While the recent high demand for mega-tall buildings has led to the development of high-performance and high-strength steels, the requirements for architectural-structure-performance steel have been raised as engineers recognize the potential damage that an earthquake can wreak on a tall building. A 600MPa-class steel has emerged to meet such need, and many studies are currently exploring its practical applications on civil engineering works and mega-tall buildings. The available data on the horizontal-force behaviors of structures built with such new steel, however, are still insufficient. There is an urgent need to look into its design data, especially its toughness, and to compare the plastic strain ratios of column-to-beam connections using high-strength steel and regular steel. One of the first studies on the behavior of a column-to-beam connection using 600MPa-class steel (SM570 TMC), this thesis analyzes such steel's structural performance by conducting a structural test on seismic resistance on a full-scale column-to-beam welded connection with non-scallop and recommended-scallop details. Compared with the previous studies on SM490, this thesis evaluates the weldability of SM570 TMC and presents the latter's seismic design data for use in testing its practical application.