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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
The Journal of Pediatrics of Korean Medicine
Journal Basic Information
Journal DOI :
The Association of Korean Oriental Pediatrics
Editor in Chief :
Volume & Issues
Volume 27, Issue 4 - Nov 2013
Volume 27, Issue 3 - Aug 2013
Volume 27, Issue 2 - May 2013
Volume 27, Issue 1 - Feb 2013
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A Case Report Regarding a Treatment Includes Lots of Different Version of Samchulkunbi-tang (蔘朮健脾湯) to Two Pediatric Patients Diagnosed as Sik-gan (食癎)
Kim, Eun Jin ; Min, Sang Yoen ; Kim, Jang Hyun ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 1~9
DOI : 10.7778/jpkm.2013.27.4.001
Objectives The purpose of this study is to report the cases of two pediatric patients diagnosed as Sik-gan (食癎), a kind of epileptic seizure thought to be caused by uncontrolled consumption of food, treated by formula variation of Samchulkunbi-tang (蔘朮健脾湯). Methods Two pediatric patients diagnosed as Sik-gan (食癎) according to traditional Korean medical terms were administered by variety of Samchulkunbi-tangs (蔘朮健脾湯) while correcting unhealthy eating habit. To measure the degree of the patients' process, the number and exact symptoms of seizure events, and gastrointestinal symptoms were recorded. Results The treatment of various Samchulkunbi-tang (蔘朮健脾湯) was not only extended remission period of seizure, but also improved gastrointestinal symptoms on both of the patients. Conclusions Pediatric patients who have past medical conditions for epileptic seizure as well as unhealthy eating habits or gastrointestinal malfunctions are prone to have a specific form of seizure called the Sik-gan (食癎). In this report, we have proven that variety of Samchulkunbi-tang (蔘朮健脾湯) can considerably be effective in improving the patients' gastrointestinal symptoms and preventing recurring seizure events.
A Review of Studies for Acupuncture Therapy of Attention Deficit Hyperactivity Disorder in Traditional Chinese Medicine
Kang, Mun Su ; Kim, Woo Kyoung ; Kim, Lak Hyung ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 10~16
DOI : 10.7778/jpkm.2013.27.4.010
Objectives The purpose of this study was to investigate the acupuncture therapy about Attention Deficit Hyperactivity Disorder (ADHD) in China. Methods We searched for the studies on ADHD at China National Knowledge Infrastructure (CNKI, http://www.cnki.net) from 2011.1 to 2013.8. Results Selected 12 studies were divided into 7 case reports and 5 control studies. 7 case reports reported significant improvements with acupuncture therapy in ADHD. 5 control studies reported results that the acupuncture therapy groups were similar or better than western medicine treatment groups. Frequently used acupuncture points were EX-HN23 (7 times), GV20
SP6 (6 times), G13
EX-HN1 (5 times). Conclusions There have been reported many ADHD clinical studies in China and these studies can be applied to the clinical practices in Korea.
The Study on Anti-obesity Effects of Mulberry Leaves Contained Herbal Mixture
Park, Jong Ik ; Kang, Kyung Ha ; Park, Eun Jung ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 17~30
DOI : 10.7778/jpkm.2013.27.4.017
Objectives This experimental study was designed to investigate the effects of Mulberry leaves contained herbal mixture (MLHM) on body weight, serum lipid level and adipocyte differentiation in high fat diet-fed obese mice. Methods Four-week old mice (wild-type C57/BL6) were used for all experiments. Cells were incubated with MLHM at the indicated concentration (0.04-4mg/ml) for 24h, and growth rate was assessed by MTT ((3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. 3T3-L1 preadipocytes were incubated in DMEM for 2 days with the indicated concentrations of MLHM, and on Day 6, the cells were fixed and the cellular lipid contents were assessed by Oil-Red-O staining. The expression of peroxisome proliferator-activated receptor
) and cytidine-cytidine-adenosine-adenosine-thymine (CCAAT)/enhancer-binding proteins
) as adipocyte-specific proteins were determined by real time RT-PCR and western blotting. In addition, body weight gain and serum lipid levels were measured in the mice with obesity induced by the high fat-diet for four weeks. Results Though MLHM did not show toxicity even at the concentration of 4mg/ml, MLHM significantly inhibited the differentiation of 3T3-L1 preadipocites in a dose-dependent manner. Also, MLHM significantly reduced the expressions of PPAR
in a dose-dependent manner. Furthermore, MLHM significantly reduced body weight gain and LDL-cholesterol contents in high fat diet-fed obese mice. Conclusions These results demonstrate that MLHM exerts anti-obesity effect in 3T3-L1 cells and mice with obesity by high-fat diet.
A Case Report of Oligoarticular Juvenile Idiopathic Arthritis with Oriental Medication and DMARDs & NSAIDs Tapering
Yoo, Chang-Kil ; Lee, Yun-Ju ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 31~38
DOI : 10.7778/jpkm.2013.27.4.031
Objectives This study is to report a case that has an effective result to oligoarticular type juvenile idiopathic arthritis patient with the oriental medicine treatment. Methods We treated the patient with an oriental medicine and tapered down with the DMARDs and NSAIDs. We followed up the laboratory blood tests every four or five months and throughout the experiment. Results The symptoms of oligoarticular type juvenile idiopathic arthritis were vanished and the patient maintained her good health condition with oriental medicine treatment after discontinued all Disease-Modifying Antirheumatic Drugs (DMARDs) and NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Her ESR, CRP levels were stable in normal and other blood test results were back to normal range. Her joint mobility and condition was back to normal. Now she is in clinical remission status. Conclusions According to the result, the oriental medicine treatment is considered to be effective on the oligoarticular juvenile idiopathic arthritis and further studies will be needed with more cases.
Effects of Rice Straw (RS) on Allergic Contact Dermatitis (ACD) Induced by DNCB in Mice
Park, Jem Ma ; Chae, Joong Won ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 39~49
DOI : 10.7778/jpkm.2013.27.4.039
Objectives In the theory of Korean medicine, rice straw (RS) has been used effectively as treatments for dyspepsia, diarrhea, enteritis, inflammatory epigastric diseases and various dermatitis. However, the theory has not been studied intensively yet about anti-inflammatory effects for human. This study was to investigate effects of RS for a treatment of allergic contact dermatitis (ACD) induced by 2,4-dinitrochlorobezene (DNCB) in mice. Methods In this experiment, effects of RS were investigated on changes in body weights, dorsum skin thickness, clinical aspects on the dorsum skin, spleen and body weight among these four groups; normal group (NOR), control group (CON), RS spread group (RSS) and RS spread and administer group (RSS+Adm). In addition, the effects on proliferations of splenocytes were also investigated in vitro and in vivo study. Results RSS group and RSS+Adm group showed increasing in body weights, diminished dorsum skin thickness and treated dermatitis on dorsum skin. In RSS+Adm group, spleen weights were lowered significantly compared to CON group. Conclusions In conclusion, these data suggest that RS can decrease symptoms of ACD significantly, and it shows the anti-inflammatory and immunosuppressant effect as well. Therefore, RS can be useful to treat patients with ACD.
The Effect of Herbal Medicine to Treat Digestive System Problem on the Children's Growth
Ko, Min Jung ; Baek, Jung Han ; Kim, Se Young ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 50~56
DOI : 10.7778/jpkm.2013.27.4.050
Objectives The purpose of this study is to evaluate the effect of the herbal medicine in treating digestive system problem on children's growth. Methods We studied 135 children who visited
oriental medical hospital to treat digestive system problem from March 2010 to February 2012. We measured their height and body weight on their first time visit and a year later. We compared them using the Growth Statistics Curve made by the Korean Association of Pediatrics, 2007. Results Generally, total children's average height and weight were significantly increased after the herbal medicine. The difference between the height and weight of treated children and the average height and weight was significant. Conclusions Herbal medicine to treat disorder of digestive system helped growth of children.
Comparisons of Effects of Biman-tang according to Administration Period in Childhood Obesity
Lim, Youngkwern ; Min, Seorim ; Kim, Heeman ; Hur, Kwang-Wook ; Lee, Hoon ; Lee, Jinsoo ; Kim, Hocheol ; Park, Jae-Woo ; Park, Hi-Joon ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 57~67
DOI : 10.7778/jpkm.2013.27.4.057
Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese (
Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI (
, respectively; p=0.003) and OI (
, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group (
, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.
A Case Report of Hands and Feet Hyperhidrosis
Park, Jem Ma ; Choi, Seon Wook ; Chae, Jung Won ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 68~76
DOI : 10.7778/jpkm.2013.27.4.068
Objectives The purpose of this study is to report the clinical effects of Korean medical treatment on the patient with hands and feet Hyperhidrosis. Methods A 9-year-old female patient, who was suffering from Hyperhidrosis on both hands and feet, was treated by Korean herbal medicine (Dangguisayuk-tang gami), acupuncture (Joksamri, Taegyue, Taechoong, Souboo hyul symmetricaly) and moxibustion on the abdomen (Joongwan). Also, VAS scales were used to check the improvement. Results About treating for two months, the patient's hyperhidrosis on both hands and feet were improved by Korean herbal medicine, acupuncture and moxibustion on the abdomen. Conclusions This study showed that Korean medical treatments can be an effective for the hands and feet Hyperhidrosis.
A Literature Study Based on Traditional Chinese Medical Journal about Treatment of Allergic Purpura - Based on Traditional Chinese Medical Journal -
Suk, Yun Hee ; Min, Sang Yoen ; Kim, Jang Hyun ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 77~86
DOI : 10.7778/jpkm.2013.27.4.077
Objectives Allergic purpura is frequent disease in children. The purpose of this study is to analyze traditional Chinese medicine treatments of Allergic purpura in children through traditional Chinese medical journal research. Methods 22 studies were selected based on title keyword "Allergic purpura" "Child" published in CAJ (China Academic Journal). The studies were about clinical effect, herbs, injections, treatments, and nursing in Allergic purpura in children. Results & Conclusions There are so many treatments studied on purpura in children based on CAJ. A Single or combination traditional Chinese medicine treatment is effective in Allergic purpura in children. Therefore, we need to study more about Allergic purpura in children and should make more clinical cases about it.
A Literature Study on Treatment of Infantile Anorexia Based on Chinese Medical Journals
Kim, Hee Yeon ; Seong, Woo Yong ; Kim, Ki Bong ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 87~98
DOI : 10.7778/jpkm.2013.27.4.087
Objectives The purpose of this study is to find a literature study of infantile anorexia clinical cases with Traditional Chinese Medicine (TCM) to utilize with Korean medicine treatment methods. Methods 5 TCM journals with the highest impact factors were searched and selected among the journals listed in www.cnki.net. The search keywords were, "Children's Anorexia", "Infantile Apositia", "Infantile Anorexia", "Anorexia Nervosa", and "child of anorexia". he search was limited to the publication date from 2000 to 2012. Results Total 20 studies were selected: Acupuncture (5), Herbal medicine (9), Complex Treatment (3), External Application (2) and Moxibustion (1). Among the Acupuncture related studies, 1 study tested the effect of Sifeng (EX-UE10, 四縫), 3 studies tested the effect of Sifeng (EX-UE10, 四縫) and other acupoints treatment together, and 1 study tested the effect of combination of other acupoints. In all these studies, the study groups showed better therapeutic effects compared to the control groups. The Herbal medicine related studies showed the improvement in appetite and weight as a result of Herbal Medicines treatment. Among the Complex Treatment related studies, 2 studies tested the effect of Acupuncture and Chiropractic co-treatment, 1 study tested the effect of Moxibustion and Herbal medicine co-treatment. In all these studies, symptoms of Infantile anorexia showed significantly improved. Other papers related to External Application and Moxibustion treatment were reported improving in appetite and had other the clinical effects as well. Conclusions Clinical studies testing the effect of TCM for the treatment of Infantile Anorexia have been conducted in small scales, and all the studies showed a certain level of symptom improvement of the patients in the study groups. These results implicate that the methods in Korean medicine can be highly potential treatment options for the treatment of Infantile Anorexia. Accurate and well-controlled studies in large scale would be required to prove the effect of Korean medicine for the treatment of patients with Infantile Anorexia.
A Literature Study on Treatment of Acupuncture and Acupressure for Myopia by Focusing Korean, English, and Chinese
Moon, Hye Yeon ; Cheon, Jin Hong ; Kim, Ki Bong ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 99~107
DOI : 10.7778/jpkm.2013.27.4.099
Objectives The purpose of this study is to obtain knowledge and views on treatment of acupuncture and acupressure for myopia. Methods The key words such as 'myopia, acupuncture', 'myopia, acupressure', 'refractive errors, acupuncture', 'refractive errors, acupressure' are used for the research through PubMed. Total 13 studies among the searched 66 were analyzed, except duplicated studies and have little relation to myopia or acupuncture and acupressure. Results Total 13 studies were selected: RCT (5), NRCT (3), UCT (3), Review (2). RCT had two studies on treatment by stimulating auricular acupoints, one study on a treatment by stimulating auricular acupoints and meridian acupoints, one study on a treatment to stimulate auricular acupoints with medication, and one study on electroacupuncture. In NRCT, two studies were on treatment to stimulate auricular acupoints with medication and only one study was on analysis of effect according to intensity of acupuncture. UCT had two studies on acupuncture, and one study on treatment to stimulate auricular acupoints. In Review, there were one study on introduction of Chinese eye exercises, and one study on systematic review for effectiveness and safety of acupuncture. Conclusions The effect on treatment of acupuncture and acupressure for myopia had mostly positive results. However, still not many researches were done to conclude this found. Also, the design of the experiment should be more accurate with systematically designed experimental group and control group.
The Study on Anti-obesity Effects of Gamiygin-tang Extract and Ferment
Chang, Sung Jin ; Min, Deul Le ; Park, Eun Jung ;
The Journal of Pediatrics of Korean Medicine, volume 27, issue 4, 2013, Pages 108~121
DOI : 10.7778/jpkm.2013.27.4.108
Objective This study was designed to investigate the effects of Gamiygin-tang (GY) extract (GYE) and fermented solution (GYF) on body weight, serum lipid level and adipocyte differentiation in high fat diet-fed obese mice. Materials and Methods High fat diet-fed obese mice and 3T3-L1 adipocytes mice were treated with GYE and GYF and obesity related markers were assessed. A cytotoxicity assay was carried out by MTS assay. Inhibitory effects of GYE and GYF on adipocyte differentiation were carried out by Oil Red O staining. The effects of GYE and GYF on the expression of adipocyte differentiation regulatory factors, peroxisome proliferator-activated receptor gamma (
) and CCAAT/enhancer binding protein alpha (CEBP-
) were measured by real-time reverse transcriptase-polymerase chain reaction. The effects of GYE and GYF on the expression of adipocyte differentiation regulatory factors were also determined in relation to protein production/protein levels by western blotting. The anti obesity effects of GYE and GYF were measured in high fat-diet induced obese mice. Various factors were measured from the serum of the high fat-diet mice. Results Though GYE did not show toxicity at the concentration of 1mg/ml, GYF showed toxicity at the concentration of 1mg/ml. The GYE at 0.1 and 1mg/ml inhibited the differentiation of 3T3-L1 cells, and the GYF also inhibited the differentiation of 3T3-L1 cells. The effect of GYE on adipocyte differentiation factors including PPAR-
was investigated and compared to the corresponding concentration levels of GYF. GYE and GYF both suppressed the RNA and protein levels of adipocyte differentiation factors. In the animal test both GYE and GYF reduced weight gain. GYE and GYF reduced blood cholesterol, TG and LDL levels. GYF better reduced blood cholesterol levels. Conclusions These results demonstrate that GYE and GYF exerts anti-obesity effect in 3T3-L1 cells and obese mice induced by high-fat diet.