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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Microbiology and Biotechnology Letters
Journal Basic Information
Journal DOI :
The Korean Society for Applied Microbiology and Biotechnology
Editor in Chief :
Volume & Issues
Volume 7, Issue 4 - Dec 1979
Volume 7, Issue 3 - Sep 1979
Volume 7, Issue 2 - Jun 1979
Volume 7, Issue 1 - Mar 1979
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Production of Single-Cell Protein from Methanol (Part 1) Isolation of Methanol-Utilizing Microorgamism and Composition of Medium
Microbiology and Biotechnology Letters, volume 7, issue 2, 1979, Pages 65~70
By the successive enrichment culture, methanol-utilizing bacteria of 213 strains were isolated from soil samples collected from various places. Among them one strain showing excellent growth was selected. The organism isolated was obligate methylotroph and identified as Methylomonas methanolica on the basis of its mophological and physiological characteristics of the cell. The medium have been to be collected for the maximum biomass productivity. The microorganism was capable of growing satisfactorily on a medium containing only methanol 0.8％ (v/v), ammonium sulfate 0.6％, magnesium sulfate 0.1％, phosphate salts, but did not require growth factor.
Production of Single-Cell Protein from Methanol (Part 2). Batch Fermentation and Continuous Fermentation by Methylomonas methanolica
Microbiology and Biotechnology Letters, volume 7, issue 2, 1979, Pages 71~74
The growth characteristics of Methylomonas methanolica YUFE 101, isolated from sewage samples, have been studied. conclusions of the study were; (1) Optimum cultivation pH and temperature are 6.3 and 32.5
respectively (2) The specific oxygen uptake rate was 332
ι/mg-dry weight/hr. (3) The maximum specific growth rate was 0.19 h
and celluar yield was 0.43 g-dry cell/g-methanol in batch culture, (4) The maximum biomass productivity achieved was 0.21 g-dry cel1/ι/hr at a dillution rate of 0.1 h
during continuous cultivation. (5) The contents of crude protein and total nucleic acid in the dry cell were 73 ％ and 12 ％ respectively.
Inhibitory Substance on the Snake Venoms Produced by Penicillium sp.
Seu, Jung-Hwn ; Yi, Dong-Heui ;
Microbiology and Biotechnology Letters, volume 7, issue 2, 1979, Pages 75~89
One strain of Penicillium sp. (175-66-B), isolated from soil, was able to produce a substance that has a strong inibition activity against the Agkistrodon and Trimeresurus venoms. In this experiment, the chemical and biological properties of the sample were investigated. As an inhibitory substance, it was effective to the proteinase, hemorrhagic and lethal factors of Agkistrodon and Trimeresurus venoms, and also effective to several fractions of the proteinases and hemorrhagic factors of Agkistrodon halys blomhoffi venom. Moreover, in the addition of prednisotone, it was more effective for the cure of the mouse envenomated with the venom amount of two fold of MLD
. This substance was very stable to the acid, alkali and heat. Its melting point was high enough to sublime at 222
without any decomposition. This sample was easily dissolved only in hot water, but not in several organic solvents except for a little dissolution in elate. It did not have the chelating activity. It had very strong specificity to the snake venoms. but its activity was depressed by the addition of zinc or cupric salts. This sample had no acute toxicity to the mouse. Its chemical formula was
with the molecular weight of about 392. It has two epoxy groups and four carboxyl radicals, but amino, nitrite and nitrate radicals, unsaturated bonds and aromatic ring were not detected. Theuchemical configuration of this sample was suggested to be;e;e;e;
Studies on the Microbial Utilization of Agricultural Wastes (Part 11) production of Ethanol and Xylose by Simultaneous Hydrolysis-Fermentation Using Cellulases and Yeast
Microbiology and Biotechnology Letters, volume 7, issue 2, 1979, Pages 91~95
Ethanol and Xylose were produced from cellulosic agricultural waste such as rice straw and corn cob by a single-step simultaneous hydrolysis-fermentation process utilizing semi-solid culture of Trithoderma as enzyme source and Saccharomyces yeast. By this process all the hexoses prduoced by the enzyme were converted to ethanol leaving pentoses which are not fermented by the yeast. By processing 50 g of rice straw, 18 ml of ethanol and 2.7 g of xylose were produced and 50 g corn cob produced 3.8 ml of ethanol and 10.8 g of xylose. Alkali-treatment of rice straw showed little effects on the productivities of ethanol and xylose. The possible reasons are discussed.
Isolation of Inhibitor against Mouse Carcinoma Cells from Streptomyces sp.
Microbiology and Biotechnology Letters, volume 7, issue 2, 1979, Pages 97~102
An actinomycete, AS-568, which produced an inhibitory substance against succinate dehydrogenase of Ehrlich ascites carcinoma and Sarcoma-180 cells of mouse, was isolated. The inhibitory activity was determined by SDI (Succinate Dehydrogenase Inhibition) method. The active substance was specific against carcinoma cells compared to normal cells in mouse; liver, kidney and brain. The inhibitory ratio was about 50％ after one hr treatment at 37
in vitro. Maximal productivity of active substance was recognized by 5 days culture in glucose-asparagine. The active component in cultural liquid was stable in neutral pH range and heat treatment reasonably, add it was recovered from precipitate by ammonium sulfate or non-dialyrable fraction in cellophane membrane as showing the behavior of high molecular substance.
Industrial Application of a Macrotetrolide Antibiotics
Ando, Kunio ; Nawata, Yoshiharu ;
Microbiology and Biotechnology Letters, volume 7, issue 2, 1979, Pages 103~112