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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of the Society of Cosmetic Scientists of Korea
Journal Basic Information
Journal DOI :
Society of Cosmetic Scientists of Korea
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Volume & Issues
Volume 32, Issue 4 - Dec 2006
Volume 32, Issue 3 - Sep 2006
Volume 32, Issue 2 - Jun 2006
Volume 32, Issue 1 - Mar 2006
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Effect of Antioxidation and Inhibition of Matrix Metalloproteinase-1 from Ligularia fischeri
Na, Young ; Kim, Jin-Hwa ; Sim, Gwan-Sub ; Lee, Bum-Chun ; Pyo, Hyeong-Bae ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 129~134
In this study, we examined the effects of antioxidant, lipid peroxidation inhibition and suppression of UVA-induced MMP-1 expression in human dermal fibroblasts. Ligularia fischeri extract showed free radical scavenging effect by 82.3% at 5 mg/mL and superoxide radical scavenging effect by 79.3% at 5 mg/mL in the kanthine/xanthine oxidase system, respectively. At the concentration of
, L. fischeri extract showed 97% inhibition on lipid peroxidation of linoleic acid. UVA induced MMP expression in human dermal fibroblasts was reduced 35% by treatment with
of L. fischeri extract. These results suggest that L. fischeri extract can be used for an anti-aging agent by antioxidation, lipid peroxidation inhibition and reducing UVA-induced MMP-1 production.
Herbal Extracts as a NF-kappaB Inhibitor
Park, Deok-Hoon ; Lee, Jong-Sung ; Jung, Eun-Sun ; Hyun, Chang-Gu ; Lee, Ji-Young ; Hur, Sung-Ran ; Koh, Jae-Sook ; Lee, Hee-Kyung ; Baek, Ji-Hwoon ; Yoo, Byung-Sam ; Moon, Ji-Young ; Kim, Ju-Ho ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 135~140
Nuclear factor-kappaB (NF-kappaB) is a critical transcription factor for maximal expression of many of the cytokines that are involved in the pathogenesis of inflammatory diseases. In this study, we found that 12 plant extracts among 200 plants, namely, Forsythia koreana, Capsicum annuum L, Mentha arvenis, Duchesnea chrysantha, Morus alba, Saururus Chinenis (Lour) Baill, Pine needle, Zingiber mioga (Thunb.), Roscoe, Houttuynia, Prunus yedoenis, Sasa quelpaertenis, significantly inhibited LPS- induced NF-kappaB activation in a concentration-dependent manner. Additionally, 12 plant extracts were found to have antioxidant activities in DPPH assay Therefore, we have attempted to determine whether 12 herbal extracts could inhibit the expression of cytokines possessing NF-kappaB promoter in their promoter regions. Consistently 12 herbal extracts inhibited LPS-induced production of TNF alpha and interleukin-8 (IL-8). These results show that 12 herbal extracts suppresses the production of pro-inflammatory mediators through the inhibition of the NF-kappaB signaling pathway, we suggest that 12 herbal extracts can be used as a anti-inflammatory and soothing agent.
The Effect of PMMA in the Color Tone of Color Cosmetics
Lee, Young-A ; Kim, Ju-Seub ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 141~148
This study is intended to analyze the impact of PMMA on color changes comparatively by making 2 types of cheek color items with red-color pigments: one containing PMMA, which is one of the recently developed circular polymers and used when producing color make-up items that have aero powder as the chief ingredient, and the other without it. To accomplish the purpose, we have reviewed literature on raw materials that have aero powder as the chief ingredient. Also, after making compounds of PMMA and pigments lot aero powder, such as Talc, Mica, OMC Talc As, Mica As, we examined them compared to those without PMMA using spectrophotometer, a questionnaire survey, and Digital camera. Besides, the particles were analyzed using SEM. As a result of the analysis, cosmetics containing PMMA represent more vivid and rich colors, putting on one's face softly. Since the entire specific surface area of PMMA is large enough to absorb oil evenly, it yields vivid and rich colors. But, Mica, one of natural pigments, shows a result as opposed to that of Mica As, one of silicon-compounded pigments, suggesting that pearl effect may possibly causes defused reflection. Based on these findings, it is expected that cosmetics will have more vivid colors, or improved color presentation, as well as the softer sense of touch when a circular polymer of PMMa is added to the manufacturing process of color make-up items.
Natural Oleosomes Loading Emulsion Technology -Loading Oleosomes as Delivery Systems for Improved Cosmetic Efficacies-
Tang, Diana ; Guth, Jack ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 149~152
Natural safflower oleosomes are small (
) spherical shaped "reservoir", inside which the seed stores triglycerides for use as a future energy source. The surface of the oleosome is covered with a high molecular weight (
KDa) oleosin protein which has been demonstrated to have emulsification properties. Traditionally, oleosomes from oil bearing seeds such as safflower were simply crushed to liberate the oil within. Our patented DermaSphere technology allows for the isolation of oleosomes in the intact state. Once isolated, these materials can be used in skin care formulations to deliver the emolliency, occlusivity, and anti-oxidant effects typically associated with safflower oil. However, because of the presence of the emulsifying oleosin protein covering the spherical oil body, oleosomes have self-emulsification property as well as can emulsify other oil phase in typical oil-in-water (O/W) emulsion. The oleosomes can literally serve as the entire non-active portion of the oil phase of a typical skin care product. Most importantly, natural oleosomes can be loaded with other oil-soluble active materials and can therefore be used as delivery systems for improved cosmetic efficacies. Oleosomes can be loaded with various actives, such as fragrances, vitamins, inset repellents, and UV chromophores. The loaded oleosomes can be utilized to either protect the active ingredients within the formulation itself or to allow for control release of those actives over time.
Synthesis of 2',4'-Dimethoxyflavone and Its Anti-pigmentation Effect
Lee, Bum-Chun ; Sim, Gwan-Sub ; Kim, Jin-Hwa ; Kim, Ki-Ho ; Lee, Hwa-Jeong ; Pyo, Hyeong-Bae ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 153~160
We synthesized 2',4'-dimethoxyflavone and investigated the effects on melanogenesis. To determine the effects as a whitening agent, various in uitro tests were performed such as free radical scavenging activity, melanin assay, tyrosinase activity and expression of tyrosinase, TRP-1 and TRP-2 (western blot and RT-PCR) in Bl6 melanoma cells. 2',4'-Dimethoxyflavone showed neither free radical scavenging activities against 1,1- diphenyl -2-picrylhydrazvl (DPPH) radical and inhibition of mushroom tyrosinase activity, 2',4'-dimethoxyflavone significantly inhibited melanin production in B16 melanoma cells. 2',4'-Dimethoxyflavone treatment (48h) suppressed the biosynthesis of melanin up to 27% at
and reduced tyrosinase activity up to 20% at
in B16 melanoma cells. 2',4'-Dimethoxyflavone was also able to significantly inhibit tyrosinase and TRP-1 expression in protein and mRNA level. These results suggest that 2',4'-dimethoxyflavone inhibits melanin biosynthesis at the level of enzyme activity and protein mRNA expression B16 melanoma cells. Therefore, 2',4'-dimethoxyflavone may be useful as a new whitening agent in cosmetics.
Preliminary Screening of Some Jeju Island Native Plants for Whitening and Antioxidant Activity
Yoo, Byoung-Sam ; Moon, Ji-Young ; Kim, Ju-Ho ; Hyun, Jin-Won ; Kang, Kyoung-Ah ; Koh, Jea-Sook ; Seo, Young-Kyoung ; Baek, Ji-Hwoon ; Park, Deok-Hoon ; Lee, Jong-Sung ; Jung, Eun-Sun ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 161~171
In this study, we investigated the whitening and anti-oxidant activity of 37 Jeju island native plants. The active ingredients of the plants were prepared by methanol extraction. Whitening activity of plant extracts was examined from the inhibitory effect of tyrosinase and the inhibition of melanin synthesis of the B16-F1 cell line. Their anti-oxidant activity was measured by electron donating ability of DPPH (1,1-diphenyl-2-picrylhydrazyl) and ROS (reactive oxygen species) scavenging activity in V79-4 lung fibroblast cells using DCF-DA (dichlorofluorescin diacetate). Cytotoxicity of the extracts on cell s based experiments was investigated by MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) assay. Also, the toxicity test using a rabbit and the human skin patch test were carried out for examining the safety of the extracts which showed the high whitening activity. It is interesting that the extracts of Lespedeza cuneata, Ligustrum lucidum (stem), Morus bombycis (stem) and Prunella vulgaris var. lilacina showed both potent whitening and anti-oxidant activities.
Effects of Lignan Compound of Sesame on LPS-induced Nitric Oxide Generation in Murine Macrophage RAW 264.7 Cells
Lee, Hwa-Jeong ; Son, Dong-Ju ; Kang, Myung-Hwa ; Lee, Bum-Chun ; Hong, Jin-Tae ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 173~180
Sesame (Sesamum indicum L.), one of the oldest oilseed crops, has been known to posses antioxidative and inflammatory effects. This seed contains lignan compounds such as sesamin, sesamol, sesaminol, sesaminol diglucosides (SDG), and sesaminol triglucosides (STG). Sesamin, a major lignan in sesame, displayed several biological activities including a protective effects against oxidative damage in the skin. In the present study, we investigated the effect of sesamin, sesamol, sesaminol, SDG, and STG, on nitric oxide (NO) induction and inducible nitric oxide synthane (iNOS) and cyclooxygenases-2 (COX-2) expression in lipopolysaccharides (LPS)-treated RAW 264.7 cells. The results showed that sesamol and sesaminol significantly inhibited NO generation but they were also cytotoxicity however, sesamin effectively inhibited NO production (
) without my cytotoxic effect in LPS-stimulated macrophage RAW 264.7 cells. In further study, it was founded that sesamin inhibited the expression of inducible nitric oxide synthase but not COX-2 expression. These results suggest that sesamin may be useful for improvements of the inflammatory diseases.
Antioxidative and Cellular Protective Effects of Jeju Native Plant Extracts against Reactive Oxygen Species (I)
Park, Soo-Nam ; Choi, Jung-Won ; Kim, So-I ; Jeon, So-Mi ; Kim, Jin-Young ; Yang, Hee-Jung ; Lee, Keun-Ha ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 181~191
In this study, we investigated the anti-oxidative, anti-wrinkle and whitening effects of 36 plant extracts collected from self-growing plants in Jeju island. Their anti-oxidant activities were measured by free radical scavenging activity using DPPH (1,1-diphenyl-2-picrylhydrazyl radical), reactive oxygen species (ROS) scavenging activities on ROS generated in
system using the luminol-dependent chemiluminescence assay, and cell protecting activities using the rose-bengal sensitized photohemolysis of human erythrocytes. In addition, the inhibitory activities of tyrosinase for whitening effect and elastase for anti-wrinkle were investigated. The results showed that the Rumex crispus (all grass) extract has the most significant free radical scavenging activity (
), Plantago asiatica and Rumex crispus extracts for the prominent ROS scavenging activity (
respectively), Rumex crispus (
), Machilus thunbergii leaf (216 min), and Celastrus orbiculatus (200 min) for cell protecting effects, Morus alba stem for the inhibitory activity on tyrosinse (94.8% at
), Rumex crispus (81.8% at
), Morus alba (74.6%), and Celastrus orbiculatus leaf/stem/flower (63.1%) for the activity on elastase. These results indicated that the extracts of Rumex crispus, Plantago asiatica, Machilus thunbergii leaf, Morus alba stem, Celastrus orbiculatus leaf/stem/flower could have the functional effects when they are added as ingredients in cosmetics. Thus, it is concluded that further experiments are needed to apply for cosmetic products.
Moisturizing and Anti-oxidation Effect of Astragalus membranaceus Root Extract
Jung, Taek-Kyu ; Kim, Mi-Jin ; Lim, Kyung-Ran ; Yoon, Kyung-Sup ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 193~200
We investigated the effect of moisturizing and anti-oxidation of Astragalus membranaceus (Astragali Radix) root extract with respective to growing districts and extract methods for the purpose of development of cosmetic ingredients. Astragalii Radix was collected in Jecheon, Jeongseon, Taebaek, and Yeongju in Korea and China as growing districts. Formononetin was determinated by HPLC method as one of the various active agents in Astragalus membranaceus root extract. The 75% ethanol extract demonstrated to be more effective than
-extracted one for a scavenging activities to DPPH radicals and reactive oxygens. The 75% ethanol extract showed
(50% scavenging concentration) of 2.162 mg/mL and 2.981 mg/mL in case of free radical scavenging activity test and reactive oxygen scavenging activity test, respectively Especially, free radical scavenging activity of isoflavonoids isolated from ethylacetate fraction was similar to scavenging activity of genistein. Astragalus membranaceus root extract of Jecheon district by sonicating extraction method was more effective in skin hydration compared with others.
Antimicrobial Effect of Ethanol Extract of Dryopteris crassirhizoma Nakai on Propionibacterium acnes
Yoon, Chang-Soon ; Kim, Hyun-Ju ; Lim, Hye-Won ; Choi, Shin-Wook ;
Journal of the Society of Cosmetic Scientists of Korea, volume 32, issue 3, 2006, Pages 201~208
Propionibacterium acnes have been recognized as pus-forming bacteria triggering an inflammation in acne. The present study was conducted to evaluate antimicrobial activities of Dryopteris crassirhizoma Nakai against these etiologic agents of acne vulgaris and application possibility as a cosmetic resource. D. crassirhizoma crude extract and hexane fraction was prepared and its anti-acne effect against Propionibacterium acnes was investigated with minimum inhibitory concentration (MIC) and paper disk diffusion method. The MIC of D. crassirhizoma crude extract and hexane fraction was 0.008 mg/mL and 0.001 mg/mL, respectively. This implies that D. crassirhizoma extract may be an efficient anti-acne ingredient for cosmetics, as a crude extract. The paper disk diffusion assay showed that its anti-acne effect was similar to that of triclosan. The cytotoxic effect of D. crassirhizoma extract was determined by a colorimetric MTT assay using HaCaT cell line and D. crassirhizoma extract exhibited lower cytotoxic effects. Finally, we examine the stability of D. crassirhizoma extract to temperature and pH. The D. crassirhizoma extract was very stable to high temperatures (
) and to wide pH range (
), suggesting its utilization for cosmetics.