Go to the main menu
Skip to content
Go to bottom
REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Biomedical Engineering Research
Journal Basic Information
Journal DOI :
The Korea Society of Medical and Biological Engineering
Editor in Chief :
Volume & Issues
Volume 10, Issue 3 - Dec 1989
Volume 10, Issue 2 - Sep 1989
Volume 10, Issue 1 - Jun 1989
Selecting the target year
우리나라 의용생체공학의 현황과 전망
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 83~88
This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively.
우리 학회 활성화 방안
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 89~90
To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased.
의공산업의 현황과 전망
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 91~93
We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate.
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 94~96
Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained.
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 97~101
N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms.
혈액정화장치의 현황과 문제점
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 102~105
In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research.
의료영상진단기의 현황과 전망
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 106~108
A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells.
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 109~111
An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients.
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 112~113
Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult.
체외충격파를 이용한 결석의 치료
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 114~116
A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator.
의료용재료의 최근 개발현황
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 117~124
The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan`s method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements.
Functional Exploration of Optokinetic System by a Full Visual Field Stimulation
Kim Nam Gyun ; KOPP C. ;
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 125~130
In the present study, we described a test to explore the function of optokinetic system which subjected to a full visual field stimulation using two different stimulus images patterns. Our results were interesting in a point of view that the stimulation image pattern had non- neglisible influence on the optokinetic response and that in a bidimensionnel image such as the randomly distributed spots images pattern the linearity of system was assured upto the stimulus velocity of about 50 deg/sec for normal subject. As for measuring human optokinetic after nystagmus, the regular stripes pattern was rather desirable than the randomly distributed spots pattern in this study.
The Feacture Extraction of Background EEG in the Time Domain by LS Prony Method.
Ju, Dae-Seong ; Hwang, Su-Yong ; Choe, Gap-Seok ;
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 131~138
In this paper the feature of background EEG is extracted by LS Prony Method for the analysis of background EEG in the time domain. Autocorrelation leg estimates are not required with the LS Prony method. The Prony method is required any the solution of two serfs of simultaneous linear equation and a polynominal rooting. That the optimal order of this model is the 6-th order is determined by using Akaike' s Information Criterial test. From the experimential results the alpha band amplitude is the largest among alpha band beta band theta band delta band and beta band amplitude is larger than that of the delta band and theta band. The sustained time for the alph a band, the beta band, the delta band and the theta band is 2, 3461 (sec), 0.6490(sec), 0.3120(sec), 0.7046(sec) respectively. Consequenty the alpha band is maintained in the whole subjects, the beta band, the delta band, the theta band are existed intermittently in each subjects.
Design and Analysis of A New Type of the Motor-Driven Blood Pump for Artificial Heart
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 139~150
A new motor-driven blood pump for artificial heart was developed. In this blood pump, a small size, high torque brushless DC motor was used as an energy converter and the motor rolls back and forth on a circular track. This movement of the "rolling-cyliner" causes blood ejection by alternately pushing left or right polyurethane blood sacs. This moving-actuator mechanism could be eliminate two potential problems of other motor-driven artificial hearts such as large size and poor anastomosis for the implantation. Theoretical analyses on the pump efficiency, the temperature rise, and the inflow mechanism were also performed. In a series of mock circulation tests, the theoretical analyses were compared to the measured hemodynamic and mechanical values. The pump system was shown to have sufficient cardiac output (upto 9 L/min), sensitivity to preload, and mechanical stability to be tested as an implantable total artificial heart.ial heart.
Design of Lung Sound Analyzer Using Adaptive Digital Filter and DSP Chip
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 151~156
Lung sound analyer which can provide an objective diagnosis of patients with pulmonary and bronchial disorders is designed. For the purpose of power spectrum analysis, adaptive digital filtering technique and TM - S320C25 DSP chip is used. As a results, adaptive lattice Wiener filter could eliminate heart sounds with a few of 10th order and on the distribution of power spectrum each patterns has shown in normal vescicular breathy from 100 Hz to 200 Hz, in crackle sound from 100 Hz to 400 Hz, in wheeze sound from 150 Hz to 600 Hz.
Arbitrary Cross Sectional Display from Three-dimensional Reconstructed Image by Hierarchical Model
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 157~164
Three-dimensional imaging and manipulation of CT data are becoming increasingly important for deterRing the complex structure and pathologies. Octree which is a hierarchical data model is used to reconstruct three- dimensional objects from CT scans. Orthogonal cross sections are displayed by traverse the octree partially. Arbitrary oblique planes are derived by intersecting the square region of plane and cubic volume of octal node. Thia method enables the display of multi-structured complex organ ann the realization by personal computer.
A Study on the Estimation of Temperature Dependance in Tissue by Ultrasound
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 165~172
In this paper, the temperature dependence of tissue is estimated by measuring the attenuation coefficient and the propagation velocity of ultrasonic reflection signal. And, on the basis of expeiments, the possibility of non- invasive temperature estimation is considered. Specimens in the experiment are acryl 1)late. muscle, fat and liver of pig. The temperature of specimen is controlled by water bath which is able to adjust temperature a quarter of a degree. Through the series of experiments, we conformed that the ultrasonic parameters have lin earity to a certain extents with the change of tissue's temperature. And we expect that noninvasive temperature estimation of tissue can be realized after several preconditions be satisfied with the standard experiment conditions and a great number of base data.
Medical Image Data Compression Using a Variable Block Size Vector Quantization
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 173~178
A vector quantization technique using a variable block size was applied to image compression of digitized X -ray films. Whether the size of VQ block should be subdivided or not is determined experimentally by the threshold value. The simulation result shows that the performance of the proposed vector quantizer is suitable for the medical image coding, which is applicable to PACS( Picture Archiving and Communication System).
Development of a Multipurpose Cure-appliance Using Microwave
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 179~184
There are microwave hyperthermia, microwave surgical knife, and microwave tissue coagulator etc. as the cure-appliance using microwave. The object of this paper is to develope the multipurpose cure-appliance which has the functions that can be used intestinal tumor as well as the existing superficial tumor. And this also have the function of surgical knife and tissue coagulator with endoscope. And then ascertain its functions through the experiments, and to suggest the direction for reserch hereafter.
Discriminant Analysis of Parameter for Cardiac Arrythmia Detection
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 185~190
In this paper, the discriminant analysis was performed on parameter for detection of cardiac arrythmia. The parameters used for discriminant analysis was two group. One group consist of 05 width and Heart rate, and the other Morphology and Heart Rate. For this study, we designed data acquisition system for EKG signals. The parameters pre-processed by this system was heart rate, 05 width and Morphology. And then, we analyzed the discriminancy of two group and extracted the quantity of discriminancy. The analysis results showed first that the group with morphology and heart rate is better discriminant than with 05 width and heart rate : next, that it can quantify the discriminany of each group of diseases.
Controlled Release of 5-Fluorouracil from Crosslinked Poly(2-hydroxyethyl methacrylate)
Cho, Chong-Su ; Chung, Sook-Ja ; Lee, Kang-Choon ;
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 191~194
A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network.
Polymer Surfaces for Cell Adhesion II. Cell Culture on Surface-modified Polymers
Journal of Biomedical Engineering Research, volume 10, issue 2, 1989, Pages 195~202
Chinese Hamster Ovary( CHO) cells were cultured on the surface-modified polymers described in the previous study( "Polymer Surfaces for Cell Adhesion. 1. Surface Modification of Polymers and ESCA Analysis, " J. of KOSOMBE, Vol. 10, No. 1, 43-51, 1989). Among the physicochemical treatment methods. the chloric acid treatment was found to be the best method of rendering the polymer surfaces adhesive for CHO cells probably due to the high density of hydroxyl groups on the surface. Among the biological methods, the fibronectin treatment was best for CHO cell-compatibility probably due to specific active sites existed on the tell-binding domains of the fibronectin structure. When we compare the cell-compatibility of the chloric acid - and the fibronectin -treated PET surfaces, the number of cells attached on the surfaces were increased by 460.5 % and 559.0 % and, respectively, after 32 hr CHO cell culture, compared to that of untreated PET.eated PET.