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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Biomedical Engineering Research
Journal Basic Information
Journal DOI :
The Korea Society of Medical and Biological Engineering
Editor in Chief :
Volume & Issues
Volume 24, Issue 6 - Dec 2003
Volume 24, Issue 5 - Oct 2003
Volume 24, Issue 4 - Aug 2003
Volume 24, Issue 3 - Jun 2003
Volume 24, Issue 2 - Apr 2003
Volume 24, Issue 1 - Feb 2003
Selecting the target year
A Study on the Stiffness Estimation in Soft Tissue Using Speckle Brightness Variance Tracking
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 141~149
This paper proposes a method of measuring and imaging the stiffness of human soft tissue to diagnose cancers or tumors which have been difficult to detect in ultrasound B-mode imaging systems. To measure the soft tissue stiffness, sinusoidal vibrations are applied to it, and the magnitude of its mechanical vibration is determined by estimating the temporal variation of speckle pattern brightness in ultrasound B-mode images. It is verified by simulation and experiment that the proposed method can estimate the relative tissue stiffness from B-mode images with a relatively small amount of computation.
Study on Nonlinearites of Short Term, Beat-to-beat Variability in Cardiovascular Signals
Han-Go Choi ;
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 151~158
Numerous studies of short-term, beat-to-beat variability in cardiovascular signals have used linear analysis techniques. However, no study has been done about the appropriateness of linear techniques or the comparison between linearities and nonlinearities in short-term, beat-to-beat variability. This paper aims to verify the appropriateness of linear techniques by investigating nonlinearities in short-term, beat-to-beat variability. We compared linear autoregressive moving average(ARMA) with nonlinear neural network(NN) models for predicting current instantaneous heart rate(HR) and mean arterial blood pressure(BP) from past HRs and BPs. To evaluate these models. we used HR and BP time series from the MIMIC database. Experimental results indicate that NN-based nonlinearities do not play a significant role and suggest that 10 technique provides adequate characterization of the system dynamics responsible for generating short-term, beat-to-beat variability.
Construction and Operation of a 37-channel Hemispherical Magnetoencephalogram System
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 159~165
We developed a 37-channel magnetoencephalogram (MEG) measurement system based on low-noise superconducting quantum interference device (SQUID) magnetometets, and operated the system to measure MEG signals. By using double relaxation oscillation SQUIDs with high flux-4o-voltage transfers, the SQUID outputs could be measured directly by room temperature preamplifiers and compact readout circuits were used for SQUID operation. The average field noise level of the magnetometers is about 3 fT/√Hz in the white region, low enough for MEG measurements when operated inside a magnetically shielded room. The 37 magnetometers were distributed on a hemispherical surface haying a radius of 125 mm. In addition to the 37 sensing channels. 11 reference channels were installed to pickup external noise and to form software gradiometers. A low-noise liquid helium dewar was fabricated with a liquid capacity of 30 L and boil-off rate of 4 L/d. The signal processing software consists of digital filtering, software gradiometer, isofield mapping and source localization. By using the developed system, we measured auditory-evoked fields and localized the current dipoles, demonstrating the effectiveness of the system.
Background Noise Reduction by Software Methods in the 37-channel SQUID Magnetometer System
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 167~173
Measuring subtle neuromagnetic signals requires eliminating background noises. Especially, a SQUID magnetometer is very sensitive to the magnetic noise even from a distant source. As typical software methods, we use the synthetic gradiometer of the adaptive filtering to reduce the noises. In this article, we present noise reduction effects in our 37-channel SQUID magnetometer system by applying each method including the frequency-domain adaptive filtering and discuss a selective application of the methods to the detection of clinical magnetoencephalogram signals.
The Study of Muscle Fatigue Index Searching in terms of Median Frequency Analysis of EMG Signals during Isotonic Exercise
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 175~181
Studies of muscle fatigue have mostly been checked under isometric exercise. However EMG signals from isotonic exercise generate uncontrollable noise, so there were difficulties in gathering reliable median frequency and muscle fatigue index if frequency analysis was equally applied in isometric exercise. This study tried to compare the differences of muscle fatigue determinant variables in terms of median frequency searching methods of EMG signal, which was estimated in isotonic exercise. To accomplish this, we determined median frequency by using different FFT intervals and overlapping ration of consecutive FFT sections under the same EMG signal, and then searched for a linear regression line, and compared initial median frequency, slope, and muscle fatigue index which were variables under the linear regression line. In result of comparison, initial median frequency was more elevated as FFT exercise interval became larger. The slope of the linear regression line showed distinguishable decreasing tendency as FFT intervals were larger and overlapping sections were smaller. Significant tendency of muscle fatigue index in FFT interval was shown by high muscle fatigue index in specific FFT intervals.
Implementation on the Urine Analysis System using Color Correction and Chromaticity Coordinates Transform Methods
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 183~192
A transformation methode of the chromaticity coordinates was proposed to calibrate the measured data obtained by a urine analysis system which implemented in our previous study. Generally. the reacted color of a reagent strip by urine analysis system often exhibit the color distortions due to nonlinear characteristics of the various devices that is the optic module mechanism. hardware, and surround circumstance. A color correction method for minimizing the color distortion play a few role in maintaining high accuracy and reproduction of the urine analysis system. In this work, we used the compensation method such as the shading correction, the characteristic curve extraction of RGB color by means of third order spline interpolation, and linear transformation using a reference color. In addition, 1931 CIE XYZ color space was used to compensate the color of the measured data by a standard reference system as colorimeter. A compensation matrix was obtained so that the output values of the urine analysis system is nearly equal to that of a standard reference system for identical color sample. Color correction obtained by a urine analysis system which implemented in our previous study exhibited a good color accuracy when it was compared with the reference data. Observed result from an experiments on ten items or a urinalysis strip that color difference or between two urine analysis system was 1.28.
A Study on the Design of Classifier for Urine Analysis System
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 193~201
In this paper, a classifier of urine analysis system was designed using preprocessing and fuzzy algorithm. Preprocessing were processed by normalizing data of strip using calibration curve composed of achromatic colors value and by calculating three stimulus. FUZZY classifier capable of analyzing a qualitative concentration of test items was composed of fuzzifier by gaussian shaped membership function, inference of MIN method, and defuzzifier of centroid method through verification by measuring standard solution and by classifying concentration classes. After tuning membership function according to relating standard solution with urinalysis sample, the possibility to adapt classifier designed for urine analysis system near a bed was verified as classifying measured urinalysis samples and observing classified result. Of all test items, experimental results showed a satisfactory agreement with test results of reference system.
Effect of Indium on the Microstructures and Mechanical Properties of Au-Pt-Cu Alloys
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 203~208
The effect of indium on the microstructure and hardness of a Au-Pt-Cu ternary alloy was investigated using optical microscopy, differential scanning calorimeter, scanning electron microscopy x-ray diffractometry, electron probe microanalizer and vickers hardness tester. A hardness of the solution floated Au-Pt-Cu-0.5In quarternary alloy with 0.5 wt.% was reached a maximum value (162 Hv) in 30 min at 550
in the range of 150 to 950
but that of the alloy was rapidly increased until 30 min with increasing aging time at 550
and after that was remained almost constant value. Also, the microhardness of the matrix Au-Pt-Cu ternary alloy aged at 550
for 30 min was continuously increased with indium contents and the grain size of Au-Pt-Cu ternary alloy decreased as increased indium contents. Analyses of EPMA and XRD revealed that the matrix Au-Pt-Cu-In quarternary alloy is composed of fcc structure and intermetallic InPt
precipitate with Ll
structure. Based on this investigation, it can be concluded that an increase in microhardness of Au-Pt-Cu-In quarternary alloy is due to precipitation hardening InPt
and grain size refinement.
Correlation Between Joint Angular Displacement and Moment in the Human Foot
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 209~215
The goal of this study was to investigate the relationship between kinematic and kinetic characteristics of foot joints resisting ground reaction force. Passive elastic joint moment and angular displacement were obtained from the experiment using 3 cameras and force plate. The relationship between joint angle and moment was mathematically modeled by using least square method. The ranges of motion of joints ranged from 5
except metatarsophalangeal joint. In the study, we presented simple mathematical models that could relate joint angle and plantar pressure. From this model, we can got the kinematic data of joints which is not available from conventional motion analysis. Furthermore, the model can be used not only for biomechanical model which simulates gait but also for clinical evaluation.
Multiple Transmit Focusing Method With Modified Orthogonal Golay Codes for Ultrasound Imaging
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 217~231
Coded excitation with complementary Golay sequences is an effective means to increase the SNR and penetration of ultrasound imaging. in which the two complementary binary codes are transmitted successively along each scan-line, reducing the imaging frame rate by half. This method suffers from low frame rate particularly when multiple transmit focusing is employed, since the frame rate will be further reduced in proportion to the number of focal zones. In this paper. a new ultrasound imaging technique based on simultaneous multiple transmit focusing using modified orthogonal Golay codes is proposed to improve lateral resolution with no accompanying decrease in the imaging frame rate, in which a pair of orthogonal Golay codes focused at two different focal depths are transmitted simultaneously. On receive, these modified orthogonal Golay codes are separately compressed into two short pulses and individually focused. These two focused beams are combined to form a frame of image with improved lateral resolution. The Golay codes were modified to improve the transmit power efficiency (TPE) for practical imaging. Computer simulations and experimental results show that the proposed method improves significantly the lateral resolution and penetration of ultrasound imaging compared with the conventional method.
Influence of Impact Angle on Deformation in Proximal Femur during Slide Falling
Journal of Biomedical Engineering Research, volume 24, issue 3, 2003, Pages 233~239
Falling related injuries are categorized as the most serious and common medical problems experienced by the elderly, hip joint fracture, one of the most serious consequences of falling in the elderly, occurs in only about 1% of falling. Nevertheless, hip fracture accounts for a considerable part of the disability, death, and medical costs associated with falling. In this study, we considered the impact angle and displacement rate in falling as another factor affecting femoral strength. Using a fresh-frozen human femur, we developed system to simulate the falling condition and then conducted the experiments changing the impact angle (0
) of proximal femur. Also, in order to analyze the relative risk due to falling to normal situation in proximal femur, we did the static test simulating the two-legged stance condition. The results showed that the change in impact angle affected the strain distribution in proximal femur, and that a large deformation in femoral neck than in other sites. Furthermore despite low impact velocity, a large deformation in proximal femur occurred in the impact test and different strain distribution was observed compare to the static case.