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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Biomedical Engineering Research
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Journal DOI :
The Korea Society of Medical and Biological Engineering
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Volume & Issues
Volume 30, Issue 6 - Dec 2009
Volume 30, Issue 5 - Oct 2009
Volume 30, Issue 4 - Aug 2009
Volume 30, Issue 3 - Jun 2009
Volume 30, Issue 2 - Apr 2009
Volume 30, Issue 1 - Feb 2009
Selecting the target year
Challenge and Problem of Medical Robot Surgery Research
Kim, Kwang-Gi ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 271~278
Recently, robot research and development was interesting the inside and outside of the country. Medical robot surgery showed diverse advantages according to advanced technical robot research. Also the academic society, research institute and industry showed concerning to the medical robot system. There is a growing need to introduce medical research for aging society. The surgical landscape is quickly changing because of the major driving force of robotics. Robot system and biomedical engineering research as defined a new engine of development show present ways of future revitalization of medical robot system. Medical robot system will be even more utilized when we keeps trying to combine high biomedical technique, IT research, and robot technique. In this review article, we begin with a short historical review of medical robotics, followed by an overview of clinical applications where robots have been applied.
CoReHA: conductivity reconstructor using harmonic algorithms for magnetic resonance electrical impedance tomography (MREIT)
Jeon, Ki-Wan ; Lee, Chang-Ock ; Kim, Hyung-Joong ; Woo, Eung-Je ; Seo, Jin-Keun ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 279~287
Magnetic resonance electrical impedance tomography (MREIT) is a new medical imaging modality providing cross-sectional images of a conductivity distribution inside an electrically conducting object. MREIT has rapidly progressed in its theory, algorithm and experimental technique and now reached the stage of in vivo animal and human experiments. Conductivity image reconstructions in MREIT require various steps of carefully implemented numerical computations. To facilitate MREIT research, there is a pressing need for an MREIT software package with an efficient user interface. In this paper, we present an example of such a software, called CoReHA which stands for conductivity reconstructor using harmonic algorithms. It offers various computational tools including preprocessing of MREIT data, identification of boundary geometry, electrode modeling, meshing and implementation of the finite element method. Conductivity image reconstruction methods based on the harmonic
algorithm are used to produce cross-sectional conductivity images. After summarizing basics of MREIT theory and experimental method, we describe technical details of each data processing task for conductivity image reconstructions. We pay attention to pitfalls and cautions in their numerical implementations. The presented software will be useful to researchers in the field of MREIT for simulation as well as experimental studies.
The Relation Between Affective Style Based on EEG Asymmetry and Personality on Stress
Seo, Ssang-Hee ; Lee, Jung-Tae ; Chong, Young-Suk ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 288~293
This study investigates the relationship of affective style based on EEG asymmetry, personality, and psychological stress on stress. The experiment consists of three sessions: rest state, landscape scene, and horror film tasks. We used a short horror film to evoke stress. We classified affective style of the individual based on EEG alpha asymmetry: negative bias, positive bias and general. The participants in the negative bias group reported higher levels of stress on the neuroticism of the Big 5 model and Cohen's Perceived Stress Scale. These results demonstrate that participants with the propensity for negative affective style have a nervous temperament and are apt to be stressed.
An Adaptive Classification Algorithm of Premature Ventricular Beat With Optimization of Wavelet Parameterization
Kim, Jin-Kwon ; Kang, Dae-Hoon ; Lee, Myoung-Ho ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 294~305
The bio signals essentially have different characteristics in each person. And the main purpose of automatic diagnosis algorithm based on bio signals focuses on discriminating differences of abnormal state from personal differences. In this paper, we propose automatic ECG diagnosis algorithm which discriminates normal heart beats from premature ventricular contraction using optimization of wavelet parameterization to solve that problem. The proposed algorithm optimizes wavelet parameter to let energy of signal be concentrated on specific scale band. We can reduce the personal differences and consequently highlight the differences coming from arrhythmia via this process. The proposed algorithm using ELM as a classifier show high discrimination performance between normal beat and PVC. From the experimental results on MIT-BIH arrhythmia database the performances of the proposed algorithm are 98.1% in accuracy, 93.0% in sensitivity, 96.4% in positive predictivity, and 0.8% in false positive rate. This results are similar or higher then results of existing researches in spite of small human intervention.
Changes in Event-related Potentials and Gamma-band Activities due to the Difficulty of Auditory Oddball Task
Choi, Jeong-Woo ; Yoon, Jin ; Kim, Chi-Hyun ; Kim, Kyung-Hwan ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 306~310
The purpose of this study is to observe the change in gamma-band cortical activities (GBAs) due to task difficulty. Event-related potential and gamma-band activity were investigated using electroencephalograms recorded during auditory oddball tasks with two difficulty levels. For more difficult task, the amplitude of P300 decreased and the peak latency of P300 was delayed significantly compared to easier task. The induced GBA decreased considerably during the P300 latency period and the peak latency of the induced GBA was delayed for more difficult task. The results imply that the difficulty-related change in cortical information processing may be implemented as a change in the strength of local neuronal association.
Automatic Control System Design and Implementation for a Miniaturized DNA Extraction System using Magnetic Beads
Kim, S. ; Kim, J.D. ; Kim, H.C. ; Kim, J. ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 311~317
An automatic control system is proposed and implemented for a miniaturized DNA extraction system using magnetic bead. A host-local system is employed for the accommodation of the graphical user interface and the basic control function. The functional partitioning into the local and the host system is discussed. The control functions are classified and formalized for the flexible control scenario, which is the input of the proposed system. As the proposed scenario is consists of the sequence of the user-centric actions, the user goal can be easily programmed and modified. The DNA extraction performance of the implemented system was compared with the existing silica-membrane-based method, resulting in the comparable concentration and purity of the extracted DNA. The proposed system is currently being utilized for the development of the DNA extraction system only changing scenario, without any alteration of the system.
Measurement of Magnetic Flux and Induced Current in Magnetic Stimulation for Urinary Incontinence Treatment
Han, Byung-Hee ; Choi, Kyung-Moo ; Cho, Min-Hyoung ; Lee, Soo-Yeol ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 318~326
A simple method for measuring magnetic flux and induced current in magnetic nerve stimulation for urinary incontinence treatment is proposed. Unlike electric nerve stimulation, direct measurement of the induced current in magnetic nerve stimulation is impossible. Since induced currents stimulate nerves or muscles in magnetic nerve stimulation, measuring induced current is very important in validating stimulation efficacy and securing safety. The magnetic flux measuring system is composed of 6 layers with pick-up coils of 7 by 7 in each layer, and the induced current measuring system is composed of 6 layers with 7 concentric circular coils in each layer. The proposed method can be used in the design or performance test of a magnetic nerve stimulator for many clinical applications such as urinary incontinence treatment, activation of peripheral nerves, and transcranial magnetic stimulation.
Development for the Index of an Anesthesia Depth using the Power Spectrum Density Analysis
Ye, Soo-Young ; Baik, Swang-Wan ; Kim, Jae-Hyung ; Park, Jun-Mo ; Jeon, Gye-Rok ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 327~332
In this paper, new index was developed to estimate the depth of anesthesia during general anesthesia using EEG. Analysis of the power spectral density(PSD) of EEG was used to develop new parameters because EEG signal tends to have slow wave during anesthesia. Classifier for index creator was developed by using SEF, BDR and BTR parameters, which are calculated by power spectral density. EEG data were obtained from 7 patients (ASA I, II) during general anesthesia with Sevoflurane. The anesthetic depth evaluation indexes ranged from 0 to 100. The average were
for the states of pre-operation, induction of anesthesia, operation, awaked and post-operation, respectively. The results show that while the depth of anesthesia was evaluated, more accurate information can be provided for anesthetician.
Development of MR Compatible Coaxial-slot Antenna for Microwave Hyperthermia
Kim, T.H. ; Chun, S.I. ; Han, Y.H. ; Kim, D.H. ; Mun, C.W. ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 333~340
MR compatible coaxial-slot antenna for microwave hyperthermia was developed while its structure and size of each part were determined by computer simulation using finite element method(FEM). Its local heating performance was evaluated using tissue-mimic phantom and swine muscles. 2% agarose gel mixed with 6mM/
as a biological tissue-mimic phantom was heated by the proposed antenna driven by a 2.45GHz microwave generator. The temperature changes of the phantom were monitored using multi-channel digital thermometer at the distance of 0mm, 5mm, 10mm and 20mm from the tip center of the antenna. Also muscle tissue of swine was heated for 2 and 5minutes with 50W and 30W of microwave generator powers, respectively, to evaluate the local heating performance of the antenna. MRI compatibility was also verified by acquiring MR images and MR temperature map. MR signals were acquired from the agarose gel phantom using
GRE sequence with 1.5T clinical MRI scanner(Signa Echospeed, GE, Milwaukee, WI, U.S.A.) at Pusan Paik Hospital and were transferred to PC in order to reconstruct MR images and temperature map using proton resonance frequency(PRF) method and laboratory-developed phase unwrapping algorithm. Authors found that it has no severe distortion due to the antenna inserted into the phantom. Finally, we can conclude that the suggested coaxial-slot antenna has an excellent local heating performance for both of tissue-mimic phantom and swine muscle, and it is compatible to 1.5T MRI scanner.
Influences of Inter-electrode Distance on Electrogastrography Measurements
Han, Wan-Taek ; Song, In-Ho ; Kim, In-Young ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 341~346
Cutaneous electrogastrography is the measurement of electrical activity of the stomach on the abdominal surface. The validity of cutaneous electrogastrography is dependent upon the quality of the recording technique. The locations of electrodes are an important issue. We examined the influences of the inter-electrode distance of bipolar leads on electrogastrography measurements. The sensitivity distributions of EGG leads were calculated based on a 2D body fat model and evaluated according to the region of interest sensitivity ratio (ROISR). We simulated the ROISR of the inter-electrode distance in relation to various body fat thicknesses. The distance between the electrodes was proportional to the distance between the ROI and the surface of the abdomen. The results imply that inter-electrode distance can be applied in electrogastrography according to human body fat thickness.
Analysis of Neuronal Activities of Retinal Ganglion Cells of Degenerated Retina Evoked by Electrical Pulse Stimulation
Ryu, Sang-Baek ; Lee, Jong-Seung ; Ye, Jang-Hee ; Goo, Yong-Sook ; Kim, Chi-Hyun ; Kim, Kyung-Hwan ;
Journal of Biomedical Engineering Research, volume 30, issue 4, 2009, Pages 347~354
For the reliable transmission of meaningful visual information using prosthetic electrical stimulation, it is required to develop an effective stimulation strategy for the generation of electrical pulse trains based on input visual information. The characteristics of neuronal activities of retinal ganglion cells (RGCs) evoked by electrical stimulation should be understood for this purpose. In this study, for the development of an optimal stimulation strategy for visual prosthesis, we analyzed the neuronal responses of RGCs in rd1 mouse, photoreceptor-degenerated retina of animal model of retinal diseases (retinitis pigmentosa). Based on the in-vitro model of epiretinal prosthesis which consists of planar multielectrode array (MEA) and retinal patch, we recorded and analyzed multiunit RGC activities evoked by amplitude-modulated electrical pulse trains. Two modes of responses were observed. Short-latency responses occurring at 3 ms after the stimulation were estimated to be from direct stimulation of RGCs. Long-latency responses were also observed mainly at 2 - 100 ms after stimulation and showed rhythmic firing with same frequency as the oscillatory background field potential. The long-latency responses could be modulated by pulse amplitude and duration. From the results, we expect that optimal stimulation conditions such as pulse amplitude and pulse duration can be determined for the successful transmission of visual information by electrical stimulation.