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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
The Journal of Pediatrics of Korean Medicine
Journal Basic Information
Journal DOI :
The Association of Korean Oriental Pediatrics
Editor in Chief :
Volume & Issues
Volume 23, Issue 3 - Dec 2009
Volume 23, Issue 2 - Aug 2009
Volume 23, Issue 1 - Apr 2009
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A Case Report of a Child who has Urolithiasis with Urinary Tract Infections
Jung, Ji-Ho ; Kim, Mi-Ki ; Oh, Ji-Eun ; Ahn, Jae-Sun ; Eun, Seon-Hye ; Park, Ga-Young ; Lee, Hai-Ja ; Park, Eun-Jung ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 1~8
Objectives A purpose of this study is to report a case study of a child with urolithiasis and urinary tract infections. Methods A four-year-old female had been taken Korean traditional medicine for two weeks, and clinical symptoms had been observed. Results Treating with Korean traditional medicine, symptoms of urolithiasis with urinary tract infections has been improved. Conclusions This study supports that Korean traditional medicine can be an effective means of treating internal medicine for urolithiasis with urinary tract infections, and further case studies are needed for more accurate results.
Effects of Concurrent Administration of JaUmJeSeupTangKaKam(JUJSTK) and Atopy Cream, Jawoongo(AJ) on Atopic Dermatitis-like Skin Lesions in NC/Nga Mouse
Lee, Nam-Yerl ; Kim, Yun-Hee ; Han, Jae-Kyung ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 9~36
Objectives The purpose of this study is to examine the effect of a concurrent administration of JUJSTK and AJ on atopic dermatitis in an in-vivo experiment. Thus, this study is expressed by using NC/Nga atopic dermatitis mice which have histological and clinical similarities to that of humans have been used. Methods Clinical skin score, hematology, serum total IgE and IgG1 of the mouse was evaluated, and cytokine levels, total number of the cells, immunohistochemical staining, histological features of axillary lymph node(ALN), peripheral blood mononuclear cells(PBMCs), and a dorsal skin tissue of the mouse were analyzed. Results Oral administration of JUJSTK and concurrent administration of JUJSTK and AJ lowered the clinical skin score, total cell number of WBC, eosinophils in blood, and serum total of IgE & IgG1, IFN-
, IL-5, IL-13, IL-17. In addition, total cell number of ALN and dorsal skin tissue, absolute cell number of
in ALN, PBMCs, absolute cell number of
in dorsal skin tissue, Eotaxin2 mRNA, CCR3 mRNA in dorsal skin tissue and gene expression of IL-5 mRNA, IL-13 mRNA in ALN were significantly decreased. Furthermore, thickness of epidermis infiltrated inflammatory immune cell & mast cell in dermis, histological infiltration of mast cell, the size of inflammatory lymphocytes cells & plasma cells in ALN and histological infiltration of
in ALN and dorsal skin tissue were significantly decreased as well. Conclusions Concurrent administration of JUJSTK and AJ on atopic dermatitis in an in-vivoexperiment by using an NC/Nga atopic dermatitis mouse was very effective as an atopic dermatitis treatment.
Comparison of Eating Habits and Living Habits in Fourth Grade Elementary School Children with or without Allergic Diseases
Seo, Hui-Yeon ; Han, Jae-Kyung ; Kim, Yun-Hee ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 37~53
Objectives Because allergic disease is currently prevalent and has tendency to become chronic, the purpose of this study is to examine the effects of allergic diseases on eating and living habits of children when they grow. Methods Questionnaire performed by 203 fourth grade elementary school children in Cheonan was analyzed. Results Disease group had low frequency of eating ramen, watching TV or web-surfing than that of normal group, but had higher frequency of eating meat, eating breakfast. Conclusions The allergic disease group had more desirable habits. It was assumed that parent's greater interest and devotion toward their children to cure their allergic disease was the reason for the children's desire habits.
Oriental Medical Research about School Life Maladjustment by Study of the Weak Children Symptoms
Son, Mi-Ju ; Han, Jae-Kyung ; Kim, Yun-Hee ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 55~69
Objectives This study is designed to evaluate the relationship between school life maladjustment and oriental medicine by diagnostic procedure based on the symptoms of weak children. Methods The questionnaire administrated to 130 fifth grade elementary school students in Daejeon was analyzed. Results 1. Comparing and analyzing different sexes in terms of school adjustment grades, girls were more adaptable than boys. 2. Weak score didn't show significant difference in sex and in the school adjustment 3. Based on the relationship between a group normal children and a group of children with weak lung, normal children group was more adaptable than group of children with weak lung. Conclusions School life maladjustment should be investigated as a new field of oriental medical treatment and further study needs to be done.
The Correlation Study between Interference Test with the Weak Children(虛弱兒) Symptoms
Gok, Su-Yeong ; Lyu, Sun-Ae ; Lee, Seung-Yeon ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 71~88
Objectives The purpose of this study is to find out the correlation between Stroop interference and the symptoms of weak children. Methods Questionnaire and performed Stroop interference test were done by 145 patients in OO Oriental Medical Hospital from May to October 2009. 120 patients who were considered as the weak children were divided into two groups: Stroop Interference T score above average group and below average group, and were surveyed again. Results 1. The study showed that age, the highest marked subject and behavior habits correlate to interference score and subjects characteristics. 2. Weak children groups had the highest tendency of having weak heart followed by weak lung spleen, liver, and kidney. Normally, a patient belonged to more than one of the weak children groups. 3. The study showed that a group of children who has weak heart and lung were related to interference score. The group which earned below average interference score had the highest frequency of being children with weak heart group. The group scored above average, however, had the highest chance of being children with weak lung group. 4. The study showed that interference score was related to four out of fifty questions about the weak children symptoms. Plus, related questions were all about the heart weak children symptoms. Conclusions In conclusion, there were significant correlation between interference score and the group consists of children who were weak: more specifically with children with weak heart.
A Case Report of Primary Developmental Disorder Induced by Traumatic Brain Injury
Sung, Hyun-Kung ; Min, Sang-Yeon ; Kim, Jang-Hyun ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 89~108
Objectives The purpose of this study is to report the clinical effects of oriental medical treatment on developmental disorder induced by traumatic brain injuries. Methods The patients were treated with herb medicine, acupunctures, moxibustions, and negative pressures, and then evaluated by manual muscle tests, gross motor function measurements, sequenced language scales for infants. Results The patient's manual muscle power, motility, cognition, speech were significantly improved after six weeks of oriental medical treatment. Conclusions This study showed that oriental medical treatments were effective on developmental disorder induced by traumatic brain injuries. However, further clinical studies were needed.
An Observation of the Chief Complaints of Padiatric Inpatients in the Oriental Hospital
Cheon, Jin-Hong ; Yu, Hyun-Young ; Kim, Ki-Bong ; Min, Sang-Yeon ; Kim, Jang-Hyun ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 109~119
Objectives The purpose of this study is to collect the statistics of pediatric problems and to develop more effective oriental medical treatments for pediatric diseases, their clinical applicability, and chief complaints on pediatric inpatients in oriental hospitals. Methods The study was composed of seventy inpatients that were age from 0 to 20, had received hospital treatment at the pediatrics in Dongguk Bun-Dang Oriental Medicine Hospital for seven years from 1 January 2002 to 31 December 2008. The chief complaints were mainly categorized by oral examination on their patients. Results 1. In this study, male children were thirty one and female children were 39. Thus, sex ration of male to female was 0.79:1. 2. In age distribution, one month to one year were three (4.3%), 1 to six years were forty two (60%), six to ten years were fifteen (21.4%), and ten to twenty years were ten (14.3%). 3. In November, the number of inpatients was the highest (15.7%) in a year. However, there were no significant seasonal differences. 4. In the systemic division, the respiratory diseases : 44(62.9%), the digestive diseases : 11(15.7%), the infectious diseases : 5(7.1%), the musculoskeletal diseases : 3(4.3%), the diseases of nervous system : 3(4.3%), the gynecologic diseases : 1(1.4%), the liver and biliary disorders : 1(1.4%), and etc. : 3(4.3%). 5. The chief complaint of the inpatients is pneumonia, a common cold, respiratory complex symptoms, rhinitis, sinusitis, bronchitis, tonsillitis, diarrhea and etc. Conclusions The two main causes of inpatients were respiratory diseases and digestive disease. More data of inpatients are required for further study. Thus, the new diseases and treatment methods should be studied as a field of oriental medical treatment.
A Case Report of Functional Dyspepsia with Abdominal Distention
Kim, Cho-Young ; Chang, Gyu-Tae ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 121~131
Objectives This study is to report a case that has an important meaning as a result of treating functional dyspepsia with oriental treatment. We investigated functional dyspepsia in 6 years child who had to continue abdominal distention for a month after gastroenteritis. The child has recovered from all dyspepsia symptoms after treating with oriental medicine. Methods The patient had dyspepsia symptoms all day, especially repeated abdominal distention. He sometimes had nausea, vomiting, diarrhea, abdominal pain. For those symptoms, we treated him with herbal medicine and acupuncture. The aim of treatment was to improve functional dyspepsia without western treatment. We measured patient's abdomen circumference for change of abdominal distention. Results The symptoms of functional dyspepsia were vanished and the patient maintains his condition with oriental medicine treatment without western treatment. After herb medicine treatment and acupuncture treatment the patient's dyspepsia symptoms (nausea, vomiting, diarrhea, abdominal pain, and abdominal distention) were vanished and maintained his condition for two months after complete the treatment. Conclusions This study showed that oriental medicine can elevate the functional dyspepsia children's quality of life with continuous health care and treatment. For more accurate studies, further studies would be needed with more cases.
A Clinical Report of Scalp Acupuncture Effects on Autistic Children
Hong, Sang-June ; Choi, Ka-Hye ; Song, In-Sun ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 133~142
Objectives The study was designed to report the clinical effects of scalp acupuncture on autistic children. Methods These patients were treated by scalp acupuncture. We observed the improvement of his disease through K-CARS and E-CLAC tests. Results By using scalp acupuncture, we could make a considerable improvement of autistic score(K-CARS). Conclusions The above results suggest that scalp acupuncture can be an effective treatment for autistic children.
A Study on the State of Health Functional Foods & Herbal Medicine Consumed by Elementary School Students
Kim, Mi-Ki ; Jung, Ji-Ho ; Ahn, Jae-Sun ; Yim, Jung-Hoon ; An, Min-Seop ; Park, Jin-Su ; Lee, Hai-Ja ; Park, Eun-Jung ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 143~153
Objectives The purpose of this study is to get the basic information from patients how much they understood about their medication and also to know whether patients are making reasonable drug choice between Health Functional Foods and Herbal medicine. Methods 500 questionnaires were handed out to the parents of students in two elementary schools located in OO, Junlabukdo province. 421 questionnaires were completed to be evaluated. Results Among 421 subjects, 53.0% were female, and 47.0% were male. The percentages of the subjects consuming Health Functional Foods and herbal medicine were67.7% and 67.8%, respectively. Among those people who consumed Health Functional Food, 44.1% were using nutritional supplements, red ginseng or ginseng products (26.9%), chlorella products (11.5%), and plum extract products (7.7%). As for the reason to consume Health Functional Foods were varied, but 'in order to be healthy, although currently displaying no illness.'(43.0%) were the most responses among the given choices. On the other hand, the reason for consuming herbal medicine was 'In order to grow taller'(26.1%), 'In order to cure weak physical state frequently displaying common illnesses',(25.9%), and 'In order to cure diseases.'(23.3%). For the questions about effectiveness after consumption,the 69.9% subjects said that it seemed to be effected, and that % was slightly higher than that of subjects with consuming Health Functional Foods(64.4%). For question concerning preferences between Health Functional Foods and herbal medicine, 57.5% chose herbal medicine, and this percentage was higher than that of Health Functional Foods(42.5%).As for the reasons of additional consumption of the Health Functional Foods, subject answered as 'Easy to consume.'(41,6%), which was the most common among the subjects consuming Health Functional Foods. On other hand, the subjects of herbal medicine answered as that herbal medicine is 'more effective'(45.7%), and 'more trustworthy in preventing side-effects.'(40.3%). After consumption of the herbal medication, only 3.9% of the subjects consuming either Health Functional Foods or herbal medicine had side-effects. The most common side-effects were 'dermal reaction' which is normally caused by Health Functional Foods and 'indigestion' problems caused by herbal consumption. Conclusions According to the 421 subjects those involved in study, the percentages of consuming Health Functional Foods(67.7%) and herbal medicine(67.8%) were similar. The most commonly consumed products were a type of Health Functional Foods which were the nutrition-supplying products. Ginseng or red ginseng products were the next commonly used products. Health Functional Foods were commonly consumed for preventing illness and maintaining health rather than any other purpose. In contrary, herbal medicines were more commonly consumed for purposes such as for growth or treating certain type of disease. As a result of consumption, more than half of both subject replied as 'satisfied'. As for the side effects, dermal reaction was the most common problem for those with consuming Health Functional Foods, while indigestion was the most common side effect from the subjects with consuming herbal medicine.
A Case Report of a Sequela of Intracranial Hemorrhage in Childhood
Choi, Ka-Hye ; Hong, Sang-June ; Song, In-Sun ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 155~163
Objectives The purpose of the case study is to report the effects of stroke in childhood especially for Intracranial Hemorrhage sequela treated by oriental medical treatment. Methods The patient was treated by herbal medicine, acupuncture, moxa, and physical treatments. Results By using of oriental medical treatment, we could see significant improvement for Stroke symptoms. Conclusions This case study shows that oriental medical treatment can be an effective treatment for Stroke in Childhood. However, the further study with longer, and large clinical trials are needed for accuracy.
Inhibitory Effect of Taraxaci Herba Extract (THE) on Pro-inflammatory Mediatory
Noh, Kyung-Ho ; Baek, Jung-Han ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 165~176
Objectives The purpose of this study is to find out the effect of Taraxaci Herba Extract (THE), LPS, on pro-inflammatory mediatory. Methods After the treatment of Taraxaci Herba MeOH extract dissolved in EMEM for 1 hour prior to the addition of LPS (
), cell viability was measured by MTT assay, Nitric Oxide production was monitored by measuring the nitrite content in culture medium. And levels of cytokine and PGE2 were analyzed by sandwich immunoassays. Results THE inhibited the production of nitrite and nitrate (0.03 and 0.1 mg/ml), TNF-
, (0.03 and 0.1 mg/ml), IL-
(0.03 and 0.1 mg/ml), IL-6 (0.01, 0.03 and 0.1 mg/ml) and PGE2(0.03 and 0.1 mg/ml) activated with LPS. In Raw 264.7 cells activated with lipopolysaccharide. Conclusions According to the results above, Taraxaci Herba can produce anti-inflammatory effect, which may play a role in adjunctive therapy in Gram-negative bacterial infections.
The Effect of InsamGobonHwan (IGH) on Growth of Rats
Park, Sun-Young ; Baek, Jung-Han ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 177~191
Objectives To evaluate the effect of InsamGobonHwan (IGH) on growth of rats. Methods We divided male Sprague-Dawley rats into 4 groups(IGHE1, IGHE2, IGHE3 and sham group). IGHE1, IGHE2, IGHE3 groups were administered with IGHE water extracts once a day at the dose of 1,000, 500 and 250mg/kg/
for 1 week, 2 weeks, and 3 weeks. Sham group was administered with normal saline with using the same method. We measured body weight, amount of body weight increasing, length of femur, serum Growth Hormone(GH), serum Insulin-like Growth Factor-I(IGF-I), serum Thyroid-stimulating Hormone(TSH) and serum testosterone at 1 week, 2 weeks, and 3 weeks of experiment. Results The body weight and the changes of body weight increased significantly in IGHE1 group compared to sham group after 2 and 3 weeks, and in IGHE2 group after 2 weeks. The lengths of the femur increased significantly in IGHE1 group as compared with sham group after 1, 2 and 3 weeks, and in IGHE3 group after 1 week. The level of IGF-I in the serum increased significantly in S1 group as compared tosham group after 1 and 3 weeks, and in IGHE13 group after 3 weeks. The level of TSH in the serum increased significantly in IGHE1group as compared to sham group after 2 and 3 weeks. The level of GH and testosterone in the serum does not change significantly. Conclusions SGT have an effect of promoting growth of rats and might be effect to treat various kinds of growth delay in children.
The Effects of Low Level Laser Therapy on Decrease of Atopic Dermatitis Symptoms
Yoon, Hye-Joon ; Yoon, Jong-Sung ; Kim, Deog-Gon ; Lee, Jin-Yong ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 193~206
Objectives The purpose of this study is to evaluate the effects of Low Level Laser Therapy on Atopic dermatitis symptoms. Methods 19 patients (7 men, 12 women) were involved in this study. The intensity of SCORAD index (Erythema/darkening, Edema/papulation, Oozing/crust, Excoriation, Lichenification/prurigo, Dryness) and the symptom of SCORAD index (Pruritus) in two regions were measured. One region was treated by LLLT, the other region was not treated. Then a comparative study of index score of two regions was analyzed. Results After treatment, there were statistically significant differences in Edema/papulation, Excoriation (p<0.001), Oozing/crust (p<0.01), and Pruritus(p<0.05) index. Conclusions Based on the results, we concluded that LLLT is an effective in the treatment of atopic dermatitis. Also, further controlled studies with clinical cases of appropriate treatment time, wavelength, and intervals are needed.
Three Cases Report of Children Psoriasis treated by Bangpungtongsungsan
Lee, Ki-Hoon ; Chang, Gyu-Tae ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 207~216
Objectives The purpose of these 3 cases study is to report the effects of psoriasis children treated by oriental medicine. Methods The subjects are 3 children diagnosed as having psoriasis. These patients were treated by oriental herbal medicine(Bangpungtongsungsan). We observed the improvement of skin condition by Psoriasis Area and Severity Index(PASI) score. Results After treatment, the symptoms of psoriasis were relieved. PASI score of three children in psoriasis was respectively changed from 7 to 0, 2.4 to 0, 3.6 to 0. Conclusions This study shows that Bangpungtongsungsan can be an effective treatment for psoriasis. Further study in needed with more cases of treatment.
The Effects of Puerariae Radix on Allergic Inflammation
Kim, Hong-Bae ; Kang, Kyung-Hwa ; Hwang, Won-Deuk ; Lyu, Sun-Ae ; Lee, Seung-Yeon ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 217~231
Objectives To evaluate that Okwada affected which factors for treatment of lung fibrosis. Methods Bleomycin induced lung fibrosis model made in mice. After Okwada lyophilized, power sample obtained and melt in distilled water. Okwada solution administered mice through oral route on 21 days after bleomycin instillation and this procedure performed once a day for 7 days. We divided by three groups; normal (control), bleomycin induced lung fibrosis without treatment (experimental), bleomycin induced lung fibrosis with treatment (treatment). On six weeks after bleomycin instillation, mice sacrificed and removed lung. We performed Western blot analysis for TGF-beta, phosphodiesterase 5A, interleukin (4,5,13) and compared therapeutic effects of Okwada. Results On western blot analysis, all normal and experimental mice detected TGF-beta, phosphodiesterase 5A, interleukin 4,5,13. The amount of band of TGF-beta, phosphodiesterase 5A, interleukin 5 in experimental and treatment group was similar. However, interleukin 4,13 of treatment group decreased compared with experimental group. Conclusions Okwada would be effected the lung fibrosis through suppression of interleukin 4,13.
The Effects of Okwada on the Lung Fibrosis Mouse Model
Lee, Hai-Ja ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 233~240
Objectives To evaluate that Okwada affected which factors for treatment of lung fibrosis. Methods Bleomycin induced lung fibrosis model made in mice. After Okwada lyophilized, power sample obtained and melt in distilled water. Okwada solution administered mice through oral route on 21 days after bleomycin instillation and this procedure performed once a day for 7 days. We divided by three groups; normal (control), bleomycin induced lung fibrosis without treatment (experimental), bleomycin induced lung fibrosis with treatment (treatment). On six weeks after bleomycin instillation, mice sacrificed and removed lung. Weperformed Western blot analysis for TGF-beta, phosphodiesterase 5A, interleukin (4,5,13) and compared therapeutic effects of Okwada. Results On western blot analysis, all normal and experimental mice detected TGF-beta, phosphodiesterase 5A, interleukin 4,5,13. The amount of band of TGF-beta, phosphodiesterase 5A, interleukin 5 in experimental and treatment group was similar. However, interleukin 4,13 of treatment group decreased compared with experimental group. Conclusions Okwada would be effected the lung fibrosis through suppression of interleukin 4,13.
The Effects of Jujadokseo-hwan on the Activation of Brain and Neuroprotactive Effects
Lee, Yu-Gyung ; Chae, Jung-Won ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 241~262
Objectives This study is designed to investigate the effects of Jujadokseo-hwan on the brain ability and inducing oxidative stresses. Methods We measured the changes of regional cerebral blood flow and mean arterial blood pressure. Then we analyzed histological examination, immunohistochemistric response and anti-oxidant activity of Jujadokseo-hwan. Results 1. Treatment of Jujadokseo-hwan significantly increased regional cerebral blood flow but decreased mean arterial blood pressure. 2. Treatment of Jujadokseo-hwan-induced increase of regional cerebral blood flow was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase. 3. In histological examination through TTC stain, group I was no change, but group II showed that discolored in the most cortical part. Group III showed that decreased discolor in the cortical part. 4. In immunohistochemistric response of BDNF, group II showed that lower response effect. Group III showed that increase response effect. 5. Treatment of Jujadokseo-hwan increased proliferation rates of Glial cell effectively 6. Treatment of Jujadokseo-hwan accelerated proliferation rates of C6 cells in vitro. In addition, protective effects on cell death induced by paraquat, rotenone and hydrogen peroxide. In addition, activity of SOD were increased by treatment with Jujadokseo-hwan. Conclusions In conclusion, Jujadokseo-hwan can improve of the brain ability, learning ability, memory ability and induce ischemic brain injuries.
Effect of Yanghyeoljeseuptang (YHJST) Composition on Atopic Dermatitis NC/Nga Mice Induced by DNCB(dinitrochlorobenzene)
Park, Doo-Byoung ; Han, Jae-Kyung ; Kim, Yun-Hee ;
The Journal of Pediatrics of Korean Medicine, volume 23, issue 3, 2009, Pages 263~291
Objectives The purpose of this study is to investigate the effect of YHJST on atopic dermatitis in an experiment using an NC/Nga mice induced by DNCB, which has histological and clinical similarities to the condition in humans. Methods To investigate the effect of YHJST on atopic dermatitis(AD), we evaluated atopic dermatitis-like skin lesions by clinical skin index and analyzed immunological parameters in peripheral blood mononuclear cells(PBMCs) and performed skin histology in ears and dorsal skin of NC/Nga ato-mouse. Results YHJST medicines decreased Serum level of IgE, IL-6, TNF-
. Also total number of
in PBMCs, absolute cell number of
in Dorsal skin tissue, Serum IgG1, IgM, IgG2a and IgG2b decreased significantly. Furthermore YHJST is extremely effective to histological symptoms; dermal and epidermal thickening, hyperkeratosis and inflammatory cell infiltration and suppressed histologic infiltration of
in ear and dorsal skin lesions significantly. YHJST decreased gene-expression of IL-6, TNF-
, CCR3, Eotaxin mRNA than that of control group. Conclusions YHJST on atopic dermatitis to atopic dermatitis NC/Nga mouse induced DNCB was incredibly effective.