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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Korean Journal of Medicinal Crop Science
Journal Basic Information
Journal DOI :
The Korean Society of Medicinal Crop Science
Editor in Chief :
Volume & Issues
Volume 12, Issue 6 - Dec 2004
Volume 12, Issue 5 - Nov 2004
Volume 12, Issue 4 - Sep 2004
Volume 12, Issue 3 - Jun 2004
Volume 12, Issue 2 - May 2004
Volume 12, Issue 1 - Mar 2004
Selecting the target year
Inhibitory Activity of Plant Extracts against Prolyl Endopeptidase
Kim, Geum-Soog ; Lee, Seung-Eun ; Lee, Hee-Ju ; Kim, Yi-Min ; Jeon, So-Young ; Park, Chun-Geon ; Seong, Nak-Sul ; Song, Kyung-Sik ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 1~9
Prolyl endopeptidase (PEP) is proline-specific serine protease, cleaving peptide bonds on the biologically active neuropeptides such as substance P, vassopressin, and thyrotropin-releasing hormone and is, therefore, suggested to play important roles in learning and memory process. In this work, the inhibitory effect of plant extracts on PEP was investigated. Out of 200 plant extracts, Prunus mume, Pyrola. japonica, Hypericum ascyron, Astilbe chinensis var. typica, and Elaeagnus umbellata inhibited more than 90% of PEP activity at the concentration of 5 ppm.
Comparison of Growth Characteristics and Compounds of Ginseng Cultivated by Paddy and Upland Cultivation
Lee, Sung-Woo ; Kang, Seung-Won ; Kim, Do-Yong ; Seong, Nak-Sul ; Park, Hee-Woon ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 10~16
This study was carried out to investigate the difference of growth characteristics and the content of root chemical components in four years old ginseng by paddy and upland cultivation at farmers' field in Korea. Proportions of silt, clay, liquid phase and porosity were higher in paddy soil than upland soil. The range of liquid phase was
in paddy and
in upland during growth period. EC and the other contents of OM,
, and Mg in paddy soil were higher than those of upland soil, while the contents of
and Ca were less than those of upland soil. The levels of chemical components of tested soil exceeded recommended range in EC,
and Ca of paddy soil, and in
and Ca of upland soil. Stem length, fresh root weight and total dry weight per plant in paddy were greater than those of upland. Root weight in paddy-ginseng showed a great increase on September, while it was not increased in upland because of early defoliation. Net assimilation rate and crop growth rate by paddy and upland cultivation showed distinct differences on May and September, and those of paddy-ginseng were higher than those of upland-ginseng. Yield and ratio of red-colored root showed no significant difference by paddy and upland cultivation, while significant differences were observed in diameter and length of primary root, contents of crude saponin and 50% ethanol extracts of primary root, and water content of root. Hardness of primary root showed no significant difference by paddy and upland cultivation until August, but it showed distinct difference on September, at which the hardness in upland cultivation was drastically decreased.
Agronomic Characteristics and Path-coefficients of Safflower (Carthamus tinctorius L.) Collections
Park, Gyu-Hwan ; Jung, Do-Chul ; Kim, Jae-Cheol ; Jeon, Chi-Hyeong ; Kim, Kyung-Min ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 17~23
This study was carried out to obtain the basic information on mating parents and selection for high yielding safflower breeding. Thirty nine world safflower lines, which had collected from 13 countries of origjn, were evaluated for major agronomic characters, correlation and path-coefficients. The results obtained were summarized as follows. Days to flowers ranged from 83 days to 100 days. Days to flower of most foreign lines were later than that of domestic lines. Plant height ranged from 75 cm to 162 cm. The plant height and stem diameter of most foreign lines were higher than those of domestic lines. The leaf number and size of domestic lines were much more than those of foreign lines. The total branch numbers of foreign lines were more than domestic lines. Particularly, the number of third branch ranged from 0 to 25 and there were none in domestic lines. The number of corolla of foreign lines was much more than that of domestic lines. The yield of foreign lines collected from Central Asia and United States of America were more than any others. Significantly positive correlations were observed between yield and days to flower, stem diameter, the number of branch and the number of corolla. In the analysis of path-coefficient, the highest direct effects on yield was the number of corolla followed by the number of total branch, whereas those of the number of second branch and stem diameter were negative.
Enhancement of Immune Activities of Ganoderma lucidum Mycelium Cultured with Garlic Enriched Medium
Mun, Hyoung-Chul ; Lee, Hyun-Soo ; Park, Jin-Hong ; Kim, Dae-Ho ; Lee, Shin-Young ; Seong, Nak-Sul ; Bang, Jin-Ki ; Jung, Hae-Gon ; Lee, Hyeon-Yong ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 24~30
The immune activities of Ganoderma lucidum Mycelium added garlic extracts (GAM), Ganoderma lucidum Mycelium (GM), garlic extracts (GS) and standard
were compared. GAM enhanced the growth of human immune T cell up to
times, compared to control group. GAM showed relatively lower cytotoxicity in using normal human lung cell, while GAM showed the most potent inhibitory effect on the human lung carcinoma, compared to GM and GS. The selectivity of GAM was also higher than that of GM and GS. GAM increased the secretion of cytokines, IL-6 and TNF- from human B cell as well as the growth of human immune cells. It can imply that GAM has higher immune activity than GM or GS.
Intraspecific Genetic Relation of Wasabia japonica Matsum. Based on RAPD Analysis
Heo, Su-Jeong ; Kwon, Soon-Bae ; Byeon, Hak-Soo ; Seo, Jeong-Sik ; Yoo, Ki-Oug ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 31~35
The genetic variation and intraspecific relationships between 10 individuals of seven cultivars and one Ulleungdo native of Wasabia japonica were investigated using RAPD (Randomly Amplified Polymorphic DNA) analysis. The 21 primers out of 50 random primers were amplified for all tested plants. The 68 (47.2%) among 144 bands derived from 21 primers showed polymorphism, and 3.2 bands per primer were observed. Number of bands per primer was ranged from 2 to 13, and average numbers were 6.8. The phenograms for 11 analyzed individuals by RAPD markers were not matched well with those of the result by morphological characters since they were clustered monophyletic at the similarity coefficient value ranged from 0.81 to 0.96. The Ulleungdo native individual was clustered sister to Daruma, Simanesairal, Sawa, and Hujidaruma cultivars. The RAPD markers were not useful to evaluate the intraspecific variations in Wasabia japonica cultivars, therefore need to more specific molecular phylogenetic characters such as AFLP technology and gene sequence of nuclear and chloroplast DNA.
Enhanced Immune Activity and Cytotoxicity of Artemisia capillaris Thunb. Extracts against Human Cell Lines
Lee, Mi-Kyoung ; Choi, Geun-Pyo ; Ryu, Lee-Ha ; Lee, Gang-Yoon ; Yu, Chang-Yeon ; Lee, Hyeon-Yong ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 36~42
The immune activation and anticancer activities of the water and ethanol extracts from Artemisia capillaris Thunb. were studied. The growth of human hepatocarcinoma and human gastric cancer cell was inhibited by the addition of
of the water extract, by about 77% and 95%, respectively. The growth of human breast cancer cells was also inhibited by addition of
of both water and ethanol extracts by 88%. The growth of human normal lung cell, HEL299 was inhibited by 15% indicating very low cytotoxicity of both extracts. Overall selectivity of the both extracts on several human cancer cell line was over 2.5. The growth of both human B and T cells was enhanced up to 1.6 to 2.1 times by adding the ethanol extracts. The secretion of cytokines,
and IL-6, from human B cells was also increased showing
, respectively, compared to
of the control. In terms of the immune activity, there was not much difference between water and ethanol extracts of Artemisia capillaris Thunb. It implies that the extraction solvent could not differ the biological activities of the extracts. Based on these results, Artemisia capillaris Thunb. can be developed into a potentially useful cancer chemoprentive agent.
Growth Characteristics and Yield of the Three Species of Genus Angelica
Yu, Hong-Seob ; Park, Chung-Heon ; Park, Chun-Geon ; Kim, Young-Guk ; Park, Hee-Woon ; Seong, Nak-Sul ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 43~46
In genus Angelica, three species have been used and cultivated for medicinal material in orient, A. gigas in Korea, acutiloba in Japan and sinensis in China. A. gigas (Chamdangui) is different from A. acutiloba or A. sinensis in the contents chemical components and their efficacious. In Korea, in particular, A. acutiloba has been cultivated in a small acreage from several decades ago, and recently A. sinensis has been trying to cultivate. A trial of adaptation and cultivation of the three species was performed in different altitudinal regions such as Suwon (50 m of sea level), Jinbu (500 m of sea level) and Taebak (700 m of sea level). A. gigas and acutiloba grew and produced roots successfully at all locations, but A. sinensis could grow only at high altitudinal region, Taebaek. A. sinensis survived 70.3% at Taebaek, but only 45.2% at Jinbu and 3.6% at Suwon. The dry root yield of A. sinensis was as low as 1,600 kg/ha at Taebaek and 1,270 kg/ha at Jinbu comparing farmers' average root yield of A. gigas, 3,000 kg/ha however, no root could be harvested at Suwon. The results, showed it was that A. sinensis could not grow at low altitudinal plane area except high altitude area in Korea. Even though it could grow, the root yield was too low to support the income.
Anti-inflammatory Effect of Patrinia villosa Extract on Proteinase-activated Receptor-2 Mediated Paw Edema
Lim, Jong-Pil ; Cui, Xun ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 47~52
The root of Patrinia villosa Jussieu (Valerianaceae) has long been used for treatment of infectious diseases in Korea. In this study, the anti-inflammatory effect of the Patrinia villosa root water extract (PVWX) was investigated in proteinase-activated receptor-2 (PAR2)-mediated rat paw edema. Paw edema was induced by injection of trypsin or
into hindpaw of rats. PVWX. (10, 50, 100 and 200 mg/kg) was orally administered 1 h before the induction of inflammation. At doses of 50, 100 and 200 mg/kg, PVWX. showed significant inhibition on both change in paw volume and vascular permeability. PVWX. (100 mg/kg) significant1y inhibited PAR2 agonists-induced myeloperoxidase (MPO) activity in paw tissue. These results indicate that PVWX has an anti-inflammatory action in PAR2-mediated paw edema.
Discrimination of Atractylodes Rhizome White Using Anatomical Characteristics and SCAR Markers
Bang, Kyong-Hwan ; Sung, Jung-Sook ; Park, Chung-Heon ; Jin, Dong-Chun ; Park, Chun-Geon ; Yu, Hong-Seob ; Park, Hee-Woon ; Seong, Nak-Sul ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 53~59
Finding a means to discriminate the commercial herb medicines when they were dried and sliced is a very important and imminent project in Korea. To differentiate plant origins and the commercial herb medicines of Atractylodes japonica and A. macrocephala, two discriminative methods using anatomical characteristics and SCAR marker were applied. It was possible to discriminate plant origins and the commercial herb medicines between A. japonica and A. macrocephala by anatomical characteristics: development of periderm, layer of stone cell, distribution of laticiferous vessels, development of xylem fiber in xylem ray, contained quantity of clustered crystals and others. While, two SCAR markers were developed from RAPD clones: SAjR2 (600 bp) from AjR2 and SAmR1 (1,200 bp) from AmR1. These two markers were enough for discrimination plant origins and the commercial herb medicines between A. japonica and A. macrocephala. The result of application of anatomical characteristics and SCAR markers to investigate current status in domestic herb market, Daegu and Kumsan herb market, it was identified to be current herb medicines of A japonica.
Phylogeny of Korean Rhus spp. Based on ITS and rbcL Sequences
Lee, Won-Kyung ; Kim, Myong-Jo ; Heo, Kweon ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 60~66
This study was carried out to confirm the phylogenetic relationships in Korean Rhus species. Sequences from internal transcribed spacers (ITS) of nuclear ribosomal DNA and rbcL gene of chloroplast DNA were determined. Cotinus coggygria was selected as outgroup because it is closest allied with Rhus in Anacardiaceae. Also, ingroup was limited as six Korean Rhus species. ITS 1 sequences in six species of Rhus and one species of Cotinus ranged from 246 to 253 bp and ITS 2 sequences from 234 to 244 bp. Concerning the G+C content of the studied taxa, ITS 1 sequences ranged from 58.0 to 68.13% and ITS 2 from 59.75 to 68.46%. On the other hand, rbcL sequences were same size in the all species examined by 1,428 bp. G+C contents of rbcL sequences were ranged from 43.56 to 43.77% which means there are nearly no different from interspecies each other. Phylogenetic tree strongly supports the colse relationships between R. succedanea and R. sylvestris. Rhus javanica and Cotinus coggygria were also closely allied with each other in ITS and rbcL trees. Therefore, R. javanica was regarded as most primitive species among the Korean Rhus species. ITS 1 region of nuclear ribosomal DNA was suggested as very useful taxonomical marker for genus Rhus.
Discrimination of Angelicae Radix Based on Anatomical Characters
Sung, Jung-Sook ; Bang, Kyong-Hwan ; Park, Chung-Heon ; Park, Chun-Geon ; Yu, Hong-Seob ; Park, Hee-Woon ; Seong, Nak-Sul ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 67~72
For discrimination the origins and the commercial herb medicines of three Angelicae Radixes (Danggui), anatomical characters of leaves, petioles, and root cross-section were investigated and those were compared each other. The key for discrimination of these herb medicines was made by below simple characters: development of periderm, absent and present of collenchyma under the periderm, and distribution of latex tube in cortex. The result of discrimination for the commercial herb medicines based on the discrimination key, Angelicae gjgantis Radix (Angelica Gigas Root), Angelicae Radix (Japanese Angelica Root), and Radix Angelicae Sinensis (Danggui) were correctly identified for Angelica gigas Nakai, A acutiloba Kitagawa, and Angelica sinensis (Oliv.) Diels., respectively. Consequently, anatomical characters could be utilized for useful method to discriminate three Angelicae Radixes (Danggui).
Inhibitory Activity on Angiotensin Converting Enzyme (ACE) of Korean Medicinal Herbs
Lee, Seung-Eun ; Bang, Jin-Ki ; Song, Jin ; Seong, Nak-Sul ; Park, Hee-Woon ; Chung, Hae-Gon ; Kim, Geum-Suk ; An, Tae-Jin ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 73~78
The study was conducted to develop new materials of functional foods from natural resources. Fortyeight medicinal plants were screened on inhibitory activity of angiotensin-converting enzyme (ACE), a protein elevating blood pressure. The water extracts of Armoracia aerial part, Cynanchum radix, Euonymus branch, Phyllostachys stem, Trichosanthes seed, and methanol extract of Silybum aerial part were showed strong inhibitory activity (above 70%) on ACE at the final concentration of
. Among the plant extracts, water extracts of Phyllostachys taeniam and Trichosanthes seed were especially showed strong inhibitory activity (above 25%) at
. These two plants are expected good candidate for development into anti-hypertensive materials.
Inhibitory Activity on Angiotensin Converting Enzyme and Antioxidant Activity of Hovenia dulcis Thunb. Cortex Extract
Lee, Seung-Eun ; Bang, Jin-Ki ; Seong, Nak-Sul ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 79~84
To develop a new functional materials, angiotensin converting enzyme (ACE) inhibitory activity, antioxidant effect and total phenolic content of Hovenia dulcis Thunb. cortex were evaluated. Methanol and water extract of H. dulcis inhibited ACE by 81% and 76%, respectively, at the concentration of
which were similar level with that (85%) of commercial peptide-type ACE inhibitor. Superoxide radical scavenging activity of two extracts
were stronger than that (69%) of ascorbic acid at the final concentration of
. Among the solvent fractions, ether and ethylacetate fraction showed also potent scavenging activities (91% and 85%) for superoxide radical. Inhibitory activities of two extracts on oxidation of human low density lipoprotein (LDL) which were similar with that of
, were higher than 80% at the concentration of
. Total phenol contents of methanol and water extracts were 7.2% and 3.6%, respectively, and that of ethylacetate showed the highest value as 60.8% among the solvent fractions. Therefore, it has been suggested that H. dulcis cortex could be a effective anti-hypertention and antioxidant resource to develope a new functional material.
Growth Characteristics of Curcuma longa L. in Southern Part of Korea
Choi, Seong-Kyu ;
Korean Journal of Medicinal Crop Science, volume 12, issue 1, 2004, Pages 85~88
This study was carried out to obtain basic information on cultivation of Curcuma longa L. in southern part of Korea. The results were summaried as follows. Mulching of both transparent polyethylene film and black polyethylene film improved the soil characters such as soil porosity and soil moisture content. The rate of emergency after winter was increased by mulching. Growth of Curcuma longa L. was accelerated by mulching of transparent polyethylene film and black polyethylene film mulched.