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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Korean Journal of Plant Resources
Journal Basic Information
Journal DOI :
The Plant Resources Society of Korea
Editor in Chief :
Volume & Issues
Volume 6, Issue 2 - Nov 1993
Volume 6, Issue 1 - May 1993
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Notes on the genus Entoloma of Korea(VII)
Cho, Duck-Hyun ; Ryoo, Cheon-In ; Lee, Sang-Ree ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 1~12
Seven species of the genus Entoloma were collectted from the areas of Mt. Naejang National Park, Mt. Jiri National Park, Mt. Sunun Provincial Park and Mt. manduck from June, 1991 to September, 1991. These species were identified new to Korea : Entoloma subvile, E. bruneomarginatum, E. minutoalbum, E. subplanum, E. melleipes, E. perabidum, and E. pyrium.
STDIES ON ANTITUMOR AGENTS FROM HIGHER PLANTS
Itokawa, Hideji ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 13~23
To data, many types of compounds having antineoplastic activity have been isolated from higher plants, that is, alkalodids, terpenes, lignans, steroids and so on. Some of ther were isolated from Indonesian plants, Curcuma xanthorrhiza and Eurycoma longifolia. Bisaborane type compounds were compounds were isolated as antimeoplastic compounds againest Sarcoma 180A from C. xanthorrhiza, and quassinoids and euryrene type triterpenes from triterpenes from El longifolia. Casearines, a kind of diterpene, had been isolated as cytotxic components from Casearia sylvestris distributed in South America. RA series Cyclic hexapeptides isolated from Rubia akane and R. cordifolia also have strong antineoplastic activity against various types of tumors. Till now, 16 kinds of RA series compounds were isolated and named as RA-I~XVI. Moreover, monoglucoside of RA-V newly isolated from same plant. Many kinds of derivatives including natural RA compounds were tested for QSAR, and one of them, RA-VII was screened up as a most suitable substance as an antitumor agent. RA-VII(=RA 700) has strong cytotoxic activity against KB cells, P388 lymphocytic leukemia and MM2 mammary carcinoma cells. In some solution, three conformers of RA-VII were observed by NMR. It was discussed the relationship between conformation and activity. Total synthesis was already completed, but there is left room for improvement. Phase I clinical trials for RA-VII has been finished, then Phase II trials will be started before long.
Screening for Antitumor Efficacy fro the wild plants in Korea(II)
Lee, Sang-Rae ; Yoon, Eui-Soo ; Shin, Soo-Cheol ; Lee, Sang-Cheol ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 25~32
Many plants, which collected from Korea, were applied to antitumor and cytotoxic screeing tests against sarcom 180 a ascitec in mice, V-79 KB and P388 cultured cells. The results are summarixed as follows:1) The total packed cell volum method has been used for the antineoplastic screening for from natural higher plants in Korea. By this method, we have found out that the root, leaf and stem of Tripterygiu, regelii Spragne & Taketa having strong antineoplastic activity and also Rumex Japonicus Houtt. Eragrositis ferru-ginea Beauv. and Patrinia scabio-saefolia Fischer showed significant activity to anticancer tumor while cynanchum wilfordii Hemsley, and Rosa polyantha Sieb. et Zacc. showed slight activity to antitumor. 2) Among the 13 tested plants, the root and stem of Tripterygium regelii Spragne & Taketa and Amethystanthus excisus Nakai showed strong antitumor activity by the V79 cytotoxic cell screening test. 3) Twelve plants, which are glowing in mountainous area of Korea tested to anticancer activity. From the results, Eragrositis ferru-ginea Beauv., Angelica gigas Nakai, Geranium sibiricum L., Patrinia scabio-saefolia Fisher, Cynanchum wilfordii Hemsley, and Rubia akane Nakai have been proved to be anti-cancer plants by using P388 cell cultured method. 4) Tripterygiu, resgelii Spragne & Taketa, Eragrositis ferru-ginea Beauv., Patrinia scabio-saefoli Fisher, Cynanchum wilfordii Hemsley and Rasa polyantha Sieb. et Zacc., var. genuina Thunb. showed strong anti-tumor activity both total packed cell volume method and Cytotoxicity method.
The Present Condition of Production and Consumption of Medicinal Plants in Japan
Kawahara, Nobuo ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 33~44
The medicinal plants used traditional medicines are classified into two groups. The first group is formulary medicine which have been recorded on authorized books, for example, kampo drug in Japan. The second group is the fork medicines. These medicinal plants production is 165 billion yen(about 1.5 billion dollar) and which rate to to total pharmaceutical production is about 3% in 1990. The number of important medicinal plants treated in the market is 124 herbs from the total 364 herbs for kampo durgs(210 preparations kampo durgs) and other propritetary drugs (agents for common cold, laxatives, gastrointestional and so on). The production of the Ginseng and Bupleurum Root are increased about ten times in last twelve years(1976 or 1988). The 80% of these medicinal plants are imported from China, Korea and Southern Asian countries. Then the Pharmaceutical Affairs Bureau of Ministry of Health and Welfare published "The Guideline of Medicinal Plant for Cultivation" for a quality control and a stabilization supply of 80 herbs. The first part(1992) of the guideline reported 5 herbs; Coptis Rhizome, Rehmannia Root, Bupleur, Root, Japanese Angelica Root and Rhubarb, The next part will be published following 5herbs; Cnidium Rhizome, Safflower, Coix seed and Fruiet, Platicodon Root and Zedoary.
Isolation and Structural Determination of Antitumor Substanes from Natural Products using Bio-active Screening Tests
Takeya, Koichi ; Itokawa, Hideji ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 45~51
Many plants collected at Japan, China, Korea, Imdonesia and South America were applied to antitumor and / or cytotoxic screening tests against Sarcoma 180 ascites in mice and / or V-79, KB, P388 cultured cells. On the course of these screening tests, alcoholic extracts of Forsythia viridissima (Oleaceae), Eurycoma longifolia(Simaroubaceae), Rubia cordifolia and R. akane(Rubiaceae), Cissampelos pareira and Abuta concolor (Menispermaceae), Nardostachys chinensis (Valerianacese), Mansoa alliaceae (Bignoniaceae), Casearia sylvestris (Flacourtiacear), Maytenus ilicifolia (Celastraceae), Hedychium coronarium (Zingiberaceae), Croton palanostigma(Euphorbiaceae), Cocculus trilobus(Menispermaceae), Ginkgo biloba(Ginkgoaceae), Alpinia galanga and Cucculus zanthorrhiza(Zingiberaceae), Evodia rutaecarpa(Rutaceae), and Periploca sepium(Asclepiadaceae) showed significant activity and their active principles were clarified. In this paper, a few antitumor substances in above plants are introduced.
A Study of the Botanical Herb Medicine in Hyang-Yak Chip Seong Bang
Kang, Choon-Ki ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 53~75
This paper deals with Hyang-Yak Chip Seong Bang, which was made by Hyo-Tong Yu, Jung-Rye Noh and Yun-Duk Park by the order of King Sechong in 1431 and published in eighty-five volumes in 1433. This work includes on hundred three families and two hundred eighty-one species plants, and makes a comprehensive survey of past studies on some medical books. To publish this work, some specialists such as Jung-Rye Noh were sent to China and they made an exchange of opinions with some specialists of China to correct some facts. Cullen soryliforia and Trigonella foenumgraecum of Laguminosae were described as a subtropical plant or tropical plant which had not been produced in our country Also, it includes several anti-cancer plants such as Panax schinseng and Rubia akane that are very helpful to the treatment of diseases of adult people.
Basidiospore Development and Fine Structure of Entoloma squmiferrum
Cho, Duck-Hyun ; Lee, Sang-Rae ; Kwon, Sun-Bang ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 77~82
Basidia of Entoloma squamiferrum are developed from hymenium layer of cartor-shaped parabasidium. Apex of basidium is flat or depressed in the center. Although four sterigmata are developed, only two sterigmata are symmetrically swollen to two spores im certain basidia. It means that two sterigmata among four sterigmata are imfertil. A spore is formed by inflation of the apex of the sterigma. The apex of the sterigma is swollen into a paillaform and then turned into a penisform. It is swollen from a clubform into a globefrom. Six spots of the surfaces of globose spore are depressed with hilum axes. Finally the spore is cuboid, and then it is released from hilum.
Basidiospore Development and Fine Structure of Entoloma violaceobrunneum
Cho, Duck-Hyun ; Kwon, Sun-Bang ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 83~86
Four sterigmata of papillaform E. violaceobrunneum are developed from crator-shaped basidium. The apex of sterigma is swollen to a small globeform. And then it is swollen to a clubform. The clubform is again swollen to a ellipticalform, and then more than six spots of spore surfaces are ramdomly depressed with hilum axes. When the depression of surface of a elliptical spore is over, the spore is a heterodiametrical spore of multi-angular.
白頭山抗癌植物의 調査 白頭山抗癌植物遺傳資源의 調査硏究
Kim, Su-Cheol ;
Korean Journal of Plant Resources, volume 6, issue 1, 1993, Pages 87~98