influence of chronic aircraft noise exposure on children's continuous performance, intelligence and reading skill. Methods: We enrolled 586 children in 4-6th grade of 7 primary schools near air base in Korea. Continuous performance was measured using the computerized ADS program. We analyzed 477-512 children on the visual continuous performance test, auditory continuous performance test, intelligence test, and reading and the vocabulary test. Intelligence was measured using vocabulary, digit span, block design, and digit symbol tests of K-WISC-III. Results: The commission error and variability deviation of auditory continuous performance test and reading test were significantly higher among children in schools with the helicopter noise and the fighting plane noise compared to children in the low noised schools. Conclusion: There was a possibility that chronic aircraft noise exposure was associated with impairment of the school performance. The result of our study also shows chronic aircraft noise was associated with reading ability.
No Association of DRD4 Exon III Polymorphism with Attention-Deficit Hyperactivity Disorder in Korean Children Population
Cho, Soo-Churl ; Park, Tae-Won ; Kim, Jae-Won ; Yoo, Hee-Jeong ; Kim, Boong-Nyun ; Shin, Min-Sup ; Hwang, Jun-Won ;
Journal of the Korean Academy of Child and Adolescent Psychiatry, volume 18, issue 2, 2007, Pages 154~161
Objectives: The aim of the current study is to test for the association of DRD4 exon III VNTR polymorphism with attention-deficit hyperactivity disorder(ADHD) in Korean children population. Methods: 113 Korean children with ADHD, 102 parents, and 133 control subjects participated with the current study. The distribution of genotypes and alleles of DRD4 exon III VNTR in children with ADHD was compared with that in control subjects. In addition, 69 children with ADHD and their parents were analyzed using the transmission disequilibrium test(TDT). Results: We could not find any significant differences in the distribution of genotypes and alleles at DRD4 exon III VNTR polymorphism between children with ADHD and control subjects. In addition, there was no preferential transmission of long allele of DRD4 exon III VNTR polymorphism. Conclusion: These results suggest that DRD4 is not associated with ADHD in Korean children population.