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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Journal Basic Information
Journal DOI :
The Korean Oriental Medical Ophthalmology and Otolaryngology and Dermatology Society
Editor in Chief :
Volume & Issues
Volume 26, Issue 4 - Nov 2013
Volume 26, Issue 3 - Aug 2013
Volume 26, Issue 2 - May 2013
Volume 26, Issue 1 - Feb 2013
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A Clinical Study for Effect of Herbal Cosmetics Containing Cortex Betulae Platyphyllae Extract Complex on Acne
Park, Soo-Yeon ; Na, Chang-Soo ; Jeong, Won-Cheol ; Lee, Jong-Cheol ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 1~19
DOI : 10.6114/jkood.2013.26.3.001
Objective : The primary purpose of present study is to evaluate the effect of herbal cosmetics containing Cortex Betulae Platyphyllae extract complex on acne. The second is to comparatively evaluate safety of this cosmetics. Methods : We opened collecting of applicant that men and women(the 18~35-year-old) with acne on face. We selected subjects who came up to entire inclusion criteria and were not included in the exclusion criteria. We checked changes of Acne Global score, skin sebum, moisture, pores counts, Skindex-29 for 8 weeks. Results : 1. Comparison of changes in Global score, it declined in both experimental group and control group. But Experimental group showed a statistically significant decline than control group. 2. Comparison of changes in sebum and moisture, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. 3. Comparison of changes in erythema normal area, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. 4. Comparison of changes in pore counts, it increased statistically significantly in both experimental group and control group. 5. Comparison of changes in Skindex-29, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. Conclusion : Considering the above experiments, it is suggested that herbal cosmetics containing Cortex Betulae Platyphyllae extract complex have a positive effect on acne.
Study on a Usage of Smoking Preparations, Fumigant and Buccal Preparations in 『Dongeuibogam』
Kwon, Jae-Won ; Yang, Yoon-Hong ; Lee, Boo-Kyun ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 20~35
DOI : 10.6114/jkood.2013.26.3.020
Objectives : The purpose of this study is to provide grounds for the development of preparation of Korean medicine through investigating the usage of smoking preparation, fumigant and buccal preparations in "Dongeuibogam". Methods : We have researched the usage of related preparations as following procedure : 1. Choosing a related words such as combustion(燒, 燎, 燃) smoking(烟), fumigation(熏, 熏烟, 熏洗), inhalation(聞, 嗅, 齅), holding in mouth(含, 噙). 2. Searching sentences : We have searched sentences containing the related words in "Dongeuibogam", analyzed the selected sentences and made tables of the usage including indication, formula, material. Conclusions : 1. Smoking preparations and Fumigant can be classified into two different groups : 1) internal usage for the treatment of internal diseases such as dizziness, congestion, stroke, cough. 2) external usage for the treatment of wounds, sores, genital diseases, anal disease and for the prevention of diseases. 2. Buccal preparation is mainly used for the treatment of mouth, tongue, throat and lung diseases. 3. These preparations have been used not only for external diseases but internal diseases. 4. Each preparation has chief herbs for its peculiar properties of treatment.
Effect of DOGO phreatic water containing sulphur on Atopic Dermatitis in NC/Nga mouse
Jang, Moon-Hee ; Go, Ga-Yeon ; Ahn, Yo-Chan ; Ahn, Taek-Won ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 36~53
DOI : 10.6114/jkood.2013.26.3.036
Objectives : The purpose of this study is to investigate the effects of DOGO phreatic water containing sulphur on Atopic Dermatitis in NC/Nga mouse. Methods : We made DOGO phreatic water removed sulphur using Twin Alternating Sulfate Eater. After making atopic dermatitis caused by sensitizing NC/Nga mouse to DNCB(dinitrochlorobenzene), we made mouse swim in tanks each filled with distilled water, tap water, DOGO phreatic water(contain sulphur), DOGO phreatic water(remove sulphur) for 30minutes everyday. 3weeks later, we analyzed skin clinical score, total IgE levels(by ELISA), WBC differential counting(Neutrophils, Monocytes), absolute cell number of
, CCR3 mRNA expressions(by Real-time PCR), IL-4, IFN-
production levels(by ELISA), histologic test(by H&E staining, toluidine blue staining). Results : The results of making NC/Nga mouse induced atopic dermatitis swim in tanks filled with DOGO phreatic water(contain sulphur) are as follows. 1. Skin clinical scores were decreased significantly in comparison to control group. 2. Total IgG levels were decreased significantly in comparison to control group. 3. WBC differential counting(Neutrophils, Monocytes) were decreased significantly in c.mparison to control group. 4. Absolute cell number of
were decreased significantly in comparison to control group. 5. CCR3 mRNA expressions were decreased significantly in comparison to control group. 6. IL-4, IFN-
production levels were decreased significantly in comparison to control group. 7. The epithelial tissue thickness, leucocytes infiltration, erythema, edema, excoriation, scaling, mast cells infiltrations in dorsal skin were decreased in comparison to control group. Conclusions : These results indicate that DOGO phreatic water(contain sulphur) can be used for helping treat atopic dermatitis.
Anti-inflammatory Effect of Stevia Rebaudiana as a Results of NF-κB and MAPK Inhibition
Kim, Seon-Young ; Jo, Mi-Jeong ; Hwangbo, Min ; Back, Young-Doo ; Jeong, Tae-Young ; Cho, Il-Je ; Jee, Seon-Young ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 54~64
DOI : 10.6114/jkood.2013.26.3.054
Objectives : Stevia rebaudiana is a well-known herbal sweetener in the Korea, Japan and China, and its medical uses were originated from countries in South America. Although it has been shown the various medical effects of S. rebaudiana including contraception and treatment of human diseases such as hyperglycemia, it has almost not been studied about the efficacy of S. rebaudiana methanolic extract (SRE) on the acute inflammation and its action mechanism. Methods : To investigate the anti-inflammatory effects of SRE, we treated SRE and examined the level of inflammatory mediators in LPS-stimulated Raw264.7 cells. Results : Treatment of macrophage with LPS markedly induced the production of NO,
and pro-inflammatory cytokines. Pretreatment of SRE blocked the induction of inflammatory mediators and the expression of iNOS protein. More importantly, LPS-induced phosphorylation of
was suppressed by the treatment of SRE, suggesting SRE inhibition of NF-
activation. Furthermore, SRE blocked LPS-induced phosphorylation of MAPKs. Conclusions : SRE inhibited the induction of NO, PGE2 and pro-inflammatory cytokines in Raw264.7 cells. SRE's effect may be mediated with its inhibition of NF-
activation and MAPK phosphorylation, which suggests its uses as an anti-inflammatory agents.
Retrospective Study about the Effectiveness of a long-term Korean Medicine Treatment on 511 Atopic Dermatitis Patients
Han, Su-Ryun ; Park, Gun ; Han, Myeong-Hwa ; Seo, San ; Cho, Jae-Gon ; Ko, Young-Hyup ; Jung, Chang-Hwan ; Lee, Jung-Hwan ; Jang, Jin-Young ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 65~76
DOI : 10.6114/jkood.2013.26.3.065
Objective : The purpose of this study is to report the effectiveness of a long-term Korean Medicine Treatment on 511 atopic dermatitis patients. Methods : Total 511 atopic dermatitis patients, who has visited oriental medical clinics from 2011.1.9 to 2012.1.31 and continued treatment 3 month to 9 month were analyzed by Objective SCORAD Index(OSI). Subanalysis of OSI were done according to gender, age, treatment period, and intensity. Results : 1. Male and female percent was 42.5:57.5. Age percent was 0 to 11:12 to 18:above 19=30:16.6:53 and 41.9% was steroid users. 2. OSI Improvement rate was significantly higher in women than men after 3 month of treatment, but not significant after 6, 9 month of treatment. 3. There was no improvement difference of OSI among the age. 4. OSI was significantly lower after 3, 6, 9 month of treatment. Average post-treatment score was lowest in 9 month treatment group. 5. 86.7% of total patients reported decrease in OSI score at the final visit. 6. 85.9% was severe, 13.5% was moderate, and 0.6% was mild by OSI intensity assessment at initial visit. The percent changed at final visit to 37% severe, 54.2% moderate, and 8.8% mild. 7. Patient diagnosed as OSI intensity severe at first visit, their average treatment period was 6.58 months and final improvement rate was 36.27%. Conclusion : A significant percent of Atopic dermatitis patients who were treated with Korean Medicine Treatment reported decrease in OSI. There was significant decrease in OSI before and after 3, 6, 9 month treatment. The difference increased with the treatment period.
A Case Report of Ptosis Patient Diagnosed as Idiopathic Oculomotor Nerve Palsy
Kim, Tae-Yeon ; Kim, Hyun-Jung ; Lee, Chang-Won ; Kim, Chang-Hwan ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 77~86
DOI : 10.6114/jkood.2013.26.3.077
Objective : This study reports the effect of korean medicine on ptosis patient 1 case diagnosed as idiopathic oculomoter nerve palsy. Methods : We experienced one case of ptosis diagnosed as idiopathic oculomoter nerve palsy treated with herbal medicine and acupuncture. Ptosis and associated symptoms had been estimated with difference of both eye's interpalpebral fissure and VAS(Visual Analogue Scale). Result : After the treatment, symptoms were decreased and almost disappeared. In this case, difference of both eye's interpalpebral fissure decreased from 6mm to 1mm in a month. Conclusion : This study suggests that korean medicine is effective on ptosis diagnosed as idiopathic oculomoter nerve palsy.
A Case Report of Bogigeopung-san Applied on Trigeminal Neuralgia
Choi, Ju-Ho ; Jeong, Ju-Ho ; Lee, Jong-Cheol ; Rhee, Doo-Hee ; Choi, Jeong-Hwa ; Park, Soo-Yoen ; Kim, Jong-Han ; Jeong, Min-Yeong ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 87~94
DOI : 10.6114/jkood.2013.26.3.087
Objectives : This is a clinical report on a 63-year-old female patient with Trigeminal Neuralgia (TN) treated by oriental medicine treatments. Methods : The patient was treated by acupuncture, moxibustion and herb medication. The improvement of the patient was judged by Visual Analog Scale(VAS). Results : The pain had been gradually reduced and VAS became 2 after the treatment for 25 days. Conclusions : Oriental medicine treatment including Bogigeopung-san was very effective to improve the TN patient's symptoms. It is necessary to have more observations and cases on the patients with TN.
A Case of Acute Multiple Nummular Eczema with Exudation
Jang, In-Wook ; Han, Jung-Min ; Yoon, Hwa-Jung ; Ko, Woo-Shin ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 3, 2013, Pages 95~104
DOI : 10.6114/jkood.2013.26.3.095
Objective : The purpose of this report is to know the effect of oriental medical treatments on acute multiple nummular eczema with exudation. Methods : We treated a 41-years-old woman patient with nummular eczema on right shin and left upper arm with Korean medicine. After Korean medical treatment for 31 days, we measured the decrease of exudation and recovery of skin damages. We recorded pictures of changes on symptoms. Results & Conclusion : The symptoms of nummular eczema were significantly improved except scars. Exudation was disappeared and skin damages were almost recovered. Pruritus was decreased by 70%. Thus Korean medical treatments are effective on acute multiple nummular eczema with exudation.