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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Korean Journal of Medicinal Crop Science
Journal Basic Information
Journal DOI :
The Korean Society of Medicinal Crop Science
Editor in Chief :
Volume & Issues
Volume 18, Issue 6 - Dec 2010
Volume 18, Issue 5 - Oct 2010
Volume 18, Issue 4 - Aug 2010
Volume 18, Issue 3 - Jun 2010
Volume 18, Issue 2 - Apr 2010
Volume 18, Issue 1 - Feb 2010
Selecting the target year
Immunoregulatory Effects of Water Extracts of Inonotus obliquus in Carbon Tetrachloride-Induced Liver Damage Animal Model
An, Chi-Sun ; Jin, Hai-Lan ; Jeon, Yun-Hui ; Bak, Jong-Phil ; Kim, Jong-Dai ; Yoon, Jung-Han ; Lim, Beong-Ou ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 1~8
Inonotus obliquus is one of the immune-regulatory substances and is recognized to play the role in the metabolic process of inflammation, allergy and immuntiy. The purpose of this study was to evaluate the effects of water extracts of Inonotus obliquus (IOW) on the liver lymphocyte immune function in the Sprague-Dawley male rats treated with carbon tetrachloride (
) to induce liver damage. Rats were fed with each experimental diet and water for 4 weeks. We found that effects of IOW on interferon-gamma (IFN-
), signal transducer and activator of transcription 1 (STAT1), phospho-signal transducer and activator of transcription 1 (pSTAT1) and GATA-binding protein 3 (GATA-3) were decrease in vivo. Interleukin-4 (IL-4), STAT6, pSTAT6 and T-box expressed in T-cells (T-bet) decreased significantly lower in
+IOW group than the
group. Our data indicated that cytokine protein production were increased in
+IOW group. As a result of this study, we assume that IOW fed could regulate the immuno-modulating functions through regulate the cytokine production capacity activated by liver damage.
Effect of Presowing Seed Treatments on Germination and Seedling Emergence in Taraxacum platycarpum
Jeon, Seung-Ho ; Son, Daniel ; Ryu, Yeong-Seop ; Kim, Seok-Hyeon ; Chung, Jong-Il ; Kim, Min-Chul ; Shim, Sang-In ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 9~14
Several presowing seed treatments have been used to facilitate the seed germination and seedling emergence. The study was performed to design a model of presowing seed treatments in Taraxacum platycarpum. Germination and seedling growth responses to temperature, drying, chilling,
and priming were investigated to know the optimum germination conditions and presowing treatment. The optimum temperature condition for germination and seedling growth were
at dark condition. The seeds exposed to infra red light, however, did not germinate. The moisture content of seeds dried at
for 3.5 hours was returned to the level of unimbibed seeds. The germination of seeds dried under dark condition was better than those dried under infra red light. Prechilling treatment imposed for 6 weeks showed higher germination rate than
treatment or priming. In field test, the highest field emergence was observed in the seeds dried after prechilled for 6 weeks and followed by drying followed by
> low temperature >
priming. Imbibition with 0.1 mM
solution for 2 hours then drying at 35 for 3.5 hour under dark condition was effective to the practical presowing treatment for Taraxacum seeds.
Effects of Lycii fructus and Astragalus membranaceus Mixed Extracts on Immunomodulators and Prevention of Diabetic Cataract and Retinopathy in Streptozotocin-induced Diabetes Rat Model
Jeon, Yun-Hui ; Moon, Jun-Woong ; Kweon, Hyuk-Jung ; Jeoung, Young-Jun ; An, Chi-Sun ; Jin, Hai-Lan ; Hur, Sun-Jin ; Lim, Beong-Ou ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 15~21
This study was conducted to investigate the effects of Lycii fructus and Astragalus membranaceus mixed extracts on immunomodulators and prevention in a streptozotocin-induced diabetes rat model. A total of 28 male rats were divided into four dietary groups and fed a commercial diet (A), commercial diet plus induced diabetes by a streptozotocin (STZ) injection (B), induced diabetes by STZ plus medicinal crop extracts(I&
) diet (C), and medicinal crop extracts (I&
) diet (D). Immunoblotting analyses revealed cytokine expression, and ELISA analyses revealed immunoglobulin E and nitric oxide production. As a results, the tumor necrosis factor-
) and inducible nitric oxide synthase (iNOS) as a inflammatory cytokine were decreased. Interleukin-6 (IL-6) and signal transducer and activation of transcription 3 (STAT3) cytokine related in diabetes expression through JAK/STAT3 pathway were also decreased. Furthermore, immunoglobulin E and nitric oxide production were decreased in the serum and lens, respectively. These results suggest that Lycii fructus and Astragalus membranaceus mixed extracts provide positive effects on immunomodulators and prevention in diabetes and eye disease complications.
Physicochemical Characteristics of 3-Year-Old Ginseng by Various Seeding Density in Direct-Sowing Culture
Seong, Bong-Jae ; Kim, Gwan-Hou ; Kim, Hyun-Ho ; Kim, Sun-Ick ; Han, Seung-Ho ; Lee, Ka-Soon ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 22~27
This study was carried out to investigate the physicochemical characteristics of 3-year-old ginseng (for Samgyetang product) cultured by various seeding density in direct-sowing culture. Ginsengs were cultured by the seeding density, 275, 300, 330 352 and 396 seeds per Kan,
area. Survived rate (82.1%) were the highest in plot of 352 seeds sowed, length and leaf width were high in plot of 300 and 352 seeds. Root yield grain was increased with increase of the seeding density in direct-sowing culture except 352 seeds sowed. Average root weight and diameter were the highest in plot of 352 seeds sowed, 31.6 g and 18.4 mm, respectively. Crude saponin and each ginsenosides content were the highest in plot of 275 seeds sowed. Rg1 content was decreased, Rc and Rb2 content were increased with increase of the seeding density. Total soluble sugar content was the highest in plot of 330 seeds sowed and the lowest in plot of 396 seeds sowed, and oligo- and disaccaride content were high in plot of 330 and 352 seeds sowed. Reological characteristics of ginsengs cultivated according to various seeding density, hardness and springness were high and maximum fracture force was low with decrease of the seeding quantity.
Evaluation of Solvent Extraction on the Anti-Inflammatory Efficacy of Glycyrrhiza uralensis
Yoon, Tae-Sook ; Cheon, Myeong-Sook ; Kim, Seung-Ju ; Lee, A-Yeong ; Moon, Byeong-Cheol ; Chun, Jin-Mi ; Choo, Byung-Kil ; Kim, Ho-Kyoung ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 28~33
Glycyrrhiza uralensis (Leguminosae) is a well-known herbal medicine that has long been valued as a demulcent to relieve inflammatory disorders. To compare the influence of different solvents on the anti-inflammatory efficacy of G. uralensis, we measured the inhibition of pro-inflammatory mediators such as NO, TNF-
in lipopolysaccharide (LPS)-stimulated mouse macrophage RAW 264.7 cells by extracts produced using different solvents (water, methanol, ethanol, or n-hexane). The results showed that methanol was the most effective solvent for the inhibition of both NO and
production in RAW 264.7 cells. However, there was no difference among the extracts for inhibition of TNF-
. Further study must be performed for the analysis of correlation between the anti-inflammatory activity of extracts produced using different solvents and the content of major bioactive compounds in G. uralensis, such as glycyrrhizin and liquiritin. The present study suggests that methanol may be a more appropriate solvent of G. uralensis than other solvents (water, ethanol, and n-hexane) to yield the greatest anti-inflammatory activity for food additives and medicine.
Antioxidant and Anti-diabetes Activity of Extracts from Machilus thunbergii S. et Z.
Xu, Ming Lu ; Hu, Jian He ; Wang, Lan ; Kim, Hyun-Sam ; Jin, Cheng-Wu ; Cho, Dong-Ha ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 34~39
Machilus thunbergii was an important medicinal resource and distributed widely in China. In this study, the bioactivities of dichloromethane fraction (DF) and water fraction (AF) from Machilus thunbergii methanol extract were investigated. Total phenolic contents of DF and AF were 57.90 mg Gal/g and 189.92 mg Gal/g, and total flavonoid contents were 17.34 mg Que/g and 58.38 mg Que/g respectively. The
for DPPH radical scavenging activity of DF and AF were
. Reducing power and hydroxyl radical scavenging activities of AF were higher than those of DF. The
-glucosidase inhibitory activity of AF (
) was higher than that of DF (
). The cell viability was showed that only the DF had anti-proliferation effect on human cancer cell HT-29. These results suggested that both the DF and AF extract of Machilus thunbergii were potential materials for anti-diabetes and functional food for their radical scavenging activity.
ITS-PCR Analysis for the Discrimination of Moutan Cortex
Lee, Jae-Woong ; Kim, Young-Hwa ; Ko, Byoung-Seob ; Ryuk, Jin-Ah ; Oh, Seung-Eun ; Park, Sang-Un ; Lee, Mi-Young ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 40~45
The application of PCR analysis on the herbal medicine Moutan Cortex (Paeonia suffruticosa Andrews) was evaluated by the comparison of the genetic relationship based on the DNA sequence with Paeoniae Radix (Paeonia lactiflora Pallas) following development of specific primers. Moutan Cortex and Paeoniae Radix were distinguished through the PCR analysis based on the internal transcribed spacer (ITS-PCR) from nuclear ribosomal DNA region. The 294 bp PCR products both of Moutan Cortex and Paeoniae Radix was amplified by MIF1 and MIR1. And a Moutan Cortex specific 225 bp PCR amplification product was amplified by MIF2 and MIR1 primers. The 225 bp sequence could be successfully amplified from Mortan Cortex of dried herbal preparations. PCR analysis based on ITS (ITS-PCR) may be an efficient tool for the discrimination of Moutan Cortex.
Studies on Major Agronomic Characteristics of Korean Artemisia annua L.
Lee, Jeong-Hoon ; Park, Chung-Berm ; Park, Chun-Geon ; Son, Yeong-Deuk ; Moon, Seong-Gi ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 46~50
In order to development medicinal Artemisia herbs of high quality, Korean A. annua L. were investigated with its ecological and morphological characteristics, and basic statistical data of agronomic characteristics. This species, which is annual herb, is mainly distributed to marginal land, riverside, roadside, grassland. Ecological niche is low species in competition of the others. Its pollination is basically anemogamous, but is frequency pollinated by insects. This species is characterized as tap root, 1~3 pinnate compound leaf of ovate or narrowly ovate, stem is green, erect and solitary. Inflorescence is paniculate, receptacle is not hair. Capitulum, consist of ray floret and disk floret, is subglobose shape. Additionally, this species could be easily discriminated from related Artemisia herbs by the capitulum size. Ray floret is female, disk floret is bisexual. Flowering season is from August to October. Seed is achene unattached hair. Stem length ranged from 179 cm to 225 cm, and stem diameter and number of branch were
, respectively. Length and width of leaf were
, and leaf number of main stem were
, respectively. Fresh weight of aerial parts and root were
, and its dry weight were
Changes of Growth Characteristics and Ginsenoside Content by Growth Stages and Different Planting Position in Panax ginseng C.A. Meyer
Kwon, Soon-Goo ; Lee, Chung-Yeol ; Oh, Dong-Joo ; Li, Guan-Ying ; Cha, Sun-Woo ; Lee, Seong-Woo ;
Korean Journal of Medicinal Crop Science, volume 18, issue 1, 2010, Pages 51~55
This study was conducted to investigate the effect of planting position on the growth characteristics, yield and ginsenoside content in Panax ginseng C.A. Meyer at different growth stages. Referring to shoot growth characteristics, stem length, stem diameter and leave area were higher at front than rear, increasing as the proceeding of growth stages. But a lower chlorophyll contents was caused at front compared to rear and decreased as the proceeding of growth stages contrarily. According to root characteristics, root length and main body length were higher at front, with a positive correlation to growth stages, which was also shown on fresh root weight and dry root weight with the maximum in August. Meanwhile, the effect of planting position on ginsenoside content could also be definite by the highest content at front showing high light intensity, increasing as the proceeding of growth stages as well.