This study investigates the effects of parent-adolescent communication, emotional intelligence and parentification on the psychological well-being of adolescents. Participants were 712 middle and high school students from Seoul. The collected data were analyzed through a Cronbach's $\alpha$, two-way ANOVA, Pearson's correlation and stepwise multiple regression. The results are as follows: 1) While parent-adolescent communication, parentification, and psychological well-being differed by grade, emotional intelligence did not differ by grade. 2) Father-adolescent communication, regulation of emotion, expression of emotion, practice of emotion, recognition of emotion and mother-adolescent communication were significant predictors of the psychological well-being of middle school students. 3) The recognition of emotion, father-adolescent communication, practice of emotion, regulation of emotion, and mother-adolescent communication were significant predictors of the psychological well-being of high school students. 4) Emotional intelligence played a partially mediating role in the relationship between parent-adolescent communication and psychological well-being.