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REFERENCE LINKING PLATFORM OF KOREA S&T JOURNALS
> Journal Vol & Issue
Korean Journal of Veterinary Research
Journal Basic Information
Journal DOI :
The Korean Society of Veterinary Science
Editor in Chief :
Volume & Issues
Volume 55, Issue 4 - Dec 2015
Volume 55, Issue 3 - Sep 2015
Volume 55, Issue 2 - Jun 2015
Volume 55, Issue 1 - Mar 2015
Selecting the target year
Efficacy of orally administered ginseng stem and leaf in chickens
Park, Soyeon ; Lee, Kwang-Yeal ; Cho, Youngjae ; Park, Bokyoung ; Kim, Kiju ; Lee, Na-Rae ; Kim, Dong-Gun ; Kim, Young-Hee ; Hahn, Tae-Wook ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 1~7
DOI : 10.14405/kjvr.2015.55.1.1
Ginseng has been widely used in Korea as a natural medicine due to its saponin contents. Although the total amount of ginseng stem and leaf saponins (GSLS) is 4~5 times higher than that of saponin in the root, the root is mainly used. This is due to two reasons: nervous system-stimulant activity of GSLS and pesticide residues in GSLS. In this study, residual agricultural pesticides were removed from GSLS using two types of bacterial treatments. Two GSLS treatment groups of chickens (GSLS-1 and GSLS-2) were established. The chickens were fed 0.4% GSLS-1 or GSLS-2 mixed with crop. We then evaluated the effects of GSLS on bodyweight and several immune parameters. At the end of the experiments, chickens fed GSLS-1 and red ginseng saponin had significantly higher growth rates (16.6% and 8.0%, respectively) compared to the vaccine control group treated with Noblis Salenvac-T. The group fed GSLS-1 also had the highest IgG titer that was significantly different at the end of experiments compared to the other groups. These findings imply that GSLS-1 is a good candidate feed additive for the chicken industry.
Comparison of transport media for the isolation and detection of Brachyspira hyodysenteriae
Cho, Se-Ji ; Kim, Jong Wan ; Kim, Ha-Young ; Oh, Sang-Ik ; Jeong, So Jeong ; Jung, Ji-A ; Cho, Ara ; Lee, Myoung-Heon ; Cho, Ho-Seong ; Byun, Jae-Won ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 9~12
DOI : 10.14405/kjvr.2015.55.1.9
Brachyspira (B.) hyodysenteriae is a causative agent of swine dysentery that is responsible for death and economic losses in the pig industry. It is imperative that clinical samples be delivered fresh for accurate diagnosis. The viability and DNA detection of B. hyodysenteriae using lab-made (phosphate buffered saline and modified tryptic soy broth) or commercial transport media (C, D, and E) were compared by culturing and real-time PCR at
or room temperature (RT), respectively. B. hyodysenteriae grown in D (Anaerobe Systems, USA) and E (Starplex Scientific, Canada) media was viable for 4 days at
and RT. However, B. hyodysenteriae in A, B, and C (culture swab; BD Biosciences, USA) media were not recovered after 2 days at RT. Ct values for real-time PCR at
and RT ranged from
(B), respectively. Considering the field conditions, it is important that transport media is used for specimen isolation and PCR to obtain an accurate diagnosis of swine dysentery.
Biological activities and acute oral toxicity of citronella and lemongrass oil
Park, Ji-Yong ; Kim, Jin-Yoon ; Jang, Seung-Hee ; Kim, Hae-Jung ; Lee, Seung-Jin ; Park, Seung-Chun ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 13~20
DOI : 10.14405/kjvr.2015.55.1.13
This study was performed to investigate the antibacterial, antioxidant, and termite repellent effects of citronella oil (CiO) and lemongrass oil (LO). When the antibacterial activity against Staphylococcus (S.) aureus with various levels of antibacterial resistance were tested, a 0.05% concentration of CiO and LO completely inhibited the growth of all tested S. aureus strains. Evaluation of the antioxidant effect demonstrated that the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of CiO was 2~3 times greater than that of LO. Among trial products made with various combinations of CiO and LO, a CiO : LO ratio of 6 : 4 had the most potent termite repellent effects. Assessment of acute toxicity of the trial product showed that the
was more than 2,000 mg/kg. Based on the above results, CiO and LO have antibacterial, antioxidant, and termite repellent activities. Therefore, both compounds could be potential termites repellent reagents.
Protective effect of Hizikia fusiforme on radiation-induced damage in splenocytes
Kim, Areum ; Bing, So Jin ; Cho, Jinhee ; Ahn, Ginnae ; Lee, Ji-Hyeok ; Jeon, You-Jin ; Lee, Byung-Gul ; Jee, Youngheun ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 21~30
DOI : 10.14405/kjvr.2015.55.1.21
The immune system is specifically sensitive to oxidative stress induced by ionizing radiation because of its rapid proliferative activity. For this reason, an instructive immune system is one of the best ways to minimize side effects, such immunodeficiency, of gamma radiation. Over the past few decades, several natural plants with antioxidant and immunomodulatory properties have been identified as adjuncts for nontoxic and successful radiotherapy. Hizikia fusiforme extract (HFE) containing plentiful dietary fiber and fucoidan is known for its instructive antioxidant capacity, immunomodulation abilities, and immune activation. In this study, we determined whether HFE protects radiosensitive immune cells from gamma radiation-induced damage. C57BL/6 mice were irradiated with gamma-ray. The effect of HFE on the ionizing radiation damage of immune cells was then evaluated with an MTT assay, 3H-thymidine incorporation assay, and PI staining. We found that HFE stimulated the proliferation of gamma-ray irradiated immune cells without cytotoxic effects. We also observed that HFE not only decreased DNA damage but also reduced gamma radiation-induced apoptosis of the immune cells. Our results suggest that HFE can protect immune cells from gamma-ray damage and may serve as an effective, non-toxic radioprotective agent.
rpoB gene sequencing for phylogenetic analysis of avian pathogenic Escherichia coli
Kwon, Hyuk-Joon ; Seong, Won-Jin ; Kim, Tae-Eun ; Won, Yong-Jin ; Kim, Jae-Hong ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 31~39
DOI : 10.14405/kjvr.2015.55.1.31
The present study was conducted to determine the full rpoB and eight house-keeping gene sequences of 78 and 35, respectively, avian pathogenic E. coli (APEC) strains. Phylogenetic comparison with 66 E. coli and Shigella strains from GenBank and EMBL was also conducted. Based on the full rpoB sequence, 50 different rpoB sequence types (RSTs) were identified. RST 1 was assigned to a major RST that included 34.7% (50/144) of the analyzed strains. RST 2 to RST 50 were then assigned to other strains with higher nucleotide sequence similarity to RST 1 in order. RST 1, 11, and 23 were mixed with APEC along with human commensal and pathogenic strains while RST 2, 6, 9, 13-15, 22, 24, 25, 33, 34, 36, and 41 were unique to APEC strains. Only five APEC strains grouped into RST 32 and 47, which contained human pathogenic E. coli (HPEC). Thus, most of the APEC strains had genetic backgrounds different from HPEC strains. However, the minor APEC strains similar to HPEC should be considered potential zoonotic risks. The resolution power of multi-locus sequence typing (MLST) was better than RST testing. Nevertheless, phylogenetic analysis of rpoB was simpler and more economic than MLST.
Comparison of antibiotic resistance profiles for Escherichia coli isolated from wild boar and domestic pig fecal samples
Yoo, Sung J. ; Sunwoo, Sun Young ; Seo, Sang Won ; Lyoo, Young S. ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 41~46
DOI : 10.14405/kjvr.2015.55.1.41
Increasing presence of wild boar around cities and suburban areas is a growing concern with respect to agronomy, environmental ecology, and public safety. In this study, antibiotic resistance profiles of Escherichia (E.) coli isolated from wild boar and domestic pig fecal samples were compared. Eighty E. coli samples were isolated from wild boars. Resistance of the bacteria to 14 common antimicrobial agents used in human and veterinary medicine was evaluated. Ninety-five E. coli isolates from domestic pig farms were used for comparison. Common and distinct antibiotic resistance patterns were observed when comparing wild boar and domestic pig isolates, indicating that wild boars may significantly influence environmental microbiology.
Usefulness of ultrasound contrast media for cardiac output measurement with echocardiography
Yun, Je Woong ; Yeon, Seong Chan ; Lee, Hee Chun ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 47~52
DOI : 10.14405/kjvr.2015.55.1.47
The purpose of this study was to determine if contrast media would enhance visualization of the endocardium for assessment of left ventricle (LV) function. In addition, differences between pre- and post-contrast evaluation for the cardiac output measurements including the modified Simpson's method and automated contour tracking (ACT) method were examined. Ten clinically healthy adult beagle dogs (three males and seven females) between 2~3 years old and weighing 6.6~10.8 kg were used. Echocardiographic examinations were performed to compare pre- and post-contrast LV endocardium visualization using a segmental scoring method. Two different methods for measuring cardiac output were also compared. LV visualization was significantly enhanced in post-contrast echocardiography (p < 0.01). Significant differences between pre- and post-contrast measurements for the modified Simpson's method (p < 0.05) were also observed. No significant difference was found for the ACT method. Contrast echocardiography provides better LV chamber opacification and significantly improves wall segment visualization. Furthermore, contrast echocardiography for measuring cardiac output is helpful for the modified Simpson's method.
Genetic analysis of env and gag gene fragments of bovine leukemia virus identified in cattle from Korea
Kim, Yeon-Hee ; Lee, Eun-Yong ; Oem, Jae-Ku ; Kim, Seong-Hee ; Lee, Myoung-Heon ; Lee, Kyoung-Ki ; Park, Se-Chang ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 53~56
DOI : 10.14405/kjvr.2015.55.1.53
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis. This study was conducted to clarify the molecular characteristics of BLVs obtained from a specific region in Korea. Proviral BLVs were detected in anti-BLV antibody-positive blood samples by PCR. Env and gag fragments were sequenced and compared to previously published reference sequences. Analysis of the env gene sequence revealed that the YI strain was highly similar to genotype 1, including United States and Japanese strains. The gag gene sequence had the highest degree of similarity with a Japanese strain.
Distribution and accumulation of
Lu-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles in the tissues of ICR mice
Hue, Jin Joo ; Lee, Hu-Jang ; Nam, Sang Yoon ; Kim, Jong-Soo ; Lee, Beom Jun ; Yun, Young Won ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 57~60
DOI : 10.14405/kjvr.2015.55.1.57
To investigate kinetics of free
-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION), suspensions were intravenously injected into the tail vein of mice at a dose of
/mouse or 15 mg/kg body weight, respectively. Free
radioactivity levels were highest in kidney followed by liver and lung 1 day post-injection.
-labeled TCL-SPION radioactivity in liver and spleen was significantly higher compared to that of other organs throughout the experimental period (p < 0.05). Radioactivity in blood, brain, and epididymis rapidly declined until 28 days. Based on these results, TCL-SPION could be a safe carrier of therapeutics.
Seroprevalence of porcine proliferative enteropathy before initiating vaccine marketing in Korea
Yeh, Jung-Yong ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 61~63
DOI : 10.14405/kjvr.2015.55.1.61
Proliferative enteropathy caused by Lawsonia intracellularis is one of the most common enteric diseases in pigs. The objective of this study was to determine the prevalence of serum antibodies against L. intracellularis in the general swine population of Korea from 2005 to 2008. In total, 8,008 swine serum samples obtained from 1,001 herds were tested. The samples were analyzed with an immunoperoxidase monolayer assay to detect anti-L. intracellularis antibodies. The overall 4-year average true prevalence was 40.0% (CI: 39.4 - 40.6%) at the individual animal level and 71.9% (CI: 70.3-73.4%) at the herd level.
Primary renal fibrosarcoma with local invasion into the mesenteric membrane of a mongrel dog
Park, Hyun-Ah ; Jeong, Chang-Woo ; Kim, Gui-Soo ; Kim, Han-Jun ; Do, SunHee ; Park, Hee-Myung ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 65~69
DOI : 10.14405/kjvr.2015.55.1.65
A 14-year-old, 7.4 kg, neutered male mongrel dog presented with vomiting, anorexia, and hematuria starting 3 days prior to admission. Serum biochemical profiles indicated severe azotemia. Computed tomography revealed loss of normal left kidney structure. The organ was 1.5 to 2 times larger than the right kidney with mixed attenuation. Histopathologic examination was performed after nephrectomy. The renal mass and mesenteric membrane were positive for vimentin and stained blue with Masson's trichrome. In conclusion, this was a rare occurrence of primary renal fibrosarcoma, most likely originated from the renal capsule, with local invasion into the mesenteric membrane.
Embryonal rhabdomyosarcoma in the abdominal cavity of an aged Sprague-Dawley rat
Kim, Hak-Soo ; Jeon, Byung-Suk ; Lee, Byung-Woo ; Yoon, Byung-Il ;
Korean Journal of Veterinary Research, volume 55, issue 1, 2015, Pages 71~73
DOI : 10.14405/kjvr.2015.55.1.71
We report a spontaneous embryonal rhabdomyosarcoma in the abdominal cavity of an aged (88-week-old) Sprague-Dawley rat. The animal had a firm lobulated
mass in the abdominal cavity that was whitish to tan with necrotic and hemorrhagic plaques. Microscopically, the mass contained nodules with spindle or globoid shaped neoplastic cells with abundant eosinophilic cytoplasm and round or elongated nuclei mixed with other spindle cells with a filamentous appearance and scanty cytoplasm. Multinucleated cells and cross-striations were also observed. The neoplastic cells were positive for vimentin, desmin, and alpha-smooth muscle actin, especially the small spindle cells.