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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Journal of Biomedical Engineering Research
Journal Basic Information
Journal DOI :
The Korea Society of Medical and Biological Engineering
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Volume & Issues
Volume 33, Issue 4 - Dec 2012
Volume 33, Issue 3 - Sep 2012
Volume 33, Issue 2 - Jun 2012
Volume 33, Issue 1 - Mar 2012
Selecting the target year
Robotized Percutaneous Biopsy
Son, Jaebum ; Kim, Kwang Gi ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 105~113
DOI : 10.9718/JBER.2012.33.3.105
Biopsy is a type of histopathological examinations, in which a physician samples cells or tissues from a patient's suspicious lesion. Such a lesion frequently resides deep inside human body, and then a percutaneous biopsy is therefore performed using a thick needle with the assistance of medical imaging such as computed tomography(CT) and magnetic resonance imaging(MRI). Recently modern robotic technology is being introduced to percutaneous biopsy in order to reduce any possible human error and hazard on physicians caused by medical imaging. After medical imaging locates the exact location of lesion, an optimization algorithm plans the path for a biopsy needle. Subsequently, a robot system moves the biopsy needle to the lesion in accurate and safe way with the control of a practitioner or automatically. In this article, we try to look into the state-of-art of percutaneous biopsy using such robotic technology. We classified percutaneous biopsy robots by mechanical characteristics and by imaging technology. Then, advantage and disadvantage of each class type are described as well as the basic description, and a few representative designs for each type are introduced. Current research issues of robotized percutaneous biopsy are subjectively selected for the readers' convenience. We emphasize the basic technology of actuator and sensors compatible with imaging technology to conclude this review.
Blood Glucose Measurement Principles of Non-invasive Blood Glucose Meter: Focused on the Detection Methods of Blood Glucose
Ahn, Wonsik ; Kim, Jin-Tae ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 114~127
DOI : 10.9718/JBER.2012.33.3.114
Recent technical advancement allows noninvasive measurement of blood glucose. In this literature, we reviewed various noninvasive techniques for measuring glucose concentration. Optical or electrical methods have been investigated. Optical techniques include near-infrared spectroscopy, Raman spectroscopy, optical coherence technique, polarization, fluorescence, occlusion spectroscopy, and photoacoustic spectroscopy. Electrical methods include reverse iontophoresis, impedance spectroscopy, and electromagnetic sensing. Ultrasound, detection from breath, or fluid harvesting technique can be used to measure blood glucose level. Combination of various methods is also promising. Although there are many interesting and promising technologies and devices, there need further researches until a commercially available non-invasive glucometer is popular.
Development of Real-time Monitoring System for Muscle Tension by High Intensity Laser Therapy
Hong, Jungsun ; Youn, Jong-In ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 128~134
DOI : 10.9718/JBER.2012.33.3.128
Currently, high-intensity laser therapy (HILT) is increasingly used in various muscle disorders like muscle tension. Our proposed study includes the development of the real-time monitoring system using a myotonometer for HILT. The developed system consists of a piezoelectric sensor and laser distance sensor for muscle stiffness monitoring during the treatments. The results demonstrated that the level of muscle tension was rapidly decreased after 3 minutes of the high-intensity laser treatment when compared to the control group. The combined HILT and realtime muscle tension monitoring system may help to evaluate the therapeutic procedure and efficient treatments for various muscle pains.
Relationship between Endurance Times and Frequency Parameters in Surface EMG during Isotonic Contraction Exercises
Lee, Sangsik ; Go, Jaewook ; Jang, Jeehun ; Park, Wonyeop ; Lee, Kiyoung ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 135~140
DOI : 10.9718/JBER.2012.33.3.135
Previous investigators have shown that the frequency compression is related to the muscle fatigue and the decreasing conduction velocity of muscle fibers. The aim of the present study was to investigate the relationship between endurance times and frequency parameters such as mean power frequency and median frequency in the surface EMG signal during isotonic contractions. Eight healthy subjects performed voluntary isotonic contractions of biceps Brachii muscle until their endurance times which were determined when the subject could no longer follow the contraction cycle. The regressive slopes of mean power frequency and median frequency were used to describe the frequency compression of the surface EMG signal, and to test the predictability of endurance time. As results of experiment, significant correlations were found between endurance time and the regressive slopes of mean power frequency and mean frequency computed over 50%Tend of endurance time.
A Study on the Effects of Chinese Qigong and Kundalini Yoga Meditations on the Heart Rate Variability of Skilled Students
Jang, Dae-Geun ; Jang, Jae-Keun ; Park, Seung-Hun ; Hahn, Minsoo ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 141~147
DOI : 10.9718/JBER.2012.33.3.141
In this paper, we have investigated effects of two specific meditations (Chinese qigong meditation and Kundalini yoga meditation) on the heart rate variability (HRV), which is a well-known quantitative measure of autonomic balance, of skilled students. To analyze the effects, the MIT/BIH physionet database was utilized. The database includes RR intervals of eight skilled Chinese qigong meditators (5 women and 3 men; age range 26-35) and four skilled Kundalini yoga meditators (2 women and 2 men; age range 20-52). RR intervals of each subject were measured before and during the meditations. For HRV analysis, we have used typical four HRV parameters - the low frequency to high frequency power ratio (LF/HF ratio), SD2/SD1 ratio, sample entropy, and fractal dimension. The LF/HF ratio was calculated by the autoregressive spectrum and the SD2/SD1 ratio was derived from the Poincar
plot. The sample entropy was computed from the phase space plot and the fractal dimension was estimated by the Higuchi's algorithm. In the experiments, the Wilcoxon signed rank test was employed because we used small datasets and compared HRV parameters before and during the meditations. As a result, we have found increment of the LF/HF and SD2/SD1 ratios in both meditations; whereas the sample entropy is decreased during the meditations. In addition, the fractal dimension is increased during the Chinese qigong meditation; whereas it is decreased during the Kundalini yoga meditation. The results show that the sympathetic nervous system is generally more activated in skilled Chinese qigong and Kundalini yoga meditators, but the activation of the parasympathetic nervous tone is suppressed.
A Survival Prediction Model of Rats in Uncontrolled Acute Hemorrhagic Shock Using the Random Forest Classifier
Choi, J.Y. ; Kim, S.K. ; Koo, J.M. ; Kim, D.W. ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 148~154
DOI : 10.9718/JBER.2012.33.3.148
Hemorrhagic shock is a primary cause of deaths resulting from injury in the world. Although many studies have tried to diagnose accurately hemorrhagic shock in the early stage, such attempts were not successful due to compensatory mechanisms of humans. The objective of this study was to construct a survival prediction model of rats in acute hemorrhagic shock using a random forest (RF) model. Heart rate (HR), mean arterial pressure (MAP), respiration rate (RR), lactate concentration (LC), and peripheral perfusion (PP) measured in rats were used as input variables for the RF model and its performance was compared with that of a logistic regression (LR) model. Before constructing the models, we performed 5-fold cross validation for RF variable selection, and forward stepwise variable selection for the LR model to examine which variables were important for the models. For the LR model, sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (ROC-AUC) were 0.83, 0.95, 0.88, and 0.96, respectively. For the RF models, sensitivity, specificity, accuracy, and AUC were 0.97, 0.95, 0.96, and 0.99, respectively. In conclusion, the RF model was superior to the LR model for survival prediction in the rat model.
Comparison of Sphygmomanometer, Fully Automatic Electronic Blood Pressure Meters with Standard Digital Blood Pressure Monitor : Pilot Study
Yahng, J.S. ; Lim, H.K. ; Cho, D.H. ;
Journal of Biomedical Engineering Research, volume 33, issue 3, 2012, Pages 155~162
DOI : 10.9718/JBER.2012.33.3.155
Devices to measure the blood pressure of patients are being used without any calibration in a hospital. It is an important to show consistent values when any medical devices measure the same patients regardless they are sphygmomanometer or fully automatic electronic blood pressure meter. We compared sphygmomanometer and fully automatic electronic blood pressure meters with standard digital blood pressure monitor (SDBPM) to evaluate the consistency of the small healthy subjects. We measured the blood pressure from six healthy subjects (three of 20~40 years and three of 40~60 years old). Two sphygmomanometer and two fully automatic electronic blood pressure meters were used and compared with the SDBPM. Blood pressures measured from right and left arms each and were compared. All six healthy subjects showed normal blood pressure values. In general, left blood pressure values showed higher values than right side. Comparing SDBPM, with the other monitors, the systolic pressure showed
34.8% difference and
33.3% for the diastolic pressure. Correlation between SDBPM and Sphygmomanometer was 0.59~0.71, and 0.50~0.70 for fully automated digital BP monitors. It fell in grade-D when we apply the BHS(British hypertension society). AAMI(American association for the advancement of medical instrumentation) also showed unsatisfactory results for the mean value (
5 mmHg) and standard deviation (
8 mmHg). We tested sphygmomanometer and fully automatic electronic blood pressure meters and compared with a standard digital blood pressure monitor. All devices showed inconsistent blood pressures. A reliable calibration system is highly needed for all devices in all hospitals.