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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Maxillofacial Plastic and Reconstructive Surgery
Journal Basic Information
Journal DOI :
Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
Editor in Chief :
Volume & Issues
Volume 31, Issue 6 - Nov 2009
Volume 31, Issue 5 - Sep 2009
Volume 31, Issue 4 - Jul 2009
Volume 31, Issue 3 - May 2009
Volume 31, Issue 2 - Mar 2009
Volume 31, Issue 1 - Jan 2009
Selecting the target year
EFFECT OF ENAMEL MATRIX DERIVATIVE (EMD,
) ON THE DIFFERENTIATION OF CULTURED HUMAN PERIODONTAL LIGAMENT CELLS AND MESENCHYMAL STEM CELLS
Park, Sang-Gyu ; Jue, Seong-Suk ; Kwon, Yong-Dae ; Choi, Byung-Joon ; Kim, Young-Ran ; Lee, Baek-Soo ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 281~286
Introduction: Enamel matrix derivative (EMD) is a protein which is secreted by Hertwig root sheath and plays a major role in the formation of cementum and attachment of peridontium. Several studies have shown that EMD promoted the proliferation and differentiation of preosteoblasts, osteoblasts and periodontal ligament cells in vitro: however, reports showing the inhibition of osteogenic differentiation by EMD also existed. This study was designed to simultaneously evaluate the effect of EMD on the two cell lines (human mesenchymal stem cells: hMSC, human periodontal ligament derived fibroblasts: hPDLCs) by means of quantitative analysis of some bone related matrices (Alkaline phosphatase : ALP, osteopontin ; OPN, osteocalcin ; OC). Materials and Methods: hMSCs and hPDLCs were expanded and cells in the 4
6 passages were adopted to use. hMSc and hPDLCs were cultured during 1,2,7, and 14 days with 0, 50 and 100
of EMD, respectively. ALP activity was assessed by SensoLyte ALP kit and expressed as values of the relative optical density. Among the matrix proteins of the bony tissue, OC and OPN were assessed and quantification of these proteins was evaluated by means of human OC immunoassay kit and human OPN assay kit, respectively. Results: ALP activity maintained without EMD at
day. The activity increased at
day but decreased at
day. EMD increased the activity at
day in the hPDLCs culture. In the hMSCs, rapid decrease was noted in
days without regard to EMD concentrations. Regarding the OPN synthesis in hPDLCs, marked decrease of OPN was noted after EMD application. Gradual decrease tendency of OPN was shown over time. In hMSCs, marked decrease of OPN was also noted after EMD application. Overall concentration of OPN was relatively consistent over time than that in hPDLCs. Regarding the OC synthesis, in both of hPDLCs and hMSCs, inhibition of OC formation was noted after EMD application in the early stages but EMD exerted minimal effect at the later stages. Conclusion: In this experimental condition, EMD seemed to play an inhibitory role during the differentiation of hMSCs and hPDLCs in the context of OC and OPN formation. In the periodontium, there are many kinds of cells contributing to the regeneration of oral tissue. EMD enhanced ALP activity in hPDLCs rather than in hMSCs and this may imply that EMD has a positive effect on the differentiation of cementoblasts compared with the effect on hMSCs. The result of our research was consistent with recent studies in which the authors showed the inhibitory effect of EMD in terms of the differentiation of mineral colony forming cells in vitro. This in vitro study may not stand for all the charateristics of EMD; thus, further studies involving many other bone matrices and cellular attachment will be necessary.
EFFECT OF DEXAMETHASONE CONCENTRATIONS ON OSTEOGENIC ACTIVITY OF CULTURED HUMAN PERIOSTEAL-DERIVED CELLS
Kim, Jong-Ryoul ; Park, Bong-Wook ; Lee, Chang-Il ; Hah, Young-Sool ; Kim, Deok-Ryong ; Cho, Yeong-Cheol ; Sung, Iel-Yong ; Byun, June-Ho ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 287~293
Long-term treatment with glucocorticoid leads to the development of osteoporosis and osteonecrosis. In contrast to the marked inhibitory effect of pharmacological doses of glucocorticoids on bone formation, the relationship between physiological concentrations of glucocorticoids and osteoprogenitor cell proliferation and phenotypes has not been elucidated yet. In addition, the effects of dexamethasone treatment on the proliferation and osteoblastic differentiation of osteoprogenitor cells are also controversial. The purpose of this study was to examine the effects of dexamethasone on the proliferation and osteoblastic differentiation of periosteal-derived cells. Periosteal-derived cells were obtained from mandibular periosteums and introduced into the cell culture. After passage 3, the cells were further cultured for 21 days in the osteogenic induction medium with different dexamethasone concentrations of 0, 10, and 100 nM. The proliferation and osteoblastic phenotypes of periosteal-derived cells were promoted in dexamethasone-treated cells than in untreated cells. Among the dexamethasone-treated cells, cell proliferation was slightly greater in 10 nM dexamethasone-treated cells than in 100 nM dexamethasone-treated cells. Histochemical staining and the bioactivity of alkaline phosphatase (ALP) were higher in 100 nM dexamethasone-treated cells than in 10 nM dexamethasone-treated cells. Similarly, von Kossa-positive mineralization nodules and calcium content were also more evident in 100 nM dexamethasone-treated cells than in 10 nM dexamethasone-treated cells. These results suggest that dexamethasone enhances the in vitro osteoblastic differentiation of periosteal-derived cells. The present study also demonstrates that higher dexamethasone concentrations reduce the in vitro proliferation of periosteal-derived cells.
CHANGES IN HYOID BONE AND TONGUE POSITIONS, AND ORAL CAVITY VOLUME AFTER MANDIBULAR SETBACK BY SAGITTAL SPLIT RAMUS OSTEOTOMY
Liang, Shan-Shan ; Chu, Yeon-Gyu ; Choi, So-Young ; Lee, Sang-Han ; Park, In-Suk ; Deng, Fang-Cheng ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 294~305
Purpose: This retrospective study evaluated the changes in hyoid bone and tongue positions as well as oral cavity volume after mandibular setback by BSSRO. Materials and Methods: 18 Koreans who underwent BSSRO to correct mandibular prognathism were studied. Lateral cephalograms were taken and traced preoperatively (T0), immediately (T1) and approximately 6 months postoperatively (T2). Submentovertex radiograghs were taken and traced before surgery (T0) and about 6 months after surgery (T2). The area and volume of oral cavity, the vertical and horizontal dimensions of the hyoid bone and tongue dorsum were measured. Results: Mandibular setback surgery resulted in a significant reduction of lower oral cavity volume. The hyoid bone displaced posteroinferiorly immediately after surgery, and it tended to return to its original vertical position at 6 month after mandibular setback by BSSRO. The retropalatal space around tongue was maintained and the retrolingual space around tongue was reduced immediately postoperatively. The readaptation of tongue was not evident for that the follow up period was not long enough. No significant statistical correlations between the amounts of mandibular setback and the changes of oral cavity volume were observed. Conclusion: Mandibular setback surgery resulted in a significant reduction of lower oral cavity volume, which was most likely attributable to the posterior movement of the mandible. More subjects and long-term observations should be performed to assess the changes of oropharyngeal configuration following mandibular setback surgery.
CLINICAL STUDY ON SURVIVAL RATE OF OSSEOINTEGRATED IMPLANTS
Choi, Ji-Yeon ; Koh, Se-Wook ; Ryu, Hwun-Wook ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 306~313
Objectives: The aim of the present review was to evaluate survival rate and various factors associated with survival of osseointegrated implants. Patients and methods: The clinical comparisons were performed to evaluate survival rate of 794 endosseous implants that had been inserted between 2004 through 2008 in relation to sex and age of patients, position of implant, implant system and surface characteristics, length and diameter of implant, and bone graft technique. Results: The survival rate of implant was 94.3% in posterior area of maxilla and 98.6% in posterior area of mandible by position of implant, a statistically significant difference. As to diameter of implant, survival rate was 98.4% between the 4.0 and 4.5 mm and 75.0% in larger than 5.0 mm, that was statistically significant difference. There was a statistically significant difference regard to bone graft and surgical technique. The implant survival rate was 89.0% in a placement site which performed sinus lifting, and in case of implant placement with guided bone regeneration technique and without bone grafting was 97.6% and 100% each. Conclusion: According to these findings, this study establishes a relationship between survival rate of implant and position, surface characteristics, diameter of implant and bone graft technique.
PRELIMINARY STUDY ON "RIDGE SPLITTING TECHNIQUE" IN HORIZONTALLY DEFICIENT ALVEOLAR RIDGE
Park, Young-Ju ; Nam, Jeong-Hun ; Song, Jun-Ho ; Yeon, Byung-Moo ; Noh, Kyung-Lok ; Pang, Eun-O ; Chung, Jae-An ; Shin, Jin-Eob ; Kang, Eung-Seon ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 314~318
The aim of this study was to evaluate the clinical applicability of a ridge splitting technique for reconstruction of narrowed edentulous alveolar ridges for dental implantation. 41 patients with 47 edentulous areas were included in this study. After corticotomy of a rectangular buccal segment and about 3-4 weeks healing period, the alveolar ridge was splitted, implant was placed. The initial ridge width varied between 2.5 and 7.0mm, average was 3.99mm. 68 dental implants were placed, and the gap between the implants and the bone is filled with various bone graft material, or none. All splitted sites showed sufficient bone volume for insertion of the implants at the moment of implantation. Over 1 year of follow-up period, five implants(7.3%) had mobility in two patients, among them, 2 implants(2.9%) sustained infection and removed. And any other complications were not noted. Our conclussion is that ridge splitting of the narrow edentulous area is a reliable and safe procedure in horizontally deficient ridges.
ORAL REHABILITATION WITH MANDIBULAR ANTERIOR SEGMENTAL OSTEOTOMY AND IMPLANTATION: A CASE REPORT
Moon, Chul-Woong ; Kim, Su-Gwan ; Kim, Hak-Kyun ; Moon, Seong-Yong ; You, Jae-Seek ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 319~324
Kole's Anterior segmental osteotomy of the mandible is commonly used to close an anterior open bite, to depress an elevated anterior dentoalveolar segment, or to retrude or advance a dentoalveolar segment. The procedure is often combined with an anterior maxillary segmental osteotomy to correct bimaxillary protrusion. We report 53-year-old woman who the extruded state of mandibular anterior alveolar segment was corrected using an mandibular anterior alveolar segmental osteotomy and dental implantation of the anterior maxilla. We planned to remove the old prosthesis, and then perform an anterior mandibular segmental osteotomy and implant restoration of the anterior maxilla. We suggest that anterior segmental osteotomy is very useful for rehabilitating edentulous patients with malaligned alveolar segment.
A CASE REPORT OF IMPLANT PLACEMENT IN DISTRACTION-AUGMENTED ALVEOLAR BONE OF THE MANDIBLE
Ryu, Hyun-Wook ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 325~329
Objective : This is to report the effectiveness of intraoral distraction osteogenesis, iliac bone graft for alveolar augmentation in the extremely atrophied alveolar defects after infected allobone grafted area. Subjects and Methods : Anterior segmental osteotomy was performed and the trans-oral alveolar distractors (Martin, Germany) were applied in patient with the severe acquired anterior mandibular and mandibular defect after ameloblastoma enucleation. Iliac bone grafts were performed in defect sites and distraction osteogenesis were treated. After latent period for 1 week, the osteomized alveolar segments were distracted by 0.75 mm a day (0.25 mm/1 turn) for 10 days The consolidation period was about 12 weeks. Thereafter, 2 titanium threaded implants were simultaneously installed with removal of distractor. For oral rehabilitiation, The implants were installed in maxilla, mandible. It was tested with clinically and radiographically. Results : Amounts of acquired alveolar bone were 10 mm with the increased width of the ridge crests and soft tissue expansion. Dental implants installated on the augmented alveolar ridges in 12 weeks after distraction were confirmed as in good osseointegration and in good function without any complications. Conclusion : Intraoral distraction osteogenesis can be a good option for alveolar ridge augmentation of the severely atrophied ridges and soft-tissue defects.
IMMEDIATE IMPLANT PLACEMENT AFTER EXTRACTION OF RETAINED DECIDUOUS TEETH AND IMPACTED CANINES: REPORT OF A CASE
Yoo, Ji-Yeon ; Kim, Yeo-Gab ; Lee, Baek-Soo ; Kwon, Yong-Dae ; Choi, Byung-Joon ; Kim, Young-Ran ; Baek, Jin ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 330~333
Alveolar bone resorption after extraction impairs the necessary bone volume and complicates the case for implant surgery and aesthetic implant prosthesis. Immediate implant surgery after extraction decreases the number of surgical procedures and the duration of treatment, while allowing minimum alveolar bone resorption and preserving the residual bone volume. Although immediate implant holds many advantages such as preservation of hard and soft tissue around the extraction socket, greater implant survival rate and higher patient satisfaction, various complications and high failure rate are discouraging factors for the clinicians. In this case report, severe alveolar bone resorption with soft tissue changes were predicted after the extraction of prolonged retained deciduous incisors and impacted maxillary canines and thus decided on immediate implant procedure. Immediate implant surgery after extraction was carried out with minimal bone reduction and tapered wide-neck implant to establish initial stability. Simultaneous bone graft was done by filling the defect area with iliac cancellous bone with additional onlay-type bone graft and absorbable membrane on the labial bone for upper lip support. A stable and esthetic result was obtained with shortened treatment period.
IMMEDIATE PLACEMENT OF IMPLANT FOLLOWING EXTRACTION OF IMPACTED SUPERNUMERARY TEETH AND PERMANENT TEETH : A CASE REPORT
Kwon, Jun ; Yoon, Kyu-Ho ; Park, Kwan-Soo ; Cheong, Jeong-Kwon ; Shin, Jae-Myung ; Choi, Min-Hye ; Na, Hye-Jung ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 334~338
Supernumerary teeth are extra teeth or tooth-like structures which may have either erupted or unerupted in addition to the 20 deciduous teeth and the 32 permanent teeth. Clinicians sometimes confront unerupted supernumerary teeth where implants would be placed. Many clinicians consider immediate placement of implant into an extracted socket as an effective technique compared to the conventional method of waiting several months for bone healing, because of the advantages such as reduction of treatment period, preservation of alveolar bone and soft tissue, etc. We could hardly find the case of immediate placement of implant after extraction of impacted supernumerary teeth and permanent teeth together. Therefore we report the case of immediate implantation following extraction of impacted supernumerary teeth and poor periodontal conditioned permanent teeth.
METASTASIS OF ADENOID CYSTIC CARCINOMA OF THE MINOR SALIVARY GLAND TO THE SCALP : A CASE REPORT
Cho, Sung-Min ; Pyo, Sung-Woon ; Park, Ji-Young ; Kim, Jean-A ; Lee, Kyung-Ji ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 339~342
Adenoid cystic carcinoma(ACC) is the second most common malignant neoplasm in the salivary gland. In spite of ACC shows slowly growing nature, it is sometimes highly detrimental that it readily invades adjacent tissues and metastasize to distant organs at the early stage of disease. Hence, treatment outcome may be misfortunate due to wide regional infiltration, pathognomonic perineural spread and the tendency of hematogenous metastasis. We present a unusal case of ACC of the scalp in which the patient initially presented with bumpy mass of the scalp who had been diagnosed as the primarily developed ACC of the right hard palate that extended to infratemporal fossa, nasal cavity, and paranasal sinuses and had been treated by total excision and post-operative chemotherapy and radiation therapy for 10 years ago. Although this lesion occured at the scalp, which is a frequent site of primary dermatologic ACC, its histomorphology was the same with that of previous tumor. Complete clinical examination showed no recurrence sign at the primary site and suggested the scalp as a sole treatment failure site. Accordingly, it would be reasonable to consider the present case as either a scalp metastasis or a second primary lesion of salivary gland ACC.
KAPOSI'S SARCOMA OF MAXILLARAY GINGIVA IN SYSTEMIC LUPUS ERYTHEMATOSUS
Kim, Il-Kyu ; Cho, Hyun-Young ; Chang, Keum-Soo ; Park, Seung-Hoon ; Park, Jong-Won ; Sasikala, Balaraman ; Kim, Joon-Mee ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 343~348
Kaposi's sarcoma was first descrided by Kaposi in 1872 as an idiopathic multiple hemorrhagic sarcoma. Its clinical features revealed to be erythematous red or purple macule started out, and developing into palpable dome-shaped nodules. Etiology is not defined to detail at present. Kaposi's sarcoma is classified to 4 categories; Classical, African, Epidemic and Immunosuppressive type. Epidemic categories is found approximately 20% of all AIDS patients and has strong predilection for head and neck region. The first case of immunosuppresive type Kaposi's sarcoma in patients with kidney transplants was reported in 1969. Kaposi's sarcoma accounts for 5% of all tumors associated with transplanted patients. The most common site of Kaposi's sarcoma in immunosuppressed patients are extremities, but rare in head and neck area. A 42 years old woman who had systemic lupus erythematosus visited to our clinic because of gingival hyperplasia, and excisional biopsy revealed Kaposi's sarcoma. We experienced a case of favorable results using excision and chemotherapy, so we report with review of literatures.
RECURRENT CEMENTOBLASTOMA IN LEFT MANDIBLE : A CASE REPORT
Jung, Jun-Ho ; Kim, Yeo-Gab ; Lee, Baek-Soo ; Kwon, Yong-Dae ; Choi, Byung-Jun ; Kim, Young-Ran ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 349~352
Cementoblastoma is a benign ectomesenchymal odontogenic neoplasm that forms a mass of cementum or cementum-like tissue continuous with the tooth root. Cementoblastoma represents 1% to 6.2% of all odontogenic tumors, and occurs more than 75% arise in the mandible, with most cases arising in the molar and premolar regions. About 75% arises before the age of 30. Radiographically, it appears as a radiopaque mass with a thin radiolucent rim attached to the roots of a tooth. The recurrence rate is 37% in the current study and cortical expansion and perforation of the cortex are common findings in lesions that subsequently recurred. It is apparent that recurrence rate depends largely on the completeness of removal than any other factor. Here we present a 20 year old, female case of an unusual multiple recurrent cementoblastoma around a previous lesion which had been surgically excised 2 years ago.
REPAIR OF BILATERAL CLEFT LIP AND NOSE: PRINCIPLES AND METHODS OF MULLIKEN
Jung, Young-Soo ; Mulliken, John B. ; Sullivan, Stephen R. ; Padwa, Bonnie L. ;
Maxillofacial Plastic and Reconstructive Surgery, volume 31, issue 4, 2009, Pages 353~360
The principles for repair of bilateral cleft lip and nasal deformity are 1) symmetry, 2) primary muscular continuity, 3) proper philtral size and shape, 4) formation of the median tubercle and vermilion-cutaneous ridge from lateral labial elements, and 5) primary positioning of the alar cartilages to construct the nasal tip and columella. The authors underscore the essential role of preoperative premaxillary positioning for the synchronous closure of the cleft lip and primary palate, and describe Mulliken's operative technique. We discuss three-dimensional adjustments based on predicted fourth-dimensional changes. In a consecutive series of 50 patients, no revisions were necessary for philtral size or columellar length. Preoperative premaxillary positioning and primary repair of bilateral cleft lip and nasal deformity may impair maxillary growth. Nevertheless, a symmetric nasolabial appearance, rather than emphasis on maxillary growth, is the priority for the child with bilateral cleft lip.