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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
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Korean Journal of Veterinary Research
Journal Basic Information
Journal DOI :
The Korean Society of Veterinary Science
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Volume & Issues
Volume 49, Issue 4 - Dec 2009
Volume 49, Issue 3 - Sep 2009
Volume 49, Issue 2 - Jun 2009
Volume 49, Issue 1 - Mar 2009
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Relationship between the formation of Schmidt-Lantermann incisure and the localization of neurofascin in rat sciatic nerve
Choi, Hye-Young ; Cho, Ik-Hyun ; Lee, Jong-Hwan ; Nahm, Sang-Soep ; Chang, Byung-Joon ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 273~278
Neurofascin, one of the members of L1CAM, has been known to have some important roles during the development of nerve fibers. In order to investigate the role of neurofascin associated with the formation of Schmidt-Lantermann incisure in the sciatic nerve, the localization of neurofascin was studied with electron microscopy, immuno-fluorescence and immuno-electron microscopy. In the electron microscopy, the first formation of Schmidt-Lantermann incisure was checked at postnatal day 6 and the complete form of incisures traversing the whole myelin sheath began to be observed at postnatal day 8. In the immunofluorescence, neurofascin immunoreactive Schmidt-Lantermann incisures were first checked at postnatal day 6 and dramatically increased with aging by postnatal day 56. In the immunoelectron microscopy, neurofascin immunoreactive gold particles at the incisure forming sites were first observed at postnatal day 6 and the number of gold particles was increased as the animal was getting old by postnatal day 56. According to the present study, neurofascin is likely to have some relationships with Schmidt-Lantermann incisure formation.
Time-course response of epichlorohydrin on epididymal histopathology in rats
Kim, Kang-Hyeon ; Shin, In-Sik ; Lim, Jeong-Hyeon ; Kim, Sung-Hwan ; Park, Na-Hyeong ; Moon, Changjong ; Kim, Sung-Ho ; Shin, Dong-Ho ; Kim, Jong-Choon ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 279~284
This research aimed to investigate the time-course effect of epichlorohydrin (ECH) on epididymal histopathology in Sprague-Dawley rats. Twenty-four male rats were randomly assigned to four groups with 6 rats in each group and were administered a single oral dose of ECH (70 mg/kg) or its vehicle. Six animals each were sacrificed on days 0 (control), 1, 2, and 7 after treatment. During the study period, clinical signs, body weights, reproductive organ weights, testicular spermatid count, epididymal sperm count, motility and morphology, and histopathology were examined. No treatmentrelated effects on body weights and reproductive organ weights were noted at any time point. On the contrary, sperm motility decreased slightly on days 1 and 2 after treatment and then decreased significantly on day 7 after treatment. The first signs of histological changes were the appearance of cell debris in the ducts and vacuolization of the epithelial cells observed in the proximal caput epididymis on day 1 after treatment. The incidences and grades of the histological changes including cell debris in the ducts, epithelial vacuolization, oligospermia, and epithelial disruption increased on day 2 and then decreased slightly on day 7 after treatment. These results show that a single oral dose of 70 mg/kg ECH to male rats results in cell debris in the ducts and vacuolization of the epithelial cells in the proximal caput epididymis, followed by reversible oligospermia, epithelial disruption, and decreased sperm motility.
Superfecundation induction by intrauterine insemination with different frozen-thawed canine semen and parentage test using microsatellite analysis
Lee, Ji Hye ; Kim, Keun Jung ; Choi, Seon A ; Li, Xiaoxia ; Kim, Eun Young ; Oh, Hyun Ju ; Lee, Byeong Chun ; Kim, Hye Jin ; Park, Byung Kwon ; Kim, Min Kyu ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 285~290
This study was performed to investigate the possibility of superfecundation by surgical intrauterine artificial insemination in dogs of confirmed genetic pedigree. Artificial insemination was performed on 3 days after ovulation with
spermatozoa. Five puppies were delivered on 60 days after insemination. The ratio of the number of newborns to the number of corpora lutea was 83.3% (5/6). Parentage analysis with 10 canine-specific microstatellite markers demonstrated that one puppy was genetically relative to the sire-A family and four puppies were genetically relative to the sire-B. The present study demonstrated that two kinds of puppies with different genetic pedigree can be produced by surgical uterine insemination of semen of individual dog into each uterine horn of a bitch.
Toxoplasmic meningoencephalitis in a stray cat in Korea
Kim, Ha-Young ; Bae, You-Chan ; Woo, Gye-Hyeong ; Byun, Jae-Won ; Jung, Byeong-Yeal ; Park, Jung-Won ; Chae, Hee-Sun ; Choi, Jae-Yong ; Nakayama, Hiroyuki ; Hwang, Eui Kyung ; Joo, Yi-Seok ; Lee, O-Soo ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 291~295
A dead stray cat was necropsied for zoonotic feline disease monitoring. Grossly, there were no specific lesions. Major microscopic lesions included lymphocytic meningoencephalitis, malacia, and tissue cysts in the cerebral and cerebellar cortex. The size and shape of tissue cysts were identical to those of Apicomplexa including Toxoplasma (T.) gondii. Bradyzoites in the tissue cyst were strongly positive for T. gondii by immunohistochemistry. Electron microscopy revealed that bradyzoites within the tissue cyst were similar to the morphological features of T. gondii. Fresh tissue samples were examined by a polymerase chain reaction assay and resulted in a specific band of T. gondii only in the brain. Based on the results, this case was diagnosed as toxoplasmosis. This is the first case of toxoplasmic meningoencephalitis in a cat in Korea.
The disease status of stray dogs admitted to an animal shelter in Gwangju, Korea
Myung, Bo Young ; Yi, Yu Kyung ; Paik, Il Youp ; Chung, Gyung Min ; Lim, Sun ; Suh, Guk Hyun ; Kang, Seong Soo ; Shin, Sung Shik ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 297~307
Animal shelters are potentially vulnerable to constant exposure to a variety of diseases for both animals and humans, because thousands of animals with unknown histories are being admitted to each shelter on a yearly basis in Korea. The control of disease spread, therefore, can be a major challenge to veterinarians in most shelters. This study investigated the health status of stray dogs admitted to the Gwangju Animal Shelter during the year of 2008, and analyzed types of disorders at the time of admission as well as newly acquired diseases while housed in the shelter. Canine heartworm disease was the most prevalent infection among stray dogs at the time of admission, while the respiratory disorder was the most common shelteracquired disease. The majority of dogs (93.5%) was either small or middle-sized breeds with Maltese (19.7%) and Shih Tzu (16.0%) being the most commonly found stray dogs. Out of 1,143 dogs admitted to the shelter, owners of 128 dogs (11.2%) visited the shelter and found their lost dogs, while 518 dogs (45.3%) were adopted to new families. Results of this study strongly indicate that stray dogs in Korea are exposed to a variety of diseases and the disease control by veterinarians is one of the most important aspects of the shelter management.
Investigation on an epidemic of tuberculosis in dairy cattle farms In Jeongeup, Korea
Yoon, Hachung ; Moon, Oun-Kyong ; Kim, Youn-Ju ; Cho, Bum-Joon ; Lee, Soo-Doo ; Lee, Jeong-Won ; Lee, Sang-Jin ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 309~317
The present study describes an investigation on an epidemic of Tuberculosis (TB) which has been occurred among dairy cattle farms in Jeongeup, Jeollabuk-do since 2007. The investigation was performed in three ways as follows: 1. Collecting information about bovine TB outbreaks using investigation reports, an on-the-spot and tracing-back investigations; 2. Analyzing the outbreak pattern; 3. Establishing hypothesis and performing statistical analysis on potential risk factors. In the early 2000s, TB outbreaks were sporadically reported in beef cattle, and only a small number (
) of reactors was confirmed in each of outbreak farms. The number of TB outbreaks has been suddenly increased from 2007, mainly in dairy cattle farms. And these outbreaks were temporarily clustered during the period, from March 2007 to April 2009 (relative risk, RR = 13.7, p < 0.001). And two spatial clusters of which radiuses were 0.3 km (RR = 6.9, p < 0.001) and 0.9 km (RR = 3.6, p < 0.01). The analysis to find risk factors was performed on 99 dairy farms (21 outbreaks), which are located in the most seriously affected village during 2007-2009. Middleman (odds ratio, OR = 47.4, p < 0.05) and raw milk collecting system (OR = 6.9, p < 0.05) were recognized as with the highest association. Considering the fact that all the outbreak farms except one had their own manure composting tank, it might be that the manure containing pathogen was leaked from tank and transmitted to other farms by fomites such as middleman or raw milk collecting system.
Random amplification of polymorphic DNA typing of Listeria monocytogenes isolates from animal products
Lee, Chul-Hyun ; Son, Won-Geun ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 319~328
This study investigated the epidemiology of Listeria (L.) monocytogenes, a food-borne pathogen. The epidemiology of food-borne pathogens is of great importance for clarifying bacterial origin and preventing bacterial contamination and infection. This work examined 68 L. monocytogenes strains, including 11 reference strains and 57 isolates from imported US beef, domestic meats (beef, pork, chicken meat), raw milk, and milk plants. The random amplified polymorphic DNA (RAPD) techniques were optimized to develop a standard molecular epidemiological analysis of L. monocytogenes. There was great genetic variability among the isolates, which produced 24 and 34 RAPD patterns with primer HLWL85 and HLWL74, respectively. The discriminatory power of the RAPD methods with HLWL85 and HLWL74 primer were very high (DI = 0.957; S
95%). Some RAPD types were specific to origin. A few RAPD types were specific for L. monocytogenes strains belonging to a particular serotype. Using the HLWL85 primer, the strains isolated from milk plants could be distinguished from the other strains. And using the HLWL74 primer, the strains isolated from imported beef (US) could be distinguished completely from the other strains.
Partial Budget Modeling of Economic Losses of Aujeszky's Disease
Pak, Son-Il ; Park, Choi-Kyu ; Moon, Oun-Kyong ; Yoon, Hachung ; Lee, Byeong-Yong ; Lee, Sang-Jin ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 329~334
Aujeszky's disease (AD) is a respiratory, infectious viral illness associated with high mortality, especially in neonatal piglets and has frequently been considered an economically important disease in many endemic countries. Although AD is still occurring in a geographically defined region in Korea, little attention has been paid to the economics of AD. In this study, partial budget technique was used to develop a simulation model to measure financial losses following the disease epidemic in a swine operation utilizing stochastic or deterministic parameters from the literatures and the index case herd of AD occurred in 2005, where available and applicable. For the infected case herd with a 12500-pig, the total economic loss for this operation was estimated to be about 199 million Korean won (95% confidence interval [CI] 148,645,000-250,741,000). Given net loss due to death of a pig at sow level was 119,000 won, total loss for the case herd with 1200 sows accounted for 143 million won (95% CI 92,599,000-193,729,000). The net loss of the death of one pig at growing and fattening level resulted in loss of 46,000 won (95% CI 40,000-53,000) and 126,000 won (95% CI 122,000-131,000), respectively. Taking into account for the number of pigs raised in the case herd, total loss amounted to 8 million won (95% CI 7,167,000-9,347,000) and 12 million won (95% CI 11,959,000-12,891,000), for growers and fatteners, respectively, assuming 63% of saved feed intake when a pig dies halfway through the respective period. Under the model's assumptions, suckling pig mortality was the major factors of loss in estimating the economic consequences (approximately 71.8% of the total loss). The high economic losses of a herd infected with AD suggest that the effective and region-specific control measures should be implemented in disease endemic foci.
Pathogenicity of Lactobacillus pentosus PL11 isolated from eel (Anguilla japonica) intestine and single oral toxicity of its culture broth in rats
Lee, Joong-Su ; Jang, Seung-Hee ; Choi, Myung-Jin ; Gebru, Elias ; Park, Seung-Chun ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 335~343
The pathogenicity and acute toxicity of Lactobacillus (L.) pentosus PL11 from eel (Anguilla japonica) were investigated using male and female Sprague-Dawley rats. The pathogenicity of L. pentosus PL11 was examined after treating the rats with
CFU/mL doses of L. pentosus PL11 culture or 0.85% NaCl (Control) intragastrically. For acute toxicity studies, rats were treated with dried culture broth of L. pentosus PL11 at doses of 5,000 mg/mL, 2,500 mg/mL, 1,250 mg/mL or 625 mg/mL or Lactobacilli MRS broth (Control), and clinical signs or mortalities were monitored for two weeks. The results of the present investigation revealed no mortalities or obvious clinical signs in rats administered with the live bacterial cultures or dried culture broth at any investigated dose level. Also, no significant differences were observed in net body weight gain, gross pathological findings, feed and water consumption and body temperature among the different treatment groups and between the treated and control rats. It can be concluded from the above findings that L. pentosus PL11 is a safe probiotic strain with potential as feed additive to increase the feed efficiency or health of fish.
Effect of PCB118 on expression of COX-2 and cPLA2 in rat testes
Han, Dae-Yong ; Park, Kwang-Il ; Park, Hyeon-Soo ; Kang, Sang-Rim ; Cho, Jae-Hyeon ; Lee, Hu-Jang ; Kim, Eun-Hee ; Kim, Gon-Sup ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 345~349
Polychlorinated biphenyls (PCBs) are synthetic organic compounds with two benzene rings and well known environmental pollutants. This study examined the effect of persistent exposure to 2,
,5-pentachlorobiphenyl (PCB118) on the proinflammatory and proapoptotic factors in male rats. Male Sprague Dawley rats were administered weekly intraperitoneal injections of either PCB118 (20 mg/kg) dissolved in corn oil or corn oil alone. One week after 2 and 5 administrations, the rats were sacrificed by a pentobarbital injection. The effect of PCB118 on the expression of cyclooxygenase 2 (COX-2), cytosolic phospholipase A2 (cPLA2), peroxisome proliferator-activated receptor gamma, Bcl and Bcl-2-associated X protein (BAX) was investigated. The level of COX-2 and cPLA2 expression was higher in the PCB118-treated rats than the control. These results suggest that PCB118 has a proinflammatory effect in rats.
Diaphragmatic hernia in a Jeju horse (crossbred) broodmare
Yang, Jaehyuk ; Koh, Yang-Nam ; Hwang, Kyu-Kye ; Lim, Yoon-Kyu ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 351~354
Diaphragmatic hernias, whether congenital or acquired (traumatic), are rarely observed in the horse. Acquired diaphragmatic hernias typically occur secondary to trauma or an increase in intraabdominal pressure due to falling, heavy exercise, or parturition. Diaphragmatic herniorrhaphy is difficult to perform in adult horses and the horses with symptomatic diaphragmatic hernias usually die. A 10- year old, 340 kg, Jeju horse (crossbred) broodmare with sudden onset of gait disorder and a moderate emaciation was examined. Findings on physical examination included conjunctivitis, dehydration, shallow breathing, dyspnea, weaken heart beat, lack of auscultatable sounds from the gastrointestinal tract, and anorexia. Rectal temperature was
and respiratory rates were moderately increased. There were slight signs of acute colic. The broodmare died one day after non-specific treatment of fluids, nutriment, antibiotics and non-steroidal anti-inflammatory drug. The cause of death was strangulation of the small intestine through a diaphragmatic hernia. The rent was about 2 cm in diameter and located in the central right part of diaphragm. Around 60 cm of small intestine was protruded into thoracic cavity through the rent. The cause of the hernia could not be ascertained. The broodmare had been pastured with many other horses, and the groom had not noticed any aggressive behavior among them. It was, however, speculated that trauma by stallion's attack may have been the cause of the diaphragmatic hernia, because the new horse may be the object of behaviors ranging from mild threats to seriously aggressive kicking, squealing, rearing, and biting.
Hypoparathyroidism in a diabetic dog
Lee, Hye-Jin ; Lim, Soo-Jung ; Lee, Sun-Hee ; Song, Eun-Sik ; Song, Kun-Ho ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 355~359
A miniature schnauzer (8 years old, male castrated), diagnosed as diabetes mellitus 6 months ahead, were referred to the Veterinary Medical Teaching Hospital of our University with hindlimb stiffness, facial rubbing and tetany. Serum chemistry showed severe hypocalcemia, hypomagnesemia, and measured iPTH (intact pharathyroid hormone) concentration was low (< 3.0 pmol/L). Consistent rate injection of calcium gluconate (282 mg/kg over 30 min) resulted in prompt relief of the tetany. Then typical treatment for hypoparathyroidism (calcium gluconate and dihydrotachysterol per os) with magnesium administration could control the neuromuscular signs. Diabetes mellitus is being controlled by insulin therapy and prescription diet. Hypomagnesemia in diabetic dog may be induced hypoparathyrodism.
Rhabdoid tumor in the gluteal region of a Shit-tzu dog
Chung, Jae-Yong ; Do, Sun-Hee ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 361~363
Rhabdoid tumor is an aggressive neoplasm of animals and human. It is similar with rhabdomyosarcoma histopathologically. But cellular origin of this neoplasm showed no striated muscle origin by immunohistological and ultrastructural studies. Castrated male Shit-tzu dog, 6 years old, had a mass in the left gluteal region near to the tail. The mass was examined histopathologically and immunohistologically. Histopathologically, the tumor was consisted of large polygonal cell with abundant eosinophilic cytoplasm. The nuclei in some cells were marked eccentrically located. Immunohistochemically, many neoplastic cells were positive for vimentin. These findings were similar to histopathological and immunohistological features of human rhabdoid tumor and few rhabdoid tumors in animals.
Hyperinsulinism in a dog with beta-cell neoplasia (insulinoma)
Yu, Do-Hyeon ; Lee, Jong-Hyun ; Song, Ru-Hui ; Noh, Dong-Ho ; Li, Ying-Hua ; Lee, Mi-Jin ; Cho, Ara ; Kim, Bumseok ; Park, Jinho ;
Korean Journal of Veterinary Research, volume 49, issue 4, 2009, Pages 365~368
A six-year-old female cocker spaniel presented with recurring episodes of pelvic limb weakness and intermittent seizures. Laboratory analysis revealed marked hypoglycemia and an elevated serum insulin concentration. A pancreatic beta-cell tumor at stage III (
) was diagnosed based on serial blood glucose and insulin measurements along with diagnostic imaging. The patient survived for 140 days after diagnosis with medical management, including frequent feeding and prednisolone therapy. On necropsy, necrosis and masses in the peripancreatic omentum and liver were found; pancreatic beta-cell neoplasia with metastasis to the liver was confirmed by histopathologic examination. This case reports hyper-insulinism in a dog presenting with hypoglycemic seizures.