• Title, Summary, Keyword: 대사증후군

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Review of the Metabolic Syndrome (대사증후군의 개요)

  • Lee, Eun-Mi
    • Journal of Korean Life Insurance Medical Association
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    • v.26
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    • pp.13-20
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    • 2007
  • 대사증후군은 비만, 이상지혈증, 고혈압, 당뇨병이나 내당능 장애가 동반되어 나타나는 증후군이다. 근래 들어 우리나라도 점차 비만 인구가 증가함에 따라 대사증후군의 유병률이 빠르게 증가하는 추세를 보여. 대사증후군에 대한 간단한 개념 정리를 하였다. 먼저 대사증후군의 정의와 진단기준을 살펴보았다. 1998년 대사증후군을 명명하고 진안기준을 제시한 WHO 진단기준, NCEP-ATP III 진단기준, 인슐린 저항성 증후군의 진단기준을 살펴보고, 기타 인종에 따른 허리 둘레 기준 및 IDF 정의를 살펴 보았다. 또한 대사증후군과 관련된 여러 인자들도 다시 확인해보고, AHA/NHLBI 진단 기준도 살펴 보았다. 우리나라는 대부분 연구에서 NCEP-ATP III 기준을 적용하고 있는데, 그 내용은 복부 비만 허리둘레 남자 102cm 이상, 여자 88cm 이상, 중성 지방 150mg/dl 이상, HDL-콜레스테롤 남자 40mg/dl 미만, 여자 50mg/dl 미만, 혈압 130/85 mmHg 이상, 공복 혈당 110mg/dl 이상이다. 복부 비만의 경우는 2000년 제정된 WHO 서태평양 지역 기준인 남자 90cm, 여자 80cm 이상으로 적용하고 있다. 다음 치료의 기본 개념을 간단히 언급 하였는데, 가장 중요한 치료는 우선적으로 생활 습관의 개선을 꼽을 수 있으며, 기타 약물요법 및 인슐린 저항성 개선제 등이 있다. 우리나라 에서도 심혈관계 질환과 당뇨병이 점차 사망 원인의 우위를 차지 하고 있으므로 대사증후군을 초기에 진단하고 관리하는 노력이 매우 필요할 것으로 생각되며, 생명보험사도 대사증후군을 하나의 증후군으로 인식하여 대사증후군의 전반적인 이해가 필요할 것으로 생각된다.

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Prevalence of metabolic syndrome and health behaviors among Koreans (한국인에서 대사증후군의 유병상태와 보건의식행태)

  • Lee, Eun-Hui
    • Journal of Korea Association of Health Promotion
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    • v.3 no.2
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    • pp.199-218
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    • 2005
  • 이 연구는 우리나라 20세 이상 성인에서의 대사증후군 유병률을 파악하고 보건의식행태와 대사증후군간의 상관관계를 분석함으로써 대사증후군의 예방 및 치료를 위한 보건교육·건강증진 프로그램의 기초자료로 활용코자 시행되었다. 연구재료로 1998년 국민건강영양조사에 참여한 20세 이상 성인 24,469명 중 건강검진조사를 받았고 건강면접조사, 보건의식행태조사, 식생활조사에 응답한 7,854명의 조사결과를 활용하였으며, 2001년 미국에서 발포된 제 3차 콜레스테롤 관리지침(NCEP-ATP3)에서 제시된 대사증후군 진단기준 및 WH0 아시아/태평양지역 허리둘레를 기준으로 대사증후군 유병률을 분석하였다. 결과는 다음과 같다. 우리나라 20세이상 성인의 대사증후군 유병률은, NCEP-ATP3 기준에서 13.3%(남자 10.1%, 여자 16.0%), 아시아/태평양지역기준에서 19.8%(남자 16.7%, 여자 22.4%)로 아시아/태평양지역 기준에서, 남자보다는 여자에서 더 높았다. 대사증후군 진단항목 중복부비만, 저 HDL-콜레스테롤의 유병를은 여자에서, 고중성지방혈증, 공복시고혈당 유병률은 남자에서 더 높았고, 연령이 증가할수록 대사증후군의 유병률이 증가하였다. 또 대사증후근 진단할목의 보유경향은 ATP3진단기준에서 남자는 복부비만을 제외한 4개항목을 70%이상에서, 특히 고중성지방혈증은 95.0%에서 보유하였다 여자는 저HDL-콜레스테롤과 고중성지방혈증을 70%이상에서 보유하였다. 아시아/태평양 진단기준에서는 남자의 경우 고중성지방혈증을 88.0%에서, 여자의 경우 복부비만 및 저 HDL-콜레스테롤을 80%이상에서 보유하고 있었다. 대사증후군과 보건의식행태 간의 상관관계를 분석한 결과, 교육수준이 낮을수록, 결혼하지 않은 사람에 비해 결혼한 사람에서대사증후군 위험이 증가하였으며, BMI가 증가할수록 대사증후군 위험이 급격히 증가하였고, 고혈압·뇌졸중, 당뇨병 가족력이 있는 남자에서 대사증후군 위험이 증가하였다. 또 스스로 건강하지 않다고 생각하는 사람일수록 현재 흡연자의 PACK- YEAR가높을수록, 자주 술을 마실수록, )회 음주량이 많을수록, 과음빈도가 많을수록 대사증후근 위험이 증가하였으며, 알코올 의존 경향이 있는 경우에서도 유의한 결과를 보였다. 최근 1년간 체중이 감소 혹은 증가된 경우에서 유의한 결과를 보였으며, 체증감소정도가 클수록 대사증후군 위험이 증가하였다. 이상의 결과를 종합해 볼 때, 우리나라 성인의 대사증후군 유병률은 비교적 높으며 대사증후근의 발생에는 보건의식행태, 특히 음주 흡연비만 연령 교육수준 등이 밀접하게 관여한다고 할 수 있다. 그러나 앞으로 대사증후군의 예방을 위한 건강증진 프로그램의 기획 및 치료방침 수립을 위해서는 우리 나라대사증후군의 유병에 영향을 미치는 진단기준항목 및 관련요인의 상호 연관성, 우리나라에 적합한 진단기준 설정 등에 대한 지속적이고 깊이 있는 연구가 이루어져야 할 것이다.

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건강의 새로운 화두, 대사증후군- 대사증후군을 진단하는 기준들

  • Kim, In-Ju
    • The Monthly Diabetes
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    • pp.8-10
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    • 2005
  • 대사증후군이란 비만, 당대사이상, 고혈압 및 이상지질혈증과 같은 다양한 대사이상이 한 개인에게 중복되어 나타나는 상태를 지칭하는 것이다. 그러므로 대사증후군도 생활 습관병 중의 하나라고 생각할 수 있다. 대사증후군을 막을 수 있는 가장 경제적이면서도 효육적인 방법으로는 적절한 운동과 식사요법이라는 건강한 생활습관을 유지하여 적정한 체중을 유지하는 기초적인 건강수칙을 실천하는 것이 무엇보다 중요하다.

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A Study on the Characteristics of Nutrient Intake in Metabolic Syndrome Subjects (대사증후군 대상자의 영양소 섭취 특성에 관한 연구)

  • Yoo, Hyun-Jung;Kim, Yang-Ha
    • Journal of Nutrition and Health
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    • v.41 no.6
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    • pp.510-517
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    • 2008
  • This study was conducted to investigate the prevalence of metabolic syndrome(MS) and characteristics of nutrient intake in MS subjects by gender and age. The subjects were 957(447 men and 510 women) who visited medical center for regular medical check-up. The diagnosis of MS subjects was adapted from NCEP-ATPIII with blood glucose, cholesterol, triglycerides, and blood pressure and Aisa-Pacific definition with waist-circumference. Anthropometric and biochemical measurements were practiced, then the nutrient intake analysis was assessed through the 24-hour recall method. The MS prevalence of all subjects was 10.3% in average -17% in men and 4.5% in women, respectively. The energy intake in MS group was 2,047.1 kcal and 1,699.5 kcal for normal group, showing significantly higher in MS compared to normal subjects. For intakes of animal fat, cholesterol, and sodium, MS group were significantly higher than normal group. In respect of gender, men subjects of MS group showed significantly higher nutrient intakes than normal group for energy, fat, and cholesterol. Women subjects of MS group showed higher intakes for energy, carbohydrate, and protein. For 30s, MS group showed higher intakes of energy, animal fat, and cholesterol than normal group. Fat and cholesterol for 40s and energy, carbohydrate, vegetable fat for 50s, MS group showed significantly higher intakes than normal group. In summary, MS group showed higher intakes of energy, animal fat, cholesterol, and sodium than normal group.

The study on risk factors for diagnosis of metabolic syndrome and odds ratio using multifactor dimensionality reduction method (다중인자 차원 축소 방법에 의한 대사증후군의 위험도 분석과 오즈비)

  • Jin, Mi-Hyun;Lee, Jea-Young
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.4
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    • pp.867-876
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    • 2013
  • Metabolic syndrome has been known as a major factor of cardiovascular disease. Several metabolic disorders, particularly chronic disease is complex, and from individuals that appear in our country, the prevalence of the metabolic syndrome is increasing gradually. Therefore, this study, using a multi-factor dimensionality reduction method, checks the major single risk factor of metabolic syndrome and suggests a new diagnosis results of metabolic syndrome. Data of 3990 adults who responded to all the questionnaires of health interview are used from the database of the 5th Korea national health and nutrition examination survey conducted in 2010. As the result, the most dangerous single risk factor for metabolic syndrome was waist circumference and the most dangerous combination factors were waist circumference, triglyceride, and hypertension. This is the result of a new diagnosis of the metabolic syndrome. Especially, waist circumference, low HDL-cholesterol and hypertension were the most dangerous combination for male. In particular, the combination of waist circumference, triglyceride and diabetes was dangerous for obese people.

Association Metabolic Syndrome with Sarcopenia in Korean Stroke Patients : Korean National Health and Nutrition Examination Survey Data(2008-2011) (뇌졸중 유병자의 대사증후군과 근감소증의 관련성: 국민건강조사(2008년-2011년)자료를 근거로)

  • Choi, Sook-Hee;Kim, Yun-Hee
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.165-174
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    • 2018
  • The purpose of this study was to examine the association metabolic syndrome with sarcopenia in Korean stroke patients. We used the Korean National Health and Nutrition Examination Survey data from 2008 to 2011 and enrolled a total of 316 stroke patients older than 40 years. Data were analyzed by Rao-Scott ${\chi}^2-test$, generalized linear model and composite sample multiple logistic regression. The prevalence of sarcopenia was 47.3% in men and 46.3% in women. The prevalence of metabolic syndrome was 50.3% in men and 73.6% in women. After adjusting for age, smoking status, alcohol consumption, exercise, education, income, sroke sequla and stroke duration, men with sarcopenia had increased risk of metabolic syndrome (95% CI: 2.454-18.482, p<.001). This finding can be used to develop evidence-based health promotion program to prevent stroke reccurance for stroke patients.

The change patterns of the Clustering of metabolic syndrome (대사증후군 구성요인의 군집별 변화 양상)

  • Kim, Young-Ran;Cheon, Hae-Kyung;Lee, Tae-Yong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.526-537
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    • 2016
  • Objective: This study examined the changes in the clustering of metabolic syndrome, and examined the distribution of a combination of clustering. Methods: The study was performed with the data from the same 1,900 people who had a medical checkup at a health clinic twice from 2009 to 2013. The subjects were divided into two groups of metabolic syndrome and non-metabolic syndrome (normal group) and examined according to the periodic changes. The related factors were examined with a cohort study. Results: The order affecting the prevalence of metabolic syndrome by the combination of metabolic syndrome constituent factors was two combinations (TG+HDL), three combinations (WC+TG+HDL), and four combination (WC+TG+HDL+BP). Conclusions: To manage these factors, public health programs will be needed and the methods to prevent metabolic syndrome should be promoted. In addition, more study on the risk factors of metabolic syndrome will be needed.

The Prevalence of Metabolic Syndrome and Related Risk Factors Based on the KNHANES V 2010 (제 5기 국민건강영양조사로 추정한 한국 성인의 대사증후군 유병률과 관련 요인)

  • Park, Eunok;Choi, Su Jung;Lee, Hyo Young
    • Journal of agricultural medicine and community health
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    • v.38 no.1
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    • pp.1-13
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    • 2013
  • Objectives: This study is to investigate the prevalence and related factors of metabolic syndrome among Korean adults aged 20 years and above. Methods: From the database of the $5^{th}$ Korea National Health and Nutrition Examination Survey (KNHANES V) conducted in 2010, data of 5,670 adults who responded to all the questionnaires of health interview and had metabolic syndrome in the health examination were included in this analysis. SAS 9.2 was used for statistical analysis with complex sample survey modules and commands. Results: The prevalence rate of metabolic syndrome based on the criteria proposed by International Diabetes Federation (IDF) was 18.8%. The prevalence of metabolic syndrome in each group was: 20.7% of women, 43.1% among elderly over 70 years old, 40.6% of the divorced or the separated, 27.6% of recipients of economic support from the government, 23.6% of people who had alcohol dependency problem, and 43.7% of overweight or obese adults. Independent risk factors based on the multiple logistic regression analysis revealed that prevalence of metabolic syndrome was associated with female (odds ratio 1.59 [95% confidence interval 1.20-2.11]), age (50s 3.95 [2.11-7.37], 60s 5.62 [2.98-10.61], 70s 10.56 [5.25-21.25]), high school education (0.52 [0.37-0.74]), clerk occupation (2.14 [1.27-3.60]), divorced marital status (1.72 [1.15-2.59]), alcohol dependency (1.86 [1.16-2.98]), higher BMI (14.08 [10.60-18.70]). Conclusions: The metabolic syndrome is prevalent among Korean adult population according to IDF criteria. Several demographic characteristics and potentially modifiable factors are associated with metabolic syndrome. Identification of this high-risk group and management of these modifiable factors are warranted to reduce the prevalence of metabolic syndrome.

Predictors of Metabolic Syndrome in Chronic Schizophrenic Patients Followed for 5 Years(2011-2016) (5년 동안 추적한 만성 조현병 환자에서 대사증후군의 예측인자)

  • Joe, Jae-Gil;Yoon, Bo-Hyun;Jeon, Bong-Hee;Park, Su-Hee;Song, Je-Heon;Jeong, Ha-Ran;Hong, Kye Hyun
    • Korean Journal of Psychosomatic Medicine
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    • v.24 no.2
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    • pp.217-226
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    • 2016
  • Objectives : To investigate changes in, and predictors of, metabolic syndrome(MetS) status over a 5-year period in chronic schizophrenic patients and to identify factors associated with the prevention of or recovery from MetS. Methods : In total, 107 patients, all of whom provided written informed consent, were followed from 2011 to 2016 at Naju National Hospital for this study. MetS was defined according to the revised National Cholesterol Education Program-Adult Treatment Panel III guidelines. Results : During follow-up period, 22(20.5%) patients were newly diagnosed to MetS, 14(13.1%) were disappeared, 77(66.4%) were not changed[MetS : 34(31.8%), No MetS 37(34.6%)]. Common significant factors in the two changed groups were triglyceride and waist circumference, not dose and type of antipsychotic medication. Multiple logistic regression analysis revealed that female gender(odds ratio[OR]=2.846, 95% confidence interval[CI] : 1.020-7.942), attending two or more outpatient visits per month(OR=3.155, 95% CI : 1.188-8.379) and taking antidepressant medication(OR=3.991, 95% CI : 1.048-15.205) were significantly associated with MetS after controlling for other confounding variables. Type and dose of antipsychotic medication were not significantly associated with MetS. Conclusions : Triglyceride and waist circumference were important manageable indicator of MetS. Adoption of a healthy lifestyle is more important than adjusting the dose or type of antipsychotic medication in the treatment of chronic schizophrenia patients with MetS.

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Analyzing the effects of emotional states on the metabolic syndrome risk factors in Korean adolescents (감성요인이 국내 청소년 대사증후군 위험요인에 미치는 영향)

  • Jeon, Hyeon Gyu;Won, Jong Yoon;Lee, Kun Chang
    • Journal of Digital Convergence
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    • v.17 no.10
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    • pp.359-372
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    • 2019
  • Metabolic syndrome is deeply related with risks of chronic disease and mortality. Furthermore, the metabolic syndrome disorder in childhood and adolescence usually tends to lead to a number of cardiovascular disease in the stage of adulthood. In this sense, metabolic syndrome needs to be investigated seriously. The purpose of this study is therefore to prove the relationship between dietary habits(high carbohydrate, high calorie) and metabolic syndrome among adolescents. We also aim to clarify the relationship between emotional factors perceived by adolescents and metabolic syndrome. Our empirical results based on KNHANES dataset significantly demonstrates that the HDL-cholesterol is a decisive factor for the diagnosis of metabolic syndrome disorder. Additionally, emotional experience factors such as stress also show significant effects in difference of adolescents' metabolic syndrome.