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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Journal Basic Information
Journal DOI :
The Korean Oriental Medical Ophthalmology and Otolaryngology and Dermatology Society
Editor in Chief :
Volume & Issues
Volume 25, Issue 4 - Nov 2012
Volume 25, Issue 3 - Aug 2012
Volume 25, Issue 2 - May 2012
Volume 25, Issue 1 - Feb 2012
Selecting the target year
Inhibitory effect of Fagopyrum esculentum on degranulation and production of cytokine in RBL-2H3 cells
Kang, Kyung-Hwa ; Lee, Seung-Yeon ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 1~12
DOI : 10.6114/jkood.2012.25.3.001
Objectives : Fagopyrum esculentum(FE) has been used for removal of inflammation of internal organs and treatment of sore and ulcer by heat toxin in Korean herbal medicines. In this study, To investigated the protective effect of FE on allergic response, we determined whether FE inhibits allergic response. Methods : The effect of FE was analyzed by ELISA, RT-PCR and Western blot in RBL-2H3 cells. We investigated cell viability,
-hexosaminidase, as a marker of degranulation, cytokne, and intracellular ROS and MAPK and NF-
signaling. Results : We found that FE suppressed
-hexosaminidase release, the production of IL-4 and TNF-
and intracellular ROS level in RBL-2H3 by the anti-DNP IgE plus DNP-HSA stimulation. FE also significantly inhibited cytokine mRNA expressions, such as IL-
, IL-2, IL-3, IL-4, IL-5, IL-6, IL-13, TNF-
and GM-CSF in RBL-2H3. In addition, PF suppressed the phospholyation of ERK1/2, JNK1/2, p38 and
signal transduction pathway. Conclusions : Our results indicate that FE protects against allergic response and exerts an anti-inflammatory effect through the inhibition of degranulation and production of cytokines and ROS via the suppression MAPK and NF-
of signal transduction. Abbrevations : FE, Fagopyrum esculentum; RBL-2H3, rat basophilic leukemia cell line; ROS, reactive oxygen species; MAPK, Mitogen-activated protein kinase;
, nuclear factor
, Tumor necrosis factor alpha; GM-CSF, Granulocyte macrophage colony-stimulating factor; ERK, extracellular-signal-regulated kinase; JNK, c-Jun NH2-terminal kinase; p38, p38 MAP kinase;
, inhibitory-kappa B alpha.
A Literature Study of Pericarpium Granati and Cortex Betulae Platyphyllae
Park, Soo-Yeon ; Na, Chang-Su ; Jeong, Won-Cheol ; Lee, Jong-Cheol ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 13~33
DOI : 10.6114/jkood.2012.25.3.013
Objective : The aim of this study is to find the therapeutic meaning of Pericarpium Granati and Cortex Betulae Platyphyllae in herbal medication. Methods : About the origin, the component, the processing the drug, the properties and tastes of drugs, the meridian tropism, the effects, the treating disease, the contraindication and the method of adminictration, I have researched 23 literatures and 10 disquisitions to mention the Pericarpium Granati and Cortex Betulae Platyphyllae. Result : 1. Pericarpium Granati is pericarp of mature fruit of The Pomegranate belongs to Punicaceae and Cortex Betulae Platyphyllae is bark of Betula platyphylla var. japonica (Miquel) Hara belongs to Betulaceae. 2. Pericarpium Granati consists of tannin 10.4~21.3%, lead 0.8%, resin 4.5%, mannitol 1.8%, sugar 2.7%, gum 3.2%, inulin 1.0%, musilage 0.6%, gallic acid 4.0%. Cortex Betulae Platyphyllae consists of betulin about 35%, various higher fatty acid about 35%, tannin about 7%. 3. The properties and taste of Pericarpium Granati is acid, astringency, warm, nontoxic and the meridian tropism is mainly stomach and large intestine meridian. The properties and taste of Cortex Betulae Platyphyllae is bitter, cold, nontoxic and the meridian tropism is mainly stomach meridian. 4. Pericarpium Granati has come into general use to treat roundworm, tapeworm, old diarrhea, anal prolapse, melena, metrorrhagia, leukorrhea, stomachache from worms, scabies etc. because it is effective on insecticiding, stopping diarrhea, controling hemorrhage and leukorrhea. Cortex Betulae Platyphyllae has come into general use to treat shigellosis, diarrhea, jaundice, cough, sputum, tonsillitis, pneumonia, nephritis, furuncle, prurigo, acne etc. because it is effective on cooling down heat, circulating humidity, removing phlegm, stopping cough, neutralizing poison. 5. Pericarpium Granati and Cortex Betulae Platyphyllae is useful method to external care. To use the herba, pulverize amount of property and then apply to the affected part. Conclusion : This study showed that Pericarpium Granati and Cortex Betulae Platyphyllae is useful herb to treat of skin disease and useful method to external care.
A Review of Experimental Study for Herbal Medicines of Anti-allergic Effects
Lee, Woo-Gun ; Hong, Eu-Gene ; Kim, Bong-Hyun ; Kim, Kyu-Seok ; Nam, Hae-Jeong ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 34~55
DOI : 10.6114/jkood.2012.25.3.034
Objective : The purpose of this study is to survey the experimental studies for Herbal Medicines of Anti-allergic Effects by reviewing oriental medicine journals. Methods : We collected 48 research papers on Oriental herbal medicines (prescriptions, herbs and aqua-acupunctures) of Anti-allergic effects in the internet site OASIS using the keyword 'Antiallergy'. Then we analyzed them according to published journals, years, and research methods, etc. Results : 48 papers in relation to Oriental herbal medicines of anti-allergic effects have been published in many kinds of journals and shows a tendency to increase every year. There are 23 cases of using herb simplexes, 21 cases of herb-combined prescription, and 4 cases of aqua-acupuncture. Conclusions : This result will provide useful information of field of Oriental herbal medicine for the development of anti-allergic related herb simplexes and herb combined prescriptions. In the future, we have to perform more studies such as clinical trial and research papers on combined medication of the oriental and the western medicines for anti-allergic effects.
Survey on Effect and Satisfaction of Korean Medicine Distillate Nasal Spray of Patient with Chronic Rhinitis
Kim, Ji-Eun ; Hong, Chul-Hee ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 56~64
DOI : 10.6114/jkood.2012.25.3.056
Objectives : This study was performed in order to investigate an immediate improvement effect of nasal obstruction after having patient with chronic rhinitis use nasal spray in nasal cavity after distilling Korean medicine, satisfaction for its fragrance and irritation and its effect continuance time. Methods : A questionnaire was performed for an immediate therapeutic effect of nasal spray 1, 2 and 3 weeks later after using spray by targeting 13 patients who used Korean medicine distillate spray for over 3 weeks among the patients who visited Sangji University Korean Medicine Hospital and whose symptoms were determined as chronic rhinitis and for whom Korean medicine distillate spray was prescribed. 3 weeks later after using spray, a questionnaire was performed for fragrance, irritation and continuance effect of Korean medicine. Immediate therapeutic effect being felt right after spraying was also surveyed and symptom scores was expressed from 10 to 0 and on the assumption that nasal obstruction symptom just before spraying was 10 points, symptom score after spraying was surveyed. In case of evaluation of satisfaction, satisfaction for fragrance and irritation of nasal spray was evaluated by scale based on full score of 5 point from 'very satisfied=5', 'satisfied=4', 'average=3', 'unsatisfactory=2' and 'very unsatisfactory=1', respectively. Effect continuance time after spraying was surveyed by dividing it into within 5 minutes, within 5-10 minutes, within 10-30 minutes and over 30 minutes. All the data was statistically analyzed by Friedman Test that is non-parametric test of Paired t-test and descriptive statistics. Results : Total surveyed patients were 13 persons including 6 males and 7 females and total average age was represented to be
years old. Score of immediate nasal obstruction improvement effect at 1st week was
points, at 2nd week
points and at 3rd week
points and when comparing 1st week, 2nd week and 3rd week statistically, p value was 0.047<0.05 and from this, it could be seen that the longer spray was used, the more was improvement effect represented with slight significance. In case of fragrance and irritation, both of its score was represented to be high as average
points and average
points, respectively. Effect continuance time below 10 minutes was represented in 8 persons who accounted for 61.5%. Conclusions: Immediate improvement effect of nasal obstruction being felt by the patients by using Korean medicine nasal spray could be confirmed and by having the patients use such spray for 3 weeks continuously, it could be realized that such effect was sustained and satisfaction for fragrance or irritation of Korean medicine nasal spray was significant. However, rather short sustained time was considered to be unsatisfactory and this shortcomings is required to be improved in the future.
A Survey of Students' Satisfaction on Participation Learning Using Role-play in Clerkship
Song, Min-Kyung ; Hong, Seung-Ug ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 65~77
DOI : 10.6114/jkood.2012.25.3.065
Objectives : The purpose of this study is to evaluate students' satisfaction on participation learning using role-play in clerkship of Oriental Ophthalmology & Otolaryngology department. Methods : In 2012, 93 sixth grade students undergoing Oriental Ophthalmology & Otolaryngology clerkship were included in this study. The students listened to a lecture on nasal disease. And three days later, Students were randomly divided into two groups, doctor or patient, and performed role-play in their role. After role- play, they completed the questionnaire, the questionnaire was composed of 16 items. Results : Mean of total satisfaction score was 4.14. Mean of interest and appropriacy score was 4.48, mean of usefulness satisfaction was 3.93. There was no significant difference in mean scores by the role groups. Students evaluated the role-play in clerkship positively. Conclusions : Students evaluated the role-play that it was interesting and useful educational tool in clerkship. It is necessary to undergo further trials and complement programs to upgrade the quality of Oriental medical clerkship.
The Judicial Precedent Analysis of Medical Litigation in the field of Pediatric Ophthalmology
Lee, Mee-Sun ; HwangBo, Min ; Seo, Hyung-Sik ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 78~87
DOI : 10.6114/jkood.2012.25.3.078
Objective : The purpose of this study is to describe the characteristics of medical malpractice related to pediatric ophthalmology and to identify the causes and potential preventability of medical litigation in Korean medicine. Methods : A study was performed by analysing 8 cases of lawsuit in the year between 1968 and 2011, which were selected among the medical dispute cases involving pediatric ophthalmology. Results : The eight closed claims occurring in the field of pediatric ophthalmology were founded in the data for medical malpractice. One claim was supreme court decision, two claims were high court decisions and five claims were district court decisions. Conclusions : While malpractice claims occurring in the field of pediatric ophthalmology were uncommon, they resulted in a high rate and amount of indemnity payments. For reduction of medical disputes, improvement of clinical trials and clinical medical cares is emphasized, and informed consent is also important.
Analysis the skin physical properties of periorbital region and cheek based on female's aging pattern by 7 years
Cho, Ga-Young ; Kim, Jee-Yeun ; Yeom, Myung-Hun ; Cho, Jun-Cheol ; Kim, Yoon-Bum ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 88~96
DOI : 10.6114/jkood.2012.25.3.088
Objectives : We investigated the skin properties on the periorbital region and cheek of Korean female according to age pattern by 7year based on Sang Go Cheun Jin Ron (上古天眞論) in So Moon (素問,) Methods : 49 Korean females, aged 21-56 years (
years) were participated in this study. We measured the skin properties of periorbital region and cheek with SkinTouch (Amorepacific, Korea). Skin moisture, sebum, elasticity, lightness, roughness, area of wrinkle, depth of wrinkle were assessed. Results : Differences were noticed depending on the site and age. The level of moisture was higher on the eyelid than crow's feet. The level of lightness and elasticity were lower on the periorbital region than cheek. Skin lightness was highest on group1(under 28y) and lowest on group5(over 49y). Skin roughness was highest on group1(under 28y) and lowest on group4(over 42y under 49y). The level of wrinkle are was lowest on group1(under 28y) and highest on group 5(over49y). The level of wrinkle depth was lowest on group1(under 28y) and highest on group 4(over 42y under 49y). Conclusion : Unique aging pattern by 7 years of female is reflected to diverse skin properties of eyes. It can be possible to apply the theory on Sang Go Cheun Jin Ron (上古天眞論) to practical use in dermatology and cosmetic.
A Clinical Study about the Effects of oriental medical therapy on obesity and different effects between groups
Lee, Soo-Jung ; Kim, Won-Il ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 97~112
DOI : 10.6114/jkood.2012.25.3.097
Objectives : The purpose of this study were to evaluate the effects of oriental medical therapy on obesity and different effects according to Body Mass Index(BMI), menopause, obesity treatment experience, age, treatment period in patients. Methods : 46 patients were treated from November 2011 to April 2012 in Oriental Obesity Center, Dong-eui Medical Center. They were measured change of body compositions by bioelectrical impedance analysis every 2~3 weeks and 27 patients out of 46 were checked body compositions every 2 weeks. 46 and 27 patients were divided into two or three groups according to BMI, menopause, obesity treatment experience, age, treatment period. We compared before and after treatment body compositions. Results : Body compositions, except edema index were significantly reduced. Abdominal Visceral Fat(AVF) was significantly reduced in Obese group. Body Weight(BW), BMI, Body Fat(BF), Body Fat Percetage(BFP), Abdominal Visceral Fat Level(AVFL), Abdominal Visceral Fat(AVF), Abdominal Subcutaneous Fat(ASF) were significantly reduced in non-menopause group(43 female patients). But in 26 female patients out of 27, there were no significantly differences between groups in menopause. There were no significantly differences between groups in obesity treatment experience. But in 27 patients, BMI and AVF were significantly reduced in non-experience group and AVFL was significantly reduced in experience group. BW, BMI, BF, BFP, VAF, ASF were significantly reduced in younger age group. But in 27 patients, BW and Muscle were significantly reduced in younger age group. BMI, BF, BFP, Edema, AFVL, Abdominal Visceral Fat Area(AVFA), AVF, ASF were significantly reduced in longer treatment period group. Conclusion : The BF, BMI, BF, BFP, Muscle, AVFL, AVFA, AVF, ASF were almost decreased significantly. It resulted that the effects of oriental medical therapy in obesity was positive. And it was meaningful study to know about different effects between groups.
The Clinical investigation studies in early stage of intractable peripheral facial paralysis using Needle-Embedding Therapy
Han, Jung-Min ; Yoon, Jung-Won ; Kang, Na-Ru ; Ko, Woo-Shin ; Yoon, Hwa-Jung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 113~128
DOI : 10.6114/jkood.2012.25.3.113
Objectives : This study was performed to investigate the effect of Needle-Embedding Therapy in early stage of intractable peripheral facial paralysis. Methods : 46 patients with severe peripheral facial paralysis were treated with oriental medicine therapy including Needle-Embedding Therapy in their early stage. We evaluated the effect of Needle-Embedding Therapy by House-Brackmann Grading system, decrease of subjective symptoms and satisfaction measurement. Results : After treatment, HB-Scale grade was significantly decreased(p-value<0.001). More than 50% of subjective symptoms were disappeared in 82.61% of patients. 80.48% of the patients was satisfied with the Needle-Embedding Therapy. Conclusion : Needle-Embedding Therapy could be effective to improve symptoms of severe peripheral facial paralysis in early stage. Further studies will be required to identify the beneficial effect of Needle-Embedding Therapy in early stage of peripheral facial paralysis.
A Clinical Study for the effect of cosmetic cream containing Samwhangsejegamibang Extracts on Atopic dermatitis patients
Joo, Hyun-A ; Bae, Hyeon-Jin ; Park, Min-Cheol ; Baek, Sang-Chul ; Hong, Seok-Hoon ; Yang, Hyun-Ju ; Cho, Hyun-Woo ; Jung, Soo-Young ; Cho, Jeong-Hee ; Hwang, Chung-Yeon ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 129~149
DOI : 10.6114/jkood.2012.25.3.129
Objective : The purpose of this study is to investigate the effect of cosmetic cream containing Samwhangsejegamibang Extracts on Atopic dermatitis patients. Methods : A total of 51 patients who visited Wonkwang Oriental Medical Center from April 8th, 2011 to October 8th, 2011 were included in this study. In this study, the patients were treated with Samwhangsejegamibang (experimental group) and placebo group. We observed scorad index, IGA, moisture content of skin, oil content of skin, wrinkled skin and hematological examination for 4 weeks. Results : 1. Comparison of changes in Scorad Index, depending on the perspective, the experimental group showed a statistically significant decline than the placebo group. 2. Comparison of change in IGA, depending on the perspective, the experimental group showed a statistically significant decline than the placebo group. 3. Comparison of change in moisture content, oil content of skin and wrinkled skin, both the experimental group and the placebo group showed level elevation but there was no statistically significant change. 4. Comparison of change in IgE and Eosinophil, both the experimental group and the placebo group showed no statistical significance. Conclusions : Considering the above experiments, it is suggested that cosmetic cream containing Samwhangsejegamibang extracts have a positive effect on atopic dermatitis patients.
The Efficacy of Korean Herbal Cosmetics for Facial Skin Elasticity
Kim, Min-Hee ; Yun, Young-Hee ; Cho, Ga-Young ; Choi, In-Hwa ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 150~159
DOI : 10.6114/jkood.2012.25.3.150
Objective : The purpose of this study was to evaluate the effect of korean herbal cosmetics for facial skin elasticity. Methods : We recruited patients and divided them to cosmetics group and control group randomly. We provided korean herbal cosmetics to cosmetics group and subjects in cosmetics group applied the provided cosmetics for 4 weeks. Control group waited and applied cosmetics that had previously used for 4 weeks. We assessed all subjects in 0 week, 2 weeks and 4 weeks. Primary assessment instrument was moire topography photo scale. Second assessment instrument was skin moisture, oiliness and elasticity which assessed with skintouch system v1.0, detox/regeneration questionnaire score and self-evaluating facial wrinkle/looseness score. Result : Moire topography photo scale improved in cosmetics group than control group significantly. Skin moisture and elasticity assessed with skintouch system improved in cosmetics group than control group significantly while skin oiliness assessed with skintouch system have not improved significantly. Detox/regeneration questionnaire score and self-evaluating facial wrinkle/looseness score improved in cosmetics group than control group significantly. Conclusion : Korean herbal cosmetics application might be effective method for facial skin elasticity.
A Case Report of Post-herpetic Neuralgia Improved by Oriental Medicine with Depletion and Cupping Therapy
Kim, Tae-Yeon ; Kim, Hyun-Jung ; Kim, Chang-Hwan ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 160~167
DOI : 10.6114/jkood.2012.25.3.160
Objective : This study reports the effect of oriental medicine with depletion and cupping therapy on post-herpetic neuralgia(PHN) 1 case. Methods : We experienced one case of PHN treated by oriental medical treatment with depletion and cupping therapy. To evaluate the effectiveness of this treatment, we used the Visual Analogue Scale(VAS). Result : After the treatment the grade of VAS was decreased and clinical symptoms were improved. Conclusion : Oriental medicine with depletion and cupping therapy can be available for relieving symptoms related with PHN.
A Case of Chronic Suppurative Otitis Media treated with Oriental medicine
Choi, Eun-Ji ; Yun, Young-Hee ; Choi, In-Hwa ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 168~174
DOI : 10.6114/jkood.2012.25.3.168
Objective : The purpose of this study is to report the effect of Oriental medicine on Chronic suppurative otitis media. Methods : We used herbal medication, acupuncture and cupping therapy were for treatment. To evaluate the results of the treatment, we observed the patient's condition and otoscopic findings. Results : The patient's objective and subjective symptoms showed noticeable improvement after treatment. Conclusions : We suggest that chronic suppurative otitis media can be treated by Oriental medicine effectively.
A Clinical Report about Eczema Worsened by Drug Eruption after taking Korean Medicine
Kang, Na-Ru ; Han, Jung-Min ; Ko, Woo-Shin ; Yoon, Hwa-Jung ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 25, issue 3, 2012, Pages 175~183
DOI : 10.6114/jkood.2012.25.3.175
Objectives : The purpose of this report is to know the effect of Younkyopaedok-san(連翹敗毒散), Sammulhwanggum-tang(三物黃芩湯) on eczema worsened by drug eruption and Gungguigyoae-tang(芎歸膠艾湯) on chronic eczema. Methods : We experienced one case of eczema treated with Younkyopaedok-san, Sammulhwanggum-tang and Gungguigyoae-tang. We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and clinical symptoms were gradually disappeared. Conclusion : Younkyopaedok-san, Sammulhwanggum-tang and Gungguigyoae-tang had improved the signs and symptoms of eczema. 1. Younkyopaedok-san and Sammulhwanggum-tang were effective on the treatment of inflammatory eczema. 2. Gungguigyoae-tang was effective on the treatment of chronic eczema.