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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Journal Basic Information
Journal DOI :
The Korean Oriental Medical Ophthalmology and Otolaryngology and Dermatology Society
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Volume & Issues
Volume 18, Issue 3 - Dec 2005
Volume 18, Issue 2 - Aug 2005
Volume 18, Issue 1 - Apr 2005
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A Literature Study about the Correlation between Genetic Studies on Atopic Dermatitis, Sasang Constitution, and Sasang Constitional Study on Atopic Dermatitis
Son, Jung-Min ; Choi, In-Hwa ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 1~9
Objectives: The objective of this study is to investigate the correlation between genetic studies on atopic dermatitis. sasang constitution, and sasang constitional study on atopic dermatitis. Methods: We retrieved data on PubMed for the papers of genetic study on atopic dermatitis. And for the papers on genetic study of sasang constitution and sasang constitional study of atopic dermatitis, we referred to papers have reported on domestic medical journal and domestic korean medicine journal. And we investigated correlations among the studies. Results: 1. There are two studies on genetic study on atopic dermatitis. One has been performed to find out genes related to atopic dermatitis by case-control study. The other has been to investigate the correlation between atopic dermatitis and the genes their functions were well-known. 2. Gene study on sasang constitution was performed to observe the distribution of the genes which is related with characteristics of sasang constitution, but there was no significant maldistribution of the genes. 3. There was no correlation between genetic study on atopic dermatitis and genetic study on sasang constitution. Conclusion & Discussion: In the Sasang constitutional study of atopic dermatitis, it seems that further studies on genes related to characteristics of skin, character affecting on behavior, and neurobiological difference among Sasang constitution are required as well as studies on distribution of genes related atopic dermatitis.
The Effects of Sanpunggosamhwan on the Allergic Contact Dermatitis
Nam, Bong-Soo ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 10~27
Objectives: To study the effectiveness of Sanpunggosamhwan(SGH) against Allergic Contact Dermatitis(ACD), the contact hypersensitivity assay, change of cutaneous shape, anti-allergic effect, anti-inflammatory effect, and the effect on skin barrier were observed. Methods: The 200g rats were divided into three groups of 15 rats. The first group is the Normal group which was applied Acetone olive oil only. The second group is the ACD group which has intentionally activated Allergic Contact Dermatitis by DNCB. The third group is the SGH group which was given medication of Sanpunggosamhwan extract after the induction of Allergic Contact Dermatitis by DNCB. Each group of rats was observed after 24, 48 and 72 hours. Results: I. With the result of contact hypersensitivity assay, at 24hours SGH group showed appreciably less ear swelling than ACD group. 2. Regarding general change of skin, SGH group showed less hyperplasia of epidermis, less damage of epidermis than ACD group. 3. Regarding the number of WBC, ACD group showed significantly less than normal and SGH group at 72 hours. 4. Regarding the number of RBC in blood, ACD and SGH group showed significantly more RBC than normal group at 24, 48, 72 hours. 5. Regarding the ratio of neutrophil in WBC, ACD and SGH group showed significantly high percentage than normal group at 24, 48 hours. 6. Regarding the ratio of lymphocyte in WBC, ACD and SGH group showed significantly high percentage than normal group at 48 hours. 7. Regarding the erythema, SGH group showed significantly more erythema than normal and ACD group at 48 hours. 8. Regarding the melanin, SGH group showed significantly less melanin than normal group at 24 hours.9. Regarding the skin hydration, SGH group showed significantly high value than and ACD group at 72 hours. 10. Regarding the skin pH, ACD group showed significantly high value than normal and SGH group af 24 hours. 11. Regarding the number of Total IgE, ACD and SGH group showed more Total IgE than normal. g개up at 24 hours. 12. At Electro microscope-morphologic changes of skin, the damage of epithelium was decreased and regeneration power of skin was increased in the SGH group. Conclusions: The Sanpunggosamhwan extract administration was effective on the mitigation of skin damage in rats with allergic contact dermatitis.
The Effects of Gudambopae-Tang on Changes of Cytokines in Allergic Rhinitis Model
Yang, Hee-Yeon ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 28~35
In order to investigate the effects of Gudambopae-Tang on allergic rhinitis, laboratory study about cytokines and OVA-specific IgE was perfomed in the present study. The results are summarized as follow; 1. IL4, IL-5 was increased in medicating group than control group. 2.
was increased in medicating group than control group. 3. total IgE and OVA-specific IgE was significant decreased in medicating group than control group, statistically significant. This study shows experimentally that Gudambopae-tang could reduce allergic reaction in allergic rhinitis. Advanced studies are required to investigate the mechanisms of herbal medicine in allergic rhinitis model.
The Effect of Tongkyu-tang on the Ovalbumin-inhalation Rat Model with Allergic Rhinitis
Jung, Jin-Young ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 36~50
Background and Objectives: Allergic rhinitis is an allergic reaction characterized by sneezingm itchy nose, mouth and throat, congestion and/or nasal discharge. The offending allergenes are usually pollens, molds, dust mites and animal allergen. Recently, the incidence of infectious nasal diseases tend to decrease. However, allergic rhinitis has increased and treatment in most cases has only deat with the symptom. Tongkyu-tang was composed of sixteen crude drugs. The Oriental Medical References mention therapeutic effects of Tongkyu-tang on nasal obstruction, watery nasal discharg. And Tongkyu-tang has clinically been used for the treatment of common cold, headache, sternutation, rhinitis etc. Speacially Tongkyu-tang is one of the most frequently used medical treatment for the allergic rhinitis. Experimental studies were conducted to investigate for the effect of Tongkyu-tang on the changes of neutrophil segment, lymphocyte, total IgE and nassal tissue in allergic rhinitis of ovalbumin-inhalation rat. Meterial and Methods: Fifteen Sprague-Dawley rats were divided into three group: normal group, control group, experimental group. To induce the allergic rhinitis in control group and experimental group, rats were sentitized intraperitoneally with 0.1 % ovalbumin solution 3 times at intervals of I week. Then intranasal sensitization was performed by diffusing 0.1 % ovalbumin solution 3 times at intervals of 2 days. After that time, rat in the experimental group were oral administration treated by Tongkyu-tang for 28 days. We observed changes in nasal tissue; changes in the number of white blood cell, red blood cell and total Ig E; also changes in the segment of neutrophil and lymphocyte in blood. And we observed the changes of AST, ALT of three group. We used anova test statistically. Result: The number of leucocyte remained unchanged between three group. The number of erythrocyte was increased in experimental group and control group when compared with the normal group. The segment of neutrophil, in blood was decreased in experimental group when compared with the control group but, that was not significant statistically(p<0.05). The promotion of lymphocyte in blood was significantly decreased in experimental group when compared with the Control group(p<0.05). Total IgE was decreased in experimental group when compared with the control group but, that was not significant statistically(p<0.05). The cilium be well preserved in experimental group: the nasal tissue in experimental group was similar to in the normal group. Congestion and expantion of grandular cell in nasal submucosa, hypertropy of epithelium in nasal mucosa, acid mucus in epithelium and neutral mucus in subepithelium were decreased in experimental group when compared with the control group. Effect of Tongkyu-tang on the liver function were also studies in rats. Treatment of Tongkyu-lang did not affected on AST and ALT. Conclusion: Considering the above experimental results, it is suggested that oral administration treatment using Tongkyu-lang, without worry about liver function injury, decreased response on an Animal model with Allergic Rhinitis.
A Clinical Analysis of Ophthalmology, Otorhinolaryngology & Dermatology
Jung, Soon-Young ; Seo, Hyung-Sik ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 51~61
We analyzed statistics study in 1394 patients, who had visited to the Dept. of dermatology, ophthalmology & otorhinolaryngology Hospital of Oriental Medicine Sangji University from July, 2003 to December, 2004. The results were as follows. 1. Distribution of ophthalmology, otorhinolaryngology and dermatology classification was 14.23% in ophthalmology, 13.92% in rhinology, 4.79% in laryngology, 23.05% in dermatology, 8.25% in otology, 2.14% in stomatology and 33.63% in other. 2. Ophthalmology group were 12.39% males and 14.16% females in 61years old over. In treatment term, opthalmology patients who had treated for 2 weeks within were 85.84%. Blepharism and asthenopia were the most common ophthalmologic disease. 3. Rhinology group were 18.10% males in 11-20 years old and 14.48% females in 10 years old within. In treatment term, rhinology patients who had treated for 2 weeks within were 70.59%. Rhinitis and sinusitis were the most common rhiniologic disease. 4. Otology group were 19.08% males and 16.80% females in 61years old over. In treatment term, otologic patients who had treated for 2 weeks within were 64.89%. Tinnitus and vertigo were the most common otologic disease. 5. Laryngology group were 10.53% males and 17.11% females 41-50 years old. In treatment term, laryngology patients who had treated for 2 weeks within were 85.53%. pharyngitis and abnormal pharyngolarylgeal region sensation were the most common laryngologic disease. 6. Stomatology group were 11.76% males in 31-40, 41-50 years old and 17.65% females in 61 years old over. In treatment term, stomatology patients who had treated for 2 weeks within were 82.35%. Stomatitis and labium spasm were the most common stomatologic disease. 7. Dermatology group were 11.75% males and 15.30% females in 21-30 years old. In treatment term, dermatology patients who had treated for 2 weeks within were 72.95%. Acne and urticaria were the most common dermatologic disease. 8. Other group were 8.99% males in 41-50 years old and 14.04% female in 61 years old over. In treatment term, other group patients who had treated for 2 weeks within were 69.29%. Bell's palsy and common cold were the most common other disease.
The Clinical Study of Fatigue Perceived by 33 Patients with Bell's palsy
Kim, Min-Ji ; Eom, Jae-Yong ; Ko, Tae-Hyun ; Hong, Seung-Ug ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 62~69
Objective: This study is to explore the various aspects of the fatigue perceived by patients with Bell's palsy Method: 33 patients who were diagnosed as Bell's palsy were sequentially interviewed and examined Results: The results were as follows 1. The mean average fatigue score of subjects was
: the physical fatigue revealed the highest value with a mean of
, followed by neurosensory fatigue with a mean of
, psychological fatigue with a mean score of
. 2. With the respect to the general characteristics of subjects, there were statistically significant differences in the patients' fatigue perception by age and the amount of sleeping time. Conclusions: We needed the further study about the relation between fatigue and Bell's palsy
Usability of Tympanometry in Oriental Medical Treatment of OME
Kim, Hee-Jeong ; Yoon, Hui-Sung ; Park, Owe-Suk ; Kim, Keoo-Seok ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 70~79
Background: Otitis media with effusion(OME) is one of the most common disease in childhood. Patient suffers from OME in many quarters. For example hearing loss, effects on speech, language, learning, behaviouralchanges etc. But the diagnosis of OME is difficult using only medical history and otoscopy. So, many other diagnostic tools are developed and tympanometry is one of them. When OME is treated by oriental medical Tx, tympanometry would be useful instrument. Objectives: To gain insight into the usability of tympanometry in F/U of OME treated by oriental medial Tx. Methods: Data was collected from 123 ears of 74 children who was treated by oriental medical Tx. Data includes sex, age, period of Tx, elapsed time to be improved, tympanograms and accompanied symptoms. The relationship between items was analysed by statistical methods. Results: There is no relationship between age, sex and period of Tx/elapsed time to be improved. When cough and phlegm is accompanied, the period of treatment and elapsed time to be improved are expanded. When improvement was seen on tympanogram, the period of treatment is expanded but the improvement was seen within 30days, the period of treatment is reduced. Conclusion: The application of tympanometry in oriental medical treatment of OME would provide us many informations about the status of patient so it will be helpful to predict the history of a case and to make a decision whether keep up treatment or not.
A Case Report of Facial Nerve Palsy in Herpes Zoster Oticus with Chronic Hepatitis B
Kim, Min-Hi ; Kim, Ja-Hye ; Yoon, Hwa-Jung ; Ko, Woo-Shin ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 80~85
A female visited the Dept. of Oriental Ophthamology & Otolaryngology & Dermatology, Dong-eui University with Facial Nerve Palsy in Herpes Zoster Oticus. She had been taking ill with chronic hepatitis B and taking western medicine. We treated a patient with only Oriental Medicine.(the herbal medication and acupuncture etc). Because she was afraid of herbal medicine -induced hepatitis, went through an examination about LFT profile regularly. The symptom of Herpes Zoster Oticus was improved and there was no abnormality in LFT profile. Through this case, we thought that it is possible to treat the other disease of the patient with chronic hepatitis using herbal medication without hepatotoxic hepatitis. But for the safety of patient and doctor in several case, we need to accumulate objective data about the side effect of herbal medications inducing hepatotoxic hepatitis.
A Case of Tolosa-Hunt Syndrome with Facial Palsy
Sim, Sung-Yong ; Um, Yu-Sik ; Hong, Chul-Hee ; Kim, Kyung-Jun ; Byun, Hak-Sung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 86~92
Painful ophthalmoplegia due to idiopathic granulomatous inflammation of the cavernous sinus/superior orbital fissure has been termed Tolosa-Hunt syndrome(THS). The syndrome is characterized by pain behind, above or around the eye, involvement of the cranial nerves which pass through the cavernous sinus, spontaneous remissions and exacerbations, and a favourable response to steroid therapy. There was the 56 years old man who suffered from painful ophthalmoplegia and facial palsy. The oriental medical treatment without steroids and analgesics reduced the symptoms of the patient remarkably during 5 weeks. There is few report that treat THS with oriental medical method. If more clinical trials like this are proved to be effective, we can expect that oriental medical treatment will be a good method in THS.
A Case of Vestibulopathy With Vertigo
Yu, Mi-Kyung ; Choi, Jung-Hwa ; Kim, Jong-Han ; Park, Su-Yeon ; Park, Yong-Ho ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 93~98
Vertigo occurs when there is conflict between the signals sent to the brain by various balance- and position-sensing systems of the body. Injury to or diseases of the inner ear can send false signals to the brain indicating that the balance mechanism of the inner ear (labyrinth) detects motion. Inner ear disorders, such as benign paroxysmal positional vertigo (BPPV), Meniere's disease, vestibular neuronitis, or labyrinthitis. Vestibular neuronitis is an inflammation of the vestibular nerve, which is located in your inner ear. In this case, She has vertigo occured suddenly and continued even when the person lies completely still. It may be accompanied by nausea and vomiting. She has taken herbal medication and treated by acupunture. Her symptoms become disappeared after 3 days and All most symptoms were disappeard. In conclusion, It is required to classify vestibulopathy into vestibular neuronitis or labyrinthitis. In this case we diagnosed her case as vestibular neuronitis. Her symptoms of vestibulopathy recovered fast by Korean traditional medical therapy.
?A Case Study of One Taeeum-person Who Has Tinnitus That is Diagnosed as Cold Turbid Phlegm in Middle Cho
Park, Yong-Ho ; Kim, Jong-Han ; Park, Su-Yeon ; Choi, Jung-Hwa ; Yu, Mi-Kyoung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 99~103
The tinnitus is a very common otorhinolaryngologic disease. But, we do not know the exact cause and the healing method of that. We have a case report of the patient who has both tinnitus during two years. He has also chest distress, chest pain, shoulder.neck pain, obesity. In Oriental Medicine, the cuases of tinnitus have diagnosed as the hepatic fire, phlegm-fire, heart fire, deficiency of the kidney, deficiency of vital energy and blood, and so on. In this study the patient classified by Sasang constitutional medicine, and the cuase of tinnitus diagnosed as cold turbid phlegm in Middle Cho, had a medical effects. And in the result, the other symptoms are reduced. So we report the healing process and result of this patient in this study.
A Case of Drug Eruption
Jee, Seon-Young ; Lee, Sang-Kon ; Lim, Jin-Ho ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 104~108
Drug eruption refers to an adverse effect which is unintentionally given rise to by dosage, injection, inhalation, suppository and ointment, etc. Maculopapular, urticarial, morbilliform, papulosquamous, pustular, and bullous morphologies may be encountered. Adverse drug reactions also can cause pruritus or dysesthesia unaccompanied by rash. We treated a patient suffered from maculopapular rash and pruritus with acupuncture, herb medication and wet dressing. After treatment we observed the improvement. Based on this study, it is considered that oriental medical treatment can be applied to the management of drug eruption.
Two Cases of Atopic Dermatitis
Shim, Eun-Ki ; An, Chan-Gn ; Du, In-Sun ; Hwang, Chung-Yeon ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 109~117
Atopic Dermatitis is chronic eczematous dermatosis which is related strongly to a family history of atopic disease and hereditary disposition. Its threshold of itching is low so that severe itching occurs and causes secondary eczema. The purpose of this study was to estimate the efficiency of oriental medical treatment and management on atopic Dermatitis. We studied 2 patients who visited Wonkwang University Kwangju Oriental Hospital Dept. of Dermatol. with atopic dermatitis from April 2004 to February 2005. We treated him with herb-medication, acupuncture, negative therapy, full spectrum visible ray therapy(by carbon arc). We used the ADSI(Atopic Dermatitis Severity Index) to assess the severity of atopic dermatitis. The grade of the severity of atopic dermatitis was lower only by the traditional chinese medical treatments and management. Considering the above result, more study is needed the factors of increasing severity of atopic dermatitis, and the clinical interchange or atopic Dermatitis between oriental medicine and western medicine.
Two Cases of Epistaxis
Jee, Seon-Young ; Lee, Sang-Kon ; Hwang, Sun-Yi ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 18, issue 2, 2005, Pages 118~123
Epistaxis is the condition which the blood comes out with the nose. It has been known that nasal bleeding happens with many reasons. In most cases, epistaxis is a slight illness, but sometimes, it leads to death because of longstanding or copious bleeding. First of all, to stop a hemorrhage is most important treatment for epistaxis, but the curative effect of oriental medical treatment for epistaxis does not become known well. We treated a patient suffered from epistasis with acupuncture, herb medication. After treatment we observed the improvement. Based on this study, it is considered that oriental medical treatment can be applied to the management of epistaxis.