• Title, Summary, Keyword: 뇌 선호도

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Effects of Korean Red Ginseng on White Matter Microstructure and Cognitive Functions : A Focus on Intrusion Errors (고려 홍삼이 대뇌 백질 미세구조 및 인지기능에 미치는 효과 : 침입 오류를 중심으로)

  • Jeong, Hyeonseok S.;Kim, Young Hoon;Lee, Sunho;Yeom, Arim;Kang, Ilhyang;Kim, Jieun E.;Lee, Junghyun H.;Ban, Soonhyun;Lim, Soo Mee;Lee, Sun Hea
    • Korean Journal of Biological Psychiatry
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    • v.22 no.2
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    • pp.78-86
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    • 2015
  • Objectives Although ginseng has been reported to protect neuronal cells and improve various cognitive functions, relationship between ginseng supplementation and response inhibition, one of the important cognitive domains has not been explored. In addition, effects of ginseng on in vivo human brain have not been investigated using the diffusion tensor imaging (DTI). The purpose of the current study is to investigate changes in intrusion errors and white matter microstructure after Korean Red Ginseng supplementation using standardized neuropsychological tests and DTI. Methods Fifty-one healthy participants were randomly allocated to the Korean Red Ginseng (n = 26) or placebo (n = 25) groups for 8 weeks. The California Verbal Learning Test was used to assess the number of intrusion errors. Intelligence quotient (IQ) was measured with the Korean Wechsler Adult Intelligence Scale. Depressive and anxiety symptoms were evaluated using Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, and Hopkins Symptom Checklist-25. The fractional anisotropy (FA) was measured from the brain DTI data. Results After the 8-week intervention, Korean Red Ginseng supplementation significantly reduced intrusion errors after adjusting age, sex, IQ, and baseline score of the intrusion errors (p for interaction = 0.005). Change in FA values in the left anterior corona radiata was greater in the Korean Red Ginseng group compared to the placebo group (t = 4.29, p = 0.04). Conclusions Korean Red Ginseng supplementation may be efficacious for improving response inhibition and white matter microstructure integrity in the prefrontal cortex.

성별에 따른 향 선호도 결정에 미치는 주관적 감성요인

  • 백은주;이윤영;김완석;이배환
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • pp.148-153
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    • 1998
  • 향은 방향성 또는 휘발성 물질에 il해 코의 점막을 통해 흡입되어 여러 감성의 변화와 뇌파등 생체 신호의 변화를 초래하고 또한 풍부한 감성도 유발한다. 특히 기억력에 관련된 원시 감정을 유발하고 생체에서 나오는 phermone(페르몬)은 행동 양식까지 영향을 미친다. 또한 질환치료에도 적용되거나 증상의 경감, 예방효과 등을 보여주는 aromatherapy는 매우 유망한 분야이다. 본 연구에서는 이러한 페르몬 향과 aromatherapy에 사용되는 essential oil등을 이용하여 주관적 감성 평가를 실시하고 이를 통계분석하여 이들 여러 종류의 향들의 자극으로 유발되는 감성의 특징을 밝혀내고자 하였다. 둘째로 향의 선호도를 결정하는데 어떠한 감성요인이 작용하는지를 알고자 하였다. 실험에 사용된 향은 26종류이고 총 33명의 지원자가 참여하였다. 설문지는 18문항을 선별하여 4가지 유형으로 작성한 후 유형별로 데이타를 정리하여 베리막스의 요인분석, 회귀분석, 군집분석등을 이용하여 분석하였다. 베리 막스의 요인분석으로 감성 형용사를 비슷한 척도끼리 묶어 .괘한 감성을 결정하는 요인, 자극의 강도를 결정하는 요인, 이외의 다른 고풍스럽거나 현대적인 요인등 3개 요인으로 grouping하였다. 향의 선호도를 결정하는데 중요한 감성척도에서는 피검자 성별에 따라 차이가 있음을 보여주었다. 남성의 경우 황홀하다, 여성적이다인데 반해 여성인 경우 재적하다, 친숙하다라는 감성 척도가 중요하게 작용하였다. 또한 각 향별로 군집 분류하여 향의 종류를 구분할 수 있었으며 또한 각 향별 선호도를 결정하는 감성 척도도 구해 보았다. 또한 향의 분류에 따른 감성 척도의 특징을 성별로 관찰한 결과 페르몬 향인 경우 essential oil과 달리 성별의 차이가 나타났다. 결론적으로 후각을 자극하는 향물질로 유발된 감성 측정을 해 본 결과 성별에 따라 선호도를 결정하는 감성요인의 차이를 알 수 있었으며 또한 essential oil에서는 성별 차이가 없는데 반해 페르몬 향의 경우 성별의 차이를 나타내었다.

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Depression after Traumatic Brain Injury (외상성 뇌 손상이후의 우울증)

  • Jung, Han Yong;Han, Sun Ho
    • Korean Journal of Biological Psychiatry
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    • v.6 no.1
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    • pp.21-29
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    • 1999
  • Traumatic Brain Injury(TBI) of any severity can result in broad and persisting biopsychosocial sequelae. Depression after TBI occur at a greater frequency than in the general population, with estimates approaching 25% to 50% for major depression, and 155 to 30% for dysthmia. Acute onset depressions are related to lesion location and may have their etiology in biological response of the injured brain, whereas delayed onset depressions may be mediated by psychosocial factors, suggesting psychological reactions as a possible mechanism. Anxious depressions are associated with right hemisphere lesions, whereas major depressions alone are associated with left dorsolateral frontal and left basal ganglia lesions. However, there is insufficient information to postulate a specific neuroanatomic model for TBI-related depression.

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The Effects of the Brain Education Meditation Program on Self-Regulated Learning Ability and the Academic Self-Efficacy of Elementary School Students (뇌교육명상프로그램이 초등학생의 자기조절학습능력과 학업적 자기효능감에 미치는 영향)

  • Kim, Dae-Myung
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.77-84
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    • 2016
  • This study is intended to identify the impacts the Brain Education Meditation Program have on elementary school students' self-regulated learning ability and the academic self-efficacy, This study aims to answer these three questions: First, is the Brain Education Meditation Program effective in improving self-regulated learning abilities of elementary school students? Second, is the Brain Education Meditation Program effective in improving the academic self-efficacy of elementary school students? Third, is there any positive correlation between the Self-Regulated learning ability and the academic self-efficacy of elementary school students? The data analysis results showed as follows: The Program thereby changes the self-regulated learning ability of the students. Second, it has improved the self-confidence, which is a sublevel factor of academic self-efficacy, of the elementary school students who participated in the Brain Education Meditation Program. Third, there exists the positive correlation between self-regulated learning ability and academic self-efficacy.

Reliability and Validity of the Korean Version of the Post-Traumatic Stress Disorder Checklist in Public Firefighters and Rescue Workers (소방공무원과 구조대원에서 한국어판 Post-Traumatic Stress Disorder Checklist의 신뢰도와 타당도)

  • Park, Shinwon;Jeong, Hyeonseok S.;Im, Jooyeon Jamie;Jeon, Yujin;Ma, Jiyoung;Choi, Yera;Ban, Soonhyun;Kim, Sungeun;Yu, Siyoung;Lee, Sunho;Jeon, Saerom;Kang, Ilhyang;Lee, Bora;Lee, Sooyeon;Son, Jihee;Lim, Jae-ho;Yoon, Sujung;Kim, Eui-Jung;Kim, Jieun E.;Lyoo, In Kyoon
    • Korean Journal of Biological Psychiatry
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    • v.23 no.1
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    • pp.29-36
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    • 2016
  • Objectives Firefighters and rescue workers are likely to be exposed to a variety of traumatic events; as such, they are vulnerable to the risk of post-traumatic stress disorder (PTSD). The psychometric properties of the Korean version of the PTSD Checklist (PCL), a widely used self-report screening tool for PTSD, were assessed in South Korean firefighters and rescue workers. Methods Data were collected via self-report questionnaires and semi-structured clinical interviews administered to 221 firefighters. Internal consistency, item-total correlation, one-week test-retest reliability, convergent validity, and divergent validity were examined. Content validity of the PCL was evaluated using factor analysis and receiver operating characteristic (ROC) analyses were used to estimate the optimal cutoff point and area under the curve. Results The PCL demonstrated excellent internal consistency (${\alpha}=0.97$), item-total correlation (r = 0.72-0.88), test-retest reliability (r = 0.95), and convergent and divergent validity. The total score of PCL was positively correlated with the number of traumatic events experienced (p < 0.001). Factor analysis revealed two theoretically congruent factors: re-experience/avoidance and numbing/hyperarousal. The optimal cutoff was 45 and the area under the ROC curve was 0.97. Conclusions The Korean version of the PCL may be a useful PTSD screening instrument for firefighters and rescue workers, further maximizing opportunities for accurate PTSD diagnosis and treatment.

The effect of the appropriateness of gustatory features in 'multi-sensory' product design on product evaluation : An fMRI study (공감각 제품디자인의 미각적 요소와 제품과의 적합성이 제품평가에 미치는 영향 : fMRI를 중심으로)

  • Sung, Young-Shin;Choi, Min-Jo
    • Science of Emotion and Sensibility
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    • v.14 no.2
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    • pp.235-244
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    • 2011
  • The purpose of this study is to investigate whether the appropriateness of gustatory features in product design affect product evaluation and accompanied response by using functional magnetic resonance imaging(fMRI). Through the pilot survey, we categorized the product designs into two groups based on the level of the appropriateness. The total of 40 product designs were selected as the experimental stimuli. 15 right-handed participants(mean age = 23.33, SD = 1.7) were scanned with 3T MRI machine(ISOL Tech, Oxford OR63). The experimental stimuli were passively presented inside the scanner. In post scanning session, participants were asked to measure their preference and buying intention to the product designs. The results show that both the preference and buying intention were significantly higher for the high appropriateness condition compared to those of low appropriateness designs. Caudate nucleus and putamen, areas related to the positive reward such as monetary acquisition showed greater activation in response to the designs of high appropriateness condition, compared to the low appropriateness designs.

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Psychological structure and ANS response by odor induced emotion (연령별 향 감성 구조 및 향 감성에 따른 자율신경계 반응)

  • 박미경;정희윤;이경화;최정인;이배환;손진훈
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • pp.127-133
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    • 2001
  • 본 연구는 향에 대한 연령별 감성 구조를 밝히고, 향 감성에 따른 자율신경계 반응을 밝히려는 것이다. 실험 참여자는 연령별(10대, 20대, 40대)로 24명씩, 총 72명이고 자극향은 cederwood, grapegruit, teebaum, peppermint, rose 향을 사용하였다. 향이 제시되는 동안 혈류량, 피부온도, 피부전기반응, 심전도 반응을 측정하였고, 향에 대한 주관적 감성을 측정하였다. 향에 의한 심리적 감성 구조는 심미성, 강도, 자연성, 개성성, 낭만성의 다섯 요인이 확인되었고, 연령별로 차이가 나타나지 않았다. 향 선호도를 예측하는 감성요인은 연령별로 차이가 났다. 감성적으로 "나쁜"향은 "좋은"향보다 교감신경계 활동에 의한 자율신경계 반응이 더 크게 일어났다.

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The structure of odor sensibility and physiological responses produced by odorants (향 감성 구조 및 생리 반응)

  • 박미경;이정미;최지연;이경화;이배환;손진훈
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • pp.32-37
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    • 2000
  • 본 연구는 향의 감성 구조를 밝히고, 향 선호도를 예측하는 감성요인을 규명하며, 향에 대한 자율 신경계 반응을 밝히는 것이 목적이다. 향에 대한 주관적인 감성을 측정하기 위하여, 25개의 감성 형용사로 구성된 향 감성 측정 척도를 개발하였다. 개발된 이 척도를 이용하여 lavender, lemon, rose, jasmin, peppermint의 다섯 가지 향에 대해 대학생 50명을 대상으로 향 감성 평가를 실시하였다 향에 대한 감성 구조는 심미성, 강도, 자연성, 여성성-남성성, 개성, 중량감의 여섯 요인으로 구성되었다. 향에 대한 자율 신경계 반응 측정은 대학생 20명을 대상으로 lavender, lemon, rose, jasmin, peppermint 향에 대해 실시하였다. 향에 대한 자율 신경계 반응 측정 결과, PPG 반응은 남녀 모두 lavender, lemon 향에서 유의미하게 감소하였다. 남자의 경우, PPG 반응은 rose, peppermint 향에서도 유의미하게 감소하였고, SKT 반응은 lavender, jasmin 항에 대해서 유의미하게 증가하였다.

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A research on feedback effect according to different sensory modality for attention recovery (집중력 회복을 위한 감각 모달리티 별 피드백에 대한 연구)

  • Hyun, Hye-Jung;Whang, Min-Cheol;Park, Jun-Seok;Lee, Yoon-Joung;Kim, Young-Joo;Kim, Jong-Hwa
    • 한국HCI학회:학술대회논문집
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    • pp.137-142
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    • 2007
  • 한정된 주의력 자원을 회복 시키기 위한 방법 중 피드백이 효과가 있는 것으로 보고되고 있다. 그러나 피드백의 구체적 내용에 대한 집중력 회복의 연구는 미미하다. 본 연구는 집중력을 회복할 수 있는 감각적 자극 중 정서적 피드백 간의 효과 차이를 분석 하였다. 집중력을 평가하기 위한 온라인 실험 시스템을 구축하고 시각, 청각, 촉각 피드백 자극을 제시하여 각각의 감각자극과 집중력 회복의 효과를 분석 하였다. 실험 참여자의 감각 피드백의 선호도에 따른 영향 요인을 알아보기 위하여 실험 후 주관적 설문을 실시하였다. 감각 피드백을 6명의 대학원생에게 일주일에 걸쳐 반복적으로 약200개의 자극을 제시하고 5회 이상 실험을 통하여 얻어진 30회 결과를 분석하였다. 결과적으로 피드백 별 수행 수준에서는 청각, 촉각, 시각 순으로 효과가 높았으며, 반응 시간에서는 촉각, 청각, 시각 순으로 효과적으로 나타났다.

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The Comparison of Susceptibility Changes in 1.5T and3.0T MRIs due to TE Change in Functional MRI (뇌 기능영상에서의 TE값의 변화에 따른 1.5T와 3.0T MRI의 자화율 변화 비교)

  • Kim, Tae;Choe, Bo-Young;Kim, Euy-Neyng;Suh, Tae-Suk;Lee, Heung-Kyu;Shinn, Kyung-Sub
    • Investigative Magnetic Resonance Imaging
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    • v.3 no.2
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    • pp.154-158
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    • 1999
  • Purpose : The purpose of this study was to find the optimum TE value for enhancing $T_2^{*}$ weighting effect and minimizing the SNR degradation and to compare the BOLD effects according to the changes of TE in 1.5T and 3.0T MRI systems. Materials and Methods : Healthy normal volunteers (eight males and two females with 24-38 years old) participated in this study. Each volunteer was asked to perform a simple finger-tapping task (sequential opposition of thumb to each of the other four fingers) with right hand with a mean frequency of about 2Hz. The stimulus was initially off for 3 images and was then alternatively switched on and off for 2 cycles of 6 images. Images were acquired on the 1.5T and 3.0T MRI with the FLASH (fast low angle shot) pulse sequence (TR : 100ms, FA : $20^{\circ}$, FOV : 230mm) that was used with 26, 36, 46, 56, 66, 76ms of TE times in 1.5T and 16, 26, 36, 46, 56, 66ms of TE in 3.0T MRI system. After the completion of scan, MR images were transferred into a PC and processed with a home-made analysis program based on the correlation coefficient method with the threshold value of 0.45. To search for the optimum TE value in fMRI, the difference between the activation and the rest by the susceptibility change for each TE was used in 1.5T and 3.0T respectively. In addition, the functional $T_2^{*}$ map was calculated to quantify susceptibility change. Results : The calculated optimum TE for fMRI was $61.89{\pm}2.68$ at 1.5T and $47.64{\pm}13.34$ at 3.0T. The maximum percentage of signal intensity change due to the susceptibility effect inactivation region was 3.36% at TE 66ms in 1.5T 10.05% at TE 46ms in 3.0T, respectively. The signal intensity change of 3.0T was about 3 times bigger than of 1.5T. The calculated optimum TE value was consistent with TE values which were obtained from the maximum signal change for each TE. Conclusion : In this study, the 3.0T MRI was clearly more sensitive, about three times bigger than the 1.5T in detecting the susceptibility due to the deoxyhemoglobin level change in the functional MR imaging. So the 3.0T fMRI I ore useful than 1.5T.

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