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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Journal of Biomedical Engineering Research
Journal Basic Information
Journal DOI :
The Korea Society of Medical and Biological Engineering
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Volume & Issues
Volume 34, Issue 4 - Dec 2013
Volume 34, Issue 3 - Sep 2013
Volume 34, Issue 2 - Apr 2013
Volume 34, Issue 1 - Feb 2013
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Evaluation of Stimulus Strategy for Cochlear Implant Using Neurogram
Yang, Hyejin ; Woo, Jihwan ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 47~54
DOI : 10.9718/JBER.2013.34.2.47
Electrical stimulation is delivered to auditory nerve (AN) through the electrodes in cochlear implant system. Neurogram is a spectrogram that includes information of neural response to electrical stimulation. We hypothesized that the similarity between a neurogram and an input-sound spectrogram could show how well a cochlear implant system works. In this study, we evaluated electrical stimulus configuration of CIS strategy using the computational model. The computational model includes stochastic property and anatomical features of cat auditory nerve fiber. To evaluate similarity between a neurogram and an input-sound spectrogram, we calculated Structural Similarity Index (SSIM). The results show that the dynamic range and the stimulation rate per channel influenced SSIM. Finally, we suggested the optimal configuration within the given stimulus CIS. We expect that the results and the evaluating procedure could be employed to improve the performance of a cochlear implant system.
The Motion Analysis of the limited Wrist Joint During Dart-Throwing Motion by Using Infrared Camera
Park, Chan-Soo ; Park, Jong-Il ; Kim, Kwang Gi ; Jang, Ik-Gyu ; Kim, Tae-Yun ; Lee, Sang lim ; Baek, Goo Hyun ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 55~62
DOI : 10.9718/JBER.2013.34.2.55
Wrist joints consist of irregularly shaped carpal bones and other complicated structures. Thus, evaluating the motion of a wrist joint is a challenging task. In this study, we used an infrared camera to perform a kinematic analysis of a dart-throwing motion. We measured the difference between the movement of a normal wrist and constrained wrist (wrist with a wrist glove) in the dart-throwing motion with thirty six healthy participants. We measured the ulna flexion - radial extension motion using the attached passive marker and analyzed it using Polygon software and SPSS. The pitch and yaw motions with a glove was bigger than the ones without a glove by 20 and 15 degrees, respectively. On the other hand, the roll motion without a glove was bigger than the one with a glove by 7 degree. Wilcoxon signed rank test (p<0.05) confirmed that there are significant differences between the motion with and without a glove. It was found that the magnitude of the pitch and yaw motion with a constrained wrist joint toward radial extension in dart-throwing motion is smaller than the one with a normal wrist joint. However, a normal wrist joint showed a bigger movement in the roll direction.
Comparison of EMG and Muscle Reaction Force to Detect Exercise Intention
Heo, J.H. ; Kim, J.W. ; Kwon, Y.R. ; Eom, Gwang-Moon ; Jeong, K.Y. ; Kwon, D.K. ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 63~68
DOI : 10.9718/JBER.2013.34.2.63
Activeness of exercise is critical for stroke rehabilitation so that application of stimulation in response to patient's intention would be effective in FES cycling. The purpose of this study was to investigate the relationship between muscle reaction force (MRF) and electromyogram (EMG) during cycling exercise, for the future usage of MRF as patients' intention signal. Seven young men (
yrs) participated in this study. Cycling speed was set to 20 RPM and 60 RPM. MRF and EMG were measured in the vastus lateralis muscle of right leg. Active cycling was performed at the maximal load (16 Nm) of an ergometer. Angle dependent artifact in MRF was measured from passive cycling and was subtracted from the MRF of active cycling. The delay of MRF with respect to EMG envelope and their correlation coefficients were derived from the best of cross correlation. MRF was significantly correlated with EMG amplitude in all subjects (p<0.01). Their mean correlations were 0.84 and 0.91 for 20 RPM and 60 RPM, respectively. Mean delay in MRF was 59.14 ms and 53.14 ms for 20 RPM and 60 RPM, respectively. The result suggests that MRF can be used to assess patient's intention for exercise as a substitute to EMG. The method may be applied to FES cycling to encourage patient's effort which is critical for stroke rehabilitation.
Development of Evaluation Method for Drug Release Propreties in Drug Eluting Stent
Song, J.M. ; Baek, H. ; Lee, S.Y. ; Jang, D.H. ; Seo, M.Y. ; Park, G.J. ; Maeng, Eun-Ho ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 69~72
DOI : 10.9718/JBER.2013.34.2.69
The goal of this study is to develop test method for evaluating the drug eluting properties of drug eluting stents (DES). PBS and the detergent solutions, presented by each DES manufacturer, were used for drug release of DES coated with paclitaxel, zotarolimus and everolimus. The drugs which are coating DES were not released by PBS but released by the detergent solutions, finally paclitaxel 83.38%, zotarolimus 103.85% and everolimus 115.78%. It seems that the use of the detergents is necessary in order to release the drugs because those drugs are extremely hydrophobic. In conclusion, using of detergent solutions presented by each manufacturer were suitable for evaluating the drug eluting property of drug eluting stent.
GafChromic RTQA Film Dosimetry for Laser Beam with Photodynamic Therapy
Lee, Byung Koo ; Lim, Hyun Soo ; Kenar, Necla ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 73~79
DOI : 10.9718/JBER.2013.34.2.73
Purpose: The purposes of this study were to measure the dose distribution of Photodynamic therapy(PDT) laser with 635 nm wavelength using GafChromic film. Method & Result: We made each output 300 J by changing mW and sec using the laser beam radiation mode such as C.W(Continuous Wave) mode, Pulse mode and Burst Pulse mode and measured the does at 0 mm and 5 mm of distance from optic fiber catheter end to the film, and at 5 mm distance by changing the angle of the end of the optic fiber catheter as
. The radiated film was scanned and OD(Optical Density) was compared. And two-dimensional isodose curves were obtained and the consistency of shapes was compared. It was confirmed that there was consistency between optic density and the dose radiated on the film when we radiated GafChromic film by changing distance and angle of 300 J output in each radiation mode coordinating mW and sec. Conclusion: In this study, we could identify the stability according to changes in laser beam modes, changes in output according to distance, changes in uniformity according to angle, and beam profiles using GafChromic film, and we could also get two-dimensional isodose curve. It was found that small change in the distance and angle that is made when optic fiber catheter was contacted on the treatment area did not make big effects on the output of beam and the uniformity of dose, and it was also found that GafChromic film could be utilized for the purpose of QA of PDT laser beam.
A Study on Changes in Biomechanical Characteristics of the Foot with Respect to Wedge-type Insole Thickness
Park, T.H. ; Jung, T.G. ; Han, D.W. ; Lee, Sung-Jae ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 80~90
DOI : 10.9718/JBER.2013.34.2.80
Recently, functional insoles of wedge-type it is for the young to raise their height inserted between insole and heel cause foot pain and disease. Additionally, these have a problem with stability and excessively load-bearing during gait like high-heel shoes. In this study, we compared the changes in biomechanical characteristics of foot with different insole thickness then we will utilize for the development of the insole with the purpose of relieving the pain and disease. Subjects(male, n = 6) measured COP(center of pressure) and PCP(peak contact pressure) on the treadmill(140cm/s) using F-scan system and different insole thickness(0~50 mm) between sole and plantar surface during gait. Also, we computed changes of stresses at the foot using finite element model with various insole thickness during toe-off phase. COP moved anterior and medial direction and, PCP was increased at medial forefoot surface,
) with thicker insoles and it was show sensitive increment as the insole thickness was increased from 40 mm to 50 mm. Change of the stress at the soft-tissue of plantar surface,
metatarsal head represents rapid growth(
). Also, lateral moments were increased over the 100% near the
metatarsal as the insole thickness was increased from 0 mm to 30 mm. And it is show sensitive increment as the insole thickness changed 10 mm to 20 mm. As a result, it was expected that use of excessively thick insoles might cause unwanted foot pain at the forefoot region. Therefore, insole thickness under 30 mm was selected.
Simultaneous Imaging Using Combined Optical Coherence Tomography (OCT) and Photoacoustic Microscopy (PAM)
Kim, Sehui ; Lee, Changho ; Han, Seonghoon ; Kang, Hyun Wook ; Oh, Junghwan ; Kim, Jeehyun ; Kim, Chulhong ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 91~96
DOI : 10.9718/JBER.2013.34.2.91
In this study, we developed an integrated optical coherence tomography - photoacoustic microscopy (OCT-PAM) system to simultaneously provide optical absorption and scattering information. Two different laser sources, such as a pulsed laser for PAM and a superluminescent diode for OCT, were employed to implement the integrated OCT-PAM system. The performance of the OCT-PAM system was measured by imaging carbon fibers. We then imaged black and white hairs to demonstrate the simultaneous OCT-PAM imaging capabilities. As a result, OCT can produce 3-D images of both black and white hairs, whereas PAM is only able to image the black hair due to strong optical absorption of black hair.
Sleep Apnea Detection using Estimated Stroke Volume
Lee, Junghun ; Lee, Jeon ; Lee, Hyo-Ki ; Lee, Kyoung-Joung ;
Journal of Biomedical Engineering Research, volume 34, issue 2, 2013, Pages 97~103
DOI : 10.9718/JBER.2013.34.2.97
This paper proposes a new algorithm for sleep apnea detection based on stroke volume. It is very important to detect sleep apnea since it is a common and serious sleep-disordered breathing (SDB). In the previous studies, methods for sleep apnea detection using heart rate variability, airflow and blood oxygen saturation, tracheal sound have been proposed, but a method using stroke volume has not been studied. The proposed algorithm consists of detection of characteristic points in continuous blood pressure signal, estimation of stroke volume and detection of sleep apnea. To evaluate the performance of algorithm, the MIT-BIH Polysomnographic Database provided by Phsio- Net was used. As a result, the sensitivity of 85.99%, the specificity of 72.69%, and the accuracy of 84.34%, on the average were obtained. The proposed method showed comparable or higher performance compared with previous methods.