Go to the main menu
Skip to content
Go to bottom
REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Korean Journal of Acupuncture
Journal Basic Information
Journal DOI :
Society for Meridian and Acupoint
Editor in Chief :
Volume & Issues
Volume 30, Issue 4 - Dec 2013
Volume 30, Issue 3 - Sep 2013
Volume 30, Issue 2 - Jun 2013
Volume 30, Issue 1 - Mar 2013
Selecting the target year
A Comparison Study of Acupuncture Points Selection between Classics of Traditional Medicine and Clinical Trials in Dental Disorders
Kim, Song-Yi ; Oh, Jihyeon ; Hong, Jaehwa ; Park, Sang Kyun ; Park, Hi-Joon ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 201~211
DOI : 10.14406/acu.2013.043
Objectives : The aim of this study is to summarize and compare acupuncture points used for dental disorder in the classics with those used in recent clinical trials. Methods : We searched the data for acupuncture points used and rationale of acupuncture in dentistry. Following two sources were searched: 1) seven Classics of traditional medicine and 2) clinical trials through Pubmed from January 2000 to March 2013 with no language restriction. Results : Dental pain was the most common disorder in the dentistry section of the Classics of traditional medicine. We found many similarities of acupuncture points used between literatures and clinical trials. From the meridian perspective, large intestine meridian(LI), stomach meridian(ST), triple energizer meridian(TE), and gallbladder meridian(GB) were frequently used in the Classics of traditional medicine and the clinical trials. From the acupuncture point perspective, acupuncture points were selected according to syndrome. The specific points such as five transport points, source points, and connecting points were also used. In the clinical trials, combination of acupuncture points usually consisted adjacent points and distant points. Among them, LI4 was used in all of the studies included in this review. Conclusions : For well-designed clinical trial, appropriate intervention is essential. To establish appropriate acupuncture treatment, we have to suggest reasoning for treatment based on literature and/or expert consensus. Our review only focused on pain relief in dentistry and had many limitations. Further studies based on the literatures such as the Classics of traditional medicine are required to ensure the rationale of acupuncture treatments in various dental disorders.
The Anti-Migratory Effect of Cirsium japonicum Pharmacopuncture in C6 Glioma Cell
Park, Juyeon ; Lee, Kangpa ; Chang, Haeryong ; Moon, Jinyoung ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 212~219
DOI : 10.14406/acu.2013.034
Objectives : Cirsium japonicum is a traditional Korean medicine that has been used in the treatment of inflammatory diseases such as appendicitis, hepatitis, pulmonary abscess and tumor. The aim of study was to elucidate anti-migratory activity of CJP(Cirsium japonicum pharmacopuncture) through regulation of inflammatory mediators in C6 glioma cell. Methods : Nitric oxide(NO) production was determined by using nitrite assay. The cell migration was analyzed by wound-healing assay and Boyden chamber assay. The expression levels of iNOS, and protein kinase C(PKC)-
were measured by western blotting assay. Results : CJP showed a significant decrease on NO production. Moreover, glioma cell migration was effectively suppressed by CJP. Furthermore, CJP inhibited the expressions of iNOS and PKC-
in C6 glioma cells. Conclusions : These results suggest that CJP inhibits glioma cell migration and iNOS expression through regulation of PKC-
. Therefore, it is expected that CJP could be an effective agents for blocking malignant progression of glioma.
The Mechanism for Analgesic Effects of Electroacupuncture on Surgical Ankle Sprain Model Classified as Grade 3 in Rats
Yang, Seung-Bum ; Choi, Suck-Jun ; Lee, Sung-Ho ; Kim, Min-Su ; Sohn, In-Chul ; Kim, Jae-Hyo ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 220~229
DOI : 10.14406/acu.2013.035
Objectives : Electroacupuncture(EA) has been used effectively in producing analgesia on ankle sprain pain of humans and animals. Currently to examine the underlying mechanisms of the EA-induced analgesia, the effects of EA on weight-bearing forces(WBR) were examined at ankle sprain classified as grade 3 in rats. Methods : The severe ankle sprain classified as grade 3 was induced surgically by ankle ligament injury in the Sprague-Dawley rats. WBR of the affected foot were examined to evaluate effects and mechanism of EA(2 Hz, 1 ms pulse width, 2 mA intensity, for 15 min) which was applied to either SI6, GB34, or GB39 acupoints. The rats were pretreated with naltrexone(10 mg/kg, i.p.) as an opioid receptor antagonist or phentolamine(5 mg/kg, i.p) as an
-adrenoceptor antagonist at 30 min before EA. Results : The daily repeat EA at either SI6, GB34, or GB39 showed significant analgesic effects on the severe ankle sprain. Particularly, daily EA at GB34 showed more potent analgesic effect than the others. In addition, the naltrexone pretreatment completely blocked the analgesic effect of EA at GB34, indicating the involvement of the endogenous opioid system in mediating the effect of EA at GB34. However, the phentolamine pretreament blocked analgesic effects of EA at either SI6 or GB39, indicating the involvement of
-adrenoceptors in mediating the effect of EA at either SI6 or GB39. Conclusions : These data suggest that EA-induced analgesia on ankle sprain pain is mediated through either endogenous opioids or
-adrenoceptors dependant on acupoint specific pattern.
A Structural Analysis of Acupuncture & Moxibustion Points in the NaeGyeong Chapter of DongUiBoGam Using Text Mining
Lee, Taehyung ; Jung, Won-Mo ; Lee, In-Seon ; Lee, Hyejung ; Kim, Namil ; Chae, Younbyoung ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 230~242
DOI : 10.14406/acu.2013.040
Objectives : DongUiBoGam is a representative medical literature in Korea. This research intends to structurally grasp how DongUiBoGam understands the human body and review the methods of acupuncture and moxibustion in the NaeGyeong chapter of it using text mining. Methods : The structure of DongUiBoGam was analyzed with specific parts of the book that described contents, major premises of understanding the human body, and processes of treatment. We analyzed characteristics of each acupoints in a relationship with causes of diseases & symptoms in the NaeGyeong chapter using a Term Frequency - Inverse Document Frequency(TFIDF). Results : Three different categories of pattern identification(PI) were formed after structural analysis of DongUiBoGam. Every causes of diseases & symptoms were transformed according to the three categories of PI. After analyzing the relationship between acupoints and causes of diseases & symptoms, 114 acupoints were visualized with TFIDF values of three PI categories. Conclusions : The selection of acupoints in NaeGyeong chapter of DongUiBoGam were linked to causes of diseases & symptoms based on the three PI categories. Through visualization of bipartite relationships between acupoints and causes of diseases & symptoms, we could easily understand characteristics of each acupoint.
Anti-Inflammatory Effect of Bower Actinidia in LPS-Stimulated RAW264.7 Cells
Kim, Young-Jun ; Song, Choon-Ho ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 243~251
DOI : 10.14406/acu.2013.039
Objectives : Bower Actinidia has been widely used for treatment of inflammatory diseases, such as jaundice, cystolithiasis. However, the mechanism of its anti-inflammatory activity has not been clarified. In this study, we investigated the inhibitory effect of Bower Actinidia pharmacopuncture extract(BA) on LPS-induced inflammation. Methods : The effect of BA was analyzed by ELISA, RT-PCR and Western blotting in LPS-stimulated RAW264.7 cells. Results : We found that BA suppressed not only the mRNA expression of pre-inflammatory cytokines, cyclooxygenase-2(COX-2) and inducible nitric oxide synthase(iNOS), but also the phosphorylation of ERK, JNK and p38. Conclusions : These results suggest that BA exerts an anti-inflammatory effect through the regulation of the mitogen-activated protein kinase(MAPK) pathway, thereby decreasing production of pre-inflammatory cytokines.
A New Method For Measuring Acupoint Pigmentation After Cupping Using Cross Polarization
Kim, Soo-Byeong ; Jung, Byungjo ; Shin, Tae-Min ; Lee, Yong-Heum ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 252~263
DOI : 10.14406/acu.2013.048
Objectives : Skin color deformation by cupping has been widely used as a diagnostic parameter in Traditional Korean Medicine(TKM). Skin color deformation such as ecchymoses and purpura is induced by local vacuum in a suction cup. Since existing studies have relied on a visual diagnostic method, there is a need to use the quantitative measurement method. Methods : We conducted an analysis of cross-polarization photographic images to assess the changes in skin color deformation. The skin color variation was analyzed using
space and the skin erythema index(E.I.). The meridian theory in TKM indicates that the condition of primary internal organs is closely related to the skin color deformation at special acupoints. Before conducting these studies, it is necessary to evaluate whether or not skin color deformation is influenced by muscle condition. Hence, we applied cupping at BL13, BL15, BL18, BL20 and BL23 at Bladder Meridian(BL) and measured blood lactate at every acupoint. Results : We confirmed the high system measurement accuracy, and observed the diverse skin color deformations. Moreover, we confirmed that the
and E.I. had not changed after 40 minutes(p>0.05). The distribution of blood lactate levels at each part was observed differently. Blood lactate level and skin color deformation at each part was independent of each other. Conclusions : The negative pressure produced by the suction cup induces a reduction in the volumetric fraction of melanosomes and subsequent reduction in epidermal thickness. The relationship between variations of tissue and skin properties and skin color deformation degree must be investigated prior to considering the relationship between internal organ dysfunction and skin color deformation.
Effects of Acupuncture at LI5, SI5, TE6 on Changes of NO and NOSs in Rats
Kim, Youngsun ; Choi, Donghee ; Jang, Hosun ; Na, Changsu ; Choi, Taejin ; Hwang, Moonhyeon ; Cho, Joohyun ; Lee, Kyoungin ; Kim, Sunmin ; Pyo, Byoungsik ; Youn, Daehwan ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 264~271
DOI : 10.14406/acu.2013.046
Objectives : To observe the changes in the expression of neurotransmitters NO and enzymes that create NO, such as nNOS, iNOS and eNOS, upon the needle insertion on river point, one of the five transport points of three yang meridians on the forefoot. Methods : Based on rats, needle was inserted on both sides of LI5, SI5 and TE6, which are river points of three yang meridians on the forefoot, and were retained for five minutes. After the retention, blood was drawn via cardiac puncture and tissues from each point around meridian vessels were extracted to be examined on the changes of the expression of NO, as well as of nNOS, iNOS and eNOS. Results : In terms of the effect on NO creation in tissues, none of the experimental groups showed any significant change compared to the Normal group. In terms of the effect on expression of nNOS within tissues, LI5 and SI5 showed significant increase based on the results of immunohistochemistry. In iNOS within tissues, LI5 and SI5 showed significant increase based on the results of immunohistochemistry. In eNOS within tissues, SI5 showed significant increase based on the results of immunohistochemistry. Conclusions : The effect on the function of NO, nNOS, iNOS and eNOS of needle insertion on the river points of three yang meridians on the forefoot could be observed, and based on this study, it is considered that the effect of needle stimulation on the changes of nervous system could be found out through additional research.
Effects of Acupuncture and Moxibustion at Lower Sea Points on the Intestinal Motility with Loperamide-Induced Constipation in Rats
Yu, Yun-Cho ; Kwon, O-Sang ; Yang, Seung-Bum ; Kim, Min-Su ; Kim, Jaehyo ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 272~280
DOI : 10.14406/acu.2013.038
Objectives : The aim of this study was to observe effects of manual acupuncture(MA), electro-acupuncture(EA) and moxibustion (MO) on the rat with loperamide-induced constipation. Methods : This study measured small intestinal motility and number of fecal pellets in rats with loperamide induced constipation. MA and EA(intensity, 5 times muscle twitch threshold) was applied for 30 minutes and MO was treated on 5 times moxa cautery to the groups divided with age and sex. Results : The small intestinal motility was decreased by ST36 EA and ST37 EA in 5 weeks male group and ST37 EA in 7 weeks male and female groups, and ST36 MO in 7 weeks female group, but it was increased by ST39 EA in 7 weeks male group and ST37 MO and ST39 MO in 7 weeks male group. The number of fecal pellets was decreased by MA, EA, MO of ST36 in all group except 5, 7 weeks male groups only, and MA, EA of ST37 in 5, 7 weeks male group and ST37 MO in 7 weeks female group, and ST39 EA in 5 weeks male group and 7 weeks female group and ST39 MO in 7 weeks female group, but increased by ST37 EA in 5 weeks female group and ST39 EA in 7 weeks male group. Conclusions : Although these differences do not have a established tendency, it suggests that acupuncture and moxibustion are experimentally dependent upon the sex and age on intestinal motility in rats.
The Effect of Stephaniae tetrandrae Radix Herbal-acupuncture at KI10 on LPS Induced Nephritis in Rats
Kim, Ki-Choon ; Yim, Yun-Kyoung ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 281~288
DOI : 10.14406/acu.2013.049
Objectives : This study aimed to evaluate the effects of Stephaniae tetrandrae Radix Herbal-acupuncture(SR-HA) at KI10(Umgok) on nephritis induced by lipopolysaccharide(LPS) in rats. Methods : Male SD rats (n=32) were allocated to four groups; normal, LPS, saline, and SR-HA. The rats in the LPS, saline, and SR-HA groups were injected intra-peritoneally with LPS (2 mg/kg) to induce nephritis. The rats in the saline and SR-HA groups were treated with saline injection and SR-HA respectively at KI10 three times a week. To evaluate the effects of SR-HA at KI10 on nephritis in rats, the authors evaluated the numbers of WBC and neutrophils in blood, and the levels of creatinine, TNF-
, CINC-1 in serum, creatinine, total protein in urine and renal MPO. Results : SR-HA at KI10 significantly inhibited the increase of WBC and neutrophils in blood, TNF-
, CINC-1 in serum, creatine, total protein in urine and MPO in kidney of LPS-stimulated rats. Conclusions : SR-HA at KI10 may have therapeutic effects on nephritis in LPS-stimulated rats.
Efficacy of Saam Acupuncture for Diabetic Peripheral Neuropathy - A Pilot, Randomized Controlled Study
Jeon, Eonju ; Kwon, Hyojung ; Shin, Imhee ; Jung, Euidal ; Kang, Seokbong ; Shon, Hosang ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 289~297
DOI : 10.14406/acu.2013.042
Objectives : Diabetic peripheral neuropathy(DPN), generally considered to be the most symptomatically distressing complication of diabetes, affects more than 50% of people with diabetes. However, no consistently effective treatment for DPN is available and patients are forced to struggle with medications that provide only partial relief. In this pilot study, we evaluated the clinical effects of Saam acupuncture for the treatment of painful DPN. Methods : A total of 10 patients with painful DPN were included in the study; 6 subjects with Saam acupuncture treatment and 4 subjects without it. Subjects were defined as having painful DPN if they had at least 2 points using total symptom score(TSS). Treatments were delivered three times a week for 4 weeks. Vitamin
was orally administrated in the all subjects. At initial(0 week) and follow-up after 4 weeks and 8 weeks, all subjects underwent TSS, Michigan Neuropathy Screening Instrument(MNSI), and nerve conduction test. Results : After initial(0 week) and follow-up(8 weeks), TSS and MNSI were not significantly different between the two groups(p=0.400 and p=0.830, respectively). However, in both two groups, according to time, there was a significant difference in TSS as well as MNSI(p=0.001 and p=0.004, respectively). Conclusions : Saam acupuncture may be considered as the effective treatment for the patients of DPN although the changes of the symptoms were of limited significance in this study. Further investigations are required to elucidate the role of Saam acupuncture for the pain control of DPN.
Mutual Inhibitory Effects of Electroacupuncture Applied to Combination of ST36 and PC7 in the Rat Model of Arthritis
Kim, Yeojung ; Jung, Yunjung ; Lee, Chang-Hyung ; Koo, Sungtae ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 298~304
DOI : 10.14406/acu.2013.045
Objectives : We examined mutual inhibitory effects of combined acupoints in arthritic pain induce by carrageenan(CA). Electroacupuncture(EA) is considered a potentially useful treatment for arthritis. Although the analgesic effect of acupuncture is well documented, little is understood about its biological basis. There are many previous studies of positive effect of combined acupoint, this study was conducted to see the mutual inhibitory effects produced by combined acupoint(ST36 and PC7) on arthritic rats. Methods : For the induction of inflammatory pain rat model, CA was injected into the knee joint cavity. There are four groups; EA was applied to bilateral PC7 acupoints(PC7 group), ST36 acupoints(ST36 group), and both PC7 and ST36 acupoints(ST36+PC7 group) except for the control group. The pain level were assessed to determine the change in weight bearing force. We also examined the COX-2 expression in dorsal horn using immunohistochemistry and western blot analysis. Results : The ST36+PC7 group data showed the significant reduction of weight bearing force and the induction of COX-2 protein expression compared with the ST36 group. Conclusions : Simultaneous EA applied to the ST36 and PC7 acupoints reduced the analgesic effect of the ST36 group on knee inflammatory pain.
The Effect of Electroacupuncture at Sobu(HT8) on the EEG and HRV
Yoon, Dae Shik ; Hong, Seung-Won ; Lee, Yong-Sub ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 305~318
DOI : 10.14406/acu.2013.050
Objectives : The aim of this study was to examine the effect of electroacupuncture(EA) at an acupoint, HT8(Sobu), on normal humans by using power spectral analysis. We examined the effect on the Heart Rate Variability(HRV), and the balance of the autonomic nervous system. Methods : Thirty-two healthy volunteers participated in this study. EEG(Electroencephalogram) power spectrum exhibits site-specific and state-related differences in specific frequency bands. A thirty-two channel EEG study was carried out on thirty-two subjects(14 males; mean age=23.5 years old, 18 females; mean age=21.5 years old). HRV and EEG were simultaneously recorded before and after acupuncture. Results : In the
(alpha) band, during the HT8-acupoint treatment, the power values in the
(alpha) band significantly decreased(p<0.05) at 28 channels. In the
(beta) band significantly decreased(p<0.05) at 26 channels. In
(delta) band significantly decreased(p<0.05) at 18 channels. In
(theta) band significantly decreased(p<0.05) at 20 channels.
values were increased at 6 channels and decreased at 10 channels.
values were increased at 10 channels and decreased at 19 channels. Mean-RR(RR-interval), Complexity, RMSSD(Root mean square of successive differences), SDSD(Standard deviations differences between adjacent normal R-R intervals), norm HF showed a significantly increased and mean-HRV, norm LF, LHR(LF/HF Ratio) showed a significantly decreased after HT8-acupoint treatment(p<0.05). Conclusions : These results suggest that EA at the HT8 mostly causes significant changes on alpha(28 channels), beta(26 channels), delta(18 channels), theta(20 channels) bands and mean-HRV, mean-RR, complexity, RMSSD, SDSD, norm LF, norm HF and LHR. If practicing EA at the HT8, it will regulate the function of the cerebral cortex, decrease activity of the sympathetic and increase parasympathetic nervous activity.
The Retrospective Comparative Study of General Acupuncture Therapy and Hominis placenta Pharmacopuncture Therapy on Severe Dyspepsia
Lee, Ah-Ram ; Kim, Won-Il ;
Korean Journal of Acupuncture, volume 30, issue 4, 2013, Pages 319~328
DOI : 10.14406/acu.2013.041
Objectives : The purpose of this research was to compare the effect of general acupuncture therapy to Hominis placenta Pharmacopuncture therapy on pain and discomfort of severe dyspepsia in upper abdomen. Methods : We investigated 60 cases of patients with severe dyspepsia, who had been treated at Dept. of Internal Medicine, College of Oriental Medicine Dongeui University from May 2011 to September 2012. We divided patients into two groups : Group I was treated by general acupuncture(ACU, n=30) and Group II was treated by Hominis placenta Pharmacopuncture therapy(PHA, n=30). The symptoms and quality of life were measured with the Nepean dyspepsia index-Korean version(NDI-K) at baseline and 2 weeks. The responsiveness of the NDI-K was evaluated by correlation with symptom scores. Results : In ACU group, the 13 symptom scores were significantly decreased after treatment(p<0.05). In PHA group, the 9 symptom scores were significantly decreased after treatment(p<0.05). In ACU group, the 3 Quality of life(QOL) scores were significantly increased after treatment(p<0.01). In PHA group, the 3 QOL scores were significantly increased after treatment(p<0.05). Conclusions : General acupuncture therapy and Hominis placenta Pharmacopuncture therapy improves the symptoms and the quality of life in patients with severe dyspepsia. But there were no significant differences statistically between the two groups.