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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Korean Journal of Medicinal Crop Science
Journal Basic Information
Journal DOI :
The Korean Society of Medicinal Crop Science
Editor in Chief :
Volume & Issues
Volume 19, Issue 6 - Dec 2011
Volume 19, Issue 5 - Oct 2011
Volume 19, Issue 4 - Aug 2011
Volume 19, Issue 3 - Jun 2011
Volume 19, Issue 2 - Apr 2011
Volume 19, Issue 1 - Feb 2011
Selecting the target year
Yield and Quality Characteristics of Ginseng's First Byproducts
Kim, Gwan-Hou ; Seong, Bong-Jae ; Kim, Sun-Ick ; Han, Seung-Ho ; Kim, Hyun-Ho ; Lee, Ka-Soon ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 313~318
DOI : 10.7783/KJMCS.2011.19.5.313
This study was carried out to utilize the byproducts (flower, immature and mature berry, leaf and stem) of ginseng. Yield of byproducts were
in immature berry,
in mature berry,
in leaf, and
in stem per
, ginseng root
/drybasis. The total saponin contents of ginseng byproducts and root are
mg/g, respectively. The main ginsenoside of all byproducts was Re and the highest content was
mg/g in mature berry. But flower and berry was not detected Rf and Rh1, respectively. Total polyphenolic compound content on mature berry was the highest,
, after, immature berry > leaf > flower > root > stem order. The DPPH radical scavenging activity on mature berry was the highest,
), and the others were the same order of polyphenolic compound and ginsenoside content on byproducts.
Effect of Lythrum salicaria L. Ethanol Extract on Lipid Metabolism and Anti-Obesity in Rat Fed High Fat Diet
Kim, Hee-Yeon ; Lim, Sang-Hyun ; Kwon, Chang-Ju ; Park, Yu-Hwa ; Lee, Kwang-Jae ; Park, Dong-Sik ; Kim, Kyung-Hee ; Kim, Song-Mun ; Park, Chung-Berm ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 319~324
DOI : 10.7783/KJMCS.2011.19.5.319
This study was carried out to investigate the effect of Lythrum salicaria L. ethanol extract on anti-obesity effects in rat fed a high fat diet for 8 weeks to induce obese rat model. Male SD rats were divided into normal group, control (high fat diet) group, positive control (Garcinia Cambogia extracts) group, high fat group supplemented with ethanol extracts of Lythrum salicaria L. (EELS). The body weight gain and control (high fat diet) were increased by a high fat diet, but decreased in the EELS. At the end of the experiment, the body weight in high fat diet groups was higher than that of normal diet group, while the body weights of EELS and positive control group were significantly reduced by 16.62%, as compared with that of high fat diet group (p < 0.05). The levels of serum triglyceride, total cholesterol in EELS group were significantly decreased as compared with high fat diet group (p < 0.05). The liver and mesenteric adipose tissue weights of control (high fat diet) increase than that for normal group, whereas EELS and positive control group were significantly decreased (p < 0.05). Levels of triglyceride in liver were significantly lower in EELS group than those in high fat diet group (p < 0.05). These results indicate that Lythrum salicaria L. extract may improve lipid metabolism and reduce fat accumulation and body weight.
Screening of Biological Activities to Different Ethanol Extracts of Rubus coreanus Miq.
Kwon, Ji-Wung ; Lee, Hee-Kwon ; Park, Hee-Jeon ; Kwon, Tae-Oh ; Choi, Heh-Ran ; Song, Ji-Young ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 325~333
DOI : 10.7783/KJMCS.2011.19.5.325
This study was carried out to evaluate biological activities to different ethanol extracts from unripened and ripened fruit (Rubus coreanus Miq.). 25% to 75% ethanol extracts of unripened and ripened fruits were similar to extract yield respectively. Yield of ethanol extract of ripened fruit were approximately 3 times higher than that of unripened fruit. 75% ethanol extract of unripened fruit showed the highest contents of total polyphenol (
mg/g) and total flavonoid (
mg/g). Contents of total polyphenol and total flavonoid of unripened fruit were about 2 times higher than those of ripened fruit.
values of DPPH radical scavenging activity and linoleic acid peroxidation inhibition activity of BHA and
respectively, but 75% ethanol extract of unripened fruit showed the lowest
among other all extracts.
values of LDL (low density lipoprotein) oxidation inhibition activity and
-glucosidase inhibitory activity of 75% ethanol extract of unripened fruit showed the lowest
among other all extracts respectively. Specifically, 75% ethanol extract of unripened fruit has relatively better biological activities than other ethanol extracts, it could be potentially used as bioactive source for health functional foods.
Effect of Plant Part Extracts of Lythrum salicaria L. on Chronically Alcohol-Administrated Rat
Lee, Seung-Eun ; Kim, Geum-Soog ; Lee, Jeong-Hoon ; Kang, Yong-Ku ; Lee, Eun-Suk ; Choi, Je-Hun ; Lee, A-Reum ; Park, Su-Jin ; Noh, Hyung-Jun ; Kim, Seung-Yu ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 334~340
DOI : 10.7783/KJMCS.2011.19.5.334
The study was done to investigate the effects of the extracts from the different parts of Lythrum salicaria (LS) on liver protective activities in chronically alcohol-treated rats. SD male rats except normal animals were administrated with alcohol (
of 30%~40% ethanol/kg/day) and the extracts (300 mg/kg/day) for 10 weeks. Chronic alcohol administration decreased body weight, high density lipoprotein (HDL)-cholesterol and the reduced form-glutathione (GSH), whereas increased the ethanol content, glutamic-oxaloacetic transaminase (GOT), total cholesterol, low density lipoprotein (LDL)- cholesterol, triglyceride in blood/serum and the ratio of the oxidized form of glutathione (GSSG) and total GSH (GSSG/total GSH) in liver tissue. Groups treated with the extracts of leaf, root and stem, showed decrease in GOT, total cholesterol and GSSG/total GSH and increase in hepatic aldehyde dehydrogenase (ALDH), total GSH and serum albumin. Administration with the root extract of LS decreased blood ethanol content compared with the other part extracts. But, serum triglyceride values in rats treated with root and stem extract were higher than that of the negative control animals. Flower extract-fed group showed decrease in body weight and serum triglyceride, but increase in the ratio of GOT and glutamic-pyruvic transaminase (GPT), and GSSG/total GSH. From the results, we conclude that the extracts of root and leaf among the plant parts of LS might be useful for the amelioration of the chronic alcohol-induced liver demage of rat.
Antioxidant Activities of Rehmannia glutinosa by Traditional Methods
Kim, Hyo-Jin ; Lee, Ji-Yeon ; You, Bo-Ram ; Doh, Eun-Soo ; Kim, Mee-Ree ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 341~346
DOI : 10.7783/KJMCS.2011.19.5.341
The objective of this study was to evaluate antioxidant activities of Rehmannia glutinosa (Raw Jihwang) by traditional method. The total phenol content of Rehmannia radix Preparata (the final cycle of Jihwang) was increased to 205%, compared with Rehmannia glutinosa. Antioxidant activities, determined by ferric-reducing antioxidant potential (FRAP), 2,2'-azinobis(3 ethybenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, 1,1-diphenyl-2-picrydrazyl (DPPH) and hydroxyl radical scavenging activities, increased remarkably as the number of steaming-drying cycles increased. Especially, FRAP value increased 285%. Also,
values for DPPH and hydroxyl radical scavenging activities of the final 9th-cycling product, decreased 48.4% and 76%, respectively, compared with those of Rehmannia glutinosa. Our result was suggested that antioxidant activities of Rehmannia radix Preparata improve according to the increasing number of steaming-drying cycles.
Analysis of Genetic Polymorphism of Korean Ginseng Cultivars and Foreign Accessions using SSR Markers
Bang, Kyong-Hwan ; Jo, Ick-Hyun ; Chung, Jong-Wook ; Kim, Young-Chang ; Lee, Jei-Wan ; Seo, A-Yeon ; Park, Jong-Hyun ; Kim, Ok-Tae ; Hyun, Dong-Yun ; Kim, Dong-Hwi ; Cha, Seon-Woo ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 347~353
DOI : 10.7783/KJMCS.2011.19.5.347
In this study, simple sequence repeat (SSR) analyses were utilized for evaluation of genetic diversity and discrimination of 17 accessions. Five cultivars, which were developed from Korea, and 12 foreign accessions, which were collected from China, Japan, Russia and USA, were evaluated by nine markers out of 22 SSR markers. A total of 39 alleles were detected, ranging from 2 to 8, with an average of 4.3 alleles per locus. The expected heterozygosity and PIC values were 0.627 and 0.553, with a range from 0.21 (GB-PG-078) to 0.76 (GB-PG-142) and from 0.19 (GB-PG-078) to 0.70 (GB-PG-142), respectively. Four makers out of nine SSR markers, GB-PG-026, GB-PG-043, GB-PG-142 and GB-PG-177, were selected as key factors for discrimination of Korean ginseng cultivars and foreign accessions. All of Korean ginseng cultivars and foreign accessions were individually by the combination of four SSR markers. Consequently, the SSR markers developed in this study may prove useful for the evaluation of genetic diversity and discrimination of Korean ginseng cultivars and foreign accessions.
Changes of Components and Quality in Gastrodiae Rhizoma by Different Dry Methods
Choi, So-Ra ; Jang, Ik ; Kim, Chang-Su ; You, Dong-Hyun ; Kim, Jong-Yeob ; Kim, Young-Gook ; Ahn, Young-Seob ; Kim, Jeong-Man ; Kim, Young-Sun ; Seo, Kyoung-Won ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 354~361
DOI : 10.7783/KJMCS.2011.19.5.354
In order to product dry goods of Gastrodiae Rhizoma with high quality, tubers were treated with various dry methods such as cutting, drying methods and steaming. In cutting than no cutting, they were shown shorter drying hours and lower drying yield. Drying hours in freeze drying was shorter than those of hot air and far-infrared ray. Total polyphenol content was higher in cutting than no cutting. According to steaming, it was increased in freeze drying but decreased rapidly in the other dry methods. Among all treatments, hot air dry treatment with cutting and no steaming had the highest total polyphenol content. Gastrodin and 4-hydroxybenzyl alcohol contents generally were similar or higher in cutting than no cutting. By steaming, gastrodin content in freeze drying was decreased but 4-hydroxybenzyl alcohol content was increased. But hot-air and infrared ray dry, they were shown opposite results. Gastrodin and 4-hydroxybenzyl alcohol contents showed opposite reaction to each other and were shown various response by dry methods.
Nitric Oxide Production Inhibitory and Scavenging Activity and Tyrosinase Inhibitory Activity of Extracts from Taraxacum officinale and Taraxacum coreanum
Im, Do-Youn ; Lee, Kyoung-In ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 362~367
DOI : 10.7783/KJMCS.2011.19.5.362
The study was conducted to investigate functional materials as skin whitening and anti-inflammatory agent from Taraxacum officinale and Taraxacum coreanum. The total polyphenol and flavonoid content in the ethanol extract of Taraxacum officinale were found to be 64.07mg/g and 32.46mg/g, respectively. In tyrosinase inhibitory activity, the hot water extract of Taraxacum coreanum was higher than the other extracts. However, in nitric oxide (NO) scavenging ability, the ethanol extract of Taraxacum coreanum was higher than the other extracts. the ethanol extract of Taraxacum coreanum showed strong NO production inhibitory effect in lipopolysaccharide (LPS)-stimulated Raw 264.7 cell. In the cell viability measurement by MTT assay and the lactate dehydrogenase (LDH) assay against L929 cell, the extracts were exhibited fine cell viabilities and normal LDH release levels as nontoxic result in sample concentration of
. As a result, the ethanol extract and the hot water extract of Taraxacum coreanum could be applicable to functional materials for anti-inflammatory and skin whitening related fields, respectively.
Antioxidative and Nitric Oxide Production Inhibitory Activities of Lespedeza bicolor Stem Extracts Depending on Solvents
Lee, Kyoung-In ; Yang, Sun-Ah ; Kim, Sun-Min ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 368~372
DOI : 10.7783/KJMCS.2011.19.5.368
In this study, we investigated on antioxidative activity and nitric oxide production inhibitory activity of various solvent extracts of Lespedeza bicolor. The total polyphenol content of the methanol extract was 192.6 mg/g and flavonoid content of the acetone extract was 40.6 mg/g, as the highest content. In DPPH radical scavenging ability,
values of the ethanol and methanol extract were exhibited
, respectively. However, in nitric oxide(NO) scavenging ability,
values of the acetone was exhibited
as the highest activity. Moreover, the acetone extract showed strong NO production inhibitory effect in lipopolysaccharide(LPS)-stimulated Raw 264.7 cell. In the cytotoxicity measurement by MTT assay, the extracts were exhibited Raw 264.7 cell viabilities of 92.57~129.04% as nontoxic result in concentration of
. As a result, the acetone extract of L. bicolor could be applicable to functional materials for anti-inflammatory related fields.
Suppression Effect of the Inflammatory Response in Macrophages by Paeoniae Radix Rubra Extracts
Bak, Jong-Phil ; Son, Jung-Hyun ; Kim, Yong-Min ; Jung, Joon-Hee ; Leem, Kang-Hyun ; Lee, Eun-Yong ; Kim, Ee-Hwa ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 373~379
DOI : 10.7783/KJMCS.2011.19.5.373
Paeoniae Radix Rubra is a preparation consisting of desiccated roots of Paeonia lactiflora PALL (belonging to Ranunculaceae). Paeoniae Radix Rubra is used as a medicinal herb in Asian countries to treat many diseases. Ethanol- or water-based extracts of Paeoniae Radix Rubra were prepared and tested on RAW 264.7 cells, a murine macrophage cell line. The expression of some pro-inflammatory proteins, including inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), extracellular signal-regulated kinase 1/2 (ERK1/2) and phosphorylated ERK1/2 was detected by Western blot analyses, while PGE2 expression was quantified by ELISA. Both the water and ethanol extracts of Paeoniae Radix Rubra suppressed LPS-induced nitric oxide (NO) production and exhibited cell toxicity in accordance with increased NO production. Also, both extracts reduced the expression of COX-2 and iNOS, and inhibited phosphorylation of ERK1/2 in LPS-stimulated RAW 264.7 cells. Extracts prepared from Paeoniae Radix Rubra contain anti-inflammatory agents that inhibit the iNOS and MAPK pathways.
Inhibitory Effects of Angelicae Dahuricae Radix Extract on COPD induced by Cigarette Smoke Condensate and Lipopolysaccharide in Mice
Kwak, Ho-Geun ; Lim, Heung-Bin ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 380~387
DOI : 10.7783/KJMCS.2011.19.5.380
This study was carried out to investigate the inhibitory effect of Angelicae Dahuricae Radix (ADR) extract on chronic obstructive pulmonary disease (COPD) induced by cigarette smoke condensate (CSC) and lipopolysaccharide (LPS) in mice. COPD was induced by intratracheal instillation of LPS and CSC 5 times for 12 days; this increased airway hyperresoponsiveness (AHR) and inflammatory cells in bronchoalveolar lavage fluid (BALF). ADR extract was administered orally at a dose of 50 and 200 mg/kg. The concentration of imperatorin, a major component of ADR and therefore used as a measure of quality control, was
. Treatment of the mice with ADR extract (50 and 200 mg/kg) alleviated AHR and reduced inflammatory cell counts. Treatment with cyclosporin A (CSA; 10 mg/kg) also modulated AHR and reduced inflammatory cells effectively. Compared with CSA treatment, treatment with ADR (50 mg/kg) extract reduced neutrophil and
cell counts by 22.67% and 44.92%, respectively. In addition, compared with CSA treatment, treatment ADR 200 mg/kg reduced neutrophils,
cells, by 32.10%, 83.17% and 82.11%, respectively. These results indicate that ADR extract may have an inhibitory effect on COPD induced by LPS and CSC in mice.
Antioxidant and Cell Activity Using Extracts of Mume Fructus
Bae, Yu-Kyung ; Choe, Tae-Boo ;
Korean Journal of Medicinal Crop Science, volume 19, issue 5, 2011, Pages 388~394
DOI : 10.7783/KJMCS.2011.19.5.388
Mume fructus is the roasted fruits of Prunus mume and has been used as traditional chinese medicine. In this study, mume fructus extracts were prepared by three different methods including hot water extract (sample1), fermentation extract using Lactobacillus (Sample2-LP and sample-LA) and ethanol extract (sample3). Total polyphenol and flavonoid contents were improved by fermentation process, compared to water extract. Sample 3 showed the highest activity in DPPH radical scavenging. The cytotoxicity of the sample 2-LP was in the range of 83.3% cell viability at
concentration. Mume fructus extracts in a concentration-dependent manner inhibited melanogenesis and NO synthesis was inhibited. Specifically, the extracts fermented by L. plantarum (sample2-LP) showed higher anti-oxidant activity, anti-inflammatory and skin whitening activity than other extracts. It suggests that sample 2-LP could be potentially used as a resource of materials for functional cosmetics.