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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Maxillofacial Plastic and Reconstructive Surgery
Journal Basic Information
Journal DOI :
Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
Editor in Chief :
Volume & Issues
Volume 33, Issue 6 - Nov 2011
Volume 33, Issue 5 - Sep 2011
Volume 33, Issue 4 - Jul 2011
Volume 33, Issue 3 - May 2011
Volume 33, Issue 2 - Mar 2011
Volume 33, Issue 1 - Jan 2011
Selecting the target year
Silk Fibroin and Substance P Combination Graft for the Reconstruction of a Bone Defect
Park, Ki-Yu ; Choi, Kyo-Hee ; Park, Young-Ju ; Song, Ji-Young ; Kim, Seong-Gon ; Jo, You-Young ; Kweon, Hae-Yong ; Kang, Seok-Woo ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 293~300
Purpose: Substance P is a well known neurotransmitter and has been known to mediate pain. Recently, it has been unveiled that substance P is involved in the recruitment of mesenchymal stem cells to wound sites. The purpose of this study was to exam bone formation when a combination of substance P and silk fibroin was used in a bone defect model. Methods: Twenty rabbits were used and 40 calvarial defects were formed. They were divided as 4 groups (unfilled control, silk only, silk+
/ml substance P; Sub10, and silk+
/ml substance P; Sub100). All animals were humanely sacrificed 4 or 8 weeks after grafting. The specimens were analyzed by micro-computerized tomography and histological analysis. Results: When compared to the unfilled control to silk only group, there was significant difference in bone mineral density (BMD) and the attenuation coefficient (AC) at 4 weeks (
=0.037 and 0.038, respectively). When compared Sub10 group to Sub100 group, there was significant difference in BMD and AC at 8 weeks (
=0.004 for all). Residual graft amounts were
% for silk only, Sub10, and Sub100 groups, respectively. When comparing the residual graft amount of silk only to sub10 or sub100, the differences were statistically significant (
<0.001). Conclusion: The silk fibroin scaffold showed higher BMD and AC than the unfilled control. The combination graft with substance P and silk fibroin scaffold showed a faster graft degradation than with a silk fibroin scaffold only.
Response of Odontoblast to the Bio-Calcium Phosphate Cement
Kim, Jin-Woo ; Kim, Sung-Won ; Kim, Gyoo-Cheon ; Kim, Yong-Deok ; Kim, Cheol-Hun ; Kim, Bok-Joo ; Kim, Uk-Kyu ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 301~307
Purpose: If the tooth structure is damaged, then it is impossible to regenerate the tooth. The materials used to restore the tooth structure are not related to the composition of the tooth. The materials used to restore the structure can't replace the natural tooth because they just fill the defective structure. Calcium phosphate cement remineralizes the dentin and almost replaces the natural tooth, but there are some disadvantages. We conducted basic tests with Biomimetic CPC (Bio-CPC) to make sure of the possibility of the biomaterial to remineralize the defective tooth structure. Methods: In this study, the bioactivity and biocompatibility of Bio-CPC were evaluated for its potential value as the bio-material for regeneration of damaged tooth structure by conducting a cell toxicity assay (WST-1 assay), a cytokinesis-block micronucleus assay, a chromosomal aberration test, total RNA extraction and RT-PCR on MDPC-23 mouse odontoblast-like cells. Results: The in vitro cytotoxicity test showed that the Bio-CPC was fairly cytocompatible for the MDPC-23 mouse odontoblast-like cells. Conclusion: Bio-CPC has a possibility to be a new biomaterial and further study of Bio-CPC is needed.
Alterations of Gene Expression by Beta-tricalcium Phosphate in Osteoblast-like MG63 Cells
Jeon, Jae-Yun ; Im, Tae-Yun ; Jeon, Seung-Hwan ; Hwang, Kyung-Gyun ; Park, Chang-Joo ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 308~313
Purpose: Beta-tricalcium phosphate (
-TCP) is a synthetic calcium phosphate ceramic that has widely been used as a bone material to repair bone defects. Despite many clinical studies, the molecular mechanism whereby this biomaterial alters the gene expression in osteoblasts to promote bone formation is poorly understood. Thus, we attempted to address this question by using microarray techniques to identify the genes that are differentially regulated in osteoblasts exposed to
-TCP. Methods: By using DNA microarrays, we identified several genes whose expression levels were significantly up- or down-regulated in osteoblast-likeMG-63cells cultured with
-TCP at a concentration of 100 mg/10 ml for 24 hours. Results: The differentially expressed genes covered a broad range of functional activities: signal transduction, transcription, cell cycle regulation, vesicular transport, apoptosis, immunity, cytoskeletal elements and cell proliferation and differentiation. Conclusion: The gene expression changes related to cell proliferation and differentiation, vesicle transport, immunity and defense could affect the osteogenic activities of osteoblasts for bone regeneration. However, further studies will be required to verify the relative importance of these genes in bone formation, their temporal and spatial expression patterns and their interactions with each other.
Evaluation of an Alveolar Bone Graft for Cleft Patients
Noh, Lyang-Seok ; Kim, Jong-Bae ; Chin, Byung-Rho ; Kwon, Tae-Geon ; Lee, Sang-Han ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 314~318
Purpose: The purpose of this study is to evaluate the results of alveolar bone grafting in patients with various types of cleft lip and to compare the success rates according to the lateral incisors and canines. Methods: The postoperative radiographs of 20 patient with a cleft lip and alveolar process alone (CLAP), complete unilateral cleft lip and palate (UCLP) and complete bilateral cleft lip and palate (BCLP) were retrospectively analyzed. The alveolar bone height was classified according to
byholm (1981) and Bergland (1986) and we evaluated the dentition at the time of surgery and the existence of a lateral incisor and impacted canines. Results: 16 (80%) of the 20 patients were assigned to Type I & II and they were considered successful. In the UCLP group, the success rate was significantly better than that of the UCLP and BCLP groups. The success rate was significantly better than when the cleft was grafted with the existence of a lateral incisor and before the eruption of the canines. Conclusion: The severity of the deformity influenced the success rate. The timing of the operation was a critical variable that affected the outcome in patients with cleft lip and palate.
Evaluation of Relapse according to Set-back Degree of the Mandible at Bilateral Sagittal Split Ramus Osteotomy in Mandibular Prognathism Patients
Yoo, Kyung-Hwan ; Kim, Su-Gwan ; Moon, Seong-Yong ; Oh, Ji-Su ; Kim, Saeng-Gon ; Park, Jin-Ju ; Jung, Jong-Won ; Yoon, Dae-Woong ; Yang, Seong-Su ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 319~322
Purpose: The purpose of this study was to examine the appropriate degree of set-back of the mandible by evaluating the rate of relapse after surgery. Methods: Among the patients who visited our hospital from January 2002 to January 2007 and who underwent orthognathic surgery, of the patients available for follow-up observation, the rate of relapse after surgery was investigated according to the set-back degree. The patients were divided into groups by the degree of set-back, and relapse was evaluated by the radiographs performed the day after surgery, 6 months after surgery, 1 year after surgery, 2 years after surgery and 3 years after surgery. Results: In cases that exceeded the limit of posterior movement of the mandible (13 mm) or that had the wrong position of the condyle, a greater tendency toward relapse was shown. Conclusion: Based on the results of this study, among the cases that required a large amount of posterior movement of the mandible, two jaw surgeries accompanied by bilateral sagittal split ramus osteotomy (BSSRO) and LeFort I osteotomy are recommended.
Prediction of Amount of Mandibular Set Back with 3 Plain Radiographs in Mandibular Sagittal Split Ramus Osteotomy
Noh, Lyang-Seok ; Kim, Jin-Wook ; Kwon, Tae-Geon ; Lee, Sang-Han ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 323~330
Purpose: The present study examined the reproducibility of an operation plan by comparing the jaw position of STO with the postoperative mandibular set back measurement in sagittal split ramus osteotomy. Methods: Thirty patients with class III dental and skeletal malocclusion and who were treated with BSSRO were reviewed. Three plain radiographs such as the panoramic view, the lateral cephalogram and the submentovertex view were taken before and after operation. Also, paper surgery for STO and model surgery were used to evaluate the amount of mandibular set back. Results: On the panoramic view, the amount of mandibular set back in STO was similar to the postoperative results of model surgery, but the amount of mandibular set back on the lateral cephalogram was smaller than the postoperative result of model surgery and then the amount of set back on submentovertex view was similar to the postoperative result of model surgery. Conclusion: Precise tracing and paper surgery should be performed for a combined expected STO in order to predict the exact amount of preoperative mandibular set back.
Comparative Analysis of the Reference Lines on McNamara's and Delaire's Analyses for the Anterior and Posterior Facial Relationship of Maxillofacial Deformity
Chung, Seung-Won ; Kim, So-Mi ; Byun, Sung-Soo ; Park, Hyung-Sik ; Jung, Young-Soo ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 331~336
Purpose: McNamara and Delaire analyses are two commonly used analytic methods, yet, they differ in their theoretic concepts and different reference lines are used for ideal surgical prediction. Therefore, the use of different analytic methods may result in different surgical plans. The purpose of this study was to compare the anterior and posterior relationship of the maxilla and mandible by using McNamara and Delaire analysis. Methods: 30 Korean patients (15 male and 15 female) who had visited the Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, for dentofacial evaluation were studied by using McNamara's and Delaire's analyses. Results: On the maxillary analysis, 26 out of 30 patients (86.7%) were in accordance. On the mandibular analysis, 20 out of 30 patients (66.7%) were in accordance. On the maxillary analysis, McNamara's analysis showed an average of 0.36 mm greater amount of prognathism compared to Delaire's analysis, and this was not statistically significant. On the mandibular analysis, McNamara's analysis showed an average of 6.03 mm greater amount of prognathism compared to Delaire's analysis, and this was statistically significant. On the mandibular analysis, 26 out of 30 patients (86.7%) showed a greater amount of prognathism on McNamara's analysis compared to that of Delaire's analysis. The remaining 4 patients (13.3%) showed the same amount of prognathism on both analyses. Conclusion: These results may serve as a reference for surgeons when determining which analytic method is to be used for optimal surgical results.
3-D CT Image Study of Effect of Glenoid Fossa on Menton Deviation
Cho, Jin-Hyoung ; Lee, Kyung-Min ; Park, Hong-Ju ; Hwang, Hyeon-Shik ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 337~345
Purpose: The purpose of this study was to define the relation of the degree of menton deviation and 3-D CT (computerized tomography) measurements of the glenoid fossa and the mandible, which are considered to have an influence on menton deviation. Methods: The CT images were obtained in 60 adults and these were transmitted to a computer and reconstructed using computer software. According to the degree of the menton deviation, which was measured on the posteroanterior cephalogram, the subjects were divided into the menton deviated group (30 adults) and the symmetry group (30 adults). A total of 11 measurements that might have an effect on menton deviation were determined and these were measured in the right and left sides using the function of 3-D measurement in the computer program. The 11 measurements consist of 6 measurements in the glenoid fossa (vertical position of the glenoid fossa and articular eminence, the sagittal position of the glenoid fossa and articular eminence, the depth of the glenoid fossa, and the anterior angle of the glenoid fossa), and 5 measurements in the mandible (ramus length, frontal ramal inclination, lateral ramal inclination, body length, body height). Results: The comparison of the differences between the menton deviated and symmetry groups and correlation analysis on the degree of menton deviation were carried out. The results of comparison of the right and the left difference between the menton deviated and symmetry groups showed that the vertical position and depth of the glenoid fossa were significantly increased in the menton deviated group. Conclusion: The results of the present study show that consideration of the shape and position of the glenoid fossa is necessary for making the diagnosis and administering proper treatment in facial asymmetry patients and especially growing patients.
Validity of Horizontal Reference Planes on Cone-Beam Computed Tomography Generated Postero-Anterior Cephalogram
Kang, Hee-Jea ; Kim, Jong-Ryoul ; Kim, Yong-Il ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 346~351
Purpose: The purpose of this study was to measure the angular differences between the horizontal reference planes on the CBCT generated PA cephalogram and the modified interpupillary plane, which was usually used in the clinical examination, and to evaluate the validity of the horizontal reference planes. Methods: The CBCT generated PA cephalogram was used to measure the angles between the FH, Lo and IP planes. The subjects consisted of 42 patients with facial asymmetry (males: 21, females: 21, mean-age: 21.6 years). The control groups were also assessed (males: 10, females: 10, mean-age: 23.8 years). The distance of the interpupil was measured on the soft-tissue volume rendered image. The angular differences were statistically analyzed using the
for inter-group comparisons and the
for intra-group comparisions. Results: The angle between the FH plane and IP plane (the angle of the FH-IP line) showed a statistically significant difference between the two groups (
<0.05). There was no statistical differences between each angle (angle of the FH-IP line, angle of the FH-Lo line, angle of the Lo-IP line) on the intra-group comparision (
>0.05). Conclusion: The angle between the Lo line and IP line (angle of the Lo-IP line) showed no statistically significant difference in both the control and asymmetry groups. Therefore, the Lo line could be used as a horizontal reference plane in CBCT generated PA cephalograms.
Retrospective Study of Sandblasted, Large-grit and Acid-etched Implant
Jo, Ji-Ho ; Kim, Su-Gwan ; Moon, Seong-Yong ; Oh, Ji-Su ; Park, Jin-Ju ; Jung, Jong-Won ; Yoon, Dae-Woong ; Yang, Seong-Su ; Jeong, Mi-Ae ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 352~358
Purpose: This study evaluated the prognosis and survival rate of SLA (Sandblasted, Large-grit and Acid-etched) implants and it also evaluated the prosthodontic complications and the associated factors. Methods: Twenty seven patients (14 men and 13 women, mean age: 54.9) who visited Chosun University Hospital Implant Center with the chief desire for placement of an implant in an edentulous area from March, 2008 to December 2008 and who received placement of a SLA implant (
, Dentium Co., Korea) were selected for this study. Results: The average follow-up period was 15 months and the study was based on the treatment records, radiographs and clinical examinations. A total of 69 implant cases were retrospectively assessed for the width and length of the implant, the primary and secondary stability, the combined surgery, the employed bone graft material and barrier membrane, the status of the opposing tooth, implant failure and the prosthetic complications. During the follow-up period (average: 15 months), the accumulative survival rate of the 69 implants in 27 patients was 100%. Complications such as infection, sinusitis and fixture exposure after surgery were seen for 5 implants in 4 patients. Complications such as screw loosening, contact loosening and peri-implant gingivitis after prosthodontic treatment occurred in 7 cases (10.14%). Conclusion: This study reports placement of SLA implants may cause various complications, yet the final accumulative survival rate was 100%. The SLA implant (
) has an excellent clinical survival rate and outcome.
Guided Bone Regeneration Using Mineralized Bone Allograft and Barrier Membrane Derived from Ox Pericardium
Lim, Hyoung-Sup ; Kim, Su-Gwan ; Moon, Seong-Yong ; Oh, Ji-Su ; Jeong, Kyung-In ; Park, Jin-Ju ; Jeong, Mi-Ae ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 359~362
Purpose: This study evaluated the clinical applications of implant placement and guided bone regeneration using a mineralized bone allograft and a barrier membrane derived from ox pericardium Methods: From January 2007 to June 2009, among the patients who received an implant at Chosun University Dental Hospital, patients were selected if they were treated with guided bone regeneration (GBR) with simultaneous implant placement or GBR prior to implant placement. The selected patients were sorted according to the materials and membranes used in GBR, and the implant survival rate was recorded by clinical examination and reviewing the medical records and the radiographs. Each study list was analyzed by SPSS (version 12.0, SPSS Inc., USA) software and the survival rate was verified by Chi-square tests.
values less than 0.05% were deemed significant. Results: 278 implants were placed on a total of 101 patients and 8 implants resulted in failure. Three implants failed among 15 implants with only a mineralized bone allograft. No failure was shown among the 74 implants placed with mineralized bone allograft and a barrier membrane derived from ox pericardium. One group of 4 implant placements showed failure among the 102 implants placed with a mineralized bone allograft and another bone graft material. The group that had a barrier membrane derived from ox pericardium with a mineralized bone allograft or other bone materials showed no implant failure. Three failures were shown among the 21 implants placed with only bone graft and not using a membrane. The group with membranes other than a barrier membrane derived from ox pericardium showed 5 failures among 170 implants. Conclusion: The implant survival rate of the group with GBR using a mineralized bone allograft was 96.3%, which meant there was little difference compared to the groups of another bone graft materials (98.9%). The implant survival rate of the group without a membrane-was 85.7% and it showed a significant difference compared to the group using a barrier membrane derived from ox pericardium (100%) and the group using another membrane (97.1%).
The Correction of the Mandibular Defect Using Porous Polyethylene: Case Report
Im, Jae-Hyung ; Kim, Su-Gwan ; Moon, Seong-Yong ; Oh, Ji-Su ; Park, Jin-Ju ; Jeong, Mi-Ae ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 363~367
Genioplasy with osteotomy is a flexible and useful procedure. However, osteotomy can cause different types of morbidity. Chin augmentation with porous polyethylene (
) has become popular in the recent years. Porous polyethylene (
) is an excellent biomaterial for reconstructing facial deformities.
has a porous architecture, which prevents capsule formation and decreases the degree of foreign-body reaction. In addition, it can be easily cut with scissors and molded, and it also maintains its shape. We report here on a satisfactory case of chin augmentation with using porous polyethylene (
Progressive Transformation of Germinal Centers in Submandibular Area: Case Report
Park, Su-Won ; Jang, Soo-Mi ; Kim, Dong-Yul ; Son, Jang-Ho ; Cho, Yeong-Cheol ; Sung, Iel-Yong ;
Maxillofacial Plastic and Reconstructive Surgery, volume 33, issue 4, 2011, Pages 368~372
Progressive transformation of germinal centers (PTGC) is mostly a disease of young adults and it presents as unexplained, asymptomatic, localized or generalized lymphadenopathy that is usually persistent or recurrent over a period of many years. PTGCs are larger than regular germinal centers and they contain a variable proportion of small mantle zone lymphocytes and so they become progressively transformed and they may result in the loss of clear demarcation between them and the mantle zone. PTGC may resemble the nodules of nodular lymphocyte predominant Hodgkin's disease (NLPHD) and it may be mistaken for NLPHD. Histological and immunohistochemical studies are helpful in differentiating these diseases. Because of the relatively frequent recurrences of PTGC, follow-up and repeat biopsy are indicated. Although PTGC is not considered to be a premalignant condition, PTGC may occur prior to, concurrent with or following NLPHD. This emphasizes the need for ongoing follow-up and repeat biopsy. Although PTGC is reported in 3.5% to 10% of the cases of chronic nonspecific lymphadenopathy, oral & maxillofacial surgeons are not widely aware of this condition and its clinical implications. Herein, we present a case of PTGC. A 24-year-old male without any history of immunodeficiency or autoimmune disease was admitted to the Department of Oral & Maxillofacial surgery at Ulsan University Hospital for evaluation of a right submandibular swelling. He had another mass on the right thigh that was noticed about 1 year ago. The submandibular lesion was completely resected and biopsied. The histological findings and immunohistochemical stains (CD3, CD15, CD20, CD30, CD57, BCL-2, EMA) were consistent with PTGC. He was followed up without any other complaints for 9 months.