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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of Biomedical Engineering Research
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Journal DOI :
The Korea Society of Medical and Biological Engineering
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Volume & Issues
Volume 14, Issue 4 - Dec 1993
Volume 14, Issue 3 - Sep 1993
Volume 14, Issue 2 - Jun 1993
Volume 14, Issue 1 - Mar 1993
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A Study on Estimation of Formants and Articulatory Motion Trajectories using RLSL Adaptive Linear Prediction Filter
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 1~8
In this study, the extractions of formants and articulatory motion trajectories for Korean complex vowels are performed by using the RLSL adaptive linear prediction filter. This enables us to extract accurate spectrum in transition of speech signal. This study shows that the RLSL algorithm is superior to the Levinson algorithm, specially in transition part of speech.
A Study on the Improvement of Compression Method Using Hilbert Curve Scanning for the Medical Images
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 9~16
For efficient storage and transmission of medical images, the requirement of image com pression is increasing. Because differences between reconstructed images and original images are related with errors In the diagnosis, lossless compression is generally preferred in mod- ical images. in Run Length Coding which is one of the lossless compression method, we have applied modified scanning direction based on the Hilbert curve, which is a kind of space fill ins curve. We have substituted the traditional raster scanning by Hilbert curve direction scanning. Using this method, we have studied enhancement of compression efficiency for medical images.
Temperature Rise During Laser Photodynamic Therapy in a Mouse Tumor Model
Yoon, Gil-Won ;
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 17~22
Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided intro two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weights). The other group received no Photofrin E Mice from both groups were irradiated for approximately 15 minutes at 100,300, or
with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photofrin II increased surface temperature by at least 40% and the temperature rise due to
irradiation exceeded values for hyperthermia. Lights and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise.
동서양인의 대퇴골 비교연구
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 23~30
We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs and others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized nomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh loci computer. The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal (tare Index are greater by the amount of approximately 8" and 0.5, respectively, (2) the shape of the isthmus cross section is more round , and (3) the distance between the lesser trochanter and the proximal border of the isthmus is shorter by about 15 mm. The results suggested that the femoral component suitable for Asians should be dif- ferent (rom the currently-used components designed and manufactured mostly by European or American companies.
Measurement of Nonlinear Propagation Characteristics of Vibration in the Tissue Using Bispectral Analysis
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 31~40
It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propa gation characteristics of the internal vibration in the tissue for the low frequency mechanical vibra lion by using bispectral analysis is proposed. In the method, low frequency vibration of
is applied on the surface of the object, and the waveform of the internal vibration
is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal
at the frequencies (
) and (
) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, where since bispectrum is free from the gallssian additive noise we can get the value with high S/N. Basic experimental system is con structed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization.
The Preload-Responsive Regulation of Cardiac Output in Total Artificial Heart Using Dual Adaptive Controller
Lee, Sang-Hun ; Kim, In-Yeong ; An, Hyeok ; Min, Byeong-Gu ;
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 41~50
This paper proposes an adaptive technique for the cardiac output regulation of a pendulum type electromechanical TAH. This techinque, which consists of two RLSE's and two PASTC' 5, performs Its controllability over the TAIB so that the m(RAP) and m(LAP) values re- main close to their desired values under she assumption that the variation of m(RAP) and m (LAP) are dominated by the variation of C.0. and the difference between the left and right ventricular output, respectively. To evaluate the performance of the proposed control system, a simulation is performed by using a human model which contains physiologic, drug and treatment, artificial heart and noise models. As a result, dual adaptive controller showed that abnormal m(LAP) and m(RAP) could be recovered to the normal range within 10minute and maintained desired value in steady state. The operation of this controller prored to be robust in spite of the rapid variation of human status.
Preparation of Living Skin Equivalent by using the Contracted Collagen Lattice and Cultured Human Keratinocytes
Park, Jae-Gyeong ; Jo, Geum-Cheol ; Park, Ho-Cheol ;
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 51~62
An experimental study was performed for the preparation of living skin-equivalent by the using collagen gel contraction with human fibroblasts as neodermls and cultured human keratinocytes as neoderm is . The results were as follows ; 1) The rate of collagen gel contraction was dependent on the number of fibroblasts into the lattice and collagen contraction was progressed according to the increment of the number of the cells. 2) The rate of collagen gel contraction was progressed according to the decrement of the contraction of the collagen. 3) The rate of gel contraction was progressed according to the increment of serum concentration in the fixed concentration of the fibroblasts and collagen. 4) The lattice contraction was decreased according to the increment of the population doublings of the fibroblasts. 5) Macroscopically, the artificial dermis was gray white in color and tissue-like consistency and elas- ticity. 6) Microscopically, three dimensionally contracted artificial dermis showed more dense fibroblasts and its newly formed collagen fibrils in the matrix than one dimensionally contracted one. 7) Finally prepared skin-equivalent showed good attachment of living stratified keratinocytes to the dermal equivalent microscopically. It has been proposed that newly formed skin-equivalent is suitable for the graft of extensively and deeply burned patients. Shortening of the manufacturing period of skin-equivalent and development of conservation technique as a readily usable state are to be solved for our ongoing works.
The Effect of Background Grey Levels on the Visual Perception of Displayed Image on CRT Monitor
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 63~72
In this paper, the effect of background grey levels on the visual perception of target image displayed on CRT monitor has been investigated. The purpose of this study is to investigate the efficacy of CRT monitor as a display medium of image Information especially in medical imaging field. Tllree sets of experiments have been performed in this study : the first was to measure the luminance response of CRT monitor and to find the best fitting equation, and the second was the psychophysical experiment measuring the threshold grey level differences between the target image and the background required for visual discrimination (or various background grey levels, and the third was to develop a visual model that is predictable of the threshold grey level difference measured in the psychophysical experiment. The result of psycophysical experiment shows that the visual perception performance is significantly degraded in the range of grey levels lower than 50, which is turned out due to she low luminance change of CRT monitor in this range while human eye has been adapted lo relatively bright ambient illumination. And it Is also shown in the simulation study using the developed visual model that the dominant factor degrading the visual performance is the reflected light from the monitor surface by ambient light in general illumination condition.
Implementation of Radial Pulse Diagnosis System using Inyoung-Cheongu Comparison Method
Lee, Ho-Jae ; Park, Yeong-Bae ; Heo, Ung ;
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 73~80
This paper describes the implementation of a computerized radial pulse diagnosis by Elds of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diag nosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed It. Then, we have got the characteristic parameters of radial pulse wave and also quantified thats according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial Pulse diagnosis system and then we confirmed the PossibiliLy for realization of automatic radial Pulse diagnosis in korean traditional medicine.
The Effects of Physiological Heating and Exercise on the Optical Properties of Biological Tissue.
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 81~88
This paper is the study of the reflectance of light from biological tissue for red and Infrared wavelengths and relates the acquired reflectance data to expected physiological changes within the skin and muscle layers associated with heat and exercise. The instrument was disigned to collect data from the calf muscle in human subjects with probe located at the surface of skin. Rapid data acquisition method allowed monitoring of rapid changes in reflecttance due to a stimulus. This study demonstrates that changes in O2 saturation and blood fractional volume expected within the dermis and muscle layers were asserted by examining the slopes of the plotted index for heat and exercise. The results presented in thls study support the claim that reflectance can separately discriminate between changes of blood volume and oxygenation in muscle and in skin. The data demonstrate the ability to measure consistent changes In tissue optical properties during exercise and heat.
Increase In Mean Alveolar Pressure Due To Asymmetric Airway Geometry During High Frequency Ventilation
Cha, Eun-J. ; Lee, Tae-S. ; Goo, Yong-S. ; Song, Young-J. ;
Journal of Biomedical Engineering Research, volume 14, issue 1, 1993, Pages 89~96
During high frequency ventilation (HFV), mean alveolar pressure has been measured to increase with mean airway opening pressure controlled at a constant level in both humans and experimental animals. Since this phenomenon could potentiate barotrauma limiting advantages of HFV, the present study theoretically predicted the difference between menu alveolar and airway opening pressures (
). In a Weibel's trumpet airway model, approximated formula for
was derived based on momentum conservation assuming a uniform velocity profile. The prediction, equation was a func pion of gas density(
), mean flow rate(Q), and diameter of the airway opening where the pressure measurement was made(
. This was a result of the difference in crosssectional area between the alveoli and the airway opening. A simple aireway model experiment was performed and the results well fitted to the prediction, which demonstrated the validity of the present analysis. Previously reported
data from anesthetized dogs in supine position were comparable to the predicted values, indicating that the observed dissociation between mean alveolar and airway opening pressures during HFV can be explained by this innate geometric (or cross-sectional area) asymmetry of the airways. In lateral position, however, the prediction substantially underestimated the measurements suggesting involvement of other important physiological mechanisms.