Go to the main menu
Skip to content
Go to bottom
REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Journal Basic Information
Journal DOI :
The Korean Oriental Medical Ophthalmology and Otolaryngology and Dermatology Society
Editor in Chief :
Volume & Issues
Volume 26, Issue 4 - Nov 2013
Volume 26, Issue 3 - Aug 2013
Volume 26, Issue 2 - May 2013
Volume 26, Issue 1 - Feb 2013
Selecting the target year
The Effects of Syzygium aromaticum extract Spread on the Allergic Contact Dermatitis induced by DNCB
Lee, Kyung-Yeob ; Kang, Da-Hae ; Kim, Hee-Taek ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 1~14
DOI : 10.6114/jkood.2013.26.4.001
Objectives : The purpose of this study is to investigate effects of Syzygium aromaticum (SAE) spread on the allergic contact dermatitis caused by 2,4-dinitro-chlorobezene (DNCB). Methods : Forty-two mice were divided into six groups ; normal, negative control (DNCB-treated), positive control (DNCB + 1% pimecrolimus), experimental group I, II and III. control and experimental groups were induced allergic contact dermatitis by DNCB. Experimental group I(DNCB + 0.2% SAE), II(DNCB + 1% SAE) and III(DNCB + 5% SAE) were spread SAE and positive control was spread the 1% pimecrolimus. In this study, effect of SAE on clinical aspects on the skin, histopathological change, the blood level of IgE, cytokines, histamine were investigated. In addition, effect of SAE on spleen
T cell subset was investigated. Results : 1. In experimental group I, II and III, erythemas and edema were more reduced than negative control. 2. In experimental group I, II and III inflammatory edema and the numbers of infiltrated inflammatory cells were more reduced than negative control. 3. In experimental group I, II and III, clinical skin score was more reduced than negative control. 4. In experimental group II and III, the thickness of skin was statistically significant reduced than negative control. 5. In experimental group II and III, histamine release was statistically significant reduced than negative control in dose-dependantly. 6. In experimental group II and III, cytokines (IL-1
, IL-4, IL-6, IL-10) were statistically significant reduced than negative control in dose-dependantly. 7. In experimental group I, II and III, the level of total IgE was statistically significant reduced than negative control in dose-dependantly. 8. In experimental group III,
T cells were statistically significant decreased similar to the positive control. Conclusions : According to above experiments, Syzygium aromaticum(SAE) was effective on allergic contact dermatitis.
Acute Oral Toxicity of Alismatis Rhizoma in SD Rats
Seok, Ji-Hyun ; Roh, Hang-Sik ; Jeong, Ja-Young ; Ha, Hun-Yong ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 15~25
DOI : 10.6114/jkood.2013.26.4.015
Objectives : This study was carried out to evaluate the acute oral toxicity of Alismatis Rhizoma in Sprague-Dawley(SD) rats. Methods : male and female rats were administered orally with Alismatis Rhizoma water extract of 1,000 mg/kg (low dosage group), 2,000 mg/kg(middle dosage group) and 4,000 mg/kg(high dosage group). We daily observed number of deaths, clinical signs and gross findings for 7 days. After 7 days, we measured body and organs weight. Also we analyzed hematological changes. Results : No dead SD rats and no clinical signs were found during the experiment period. Also other specific changes were not found between control and treated groups in hematology and serum biochemistry. In addition no significant changes of gross body and individual organs weight. Conclusions : These results suggest that water soluble extract of Alismatis Rhizoma has not acute oral toxicity and oral
value was over 4,000 mg/kg in SD rats.
Reviewing Research on Korean medical treatment of Psoriasis
Hong, Seok-Hoon ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 26~42
DOI : 10.6114/jkood.2013.26.4.026
Background : The purpose of this study is to analyze research trends on the korean medical treatment and develop the way of psoriasis cure. Object & Method : This study is based on analysis of recent paper about korean medical treatment of psoriasis using WKUCL(Wonkwang University Central Library) and NDSL(National Discovery for Science Leader). I searched papers using the keyword "Psoriasis". Inclusion criteria was last 13 years. Result : A total 19 studies were found. They turned out to be effective treatment methods of acupuncture, moxibustion, internal medicines, external applications, and evaluation tool of PASI(psoriasis area and severity index). Conclusion : According to the results, korean medical treatments have good effects on psoriasis. If we accumulate the more clinical reports, it will be helpful to map out a systematic treatment of korean medicine on psoriasis.
Preliminary Standard Procedure for Face Lift and Correction of Nasolabial Fold using Thread-Embedding (Maeseon) of Korean Medicine
LeeL, Jae-Chul ; Park, Sun-Hee ; Yoon, Jeong-Ho ; Kim, Jung-Won ; Lim, Chang-Gyu ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 43~50
DOI : 10.6114/jkood.2013.26.4.043
Objectives : This study aims to suggest preliminary standard procedure for face lift and correction of nasolabial folds using thread-embedding (Maeseon) of Korean medicine(KM). Methods : Three KM practitioners of facial correction and rejuvenation who have over hundred case of practice participated in establishment of standard procedure. Standard procedure contains preprocessing, main procedure for correction, and solution of side effects. Results : Standard procedure is comprised of twelve processes with preprocessing and postprocessing. Preprocessing has position, disinfection, and anesthesia. Main process consists of overall structure correction, face lifting, nasolabial folds correction, and mesh making on cheek. Postprocess covers disinfection, edema prevention. Conclusions : To our knowledge, this is the first work to suggest standard procedure of facial rejuvenation using Maeseon. It would contribute to standardized practice in clinical fields and future study of revealing Maeseon`s effectiveness.
Ryodoraku pattern classifications of tinnitus patients using cluster analysis
Kim, Bong-Hyun ; Hong, Eu-Gene ; Shin, Jun-Hyuk ; Nam, Hae-Jeong ; Kim, Kyu-Seok ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 51~59
DOI : 10.6114/jkood.2013.26.4.051
Objective : The aim of this study is to classify the patterns of Ryodoraku using cluster analysis on tinnitus patients. Method : 261 patients with tinnitus and 159 patients with other disease were analyzed. We used cluster analysis with SPSS 20.0 to classify the pattern of Ryodoraku. We searched the cluster characteristics and tried to interpret the specific patterns from previous studies. Result : We divided tinnitus patients to four groups and control patients to five groups. There were some shared patterns between tinnitus group and control group. One group on tinnitus patients showed lower age than other groups. Time, sex, total average did not show any differences among groups. Conclusion : Cluster analysis on tinnitus patients showed the possibility of presenting the specific Ryodoraku patterns. But because of weak Ryodoraku studies, clinical usefulness is unknown. Further study is needed.
The Effect of Gamisungmagalguntang(加味升麻葛根湯) on Chronic Urticaria Identified as "Wind Heat" Pattern
Hong, Eu-Gene ; Kim, Bong-Hyun ; Shin, Jun-Hyuk ; Nam, Hae-Jeong ; Kim, Kyu-Seok ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 60~69
DOI : 10.6114/jkood.2013.26.4.060
Objective : This case series study was designed to assess the effect of Gamisungmagalguntang for chronic urticaria identified as "Wind-Heat" pattern by retrospective methods. Methods : We treated 19 patients for chronic urticaria with Gamisungmagalguntang(加味升麻葛根湯), who visited to care chronic urticaria at the department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine at Kyunghee University Korean Medical Center from 1st January 2013 to 31st August 2013. We analyzed information and body conditions of 19 patients. And by using Urticaria Activicy Score(UAS), frequency and number of wheals, itch severity and total score on a 4-point(0-3) scale were assessed in 19 patients. The change of each criterion and total scores between baseline and follow up were analyzed using paired t-test and Wilcoxon test(p<0.05). Results : 1. UAS improvement was statistically significant(p<0.001). Effects of symptom improvement were excellent(31.58%) that means symptom remission and good(42.10%) that means symptom improved over 50%. 2. Heat sensitivity as suspected provocation factor could be a marker for the Wind-Heat pattern urticaria. 3. Among the Wind-Heat pattern urticaria patients, normal digestion(52.63%) and no thirst(78.95%) were higher than abnormal conditions. Whereas about sweat item, abnormal conditions(57.89%) were higher than normal. That means abnormal sweat conditions could be a marker for a defense qi(衛氣) dysfunction of the Wind-Heat pattern urticaria. Conclusions : Our findings suggest that Gamisungmagalguntang could be effective on the Wind-Heat pattern urticaria.
Anti-Inflammatory Effects of Haliotidis Concha
Moon, Soo-Young ; Kim, Young-Woo ; Kim, Sang-Chan ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 70~80
DOI : 10.6114/jkood.2013.26.4.070
Objectives : Haliotidis Concha has been used to treat various human diseases such as liver dysfunction and inflammatory disorder. Although it has been shown the effects of Haliotidis Concha on the various diseases, it has almost not been studied about the anti-inflammatory effects of the Haliotidis Concha and its mechanisms. Methods : This research investigated the effects of the Haliotidis Concha ethanol extract (HCE) on the production of nitric oxide (NO) and prostaglandin
) as well as tumor necrosis factor-alpha (TNF-
). The protein expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were assayed by immunoblot analyses, and the productions of NO,
were assessed by ELISA. Results : Haliotidis Concha decreased the production of NO and
, and inhibited the expression iNOS and COX-2 proteins in a concentration-dependent manner in LPS-treated Raw 264.7 cells. HCE suppressed the ability of LPS to activate the signaling pathways of nuclear factor kappa B (NF-
) as indicated by HCE inhibited nuclear NF-
level and I-
phosphorylation. Also, HCE inhibited mitogen-activated protein kinases (MAPKs). Conclusions : HCE repressed the production of LPS-inducible NO,
, which may be mediated by inhibition of NF-
translocation. This study suggest the use for the treatment of acute inflammatory disorders.
A Case of Pustulosis Palmaris et Plantaris
Lee, Kyou-Young ; Hong, Chul-Hee ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 81~90
DOI : 10.6114/jkood.2013.26.4.081
Objectives : The aim of this study is to assess change of the skin and quality of life of the Pustulosis Palmaris et Plantari patient by Traditional Korean Medicine. Methods : We used Bihaesamsp-tanggagambang and herbal medication for external use. The progress is evaluated by Dermatology Life Quality Index (DLQI), and the patient gave marks about the subjective symptoms from 0 to 4. Results : Through the treatment, Dermatology Life Quality Index (DLQI) changed from 29 to 22, and subjective symptoms of both itching and burning sensation changed from 4 to 1. Conclusions : Traditional Korean Medicine seems to be effective for the Pustulosis Palmaris et Plantari treatment. More clinical cases and studies are needed to develop an organized therapeutic measures.
Two cases of a Dyshidrotic Eczema improved with Fulinggancao-Tang
Jo, So-Hyun ; Jo, Eun-Hee ; Park, Min-Cheol ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 91~100
DOI : 10.6114/jkood.2013.26.4.091
Background and Objective : Dyshidrotic Eczema is characterized by a pruritic vesicular eruption on the fingers, palms, and soles. It is an acute, chronic, or recurrent dermatosis. The causes of dyshidrosis are unknown. There are many treatments available for dyshidrosis including topical steroids but long term treatment of streoids may have side effects. The purpose of this study is to find out the effect of Fulinggancao-Tang on Dyshidrotic Eczema. Methods : We have diagnosed the patients through the Shanghanlun six meridian patterns diagnostic system and we treated the patients with Fulinggancao-Tang. The severity of Dyshidrotic Eczema was evaluated by visual analogue scale(VAS). Results : After the treatment itching and vesicles of hands and foots were all disappeared in both patients. Conclusions : Fulinggancao-Tang have improved the signs and symptoms of Dyshidrotic Eczema case. It is considered that Fulinggancao-Tang is considerably effective on the treatment of skin disease that especially vulnerable to water.
Four cases of Seborrheic Dermatitis treated by Fermented Yungyo Keumeunhwa Extract External treatment Liquid
Kim, Ki-Bae ; Kim, Tae-Wook ; Choi, Sung-Hee ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 101~110
DOI : 10.6114/jkood.2013.26.4.101
Objectives : The purpose of this study is to report the effect of Fermented Yungyo Keumeunhwa Extract External treatment Liquid on Seborrheic Dermatitis. Methods : Four Seborrheic Dermatitis patients on the face of each Diluted Yungyo Keumeunhwa Extract External treatment Liquid patch was 10 minutes. Results : The Fermented Yungyo Keumeunhwa Extract External treatment Liquid was effective on alleviation of symptoms like flare, scale, uredo and pricking on Seborrheic Dermatitis. Conclusions : The result indicate that Fermented Yungyo Keumeunhwa Extract External treatment Liquid has an available effect on Seborrheic Dermatitis, and authors consider that the additional clinical studies are needed to verify the effectiveness of monotherapy.
A Case Report of patient underwent Debridement caused by Cellulitis improved with Gamisunbangwhalmyung-Eum
Choi, Yong-Ju ; Bae, Hueon-Jin ; Hong, Seok-Hoon ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 111~118
DOI : 10.6114/jkood.2013.26.4.111
Objective : The purpose of this report is to know the effect of Gamisunbangwhalmyung-Eum(加味仙方活命飮) on pain and burning sensation that last for months after Debridement caused by Cellulitis. Methods : We experienced one case of patient underwent Debridement caused by Cellulitis treated with Gamisunbangwhalmyung-Eum. To evaluate the effectiveness of this treatment, we used the Visual Analogue Scale(VAS). Results : After the treatment, the grade of VAS was decreased and clinical symptoms were improved. Conclusion : Gamisunbangwhalmyung-Eum can be used on the treatment of patient underwent Debridement caused by Cellulitis.
A Case of Syringoma Improved Treated with Traditional Korean medicine
Choi, Eun-Ji ; Yun, Young-Hee ; Lee, Kyu-Jin ; Choi, In-Hwa ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 119~126
DOI : 10.6114/jkood.2013.26.4.119
Objective : The purpose of this study is to report the effect of Traditional Korean medical treatments on syringoma. Methods : We used herbal medication, acupuncture and cupping therapy for treatment. To evaluate the results of the treatment, we observed the patient`s photoscopic findings. Results : The patient`s objective symptoms showed noticeable improvement after treatment for 24days. We also found to be in good condition 21days after the treatment. Conclusions : Korean medical treatment was effective to improve the syringoma symptoms. It is necessary to have more cases and long term observation.
Case Study of Treating Acne Scars Using Reconstruction of Skin Scars and Auto Microneedle Therapy System
Heo, Jeong-Eun ; Yun, Jeong-Min ; Shin, Sang-Ho ;
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology, volume 26, issue 4, 2013, Pages 127~134
DOI : 10.6114/jkood.2013.26.4.127
Objective : Acne is very common disease, it can leave permanent scars. However, there are few reports about it in oriental medicine academia. This study performed to evaluate the effect of reconstruction of skin scars and auto microneedle therapy system on acne scars. Methods : Six patients were treated by using reconstruction of skin scars and auto microneedle therapy system. We compared the degree of treatment of acne scars on pre and post case photos and Qualitative Global Acne Scarring Grading System(QGASC). Satisfaction degree were asked from the patients. Results & Conclusion : After comparing case photos and QGASC, observing patients satisfaction, it can be considered that reconstruction of skin scars and auto microneedle therapy system to be valid acne scars treatment.