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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Korean Chemical Engineering Research
Journal Basic Information
Journal DOI :
The Korean Institute of Chemical Engineers
Editor in Chief :
Volume & Issues
Volume 54, Issue 4 - Aug 2016
Volume 54, Issue 3 - Jun 2016
Volume 54, Issue 2 - Apr 2016
Volume 54, Issue 1 - Feb 2016
Selecting the target year
Development and Performance Evaluation of Anti-cavitation Paint with a Lamella Glass-flake
Park, Hyeyoung ; Kim, Sung-gil ; Kim, Sang-suk ; Choi, I-chan ; Kim, Byungwoo ; Kim, Seung-jin ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 145~151
DOI : 10.9713/kcer.2016.54.2.145
In response to the cavitation caused by the partial vacuum caused by the fluid flow, a paint was developed by dispersing the lamella-shaped glass-flake in resin for anti-cavitation. This composite paint was developed by using the inorganic filler (lamella shaped glass-flake) and the NBR (Acrylonitrile-butadiene rubber) which was modified epoxy resin. Especially, the glass-flake was a thin film with a thickness of about 100~200 nm and length of about
, the aspect ratio was about 200 to 300 times that of the plate-shaped. So the paint for anti-cavitation have shown excellent performance in corrosion resistance. The results of evaluating anti-cavitation performance was below, tensile strength
or more, rupture elongation 30% or higher, abrasive speed
or less. In particular, it showed more than twice the superior performance compared to existing advanced foreign products in anti-cavitation performance evaluation.
Preparation of Photocatalysts by Hydrothermal Precipitation Method and Their Photocatalytic Performance of Brilliant Blue FCF
Kim, Seok-Hyeon ; Jeong, Sang-Gu ; Na, Seok-En ; Koo, Su-Jin ; Ju, Chang-Sik ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 152~156
DOI : 10.9713/kcer.2016.54.2.152
Experimental research on the preparation of photocatalyst for the decomposition of brilliant blue FCF (
) was performed.
and ZnO powders were prepared from titanium (IV) sulfate and zinc acetate at low reaction temperature and atmospheric pressure by hydrothermal precipitation method without calcination. In addition,
was prepared with cationic surfactant CTAB (Hexadecyltrimethyl ammonium bromide) at the same conditions. The physical properties of prepared
and ZnO, such as crystallinity, average particle size and absorbance, were investigated by XRD, Zeta-potential meter and DRS. And, the photocatalytic degradation of brilliant blue FCF has been studied in the batch reactor under UV radiation. For the photocatalysts prepared without CTAB,
has smaller particle size and larger absorbance and photocatalytic reaction rate than ZnO. And
, prepared with CTAB whose concentration is 1/10 of that of precursor, shows 15% higher than that prepared without CTAB in final photocatalytic degradation ratio of brilliant blue FCF.
Electrochemical Properties of Porous Co(OH)
Nano-flake Thin Film Prepared by Electro-deposition for Supercapacitor
Lee, Hyeon Jeong ; Jin, En Mei ; Jeong, Sang Mun ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 157~162
DOI : 10.9713/kcer.2016.54.2.157
nano-flake thin films were prepared by a potential-controlled electro-deposition technique at various deposition voltage (-0.75, -1.0, -1.2, and -1.4 V) on Ti-mesh substrates for supercapacitor application. The potential of electrode was controlled to regulate the film thickness and the amount of
nano-flake on the titanium substrate. The film thickness was shown to reach the maximum value of
at -1.4 V of electrode potential, where 17.2 g of
was deposited on the substrate. The specific discharge capacitances were measured to be 226, 370, 720, and
in the 1st cycle corresponding to the films which were formed at -0.75, -1.0, -1.2, and -1.4 V of electrode potentials, respectively. Then the discharge capacities were decreased to be 206, 349, 586 and
, where the persistency rates were 91, 94, 81, and 86%, respectively.
Effect of the Types of Silane Coupling Agents on the Properties of the Hydrophilic Coating Films
Lee, Byoung-Hwa ; Kim, Eun-Ki ; Lee, Sul ; Lim, Hyung-Jun ; Lee, In-Pyo ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 163~170
DOI : 10.9713/kcer.2016.54.2.163
In order to improve the hydrophilic property of polymer films, coating solutions which showed a good hydrophilic property, were prepared by the sol-gel method. The coating solutions were prepared by adding different types of silane coupling agents (aminosilane, epoxysilane and acrylsilane) to a colloidal silica (15 nm diameter). The solutions prepared by adding aminosilane resulted in gels which could not be used as coating solutions. On the other hand, the coating solutions prepared by the addition of epoxysilane showed contact angles of
and good hydrophilic property at R=0.10~0.15 (R=silane coupling agent/colloidal silica weight ratio). In addition, the coating solutions prepared by the addition of acrylsilane at R=0.03~0.07, exhibited contact angles of
, which means better hydrophilic property than aminosilane or epoxysilane.
Effect of Fabrication Method of Cathode on OCV in Enzyme Fuel Cells
Lee, Se-Hoon ; Kim, Young-Sook ; Chu, Cheun-Ho ; Na, Il-Chai ; Lee, Jung-Hoon ; Park, Kwon-Pil ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 171~174
DOI : 10.9713/kcer.2016.54.2.171
Enzyme fuel cells were composed of enzyme cathode and PEMFC anode. Enzyme cathode was fabricated by compression of a mixture of graphite particle, laccase as a enzyme and ABTS as a redox mediator, and then coated with Nafion ionomer. Open circuit voltage (OCV) were measured with variation of cathode manufacture factors, to find optimum condition of enzyme cathode. Optimum pressure was 4.0 bar for enzyme cathode pressing process. Highest OCV was obtained at 95% graphite composition in enzyme cathodee. Optimum glucose concentration was 0.4 mol/l in cathode substrate solution.
Synthesis and Ozone Resistance Characteristic of Fluorine-containing modified Polyurea
Kim, Sung Rae ; Park, Ji Yong ; Lee, Jong Dae ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 175~180
DOI : 10.9713/kcer.2016.54.2.175
The fluorine-containing modified polyurea was synthesized using the PTPE-diol to improve the ozone-resistance. Three types (PFDIA-10C, PFDIA-20C, PFDIA-30C) of the modified polyurea containing the fluorine content from 10 wt% to 30 wt% were prepared. After ozone treatment on the prepared films, the weight loss of film was investigated and analyzed the film properties such as hardness, wear resistance, tensile stress, elongation, etc. Also, the film surfaces were observed by the optical microscopy after ozone-resistance tests at 10 ppm for 336 h. It was shown that the defects such as the cracking, the bleaching and the mass loss were reduced and the ozone-resistance of films were improved when the contents of PFPE-diol are more than 20 wt%. It was found that the intensity of O-H peak in PFDIA compounds confirmed by FT-IR was decreased as fluorine contents were increasing.
Characteristics of Proton Exchange Membrane Fuel Cells(PEMFC) Membrane and Electrode Assembly(MEA) Using Sulfonated Poly(ether ether ketone) Membrane
Lee, Hye-Ri ; Lee, Se-Hoon ; Hwang, Byung-Chan ; Na, Il-Chai ; Lee, Jung-Hun ; Oh, Sung-June ; Park, Kwon-Pil ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 181~186
DOI : 10.9713/kcer.2016.54.2.181
Recently, there are many efforts focused on development of more economical non-fluorinated membranes for use in PEMFCs (Proton Exchange Membrane Fuel Cells). In this study, characteristics of sulfonated Poly(ether ether ketone) (sPEEK) were compared according to degrees of sulfonation (DS), relative humidity, cell temperatures at PEMFC operation condition. I-V polarization curve, hydrogen crossover, electrochemical surface area, membrane resistance and charge transfer resistance were measured. sPEEK membrane showed high performance at high DS, high temperature and high relative humidity, in particular, performance of sPEEK membrane decreased largely due to low ionic conductivity at low DS and low relative humidity.
Odor Modeling of trimethyl amine in Gumi National Industrial Complex
Lee, Eun Ju ; Khan, Mousumee ; Lim, Kwang-Hee ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 187~199
DOI : 10.9713/kcer.2016.54.2.187
In this study CALPUFF modeling was performed to predict a contribution of a separate single point pollutant source as well as of total point pollutant sources of major synthetic fiber manufacturers in Gumi national industrial complex to atmospheric trimethylamine concentration of the same area. In addition, a contribution of the separate single point pollution source to the atmospheric trimethylamine concentration of the same area was estimated relatively to the total point pollutant sources. As a result of the CALPUFF modeling, the maximum atmospheric concentration of trimethylamine in Gumi national industrial complex was appeared upon improving T company emission facility frequently in complex 3 in winter (January) and spring (April) while frequently in complex 1 in summer (July) and autumn (October). Besides, the predicted range of the maximum atmospheric concentration of trimethylamine in complex 1 was improved upon improving its emission facility. However, even though in complex 3 the upper bound of the predicted maximum atmospheric concentrations of trimethylamine was increased upon improving T company emission facility, the predicted value of their second upper bound below the upper bound was very similar to the upper bound of measured atmospheric trimethylamine concentrations in Gumi prior to improving its emission facility. Thus, the effect of improving T company emission facility was estimated huge in complex 1 while it was trivial in complex 3. These maximum concentrations of trimethylamine predicted to estimate the expected contribution of total point pollutant sources by CALPUFF modeling showed the similar values to those measured in the region of Gumi. Therefore, the expected contribution of total point pollutant sources to atmospheric trimethylamine concentration in the area of Gumi was validated.
Preparation of Chitosan-Gold and Chitosan-Silver Nanodrug Carrier Using QDs
Lee, Yong-Choon ; Kang, Ik-Joong ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 200~205
DOI : 10.9713/kcer.2016.54.2.200
A drug transport carrier could be used for safe send of drugs to the affected region in a human body. The chitosan is adequate for the drug delivery carrier because of adaptable to living body. The gold, a metallic nanoparticles, tends to form a nano complex at rapidly when it combined with chitosan because of its negative charge. having energy from the other, outer gold nano-complex make heat due to its property to release the contained drugs to the target area. Silver could be also formed an useful biocompatible nano-composites with chitosan which should be used as an useful drug transfer carrier because its special ability to protect microbial contamination. Being one of the oxidized nano metals,
is nontoxic and has been used for its magnetic characteristics. In this study, the control of catalyst, reducing agent, and solvent amount. The chitosan-
-gold & silver nanoshell have been changed to form about 100 nm size by ionic bond between the amine group, an end group of chitosan, and the metal. It was observed the change in order to seek for its optimum reaction condition as a drug transfer carrier.
Phase Equilibria Measurement of Binary Mixture for the Propoxylated Neopentyl Glycol Diacrylate in Supercritical Carbon Dioxide
Byun, Hun-Soo ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 206~212
DOI : 10.9713/kcer.2016.54.2.206
Experimental data are reported on the phase equilibrium of propoxylated neopentyl glycol diacrylate in supercritical carbon dioxide. Phase equilibria data were measured in static method at a temperature of (313.2, 333.2, 353.2, 373.2 and 393.2) K and at pressures up to 27.82 MPa. At a constant pressure, the solubility of propoxylated neopentyl glycol diacrylate for the (carbon dioxide + propoxylated neopentyl glycol diacrylate) system increases as temperature increases. The (carbon dioxide + propoxylated neopentyl glycol diacrylate) system exhibits type-I phase behavior. The experimental result for the (carbon dioxide + propoxylated neopentyl glycol diacrylate) system is correlated with Peng-Robinson equation of state using mixing rule. The critical property of propoxylated neopentyl glycol diacrylate is predicted with Joback and Lyderson method.
Solubility of Hydrogen Sulfide and Methane in Ionic Liquids: 1-Ethy-3-methylimidazolium Trifluoromethanesulfonate and 1-Butyl-1-methylpyrrolidinium Trifluoromethanesulfonate
Lee, Byung-Chul ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 213~222
DOI : 10.9713/kcer.2016.54.2.213
Solubility data of hydrogen sulfide (
) and methane (
) in two kinds of ionic liquids with the same anion: 1-ethyl-3-methylimidazolium trifluoromethanesulfonate ([emim][TfO]) and 1-butyl-1-methylpyrrolidinium trifluoromethanesulfonate ([bmpyr][TfO]) are presented at pressures up to about 30 MPa and at temperatures between 303 K and 343 K. The gas solubilities in ionic liquids were determined by measuring the bubble point pressures of the gas + ionic liquid mixtures with various compositions at different temperatures using a high-pressure equilibrium apparatus equipped with a variable-volume view cell. The
solubilities in ionic liquid increased with the increase of pressure and decreased with the increase of temperature. On the other hand, the
solubilities in ionic liquid increased significantly with the increase of pressure, but there was little effect of temperature on the
solubility. For the ionic liquds [emim][TfO] and [bmpyr][TfO] with the same anion, the solubility of
as a molality basis was substantially similar, regardless of the temperature and pressure conditions as a molar concentration basis. Comparing the solubilities of
in the ionic liquid [emim][TfO], the solubilities of
were much greater than those of
. For the same type of ionic liquid, the solubility data of
obtained in this study were compared to the solubility data of
from the literature. When compared at the same pressure and temperature conditions, the
solubility was in between the solubility of
Simple Fabrication of Adipocyte Cell Chip Using Micropatterning
Kim, Gi Yong ; Jeong, Heon-Ho ; Lee, Chang-Soo ; Roh, Changhyun ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 223~228
DOI : 10.9713/kcer.2016.54.2.223
In this study, we described a simple and facile method to generate uniform microwells poly(dimethyl siloxane) (PDMS) microstamps through micro-molding for efficient, rapid and reliable cell patterning of adipocyte differentiation. In contrast to the conventional methods, the microstamp technologies are low expensive, non-toxic, and using a small amount of solution. Recently, Orlistat known as tetrahydrolipstatin is a prescription drug designed to treat obesity which is used to aid in weight loss and help to reduce overweight obesity. Here, 3T3-L1 cells were treated under various concentration manners of Orlistat
. and it was confirmed maximum 26.5% inhibition activity compared to control. Thus, we elucidated this platform can be used for the real-time analyzing of cell proliferation, adipocyte differentiation for evaluation of anti-obesity agents on cell chip. Furthermore, we except that this platform technology designed here might be readily be expanded to discover a wider variety of anti-obesity agents.
Ultrasound-Assisted Liquid-Liquid Extraction for Recovery of Paclitaxel from Plant Cell Cultures
Ha, Geon-Soo ; Kim, Jin-Hyun ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 229~233
DOI : 10.9713/kcer.2016.54.2.229
In this study, an efficient ultrasound-assisted liquid-liquid extraction process was developed for recovering of paclitaxel from plant cell cultures. The optimal ultrasonic power and operating time were 250 W and 15 min at fixed ratio of bottom phase, methylene chloride to top phase, MeOH (25%, v/v). Under the optimal conditions developed in the present method, most of the paclitaxel (~92%) was recovered from crude extract by a single extraction step. Due to the synergistic effect of ultrasound by the addition of inorganic salt, an appropriate inorganic salt concentration and the ultrasonic power were found to be required for the effective recovery of paclitaxel using ultrasound-assisted liquid-liquid extraction.
Comparative Characterization of AFC Precipitated Using Vacuum Drying, Dilution Precipitation and Spray Drying
Kwon, Ho Jung ; Choi, Ho Kyung ; Jo, Wan Taek ; Kim, Sang Do ; Yoo, Ji Ho ; Chun, Dong Hyuk ; Rhim, Young Joon ; Lim, Jeong Hwan ; Lee, Si Hyun ; Rhee, Young Woo ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 234~238
DOI : 10.9713/kcer.2016.54.2.234
Solid ash-free coal (AFC) samples recovered from solvent-extracted solution by vacuum drying, dilution precipitation and spray drying methods were compared in terms of physical properties and chemical structure. AFC was prepared by using Kideco coal (Indonesian sub-bituminous coal) and polar N-methyl-2-pyrrolidone (NMP) solvent as raw materials. The physical properties of the AFCs were characterized with proximate, ultimate, and calorific value analysis. In analyzing the chemical structure, FTIR and NMR were used. the proximate analysis showed much reduced ash in the AFCs compared to parent raw coal. The FTIR result showed that the extraction solvent was not fully removed from the AFC prepared by vacuum drying. However, the solvent was not detected in the AFC recovered by using dilution precipitation. Dilution precipitation has advantages over the other two methods, since it can be done at relatively low temperature and separate ash-free coal from extraction solvent more effectively.
Activated Carbon Adsorption Characteristics of Multi-component Volatile Organic compounds in a Fixed Bed Adsorption Bed
Cho, Jong Hoon ; Lee, Sihyun ; Rhee, Young Woo ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 239~247
DOI : 10.9713/kcer.2016.54.2.239
This study aims to examine absorption characteristics of toluene, isopropyl alcohol (IPA), ethyl acetate (EA), and ternary-compounds, all of which are widely used in industrial processes, by means of four types of commercial activated carbon substances. It turned out that among the three types of volatile organic compounds, the breakthrough point of activated carbon and that of IPA, whose affinity was the lowest, were the lowest, and then that of EA and that of toluene in the order. With the breakthrough point of IPA, which was the shortest, as the standard, changes in the breakthrough points of unary-compounds, binary-compounds, and ternary-compounds were examined. As a result, it turned out that the larger the number of elements, the lower the breakthrough point. This resulted from competitive adsorption, that is, substitution of substances with a low level of affinity with those with a high level of affinity. Hence, the adsorption of toluene-IPA-EA and ternary-compounds require a design of the activated carbon bed based on the breakthrough of IPA, and in the design of activated carbon beds in actual industries as well, a substance whose level of affinity is the lowest needs to be the standard.
Simulation Analysis of Sludge Disposal and Volatile Fatty Acids Production from Gravity Pressure Reactor via Wet Air Oxidation
Park, Gwon Woo ; Seo, Tae Wan ; Lee, Hong-Cheol ; Hwang, In-Ju ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 248~254
DOI : 10.9713/kcer.2016.54.2.248
Efficacious wastewater treatment is essential for increasing sewage sludge volume and implementing strict environmental regulations. The operation cost of sludge treatment amounts up to 50% of the total costs for wastewater treatment plants, therefore, an economical sludge destruction method is crucially needed. Amid several destruction methods, wet air oxidation (WAO) can efficiently treat wastewater containing organic pollutants. It can be used not only for sludge destruction but also for useful by-product production. Volatile fatty acids (VFAs), one of many byproducts, is considered to be an important precursor of biofuel and chemical materials. Its high reaction condition has instituted the study of gravity pressure reactor (GPR) for an economical process of WAO to reduce operation cost. Simulation of subcritical condition was conducted using Aspen Plus with predictive Soave-Redlich-Kwong (PSRK) equation of state. Conjointly, simulation analysis for GPR depth, oxidizer type, sludge flow rate and oxidizer injection position was carried out. At GPR depth of 1000m and flow rate of 2 ton/h, the conversion and yield of VFAs were 92.02% and 0.17g/g, respectively.
Equilibrium, Kinetic and Thermodynamic Parameter Studies on Adsorption of Acid Yellow 14 Using Activated Carbon
Lee, Jong Jib ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 255~261
DOI : 10.9713/kcer.2016.54.2.255
Adsorption experiments of Acid Yellow 14 dye using activated carbon were carried out as function of adsorbent dose, pH, initial concentration, contact time and temperature. The equilibrium adsorption data were analyzed by Langmuir, Freundlich and Temkin isotherm model. The experimental data were best represented by Freundlich isotherm model. Base on the estimated Freundlich constant (1/n=0.129~0.212) and Langmuir separation factor (
), this process could be employed as effective treatment method. The heat of adsorption of Temkin isotherm model was 5.101~9.164 J/mol indicated that the adsorption process followed a physical adsorption. Adsorption kinetics experimental data were modeled using the pseudo-first-order and pseudo-second-order kinetic equation. It was shown that pseudo-second-order kinetic equation could best describe the adsorption kinetics. Base on the negative Gibbs free energy (-4.81~-10.33 kJ/mol) and positive enthalpy (+78.59 kJ/mol) indicate that the adsorption is spontaneous and endothermic process.
Carbon Nanotube-based Nanohybrid Materials as Counter Electrode for Highly Efficient Dye-sensitized Solar Cells
Kim, Ji-Soo ; Sim, Eun-Ju ; Dao, Van-Duong ; Choi, Ho-Suk ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 262~267
DOI : 10.9713/kcer.2016.54.2.262
In this study, we present an excellent approach for easily and uniformly immobilizing Pt, Au and bimetallic PtAu nanoparticles (NPs) on a multi-walled carbon nanotube (MWNT)-coated layer through dry plasma reduction. The NPs are stably and uniformly immobilized on the surface of MWNTs and the nanohybrid materials are applied to counter electrode (CE) of dye-sensitized solar cells (DSCs). The electrochemical properties of CEs are examined through cyclic voltammogram, electrochemical impedance spectroscopy, and Tafel measurements. As a result, both electrochemical catalytic activity and electrical conductivity are highest for PtAu/MWNT electrode. The DSC employing PtAu/MWNT CE exhibits power conversion efficiency of 7.9%. The efficiency is better than those of devices with MWNT (2.6%), AuNP/MWNT (2.7%) and PtNP/MWNT (7.5%) CEs.
The Preparation and Property of Carbon Foams from Carbon Black Embedded Pitch Using PU Template
Lee, Sangmin ; Kim, Ji-Hyun ; Jeong, Euigyung ; Lee, Young-Seak ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 268~273
DOI : 10.9713/kcer.2016.54.2.268
To improve mechanical strength of carbon foams, the carbon black (CB) added carbon foams were fabricated by impregnating different contents of carbon black (CB) and mesophase pitch using polyvinyl alcohol (PVA) solution into polyurethane foam and being followed by heat treatment. The cell wall-thicknesses of carbon foams were controlled by adding amounts of CB, and it was confirmed that the compressive strength of carbon foams was increased as increasing cell wall-thickness. The compressive strength had the highest value of
with the highest bulk density of
when adding 5 wt% CB in carbon foam. However, the thermal conductivity was decreased by adding CB in carbon foam. The results indicated that the thermal conductivities of carbon foams were reduced by increased interlayer spacing (
) with the addition of CB in carbon foams.
Evaluation of green light Emitting diode with p-type GaN interlayer
Kim, Eunjin ; Kim, Jimin ; Jang, Soohwan ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 274~277
DOI : 10.9713/kcer.2016.54.2.274
Effects of interlayer insertion between multi-quantum well and electron blocking layer of green light emitting diode on diode performances were studied by device simulation. Dependence of Mg doping depth on characteristics of current-voltage, emitting wavelength, leakage current, and external quantum efficiency was investigated, and the optimum diode structure was presented. Device structures with interlayers doped in entire region and up to 30 nm showed remarkable reduced leakage current and effectively relieved efficiency droop which is one of the biggest challenges in green light emitting diode. Furthermore, the most improved characteristics in current-voltage and electroluminescence was obtained by the latter structure.
Decreasing Particle Size of Paclitaxel Using Polymer in Fractional Precipitation Process
Kim, Min Jae ; Kim, Jin-Hyun ;
Korean Chemical Engineering Research, volume 54, issue 2, 2016, Pages 278~283
DOI : 10.9713/kcer.2016.54.2.278
In this study, we have for the first time applied fractional precipitation with hydrophilic polymer in order to decrease the particle size of the anticancer agent paclitaxel from plant cell cultures. When compared with the case where no hydrophilic polymer was employed, the addition of hydrophilic polymer in fractional precipitation resulted in a decrease in the size of the paclitaxel precipitate. Among the polymers used, HPMC 2910 was the most effective for inhibition of precipitate growth. A polymer concentration of 0.2% (w/v) obtained the smallest particle size. The particle size was reduced by ~35% compared to control. In addition, the precipitate size was inversely correlated with the absolute value of the zeta potential.