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The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Journal Basic Information
Journal DOI :
The Korean Oriental Medical Ophthalmology and Otolaryngology and Dermatology Society
Editor in Chief :
Volume & Issues
Volume 22, Issue 3 - Dec 2009
Volume 22, Issue 2 - Aug 2009
Volume 22, Issue 1 - Apr 2009
Selecting the target year
Effect of Sopung-san Extracts on the Passive Cutaneous Anaphylaxis of Wistar Rats (Type I Allergic Dermatitis)
Ryu, Ji-Chul ; Lee, Jae-Geun ; Ku, Sae-Kwang ; Jee, Seon-Young ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 1~10
Purpose : The objective of present study is to detect the effect of Sopungsan aqueous extracts (SPS) on the passive cutaneous anaphylaxis (PCA; type I allergic dermatitis) Method : 500, 250 and 125mg/kg of SPS were orally administered 12 hr-interval before antigen challenge (total 4 times administered). PCA reactions were induced using rat anti-ovalbumin (OVA) serum contain IgE (titer 1:32) as sensitization and OVA as antigen challenge. 30 min after antigen challenge, the diameter of blue-dye spots (evans blue) and leaked amount of dye were observed with histology and histomorphometry at the PCA induced sites. In addition, serum total IgE and histamine levels were also observed by ELISA, respectively. The effects of SPS were compared with dexamethasone 1mg/kg treated rats in the present study. Results : As results of PCA reaction, vasodilation related increase of diameter of blue-dye spot and amount of leaked dye were observed with swelling and edematous changes in the dermis of PCA induced sites. However, these changes on PCA reactions were dramatically and dose-dependently decreased by treatment of SPS as compared with vehicle control. In addition, serum elevations of IgE and histamine were also dose-dependently inhibited by treatment of SPS as compared with vehicle control respectively. The effects of SPS 500mg/kg were similar to that of dexamethasone 1mg/kg in the present study. Conclusion : Base on the results of the present study, it is concluded that SPS has favorable effect on the PCA-induced allergic dermatitis, and SPS 500mg/kg showed similar favorable effects as compared with dexamethasone 1mg/kg. The present findings demonstrate that SPS can be effective for the prevention and treatment of allergic dermatitis.
Inhibitory Effect of Dendrobium moniliforme on NO and IL-
Production in LPS-stimulated Macrophages
Park, Ga-Young ; Bae, Chang-Hwan ; Park, Sun-Young ; Kim, Ji-Hee ; Ko, Woo-Shin ; Kim, Young-Hee ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 11~19
Effects of Eriobotryae Folium as Anti-Oxidant on HaCaT keratinocyte
Park, Yoon-Hee ; Kim, Jong-Han ; Choi, Jeong-Hwa ; Park, Soo-Yeon ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 20~35
Objective : The present study designed this study to investigate anti-oxidative effects of EF on HaCaT keratinocyte. Method : The present study measured the amount of polyphenoics and flavonoids, and also measured the levels of catalase, Ascorbate peroxidase (APX), SOD like activities and DPPH free radical scavenging activity. Then the effects of SB on viability and prolferation rates, and protective effects against oxidative stress induced by chemicals such as hydrogen peroxide and rotenone were also investigated. Results and conclusion : EF showed protective effect against cell death of HaCaT keratinocyte induced by rotenone and SNP significantly. In conclusion, these results suggest that EF may have anti-oxidantic action in human skin and also suggest that EF can be used as anti-aging agent.
The effect of Elastase inhibition and Tyrosinase by Rheum undulatum Stokes extracts
Lee, Jong-Chul ; Kim, Kyung-Jun ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 36~46
Objective : Recently, the demands for the effective and safe depigmentating and anti-aging agents of the skin have increased due to the medical, pharmaceutical and cosmetic reasons. The aim of this study is to search new materials from the traditional herbal medicines which inhibit the aging process of skin in vitro. Methods : herbal medicines(80% ethanol or water extracts) were screened for their inhibitory activities against elastase. Results : Rheum undulatum (final concentrstion 1 mg/ml) appeared over 30% of inhibition of elastase activity. so we are investigated anti wrinkle effects of Rheum undulatum look through MMP-1 inhibition activity. also Extracts of Rheum undulatum showed higher anti tyrosinase activity than arbutin (final concentration 1 mg/ml). Conclusion : These results suggest that herbal medicines could be strong potential sources of inhibition of anti-aging and whitening effects for the skin.
Pathways Analysis of Gleditsia spina Extract on Changes of Gene Expression in Human Melanoma cells
Kim, Bu-Yeo ; Lim, Se-Hyun ; Lee, Byoung-Ho ; Lim, Chi-Yeon ; Kim, Yong-Seong ; Cho, Su-In ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 47~62
Glenditsia spina (GS) can resolve carbuncle, relive swelling, dispel wind and destroy parasites. For these reasons, GS has been widely used as dermatologic agent clinically. In this study, the specific pathways of anti-proliferative effect of GS on human derived melanoma cells were identified. The molecular profile was measured using microarray technique to identify up- or down-regulated genes in SK-MEL-2 cell line. Pathway analysis was done by listing percentage of pathway involvement, and the represented pathways were obtained from KEGG. The transcription factor binding sequences were obtained by Transfac database. By the promoter analysis, up-regulated genes by GS were mainly associated with MAPK, Regulation of actin cytoskeleton, Wnt, Focal adhesion and Long term potentiation pathway. Down-regulated genes by GS were mainly associated with MAPK and Antigen processing and presentation pathway. And some of the transcription factors like Sp1 and NF-Y in up-regulated genes and Oct-1 in down-regulated genes by GS also identified.
Anti-inflammaory effects of the MeOH extract of Gentianae Macrophyllae Radix in vivo
Cho, Hwi-Chang ; Jung, Ho-Jun ; Lee, Jae-Geun ; Jo, Mi-Jeong ; Jee, Seon-Young ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 63~70
Objectives : The present study was examined to evaluate the anti-inflammatory effects of the Gentianae Macrophyllae Radix MeOH extracts (GMR) in vivo. Methods : The effects of GMR on anti-inflammation were measured by production of NO, TNF-
(Tumor Necrosis Factor-alpha) and IL-
), IL-6 in Raw 264.7 macrophage cells stimulated with LPS. Results : 1. All concentrations of GMR(0.10 mg/ml) had no significant cytotoxicity in Raw 264.7 cell during the entire experimental period. 2. The level of NO and iNOS in culture medium was dramatically increased by LPS application. However, these increases were dose-dependently(0.03 and 0.10 mg/ml) attenuated by treatment with GMR. 3. All concentrations of GMR significantly inhibited the production of IL-
in Raw 264.7 macrophage cells stimulated with LPS. Conclusions : These results provide evidences that therapeutic effect of GMR on heat syndrome, especially due to the acute inflammation, are partly due to the reduction of some of inflammatory factors by inhibiting iNOS and COX-2 through the suppression of
. Moreover, it suggests that the mechanism of action of GMR comes from the suppression of inflammatory mediators, such as NO, PGE2 and pro-inflammatory cytokines.
Anti-inflammaory effects of the MeOH extract of Humulus japonicus in vitro
Hwang, Sun-Yi ; Jung, Ho-Jun ; Jang, Woo-Seok ; Jo, Mi-Jeong ; Kim, Sang-Chan ; Jee, Seon-Young ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 71~79
Objectives : The present study was examined to evaluate the anti-inflammatory effects of the Humulus japonicus MeOH extracts (HJE) in the carrageenan-induced paw edema model in rats. Methods : The effects of HJE on anti-inflammation were measured in the carrageenan-induced paw edema model in rats and infiltrated Inflammatory Cells. Results : 1. HJE (1.0 g/kg) and dexamethasone effectively inhibited paw edema measured 1~4 h after carrageenan injection. HJE (0.3 g/kg) effectively inhibited paw edema measured 1, 3, 4 hr. 2. In histopathological study in rats, 1.0 g/kg HJE and dexamethasone effectively inhibited the increases of hind paw skin thicknesses and inflammatory cell infiltrations induced by carrageenan treatment. But quite similar histopathological changes were detected in 0.3 g/kg HJE treated group as compared with carrageenan control.
The Clinical Tests for Treatment Improvement Comparison in Myopia between Eye Acupuncture Massage Machine (NURIEYE-1) and Acupuncture
Kim, Mi-Bo ; Kim, Kyu-Kon ; Hong, Sang-Hun ; Ko, Woo-Shin ; Yoon, Hwa-Jung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 80~94
Objective : The purpose of this clinical research is the investigation of the effects between acupuncture group(control group) and NURIEYE-1 group (experimental group) in myopia Methods : Comparison clinical study was conducted with the randomly arranged 32 patients for acupuncture group(control group) and NURIEYE-1 group(experimental group). For effectiveness evaluation, eye sight test, MQOL and DITI were tested three times with visits for every 4 weeks. With SAS, Statistical analysis was performed by using paired t-test and two sample t-test. Statistical significance was achieved with less than 5% probability (p<0.05). Result : 1. There was no significant effect from the eye sight comparison between the two group. We had improved results in average with MQOL, however, there was no statistical significance. Though there was also no significant result with DITI average comparison between two group, we witnessed significant effect in some part of MQOL. 2. Nevertheless Periodical comparison test showed weak significance with eye sight and DITI, significant effect was found in some part of MQOL. 3. With periodical comparison tests, there were significant effects in eye sight, MQOL and DITI with the experimental groups and control groups, respectively. Conclusion : There was no significant eye sight improvement. However, with acupuncture point stimulation, we think there are some positive effects for the relaxation of excessive stress in eyes.
The Study on Pharmacokinetics According to the Administration Route
Park, Min-Cheol ; Kim, Hwan-Yeong ; Jo, Eun-Hee ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 95~107
Objective : The purpose of this study is to search for more effective administraion route of herbal medicine. Methods : Pharmacokinetic issues with the methods in experimental papers, which deal with finding the effectiveness of two or more administration routes of herbal medicine, searched from KERIS, KSI, KISTI and KTKP, have been analyzed by, first, categorizing the papers and comparing the validity of administration routes. Results and Conclusions : 1. Upon comparing in total of 24 papers on the basis of each administration route, per oral(PO)-herbal acupuncture(HA) was most superior in terms of number in that there were 13 cases and PO-per rectal(PR) was next superior in that there were 5 cases. PO-per dermal(PD)-inhalation therapy(IT), PO-IT and PO-PR-HA had 3, 2 and 1 cases respectively. 2. Out of the total 24 papers which compares different administration routes, 16 of them were pharmacokinetically appropriate, whereas, the remaining 8 were pharmacokinetically inappropriate. 3. Comparisons were made between PO-HA, PO-PR, PO-IT, PO-PD-IT and PO-PR-HA routes. However, none of them was not particularly effective regardless of the administered medicine or target organ. 4. No route was particularly effective against a particular drug target as a result of comparing damaged liver, asthma, endometriosis and anti-inflammation. 5. In the case of Injinhotang in medicine comparison, HA tended to be more associated with hepatotoxicity over PO. However, Cordyceps Militaris Mycelia, Gagamsohaphyangwon and Hongdeungtang showed no prominent effective administration route.
The Study on Atopic Dermatitis Papers Published in the Journal of Korean Oriental Ophthalmology & Otolaryngology & Dermatology
Seo, Min-Su ; Kim, Kyung-Jun ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 108~121
Objective : This study was carried out to analyze and understand the trends of Atopic dermatitis papers Published in the Journal of Korean Oriental Ophthalmology & Otolaryngology & Dermatology(JKOOOD) Methods : We have reviewed 43 articles of atopic dermatitis which were published in JKOOOD during 1988-2008. All the papers are classified into three categories; original article, review article and case report. Results : 1. The number of journals associated with atopic dermatitis is 43 papers: 16 original articles(16/43%), 16 case reports(16/43%), 11 review articles(11/43%). 2. Classification of 16 original articles in terms of methodology: 11 experimental studies(11/16%), 5 descriptive studies (5/16%), 0 analytic studies(0%). 3. Classification of 16 case reports in terms of the number of patients: 1 person(8/16%), 2 persons(3/16%), 3 persons(2/16%). Conclusions : In this study, we analyzed the trends of Atopic dermatitis papers Published in the Journal of Korean Oriental Ophthalmology & Otolaryngology & Dermatology during 1988-2008. It is needed to adopt the qualitative methods of evaluation in order to develop a level of evidence.
A study on 'Keo-Bu-Saeng-Gi'
Seong, Eun-Jin ; Kim, Hwan-Yeong ; Choi, Byeong-Seon ; Lee, Ho-Seop ; Yu, Hyeon-Ju ; Park, Seon-Gyu ; Choe, Jae-Hwan ; Lee, Yun-Gyeong ; Jo, Eun-Hee ; Park, Min-Cheol ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 122~131
Background and Objective : Keo-Bu-Saeng-Gi(去腐生肌) is the word meaning wound healing process of the skin disease. This study introduces the theory of Keo-Bu-Saeng-Gi that can be used for not only skin disease but also for rejuvenation, beauty care. Methods : We searched oriental literatures and reports related with Keo-Bu-Saeng-Gi(去腐生肌). Result and Conclusions : Many oriental literatures refered to Keo-Bu-Saeng-Gi(去腐生肌) as a wound healing mechanism of the skin disease. Wound healing is very important for skin disease and rejuvenation. We can use this theory of Keo-Bu-Saeng-Gi(去腐生肌) for skin care.
A Literature Study on the External Treatment of Seborrheic Dermatitis
Lee, Seon-Yong ; Jung, Jae-Ho ; Seo, Hyung-Sik ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 132~144
Objectives : The object of this literature study is to investigate the external treatment of seborrheic dermatitis. Methods : We have selected data related to the external treatment of seborrheic dermatitis on the literature of Oriental medicine. And we analyzed the study. Results : 1. The external treatment of seborrheic dermatitis is fundamental treatment. There are several external treatment, these are paint-treatment, shampoo-treatment and pillow-treatment. 2. Prescription used in external treatment of seborrheic dermatitis is Yungi-go(潤肌膏), Okgi-san(玉肌散), Yongnoe-go(龍腦膏), Johyub-tang(皂莢湯). 3. Herb used in external treatment of seborrheic dermatitis is Angelicae dahuricae Radix(白芷), Lysimachia foenumgraecum Hance(零陵香), Veratri Nigri Rhizoma Et Radix(藜蘆), Cannabis Fructus(大麻). Conclusions : Through literatual Study, we basically understood the external treatment of seborrheic dermatitis. In the study of external treatment, it seems that further clinical studies on seborrheic dermatitis treatment.
The Effects of Traditional Oriental Hair Care Products on Alopecia
Lee, Jae-Geun ; Lee, Jin-Sang ; Park, Hyun-Jin ; Jung, Ho-Jun ; Ha, Il-Do ; Cho, Won-Joon ; Jee, Seon-Young ; Kim, Mi-Ryeo ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 145~152
Objectives : The aim of this study was conducted to test alopecia by external application with traditional oriental hair care products. Methods : A total of 20 males who visited Daegu Hanny Oriental Medical Center from December 15th, 2007 to September 30th, 2008 were included in this study. In this study, they were treated with the hair care products(shampoo, hair tonic) containing herbs. For 12 weaks hair density and hair thickness content were measured by Folliscope 2.5. Comparative analysis result between before treatment and after treatment was checked. And satisfaction after using shampoo, hair tonic was checked. Results : Change of hair density and hair thickness between before treatment and after treatment (4, 8, 12 weeks) showed significant changes(p<0.05). Comparative analysis result between before treatment and after treatment showed significant changes(p<0.0001). Satisfaction after using shampoo, hair tonic was near good. Conclusions : Considering the above results, we have concluded that hair care products containing herbs have the remarkable effect on alopecia.
A Study of Clinical features and classifications of alopecia patients in Korean medicinal clinic
Lee, Tae-Hoo ; Moon, Jung-Bae ; Jeong, Jee- Haeng ; Leem, Kang-Hyun ; Kim, Hee-Taek ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 153~166
Objectives : This study was planed to evaluate clinical status of the alopecia patients who had visited Korean medicine clinic. And the result from this study would provide a standard in Korean medical diagnostic and classification method of alopecia. Methods : Clinical records of 183 patients with alopecia seen from January 2004 to April 2005 at Korean medical clinic was examined. They were classified into 4 different types according to chief complains besides alopecia by 2 Korean medical doctors. Results and conclusions : We made clinical analysis of patients of alopecia from January 2004 to April 2005. Among the alopecia patients who visit Korean medical clinic, people age between 20 and 30 had high ratio. The duration from the recognition of initial hair loss to the time of the first visit to the Korean medical clinic was less than 12 months in 20.8%(38/138), and less than 60 months in 72.2% (132/183). The condition of alopecia was more worse than other alopecia patients who visit the west medical clinic. Also the ratio with increased temperature of face or scalp is chief complaint except alopecia in alopecia patients was high in men and the ratio with dysfunction of digestive system or chronic weakness was high in women. Among the incidence of alopecia, the androgenic alopecia was most in number; 43.7%(80/183) and the sex distribution showed 83 men and 100 women.
The Clinical Observation of Bell's palsy sequela
Won, Jae-Sun ; Chou, Ching-Yu ; Cho, Ah-Reum ; Kim, Chang-Hwan ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 167~177
Objective : Bell's palsy is common and has many clinic study. but bell's palsy sequela is not enough study until now. So this study was evaluated bell's palsy sequela, catamnesis, demonstrator and herb. Methods : From December 2007 to November 2008, patients who visited Dong-seo Oriental Medicine ENT. A clinic study was done on patient who were diagosed bell's palsy, onset 2months over when first visited OPD and treated 3weeks over in Dong-seo Oriental Medicine Cental. To evaluate grade of paralysis, House-Brackman Scale was used. We classified period of improving, sequelas symptom except of facial muscle paralysis, Oriental Medicine diagnosis and herb. Results & Conculsion : 1. The distribution of sex : male 38.88%, female 61.11%. The distribution of age was presented that forty to fifty was the most in 10case(55.55%) 2. The distribution of the region of facial palsy : Rt(55.55%), Lt(44.44%) 3. In distribution of period of first HB-Scale improving : 1~2month was most in 10case(55.55%) 4. In distribution of symptom except of facial muscle paralysis : Dryness of eye 33.33%, Tearling 22.22%, Facial hypoesthesia 22.22%, Mastoid pain 22.22% 5. The distribution of demonstrator : Gi Deficiency and Deficiency of Both Gi and Blood was most in 11case(50%) 6. The distribution of treatment : Palmul-tang and Bojungikki-tang was the most herb in 6case(33.33%) and only acupuncture treatment and rehabilitation treatment was 5case(27.77%).
Comparison of Ambulatory Care with Hospitalization for a Severe Atopic Dermatitis Patient
Yu, Seung-Min ; Yun, Young-Hee ; Son, Byeong-Kook ; Choi, In-Hwa ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 178~187
Background : Atopic dermatitis is chronic exzemaous dermatitis and the recurrence rate of atopic dermatitis is high. Many patients are suffering from pruritus. Objective : This study compared ambulatory care with hospitalization for atopic dermatitis treatment of one patient, and investigated the effect of Oriental medicine program for atopic dermatitis patients during short term hospitalization. Method : We treated a 5 year-old boy with uncontrollable atopic dermatitis by ambulatory care and hospitalizaion. Herbal medication and herbal dressing was done samely during ambulatory care and hospitalization. Intensive life management, education for compliance was done only during hospitalization. Results : Even though he had been treated for 5 months by ambulatory care, he still suffered from severe itching, erythema, oozing and insomnia. Admission duration was 10 days. During admission, the SCORAD scores and subjective scores were decreased rapidly. Conclusion : We concluded that effects of the treatments can be different due to compliance of the patient and in that view the short term hospitalization program could be more helpful than ambulatory care for uncontrollable atopic dermatitis patients.
The literatual Study on the etiology of dry eye syndrome
Yoon, Seong-Sik ; Seo, Hyung-Sik ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 188~195
Objective : The object of this literatual study is to investigate the etiology of dry eye syndrome Methods : We have selected data related to etiology of dry eye syndrome on the literature of Oriental Medicine. And we analyzed the study. Results : Treatment and etiology concerning dry eye syndrome derived diverse opinion according to medical era and practitioner. It was a good opportunity to speculate the etiology and similar symptoms of dry eye syndrome. Conclusions : Through literatual Study, we basically understood the etiology of dry eye syndrome. In the study of the etiology, it seems that further clinical studies on treatment of dry eye syndrome via oriental medicine.
A Clinical Report on 39 Urticaria Patients Treated With The Ko-Bang(古方)
Tark, Myoung-Rim ; Kim, Mi-Bo ; Byun, Seok-Mi ; Ko, Woo-Shin ; Yoon, Hwa-Jung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 196~207
Objectives : This study was designed to investigate the chronical features of urticaria and the effects of urticaria treatment with Ko-Bang(古方). Methods : We treated 39 patients for urticaria with Ko-Bang(古方), who visited to care urticaria at the Dept. of Dermatology Oriental medical hospital Dong-eui university from Jan, 2008 to Sep, 2009. This study was assessed using the chart analysis and the follow-up survey by telephone. Results & Conclusions : 1. 39 outpatients were surveyed, who were 20 males and 19 females. And patients who were ages 21-30 were the largest group, 11(28.21%). Among the 39 patients, acute urticaria patients were 8(20.5%), chronic urticaria patients were 31(79.5%), and contraction of a disease period between 6 weeks with 3 months was 17.9%. 2. The causes of urticaria were measured unknown 37.5%, foods 37.5%, drugs 25% in acute and unknown 35.5%, a change of temperature 29%, foods 16% in chronic. And suspected provocation factors were measured unknown and foods each 12 cases. The most of accompanied symptoms was itching sign(34 cases), the second most was self-conscious fever(10 cases). 3. Out of treat prescription(Ko-Bang,古方), Injinho-Tang(茵蔯蒿湯) was used most in 5 cases, Daehwanghwangryunsasim-Tang(大黃黃連瀉心湯), Hwangryun-Tang(黃連湯), Daesiho-Tang(大柴胡湯) were used in each 4 cases, Galgeun-Tang(葛根湯), Chijadaehwangsi-Tang(梔子大黃豉湯), Sosiho-Tang(小柴胡湯) were used in each 3 cases, Gaemagakban-Tang(桂麻各半湯), Chijasi-Tang(梔子豉湯),Oryeongsan(五笭散) were used in each 2 cases. 4. When the processes of treatment were classified by one poison(一毒), there were the 19 cases (48.7%) which was caused by Bun(煩), the 12 cases(30.8%) by Water(水) and the 4 cases(10.3%) by Gyur(結).
A Literature study on the external treatment of Nasal Polyps
Han, Na-Young ; Seo, Hyung-Sik ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 208~219
Object : Understanding the importance of the external treatment of nasal polyps and let know the necessity of development of the effect of herb medicine to use in these days. Method : I investigated about 12 oriental medical texts which recorded the external treatment of nasal polyps. I separated them to three part (prescription, herb medicine, the way of making the external application) and check the frequency. Also compared the external treatment of oriental medicine and western medicine. Result : 1. Prescription: There are 48 prescriptions -Nyosasan is used 4 cases, Gwajungsan is used 2 cases and others only 1 case each. 2. Herb-med: There are 67 herb medicines - Herba Asari(細辛) is used 15 cases, Pedicellus Melo (瓜蔕) is used 11 cases, Alunite(白礬) is used 10 cases, Realgar(雄黃)is used 9 cases. 3. The way of making the external application: obstructive method is used 19 cases, attaching method is used 9 cases, blowing method is used 8 cases, plaster method is used 7 cases, pouring method is used 3 cases. 4. The treatment takes about 1day to 15days and the soften nasal polyps like a water can be expect the positive prognosis. Conclusion: The external treatment is very important to treat nasal polyps. So we need to research more on eliminating the toxicity of the herb medicine and develop the convenient way of using the external treatment.
A Case of Idiopathic Cholinergic Urticaria Associated with Acquired Hypohidrosis by Herbal Medicine Applied Gejimahwanggakban-tang(桂枝麻黃各半湯)
Kim, Kyu-Seok ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 220~227
Acquired hypohidrosis is a rare condition of unknown pathogenesis, while idiopathic cholinergic urticaria is relatively common. We report the case of a 18-year-old male with idiopathic cholinergic urticaria and acquired hypohidrosis. He presented with an intermittent pruritic eruption precipitated by mild activity, such as mild exercise or laughing, for last 4 years. He was diagnosed with cholinergic urticaria associated acquired hypohidrosis, successfully treated by herbal medicine applied Gejimahwanggakban-tang(桂枝麻黃各半湯).
Acne Treatment Cases with Hwangryeonhaedok-tang
Oh, Chung-Sun ; Kim, Mi-Sun ; Kim, Il ; Kim, Hye-Yoon ; Park, Sung-Ik ; Choi, Seung-Il ; Hong, Dae-Sung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 228~236
Objectives : Acne, one of the most common disorders in dermatology clinic, is a chronic inflammatory disease which has the symptoms of comedones, papules, pustules, cysts, nodules and scars mainly on the face. Although some of pathologic findings are suggested, but the exact causes and mechanisms are not yet known in Western Medicine. Hwangryeonhaedok-Tang(HRHDT) is an antiinflammatory, antipyretic and detoxifying herb decoction. In this report, we would like to share our experience of acne treatment with HRHDT. Methods : We had treated several patients with acne, facial flushing and uprising febrile sensation on face using oral administration and external application of HRHDT. HRHDT is basically made up with Scutellariae Radix, Coptidis Rhizoma, Phellodendri Cortex and Gardeniae Fructus. In this trial, several other herbs were added according to the individual patient's accompanying symptoms. After the decoction of herbs in amount for 10 days,
Kefir Starter 10 g was added to the herbal solution that was then fermented in an incubator at
for 72 hours, and divided into 30 doses. Results : Photographies were taken before and after the treatment. The severities of acne were evaluated with these photos according to the Korean Acne Grading System(KAGS). As results, we observed dramatic clinical improvements and the decreases of KAGS grades after the average treatment period of 8 weeks. The medication was orally administered 3 times a day and the external treatment was applied average twice a week during the whole treatment period. Conclusions : From these results, HRHDT may be considered as a good prescription for the febrile and toxic type of acne patients.
A Case of Atopic Dermatitis with Sepsis
Yun, Young-Hee ; Son, Byeong-Kook ; Yu, Seung-Min ; Choi, In-Hwa ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 22, issue 3, 2009, Pages 237~245
Objective : It is well known that patients with atopic dermatitis are prone to cutaneous infections. Especially Staphylococcus aureus has been regarded as having an influence on atopic dermatitis. We observed and treated a case of an adult atopic dermatitis patient with sepsis by cooperation of east-west medicine. We present this case because there were no former reports of atopic dermatitis with sepsis treated by cooperation of east-west medicine. Method : We used herbal medication, acupuncture, herbal wet dressing combined with antibiotics and analgesics for 19 days. Atopic dermatitis grade was determined using SCORAD index. Result : The SCORAD index was lowered 32.3 at discharge than before of which the SCORAD index was 62.5 at admission. Other systemic inflammatory response such as fever, pus was also resolved. Conclusion : From this result, we suggest that herbal therapy associated with antibiotic therapy were shown to treat atopic dermatitis with secondary infection effectively.