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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of Biomedical Engineering Research
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Journal DOI :
The Korea Society of Medical and Biological Engineering
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Volume & Issues
Volume 25, Issue 6 - Dec 2004
Volume 25, Issue 5 - Oct 2004
Volume 25, Issue 4 - Aug 2004
Volume 25, Issue 3 - Jun 2004
Volume 25, Issue 2 - Apr 2004
Volume 25, Issue 1 - Feb 2004
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Design and Performance Analysis of Current Source for 3.0T MREIT System
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 165~169
In Magnetic Resonance Electrical Impedance Tomography (MREIT), we inject current through electrodes placed on the surface of a subject and measure the induced magnetic flux density distribution using an MRI scanner. This requires a constant current source whose output pulses are synchronized with MR pulse sequences. In this paper, we present a design and performance analysis of a current source used in a 3.0T MREIT system. The developed current source was tested using a saline phantom. We found that its performance is satisfactory for the current MREIT system. We suggest future improvements for better SNR(signal-to-noise ratio).
A Biomechanical Study on the Various Factors of Vertebroplasty Using Image Analysis and Finite Element Analysis
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 171~182
This study investigates the biomechanical efficacies of vertebroplasty which is used to treat vertebral body fracture with bone cement augmentation for osteoporotic patients using image and finite element analysis. Simulated models were divided into two groups: (a) a vertebral body, (b) a functional spinal unit(FSU). For a vertebral body model, the maximum axial displacement was investigated under axial compression to evaluate the effect of structural integrity. The stiffness of each FE model simulated was normalized by the stiffness of intact model. In the case of FSU model, 3 types of compression fractures were formulated to assess the influence on spinal curvature changes. The FSU models were loaded under compressive pressure to calculate the change of spinal curvature. The results according to the various factors suggest that vertebroplasty has the biomechanical efficacy of the increment of structural reinforcement in a patient who has relatively high level of BMD and a patient with the amount of 15％, PMMA injection of the cancellous bone volume. The spinal curvatures after compression fracture simulation vary from 9
of kyphosis compared to that the spinal curvature of normal model was -2.8
of lordosis. These spinal curvature changes cause the severe spinal deformity under the same loading. As the degree of compressive fracture increases the spinal deformity also increases. The results indicate that vertebroplasty has the increasing effect of the structural integrity regardless of the amount of PMMA or BMD and the restoration of decreased vertebral body height may be an important factor when the compressive fracture caused the significant height loss of vertebral body.
Magnetic Resonance Imaging of a Current Density Component
Oh, Suk-Hoon ; Park, Tae-Seok ; Han, Jae-Yong ; Lee, Soo-Yeol ;
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 183~188
Magnetic resonance current density imaging (MRCDI) is a useful method for measuring electrical current density distribution inside an object. To avoid object rotations during the conventional MRCDI scans, we have reconstructed current density component images by applying a spatial filter to the magnetic field data measured both inside and outside the object. To measure the magnetic field outside the object with MRI, we immersed the object in a water tank. To evaluate accuracy of the current density imaging, we have made a conductivity phantom with a corresponding finite element method model. We have compared the experimentally obtained current density images with the ones calculated by the finite element method. The average errors of the reconstructed current density images were 6.6 ∼ 45.4 ％ when the injected currents were 1 ∼ 24 mA. We expect that the current density component imaging technique can be used in diverse biomedical applications such as electrical therapy system developments and biological electrical safety analysis.
Automatic Liver Segmentation of a Contrast Enhanced CT Image Using a Partial Histogram Threshold Algorithm
Kyung-Sik Seo ; Seung-Jin Park ; Jong An Park ;
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 189~194
Pixel values of contrast enhanced computed tomography (CE-CT) images are randomly changed. Also, the middle liver part has a problem to segregate the liver structure because of similar gray-level values of a pancreas in the abdomen. In this paper, an automatic liver segmentation method using a partial histogram threshold (PHT) algorithm is proposed for overcoming randomness of CE-CT images and removing the pancreas. After histogram transformation, adaptive multi-modal threshold is used to find the range of gray-level values of the liver structure. Also, the PHT algorithm is performed for removing the pancreas. Then, morphological filtering is processed for removing of unnecessary objects and smoothing of the boundary. Four CE-CT slices of eight patients were selected to evaluate the proposed method. As the average of normalized average area of the automatic segmented method II (ASM II) using the PHT and manual segmented method (MSM) are 0.1671 and 0.1711, these two method shows very small differences. Also, the average area error rate between the ASM II and MSM is 6.8339 ％. From the results of experiments, the proposed method has similar performance as the MSM by medical Doctor.
The Comparisons of 4 Channel Auditory Brainstem Response for Tracking Auditory Neuro-Pathway
Woo, Jin-Wan ; Lee, Sang-Min ; Hong, Sung-Hwa ; Sung, Young-Ju ; Park, Sook-Kyoung ; Lee, Yong-Hee ; Kim, In-Young ; Kim, Sun-I. ;
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 195~200
The Auditory Brainstem Response (ABR) with a click stimulation in guinea pigs was used to examine the auditory neuro-pathway from the cochlear nucleus to brain. Using multi-channel active electrodes, the 3-dimensional auditory pathway was examined from the cochlea to the inferior colliculus through the brainstem. These results are similar to the well-known neuro-pathway. This study on the multi-channel ABR shows that the positions of the ABR generators move to the central brain and the contralateral pathway. It is generally agreed that the ABR is generated by some structures along the auditory pathway. This study provides some information on the neuro-pathway where the ABR peak is generated.
The Effect of Low Intensity Ultrasound on Osteoblast Activation
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 201~206
The bone formation and re-formation are regulated by two factors that are the synthesis of bone matrix by osteoblast and reabsorption by osteoclast. Recently, there are many studies about regeneration and healing of bone tissue by activation of osteoblast. In general, it is known that the activation of osteoblast is influenced by not only biological stimulus but physical stimulus. In this study, we verified that ostoeblast activation was influenced by low intensity ultrasound. Various ultrasonic properties were used to find out the most appropriate condition on cell activation. From this study, we could confirm that 0.3W/
intensity of ultrasound was the most appropriate to tell activation over whole duty cycles and the increasing rate of tell was the highest at 50％ duty cycle. Thus, it is expected that optimal ultrasonic characteristics on regeneration of bone matrix may be applied to fracture and osteoporosis healing.
Evaluation of the Cochlear Electrode Behavior in the 3D Human Cochlea Model by FEM Analysis
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 207~215
A finite element analysis is used in this study to model 6 kinds of electrode by a genetic program in order to evaluate the mechanical effect on the 3D human cochlea model and the behavior of electrode. Human cochlea is modeled by the spiral-approximation method and the shape of scala tympani is extracted from the mid section of the human cochlea. Contact pressure at the tip and the insertion force are found to be highest when the wires stack horizontally. Axial rotation of electrode is minimal comparing with the stimulating current spread. The results indicate that the electrode stiffness is important to minimize the trauma.
The Classification of the Schizophrenia EEG Signal using Hidden Markov Model
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 217~225
In this paper, a new automatic classification method for the normal EEC and schizophrenia EEC using hidden Markov model(HMM) is proposed. We used the feature parameters which are the variance for statistical stationary interval of the EEC and power spectrum ratio of the alpha, beta, and theta wave. The results were shown that high classification accuracy of 90.9％ in the case of normal person, and 90.5％ in the case of schizophrenia patient. It seems that proposed classification system is more efficient than the system using complicate signal processing process. Hence, the proposed method can be used at analysis and classification for complicated biosignal such as EEC and is expected to give considerable assistance to clinical diagnosis.
Proposition of the EEG Electrode Arrangement at a Frontal Lobe and Rejection of Noise Using a JADE
Journal of Biomedical Engineering Research, volume 25, issue 3, 2004, Pages 227~233
In this paper, it is proposed that the four channel electrode arrangement at a frontal lobe and the noise reduction method using a JADE for the EEG biofeedback system. The proposed electrode arrangement is based on the retina-cornea dipole model. Using JADE and signals which are acquired by the proposed arrangement, four independent components are separated. To estimate a pure EEG component among four components, it is measured that a ratio of alpha wave to the whole signal and then the component that has a maximum value is considered as a pure EEG which the noise is eliminated. As a result of experiments, the proposed methods are effective in reduction of noises during acquisition of the EEG.