Go to the main menu
Skip to content
Go to bottom
REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Korean Journal of Acupuncture
Journal Basic Information
Journal DOI :
Society for Meridian and Acupoint
Editor in Chief :
Volume & Issues
Volume 17, Issue 1 - Mar 2000
Selecting the target year
Effects of Gamdutang Aqua-acupuncture Solution on Tumor Cell Lines in vitro
Han Sang-Hoon ; Park In-Kyu ; Lim Chang-Soo ; Moon Jin-Young ; Lim Jong-Kook ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 1~10
Gamdutang aqua-acupuncture solution(GAS) and Gamdutang water-extracted solution(GWS) were prepared and tested for potential antitumor activites. It was shown to possess considerable toxicity toward various tumor cell lines. Concentration of
of GAS resulted in more than 70% inhibition of growth in Ehrlich ascites tumor cells(EATC), hepa1c1c7 and A549. GAS at the concentration of
revealed that more than 60% inhibition in HeLa. GWS showed more than 50% in hibition of growth with EATC, HeLa at the concentration of
. Toxicity assay with GWS in hepa1c1c7 and A549 revealed that more than 80% inhibition in growth at the concentration of
. In morphological study, the number of cells were decreased, and the shape of cells was round-form. Most of cells in detached in EATC, Hepa1c1c7, HeLa, and A549 with GAS. These results suggest that GAS has antitumor activity in vitro.
Effect of Aqua-acupuncture Solution of Medicinal Plants on Induction of Anticarcinogenic Phase II Enzymes
Lim Jong-Kook ; Moon Jin-Young ; Cho Kyoung-Hee ; Shon Yun-Hee ; Nam Kyung-Soo ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 11~17
Induction of phase II enzymes such as quinone reductase (QR) or glutathione S-transferase (GST) is considered a major mechanism of protection against initiation of carcingenesis. The induction of detoxification enzymes and glutathione were studied with Lonicerae Flos aqua-acupuncture solution (LFAS), Angelicae gigantis Radix aqua-acupuncture solution (AGRAS), and Gamdutang aqua-acupunture solution (GAS) in murine hepatoma cells grown in microtiter plate wells. LFAS, AGRAS and GAS were potent inducers of QR activity. LFAS was induced about 2.6-fold at concentration of
. AGRAS and GAS were also induced about 2.6-, 1.8-fold at concentration of
, respectively. In addition, GST activity was increased with LFAS, AGRAS, and GAS. GSH levels were increased about 2-fold with LFAS at concentration of
, 1.3-fold with AGRAS at concentration of
, and 1.2-fold with GAS at concentration of
. These results suggested that LFAS, AGRAS, and GAS may act as blocking agents against carcinogenesis by induction of phase II marker enzymes.
Effects of Acupuncture at Taekjung and Ungyo
Bloodletting on Liver Function
Lim Kwan-Il ; Lee Joon-Moo ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 19~31
Effects of acupuncture at Taekjung and Ungyo(
) bloodletting on serum glutamic oxaloacetic transaminase (GOT) activity, glutamic pyruvic transaminase activity(GPT), total Protein, Albumin, Alkalin Phosphatase(ALP),
-GT, lactic dehydrogenase (LDH), total cholesterol and triglyceride were determined. 1) In the Ungyo bloodletting group, GOT, GPT, ALP,
-GT and LDH activity showed a tendency to decrease compared to those of
only group and Taekjung acupuncture group. 2) Serum albumin content showed a tendency decrease by treatment of
and to increase by treatment of Ungyo bloodletting. 3) The values of serum total protein, total cholesterol and triglyceride showed no significant difference among all the treatment groups. 4) All the biological values showed no significant difference between the
only group and Taekjung acupuncture group except the values of albumin. Results from this study indicate that the Ungyo bloodletting showed the possibility of liver function recovery in liver-harmed rats by
The Effects of Moxi tar on iNOS Synthase in RAW 264.7 Cell
Ahn Sung-Hun ; Koo Sung-Tae ; Do Jin-Woo ; Kim Jong-Sung ; Kim Kwang-Soo ; Yang Beom-Sik ; Kim Kyung-Sik ; Sohn In-Chul ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 33~46
This study was produced to examine the effects of moxibution that had been played a role of traditional oriental medical treatment on disease. We used LPS and INF-gamma in RAW 264.7 cell line to produce Nitric Oxide(NO). And results was that Moxi tar decreased NO in activated RAW 264.7 cell by LPS and INF-gamma significantly, which was decreasing Nitric Oxide Synthase. So we proposed that Moxi tar had anti-inflammation and anti-cytotoxity in RAW 264.7 cell by decreasing Nitric Oxide Synthase.
The Effects on the Thermal Changes of Five-Shu-Points(五輸穴) and Yonghyang
,迎香) of the Large Intestine Meridian with the Rotated Acupuncture-Bu-Xie(捻轉補瀉) on the Hapkok
,合谷), Using the D.I.T.I.
Song Beom-Yong ; Kim Kyung-Sik ; Sohn In-Chul ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 47~65
The meridian, the meridian point and the Acupuncture-Bu-Xie(鍼灸補瀉) of oriental medicine are very important in the Department of Acupuncture and Moxibustion. Until now it has been confused at the practical use, and it showed up many transformation to the ages and many scholars. And then, I made a study of effects on the thermal changes of Sangyang(
,迎香) following acupuncture on the Hapkok with the Rotated Acupuncture-Bu-Xie(捻轉補瀉) stimulation. This study researched into clinical statistics for 140 men who are in good health, and they are studying oriental medicine at Woosuk university in Korea. This study was covered a period of 3 months form June, 1999 to August, 1999. The objective was divided into seven groups, those are the control group(CON, N=20), the acupuncture stimulation group with non-rotation on Hapkok of left hand(A-I, N=20), the acupuncture stimulation group with non-rotation on non-meridian point(NA) of left hand(A-II, N=20), the acupuncture stimulation group with Bu-rotation(捻轉補法) on Hapkok of left hand(B-I, N=20), the acupuncture stimulation group with Bu-rotation on non-meridian point(NA) of left hand(B-II, N=20), the acupuncture stimulation group with Xie-rotation(捻轉瀉法) on Hapkok of left hand(C-I, N=20), and the acupuncture stimulation group with Xie-rotation on non-meridian point of left hand(C-II, N=20). The first, I took a picture for 140 men with the Digital infrared thermal image(D.I.T.I.). After 10 minutes, I took a second picture for each group following experimental methods, those were followed acupuncture on the Hapkok and the non-meridian point with the retentive and Rotated Acupuncture-Bu-Xie stimulation. The results are summarized as follows : 1. The thermal changes of the area which is a meridian point in the Large Intestine Meridian of the acupuncture stimulation group on Hapkok different from the control groups with significantly change. 2.The thermal changes of the area which is a meridian point in the Large Intestine Meridian of acupuncture stimulation groups on non-meridian point was not significantly different from the control group. 3. The thermal changes of the area which is a meridian point in the Large Intestine Meridian of the acupuncture stimulation group with Bu-rotation on Hapkok different from the control group with significant increase. 4. The thermal changes of the area which is a meridian point in the Large Intestine Meridian of acupuncture stimulation group with Bu-rotation on non-meridian point was not significantly different from the control group. 5. The thermal changes of the area which is a meridian point in the Large Intestine Meridian of the acupuncture stimulation group with Xie-rotation on Hapkok different from the control group with significant decrease and increase following the decreasing or increasing temperature class, and the increasing temperature class of the acupuncture stimulation group with Xie-rotation on Hapkok significantly different from the acupuncture stimulation group with Bu-rotation on Hapkok. 6. The thermal changes of the area which is a meridian point in the Large Intestine Meridian of acupuncture stimulation group with Xie-rotation on non-meridian point was not significantly different from the control group. As a conclusion, I could think that the acupuncture stimulation with Bu-rotation or Xie-rotation on Hapkok affected the thermal change of the area which is a meridian point in the Large Intestine Meridian. And then I could relate these results with the existence of the meridian and meridian point, and with the Rotated Acupuncture-Bu-Xie theory of oriental medicine.
Effects of Radix Stemonae on the Airway Smooth Muscle
Kim Sung-Kyu ; Woo Won-Hong ; Ryu Do-Gon ; Han Jong-Hyun ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 67~73
The purpose of the present study is to determine the effect of Radix Stemonae on histamine induced tracheal smooth muscle contraction in guinea pigs. Guinea pig(500g, male) were killed by
exposure and a segment (8-10mm) of the thoracic trachea from guinea pig was cut into equal segments and mounted 'in pairs' in a tissue bath. Contractile force was measured with force displacement transducers under 0.5g loading tension. The dose of histamine (His) which evoked 50% of maximal response (
) was obtained from cumulative dose response curves for histamine (
). Contractions evoked by His (
) were inhibited significantly by Radix Stemonae. In guinea pig tracheal smooth muscle, the mean percent inhibition of histamine induced contraction was 87.4% (p<0.01) after
Radix Stemonae. Following treatment with propranolol, the mean percent inhibition caused by
Radix Stemonae fell to 16.2% in guinea pig induced by histamine contraction. Indomethacin and methylene blue(
) did not significantly alter the inhibitory effect of Radix Stemonae. These results indicate that Radix Stemonae can relax histamine induced contraction of guinea pig tracheal smooth muscle, and that this inhibition involves sympathetic effects.
Effects of Fructus Aristolochiae on the Vascular Smooth Muscle
Kim Hyung-Chang ; Ryu Do-Gon ; Han Jong-Hyun ; Lee Ho-Sub ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 75~80
Fructus Aristolochiae has been used in Korea for many centuries as a treatment for various disease.The purpose of the present study is to determine the effect of Fructus Aristolochiae on norepinephrine(NE) induced blood vessel contraction in rabbits. Rabbit(2 kg, male) were killed by
exposure and a segment (8-10mm) of each rabbit was cut into equal segments and mounted in a tissue bath. Contractile force was measured with force displacement transducers under 2-3 g loading tension. The dose of norepinephrine(NE) which evoked 50% of maximal response (
) was obtained from cumulative dose response curves for NE (
). Contractions evoked by NE (
) were inhibited significantly by Fructus Aristolochiae in abdominal aorta and femoral artery. Fructus Aristolochiae inhibited the relaxation pretreated propranolol and L-NNA in femoral artery. But Fructus Aristolochiae did not effect the relaxation pretreated ODQ in femoral artery and abdominal aorta. These results indicate that Fructus Aristolochiae can relax NE induced contraction of rabbit blood vessel selectively, and that this relaxation relates to nitric oxide synthesis and sympathetic action.
Central Localization of the Neurons Projecting to the Urinary Bladder Meridian
Kim Jeong-Yun ; Jun Hong-Jae ; Lee Sang-Ryoung ; Lee Chang-Hyun ; Chung Ok-Bong ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 81~100
Localization of the Neurons Projecting to the Gallbladder Meridian
Ryuk Sang-Won ; Lee Kwang-Gyu ; Lee Sang-Ryoung ; Kim Jum-Young ; Lee Chang-Hyun ; Lee Bong-Hee ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 101~121
The purpose of this morphological studies was to investigate the relation to the meridian, acupoint and nerve. The common locations of the spinal cord and brain projecting to the the gallbladder, GB34 and common peroneal nerve were observed following injection of transsynaptic neurotropic virus, pseudorabies virus(PRV), into the gallbladder, GB34 and common peroneal nerve of the rabbit. After survival times of 96 hours following injection of PRV, the thirty rabbits were perfused, and their spinal cord and brain were frozen sectioned(
). These sections were stained by PRV immunohistochemical staining method, and observed with light microscope. The results were as follows: 1. In spinal cord, PRV labeled neurons projecting to the gallbladder, GB34 and common peroneal nerve were founded in thoracic, lumbar and sacral spinal segments. Densely labeled areas of each spinal cord segment were founded in lamina V, VII, X, intermediolateral nucleus and dorsal nucleus. 2. In medulla oblongata, The PRV labeled neurons projecting to the gallbladder, GB34 and common peroneal nerve were founded in the A1 noradrenalin cells/C1 adrenalin cells/caudoventrolateral reticular nucleus, rostroventrolateral reticular nucleus, medullary reticular nucleus, dorsal motor nucleus of vagus nerve, nucleus tractus solitarius, raphe obscurus nucleus, raphe pallidus nucleus, raphe magnus nucleus, gigantocellular nucleus, lateral paragigantocellular nucleus, principal sensory trigeminal nucleus and spinal trigeminal nucleus. 3. In Pons, PRV labeled neurons were parabrachial nucleus, Kolliker-Fuse nucleus and cochlear nucleus. 4. In midbrain, PRV labeled neurons were founded in central gray matter and substantia nigra. 5. In diencephalon, PRV labeled neurons were founded in lateral hypothalamic nucleus, suprachiasmatic nucleus and paraventricular hypothalamic nucleus. 6. In cerebral cortex, PRV labeled neuron were founded in hind limb area.This results suggest that PRV labeled common areas of the spinal cord projecting to the gallbladder, GB34 and common peroneal nerve may be first-order neurons related to the somatic sensory, viscero-somatic sensory and symapathetic preganglionic neurons, and PRV labeled common area of the brain may be first, second and third-order neurons response to the movement of smooth muscle in gallbladder and blood vessels.These PRV labeled neurons may be central autonomic center related to the integration and modulation of reflex control linked to the sensory system monitoring the internal environment, including both visceral sensation and various chemical and physical qualities of the bloodstream. The present morphological results provide that gallbladder meridian and acupoint may be related to the central autonomic pathways.
Study for Understanding the Special Character and the Tendency of Movement Change in Twelve Meridians
Shuk Dong-Yun ; Choi Chan-Hun ; Jang Kyeong-Seon ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 123~140
The purpose of this study is to understand the special character and the tendency of the movement change that 12 meridians possess. We studied about the incidental and fundamental rule of the six atmospheric influence that was presented by Pyobonjoong(the incidental, fundamental, intermediate) theory, and the Hwang won-uh's the Six Channel activity of the Qi theory that presented movement form of the meridian through the six atmospheric influence. Then we found the following substances. The Pyobonjoong(the incidental, fundamental, intermediate) theory is applicable to understand the special character and the tendency of the movement change that Meridians possess. But, because the Pyobonjoong(the incidental, fundamental, intermediate) theory can't classify the characteristic difference of the hand and foot meridians, then the principle that can devide the meridians of the hand and foot, must be supplied. The Jungwha(right changing)-Daewha(opposite changing) theory is able to concretely classify the special character of the hand and foot six meridians. And Hwang's Shawha(superintending change)-Jongwha(following change) theory that is base on Jungwha(right changing)-Daewha(opposite changing) theory, is able to classify the special character of the hand and foot six meridians, too. If the concept of the Meridians is understood by the Shawha(superintending change)-Jongwha(following change) theory, the special character of the hand and foot six meridians could be concretely classified and then the meridian of the Bowels and the six atmospheric influence corresponded to the meridians could be expansively explained as the point that take charge and control these special Qi in the human body The Bon-Qi(fundamental Qi) act on the special character of Shawha(superintending change) six meridians and the tendency of the movement change is cause by the insufficiency and excessiveness of the Bon-Qi(fundamental Qi). The Qi of the Shawha(superintending change) meridians act on the special character of Jongwha(following change) six meridians and the tendency of the movement change is cause by the exuberance of Yang and the deficiency of Yang.
Pain and Muscle Elasticity for Deficiency-Excessiveness Discussed by the View of Oriental and Western Medicine
Lee Dong-Kyu ; Seo Hyung-Joo ; Na Chang-Su ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 141~156
Prognosis in oriental medicine gathers information by four examination methods. It provides important information to understand the degree of deficiency - excessiveness of a patient to treat properly. To generalize the degree of deficiency - excessiveness can be found by seeing the patient's muscle response and pain perception to the palpitations.The theoretical basis to generalize deficiency - excessiveness, oriental and western medical understanding of pain perception and the elasticity of muscle were discussed.The usual symptoms for the excessiveness could include Pain (dislikeness to the palpitation), Stiffness of nape and limbs, Contracture of the limbs, Clonic convulsion and Fast pain. The symptoms for the deficiency could include Pain (likeness to the palpitation, Gastrocnemius muscle spasm, Flaccid paralysis of limbs and Slow pain. More theoretical bases for generalization of deficiency - excessiveness are needed along with the simplifying the complex clinical symptoms. In this way, we can discuss about deficiency - excessiveness with the regard to western medicine to help its generalization.
Relationship of Front Points' Location and Function to Response Zone
Lee Dong-Kyu ; Na Chang-Su ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 157~171
Front Points are told to be deeply related with viscera and bowels in oriental medicine. Since the Front Points are treated as response zone, it can be used for the diagnosis and treatment of disease in viscera and bowels. The location of Front Points are very similar to the several response zones in western medicine. Diagnostic aspect of Front Points to several response zones were discussed in here based on many thesis and reported laboratorial experiments. Front Points are located in the same latitude of viscera and bowels. So, diagnosis result in Front Points represent condition of each organs. Palpitation of the Front Points can make diagnosis of body surface and the organ beneath the body surface. Such use of Front Points for diagnosis can used as the treatment points also. Only three Front Points (LU-1, LI-14, GB-24) in lung, liver and gall bladder meridian are located on its meridian. The Front Points of Stomach (CV-12) cross its meridian or closely located to it. Unlike to those four Front Points that are matched to its meridian, other eight Front Points do not located or cross its meridian at all. It seems that the location of Front Points are decided by the location of organs and the conditions at a certain organ do not delivered by the meridians but delivered by main collaterals, tertiary collaterals and superficial collaterals instead. Among visceral response zones, Five Front Points (CV-3, CV-4, CV-12, LI-14, GB-25) are exactly matched to Head's response zone and other Front Points are closely matched to the Head's response zone. There are five Front Points (CV-12, CV-14, CV-17, LI-14, GB-24) that are matched with the location of pressing palpitation point and other Front Points are closely located to the pressing palpitation point. So far, it was clear that the Front Points do have important role as response points. Symptoms expressed to the Front Points were delivered conditions or symptoms occur in corresponding organ and the anatomical location of Front Points were also found near the corresponding organ. Diagnostic and therapeutic application of Front Points for Organ theory and in the Interpromotion-restraint of the five elements in oriental medicine can be made in future to increase its potential.
Distribution of Electrical Resistance in Medial Side of Forearm
Kim Gi-Wang ; Park Kyung-Mo ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 173~177
We have observed the electrical resistance of every point in a
matrix that is projected to the medial side of human forearm. The electrical resistance against the 1.25V directing current was rated in discrete scale and illustrated in contour maps. The characteristics of distribution of electrical resistance and it's relations to so called Meridians were also discussed.
The Effect of Juglandis Semen Extract Solution on Oxidant-Induced Alteration of Glutamate Uptake in Rabbit Brain Synaptosome
Kim Tae-Kook ; Youn Hyoun-Min ; Jang Kyung-Jeon ; Song Choon-Ho ; Ahn Chang-Beohm ;
Korean Journal of Acupuncture, volume 17, issue 1, 2000, Pages 179~190
This study was undertaken to determine whether Juglandis semen extract solution (JLS solution) exerts protective effect against oxidant-induced inhibition of glutamate uptake by synaptosomes. Synaptosome was prepared from rabbit brain cortex. Glutamate uptake increased by incubation time during 10 minutes, which was significantly inhibited by 1mM t-buthylhydroperoxide(t-BHP). JLS solution prevented t-BHP-induced inhibition of glutamate uptake in a dose-dependent manner. t-BHP reduced glutamate uptake in dose-dependent fashion, which was significantly prevented by 2% JLS solution. t-BHP(1mM) and
increased lipid peroxidation in synaptosomes by 5-fold, and it was significantly prevented by 2% JLS solution.
inhibited glutamate uptake and increased lipid peroxidation. These changes were prevented by 2% JLS solution. Synaptosomal Na-K-ATPase activity was inhibited by t-BHP(1mM) and
, which was prevented by 2% JLS solution. The results indicate that JLS solution prevents oxidant-induced inhibition of glutamate by synaptosomes, and this may result from inhibition of lipid peroxidation induced by oxidants.