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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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The Korean Journal of Pesticide Science
Journal Basic Information
Journal DOI :
The Korean Society of Pesticide Science
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Volume & Issues
Volume 7, Issue 4 - Dec 2003
Volume 7, Issue 3 - Sep 2003
Volume 7, Issue 2 - Jun 2003
Volume 7, Issue 1 - Mar 2003
Selecting the target year
Comparative molecular field analyses(CoMFA) on the growth inhibition activity of N-phenyl-3,4,5,6-tetrahydrophthalimide and N-phenyl-3,4-dimethylmaleimide Derivatives
Sung, Nack-Do ; Ock, Hwan-Suk ; Song, Jong-Hwan ; Lee, Yong-Gu ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 75~82
We discuss that the growth inhibition activities against root and shoot of rice plant (Oryza sativa L.) and barnyard grass (Echinochloa crus-galli) by N-phenyl-3,4,5,6-tetrahydrophthalimide (A) and N-phenyl-3,4-dimethylmaleimide (B) derivatives with changing substituents can be explained and predicted using comparative molecular field analyses (CoMPA) method. And the results show that the cross-validation value,
at three components and Pearson correlation coefficient,
were rice plant: shoot;
and barnyard grass: shoot;
, respectively. In addition, The activities of unknown compounds were predicted by CoMFA method. From the contour map of (A) derivatives, the selective factors to remove barnyard grass takes positive charge on the benzylic carbon atom (C27), negative charged carbon atom (C29) of meta position and steric bulky groups on the cyclic imino ring (C7-C8).
Fungicidal Activity of Domestic Plant Extracts against Six Major Phytopathogenic Fungi
Park, Il-Kwon ; Lee, Sang-Gil ; Park, Ji-Doo ; Shin, Sang-Chul ; Ahn, Young-Joon ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 83~91
Methanol extracts from 207 samples of 118 plant species in 44 families were tested for their fungicidal activities against six phytopathogenic fungi. Extracts of Thuja orientalis leaf, Cinnamomum loureirii leaf, Lindera erythrocarpa barks and leaf, Pinus koraiensis wood, Hovenia dulcis wood, Koelreuteria paniculata barks, Styrax japonica wood, Camelia japonica leaf and Cleyera japonica leaf showed very strong fungicidal activity against more than two phytopathogenic fungi at a concentration of 2000 ppm. As a naturally occurring fungicide, these plants could be useful as new fungicidal products against various plant diseases induced by plant pathogens.
Application and High Throughput Screening of DPPH Free Radical Scavenging Activity by Using 96-Well Plate
Choi, Jung-Sup ; Oh, Jung-Im ; Hwang, In-Taek ; Kim, Sung-Eun ; Chun, Jae-Chul ; Lee, Byung-Hoi ; Kim, Jin-Seok ; Kim, Tae-Joon ; Cho, Kwang-Yun ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 92~99
A 96-well plate was applied to determine the DPPH free radical scavenging activity using 107 plant-specific enzyme inhibitors and 100 unknown plant-originated extracts. The final optimum volume was
DPPH ethanolic solution at pH 7.8. In this condition, the radical scavenging activities were significantly increased by two known antioxidants consisting of ascorbate and a-tocopherol in a concentration-dependent manner. Among the 107 inhibitors, ampicillin and gallic acid showed 90.2% and 92.6% antioxidant activity at
, respectively, and these results were consisted with previous findings. In the tested 100 natural materials at
, antioxidant activity of AT-407 resulted in the highest of 90.1%, and 10 extracts including AT-388 and AT-443 showed over 70%. Our results suggest that the use of 96-well plate for determining DPPH free radical scavenging activity would be a suitable method to select antioxidant-like substances of both synthetic compounds and natural products.
Quantitative structure-activity relationships and molecular shape similarity of the herbicidal N-substituted phenyl-3,4-dimethylmaleimide Derivatives
Sung, Nack-Do ; Ock, Hwan-Suk ; Chung, Hun-Jun ; Song, Jong-Hwan ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 100~107
To improve the growth inhibitory activity against the shoot and root of rice plant (Oryza sativa L) and barnyard grass (Echinochloa crus-galli), a series of N-substituted phenyl-3,4-dimethylmaleimdes derivatives as substrates were synthesized and then their the inhibitory activities of protoporphyrinogen oxidase (220.127.116.11), protox were measured. The quantitative structure-activity relationships (QSAR) between structures and the inhibitory activities were studied quantitatively using the 2D-QSAR method. And also, molecular sharp similarity between the substrate derivatives and protogen, substrare of protox enzyme were studied. The activities of the two plants indicated that barnyard grass had a higher activity than the rice plant and their correlation relationships have shown in proportion for each. Accordingly, the results of SARs suggest that the electron donating groups as
group will bind to phenyl ring because the bigger surface area of negative charged atoms in the substrate molecule derivatives may increase to the higher the activity against barnyard grass. Based on the molecular shape similarity, when the derivatives and protogen, subsbrate of protox enzyme were superimposed by atom fitting, the similarity indices (S) were above 0.8 level but the correlation coefficients (r) between S values and the activities showed not good.
Comparative molecular field analysis (CoMFA) and holographic quantitative structure-activity relationship (HQSAR) on the growth inhibition activity of the herbicidal 3-phenyl-5-(3,7-dichloro-8-quinolinyl)-1,2,4-oxadiazole derivatives
Sung, Nack-Do ; Lee, Sang-Ho ; Song, Jong-Hwan ; Kim, Hyoung-Rae ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 108~116
A series of new quinclorac family, herbicidal 3-phenyl-5-(3,7-dichloro-8-quinolinyl)-1,2,4-oxadiazole derivatives as substrate were synthesized and their growth inhibition activity
against root and shoot of rice plant (Oryza sativa L.) and barnyard grass (Echinochloa crus-galli) were determined. And then comparative molecular field analysis (CoMFA) and molecular holographic quantitative structure- activity relationship (HQSAR) were compared in terms of their potential for predictiability. The statistical results were suggested that HQSAR based model had better predictability than CoMFA model. The selective factors to remove barnyard grass take electron withdrawing groups which can be created positive charge and steric bulky on the phenyl ring. Results revealed that the unknown 2,6-dichloro-substituent, U5 and 2,4,6-trichloro-substituent, U6(
=CoMFA: 1.18 & HQSAR: 1.82) were predicted as compound with higher activity and selectivity.
Modeling and Synthesis of Novel Hydroxyethyl 2-iminothiazolines
Hahn, Hoh-Gyu ; Nam, Kee-Dal ; Jeon, Jin-Ho ; Mah, He-Duck ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 117~122
Modeling and synthesis of novel hydroxyethyl 2-iminothiazolines were carried out through molecular modification of lead compound, 2-phenyliminothiazolines 1, for the purpose of development of new fungicidal agrochemicals. Oxygen atom of the hydroxyethyl group in 2-iminothiazolines 3 would locate in the proximity of the imino carbon at C-2 of 2-iminothiazoline moiety through neighboring group participation, and so that it would affect the biological activity of the molecule. Reaction of
-chloroacetoacetanilides 5 with hydroxyethylureas 6 gave 29 kinds of new corresponding hydroxyethyl 2-iminothiazolines 3 in high yields.
The Environmental Impact Quotient on Fruit and Vegetables Pesticides in Korea
Oh, Kyeong-Seok ; Lee, Byung-Moo ; Sung, Ha-Jung ; Oh, Hong-Gyu ; Ihm, Yang-Bin ; Kyung, Kee-Sung ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 123~130
The Environmental Impact Quotient(EIQ) has been used to organize the extensive toxicological and soil residue data available on some fruit vegetables pesticides into a usable form for field use. It addresses a majority of the environmental concerns that are encountered in agricultural systems including farm worker, consumer, ecological and environmental safety. The EIQ made use of the rating system by using the EIQ equation. The EIQ of pesticides registered for oriental melon was higher than that of other in terms of farm worker, consumer and environmental safety. Pesticides registered for red pepper showed highest EIQ in ecosystem. The EIQ decreased in order of insecticide> fungicide> herbicide> plant growth regulator. The environment Impact Quotient for the pesticides registered in fruit and vegetables decrease gradually.
Toxicological effects of pesticides on loach in rice paddy
Park, Yeon-Ki ; Park, Kyeong-Hoon ; Joo, Jin-Bok ; Kyung, Kee-Sung ; Kim, Byung-Seok ; Shin, Jin-Sup ; Ryu, Gap-Hee ; Bae, Chul-Han ; Lee, Kyu-Seung ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 131~138
A toxicological study of the pesticides for rice paddy to loach was conducted with iprobenfos 17% GR, diazinon 3 % GR, and butachlor 5 % GR to establish the field test method and their toxicological effects on loach under the actual field conditions. The type C of cage was more effective in the sense of a little stress from the cage. The nets for shading and for preventing the birds were necessary to maintain the water temperature and to prevent the predators. The cumulative mortality of loach exposed to iprobenfos 17% GR, diazinon 3% GR and butachlor 5% GR were 10, 55 and 22%, respectively, during 7 days of exposure. The averaged concentration of the pesticides in paddy water 2 days after application were 1.67, 0.22 and 0.26 mg/L, and mortalities were 7, 50 and 17%, respectively, representing the similar results with acute toxicity
Cultural and chemical approaches for controlling postharvest diseases of garlics
Kim, Yong-Ki ; Lee, Sang-Bum ; Lee, Sang-Seob ; Shim, Hong-Sik ; Choi, Inn-Hoo ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 139~148
The purpose of this study was to investigate damages of garlics occurred under cold storage and farmhouse storage condition, influence of cultural and environmental factors on storage spoilage of garlics, and to establish control strategies to reduce damages occurred under storage of garlics. Decays of garlics were highly related with cultural condition (paddy field or upland soil), ventilation, storage temperature and relative humidity, continuous cropping years, and harvesting stage. Early-harvested garlics were more decayed than late-harvested garlics. Garlics cultivated on paddy field were less decayed than ones cultivated on upland soil under farmhouse storage condition. The densities of Penicillium spp. and Fusarium spp. were higher on plot with long term continuous cropping cultivation history than on plot with short term continuous cropping cultivation history. However there is no relation between continuous cropping years and percent of decay of garlics. As a result of investigating influence of environmental factors on decay of garlics, P. hirsutum caused severe spoilage under high relative humidity condition, while F. oxysporum and Stemphyllium botryosum were not related with relative humidity. The three postharvest pathogens grew well above woe. In addition when P. hirsutum and S. botryosum were cultured for two months, they grew even at
. Except for environmental factors, wounds occurred through farming works. had an effect on storage spoilage of garlics. Garlics only hurt with a toothpick without inoculation of pathogens were decayed more severe than those inoculated with pathogens without wounds. Seven agro-chemicals showed highly suppressive effect were selected by measuring mycelial growth of three major pathogens of garlics on potato dextrose agar amended with 0.1% (v/v) of each fungicide. When they were foliar-sprayed on garlics 30 days before harvesting, it was confirmed that they suppressed storage spoilage of garlics. Also when garlics were sprayed with and drenched into the suspension of Benoram WP very after harvesting garlics, garlic damages by postharvest pathogens were reduced remarkably.
Selection of bactericides for control of potato Blackleg disease in Korea
Zhu, Yong-Zhe ; Park, Duck-Hwan ; Park, Dong-Sik ; Yu, Yong-Man ; Kim, Song-Mun ; Lim, Chun-Keum ; Hur, Jang-Hyun ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 149~154
Potato blackleg disease caused by Erwinia carotovora subsp. atroseptica has been a serious problem in Korea. It was previously reported that four mixtures [streptomycin (9.3 ppm) + copper oxide (171.6 ppm)/copper hydroxide (146.3 ppm), streptomycin sulfate (7.0 ppm)+copper oxide (171.6ppm)/copper hydroxide (146.3 ppm)] were effective for the control of E. carotovora subsp. atroseptica. in in vitro test. Using those four mixtures and two antibiotics [streptomycin (81.4 ppm) and streptomycin sulfate (61.3 ppm)], the effectiveness of control for E. carotovora subsp. atroseptica. was conducted in the field. Two antibiotics showed over 60% of control efficacy under different soil conditions, while mixtures of two antibiotics with copper compounds did not show any control effects on the infected seed potato. Two mixtures [streptomycin (27.9 ppm)+copper hydroxide (438.9 ppm), streptomycin sulfate (21.0 ppm) + copper oxide (514.8 ppm)] were effective in the control of potato blackleg disease on the infected potato plants under different climate conditions.
Synthesis of 2-Cyanoimino-1,3-thiazoline
Hahn, Hoh-Gyu ; Nam, Kee-Dal ; Park, Ik-Kyu ; Mah, He-Duck ;
The Korean Journal of Pesticide Science, volume 7, issue 2, 2003, Pages 155~158
2-Imino-1,3-thiazolines 1 show selective antifungal activity against pyricularia oryzae by new mode of action. A synthesis of novel 2-cyano-l,3-thiazolines 2 in which cyano moiety is substituted in imino group at C-2 of 1 is described. The lone pair electrons of sulfur and nitrogen as well as strong electron withdrawing cyano substituent in 1,3-thiazoline scaffold would effect the biological activity of 2-imino-1,3-thiazoline series. Regiospecific nucleophilic attack of thiourea 4 for
-ketoacetoacetanilide 3 followed by acid catalyzed dehydration gave 2.