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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Pharmaceutical Investigation
Journal Basic Information
Journal DOI :
The Korean Society of Pharmaceutical Sciences and Technology
Editor in Chief :
Volume & Issues
Volume 4, Issue 4 - Dec 1974
Volume 4, Issue 3 - Sep 1974
Volume 4, Issue 1_2 - Mar 1974
Selecting the target year
Studies on the Constituents of Kalopanax Nakai var typicum Nakai
Kim, Hack-Seung ;
Journal of Pharmaceutical Investigation, volume 4, issue 4, 1974, Pages 5~16
Liriodendrin, m. p.
as one of the antihypertensive components was obtained from the cortex of Kalopanax pictum. Acid hydrolysis of liriodendrin yielided liriresinol-A, -B and glucose. The stereochemistry of liriodendrin was established by the NMR spectrum of liriodrin octaacelate. The NMR spectrum of liriodendrin octaacetate showed that
of lirioresinol-B type occurs in nature.
Determination of Arsenic in Korean human liver and manganese, copper in Vitamin prepartions by neutron action analysis
Oh, Soo-Chang ;
Journal of Pharmaceutical Investigation, volume 4, issue 4, 1974, Pages 17~25
1. Neutron acivation analysis of arsenic contained in Korean human liver was studied in the view point of forensic chemistry, using 12 corpses. A sample of 1g was irradiated for 30 mins. in a neutron flux of
, followed by nitric-sulfuric acid digestion and then by Gutzeit separation. Radio activity was detected by it's scintillation counter. The arsenic content in the liver was found to be
. 2. A rapid and convenient method for the radiochemical determination of minerals by neutron activation analysis was established. After neutron irradiation to the standard soln. of Cu and Mn in pneumatic tube (neutron flux :
), Cu and Mn were determined by estimating the ratio of the widths under energy peak area in
. When the standard soln. of Mn and Cu is irradiated for 15 mins. to 18 hrs., recovery test shows that the relative errors are 5.1% and 4.5% for copper and manganese, respectively.
Studies on the Dissolution Rate of Prednisolone Powder and Tablets
Shin, Im-Sick ; Yong, Jae-Ick ;
Journal of Pharmaceutical Investigation, volume 4, issue 4, 1974, Pages 26~37
Having measured physical canstant and dissolution rate of prednisolone powder, and tablets, also particle size, particle number of powder disintegration, hardness, friability of prednisolone tablets and having also compared it's interrelationship. We obtained the results as following. 1) Dissolution rate of prednisolone powder was determinded cube root rule and: the slope
. 2) The tablet used in this study was fourteen kind of prednisolone tablets, two kinds of which were not conformity with prednisolone dissolution rate test of U.S.P. XVIII, but the rest of them were conformity with the same test (t60% was 4.3minute in average) 3) There was no significant interrelationship between disintegration, hardness, friability and dissolution rate of prednisolone tablet used in this study but we recognized the disintegration time was greatly influenced by the dissolution rate.
Effect of the alkyl sulfates to starilization of colloidal sulfurs containe in white lotion
Kim, Johng-Kap ; Lee, Sook-Kyung ;
Journal of Pharmaceutical Investigation, volume 4, issue 4, 1974, Pages 38~45
Sulfur had been used for the medical fields as fungacidal bacteriocides and gelatolytic agent from ancient B. C 700, their prepartiones contained the sulfur are restrict to freely medication, the restrutive reasones are the it's preparation stabilized sparing solubility, and limit to pharmaceutical development of colloidal sulfur-self. Anthors prepared white lotion, registered on U.S.P XIII from the colloidal sulfur, by the method midified buku zawa make the stabilized lotion by the various fatty alkyl sulfates, and the result obtained are as follows the suspending agents for stabilize to the colloidal sulfur are the fatty alcohol sulfates than natural clay on the imbibition appeareuce and usefulnss. The adequate quantities of stearic acid in lotion base are
percent for refluidity and pourability. The carbon numbers in alkyl radical used fatty alcohol sulfates as anionic surfactants are maxture of
about efficiency, as possible as, the electrolyte is removed from the white lotion.