• Title, Summary, Keyword: Alcohol level

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Gender Differences in the Relationship between Alcohol Use Behaviors and Metabolic Syndrome - Korean National Health and Nutrition Examination Survey (KNHANES) V 2010 - (성별에 따른 알코올사용행태와 대사증후군과의 관계 - 제5기 2010년 국민건강영양조사 자료를 이용하여 -)

  • Ryu, Ji Young;Kim, Dae-Hwan
    • Korean Journal of Health Education and Promotion
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    • v.30 no.1
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    • pp.83-93
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    • 2013
  • Objectives: The objective of this study was to assess the gender differences in the relationship between alcohol use behaviors and the risk of metabolic syndrome among Korean adult population. Methods: Data from the Korean National Health and Nutrition Examination Survey (5th, 2010) was analyzed. Using the Alcohol Use Disorders Identification Test, subjects were classified into 4 groups including non-drinking, low-risk drinking, medium-level alcohol problem, and high-level alcohol problem group. Metabolic syndrome and its components were compared among the alcohol behavior groups by gender. Results: The odds ratio vs. non-drinking group for metabolic syndrome was significantly higher in male medium and high-level alcohol problem group. In female, high-level alcohol problem group showed significantly higher odds ratio for metabolic syndrome. Blood pressure and HDL-cholesterol were likely to be higher with the excessive drinking behaviors in both men and woman. Triglyceride level in men was significantly higher in the medium and high-level alcohol problem group than non-drinking group. Although fasting glucose level did not show differences among drinking groups, the odd ratios vs. non-drinking group for the hyperglycemia (${\geq}$ 100mg/dl) were significantly higher in female drinking groups. Conclusions: Problematic alcohol drinking is likely to increase the risk of metabolic syndrome in Korean adults.

The Alteration of Carbohydrate-Deficient Transferrin and Nerve Growth Factor in the Patients with Alcohol Dependence (알코올 의존 환자에서 탄수화물결핍 트랜스페린과 신경성장인자의 변화)

  • Jeon, Chan-Min;Park, Boung-Yang;Byun, Jung-Hyun;Lee, Boung-Chul;Ham, Byung-Joo;Hur, Mina;Choi, Ihn-Geun
    • Korean Journal of Biological Psychiatry
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    • v.14 no.3
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    • pp.161-166
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    • 2007
  • Objectives:Recent studies have raised the possibility that nerve growth factor(NGF) is abnormally regulated in the central nervous system(CNS) of animal models with alcohol dependence. The possible alteration of NGF by prolonged alcohol intake may play an important role in alcohol-induced neurotoxicity. Carbohydrate-deficient transferrin(CDT) is regarded as a reliable biological marker of alcohol dependence. The goal of this study was to estimate the changes of %CDT and serum NGF level according to the duration of alcohol abstinence, and to identify whether %CDT level is associated with the serum NGF level in the patients with alcohol dependence. Methods:The subjects were 24 patients with alcohol dependence. We used the Axis-Shield ASA to measure the %CDT level and the enzyme-linked immunosorbent assay(ELISA) to measure the serum NGF level. %CDT and NGF levels were measured immediately after the admission and at 2 weeks after the admission. Results:Decreased %CDT were observed during the period of 2 weeks after the admission. NGF level was not significantly different after 2 weeks. The NGF levels were not correlated with %CDT. The possibility of %CDT as a predictor of alcohol-induced neurotoxicity was not confirmed. Conclusion:Serum NGF levels is not a reliable indicator of abstinence state in the patients with alcohol dependence. Further studies are needed to evaluate the relation between two indicators in regard to hematological and neurological changes in alcohol dependence.

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Effects of Water Extracts in fruits of Omija (Schizandra chinensis Baillon) on Alcohol Metabolism (오미자 열매의 물추출물이 알콜대사에 미치는 효과)

  • Lee, Joung-Sook;Lee, Sung-Woo
    • Journal of the Korean Society of Food Culture
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    • v.5 no.2
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    • pp.259-263
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    • 1990
  • To assess the effects of water extracts in fruits of Omija (Schizandra chinensis Baillon) on alcohol metabolism, rats were orally administrated with alcohol (25% alcohol, 0.75g/200g B.W., 40% alcohol, 0.8g/200g B.W.). The level of metabolites and enzyme activities of the serum and liver were unchanged by the 25% ethanol or 40% ethanol treatment with acute orally administration. Blood alcohol level was markdely decreased by the treatment with water extracts in fruits of Omija. The serum level of Urea nitrogen, Free fatty acid, GPT and LDH were tended to decreased, level of GOT was unchanged. Contents of hepatic microsomal protein, glycogen, pyruvate in the liver were increased by water extracts in fruits of Omija. In conclusion, the present study clearly demonstrates that water extract in fruits of Omija promotes the overall metabolism and detoxication of alcohol.

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Effect of Ginseng on the Alcohol Metabolism in Alcohol Treated Rat (알톨 대사에 미치는 인삼의 영향)

  • Huh, Keun;Choi, Chong-Won
    • YAKHAK HOEJI
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    • v.28 no.1
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    • pp.49-51
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    • 1984
  • After pretreatment with ginseng followed by induction of acute intoxication of alcohol, the activities of alcohol dehydrogenase (ADH), microsomal ethanol-oxidizing system (MEOS) and aldehyde dehydrogenase(Ald DH) increased respectively compared to the groups treated with alcohol alone. In case that ginseng was given to rats fed with 5% alcohol instead of water for 60 days, the activities of ADH and MEOS increased compared to the groups treated. On the contrary, the activity of Ald DH in mitochondrial fraction decreased to an extent of about 35% in chronic alcoholism, but after pretreatment of ginseng the activity was restored to the control level. On the other hand, the catalase activity was not significantly affected by either treatment. Ginseng butanol fraction significantly increased the serum isocitrate dehydrogenase activity which is inhibited by alcohol-treated in rat. Alcohol-induced lactate dehydrogenase activity was decreased to control level in liver by ginseng treatment. And the serum level of lactic acid also decreased by ginseng treatment in alcohol-intoxicated rat. Ginseng butanol fraction markedly decreased the xanthine oxidase activity in the ethanol-treated rat liver. It was also observed that ginseng reduced the blood concentration of uric acid on experimentally reduced hyperuricemia by alcohol treatment. Uricase activity was not affected by either treatment. Ginseng butanol fraction decreased the hepatic aniline hydroxylase activity which was induced by alcohol-treated rat. These results suggest that the treatment with ginseng can be promoted the recovery from alcohol intoxication and some therapeutic effect on alcoholinduced metabolic disease.

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Family Support, Alcohol Consumption and Drinking Motives in Patients with Liver Cirrhosis (간경변증 환자의 가족지지, 음주정도 및 음주동기)

  • Kim, Nam Young;Kim, Ok Soo
    • Korean Journal of Adult Nursing
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    • v.19 no.2
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    • pp.295-304
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    • 2007
  • Purpose: The purpose of this study were to investigate the level of family support, alcohol consumption and drinking motives in patients with liver cirrhosis and to examine the relationships among those variables. Methods: The subjects consisted of 60 patients with liver cirrhosis. Family support scale, Q-F methods and Drinking Motives Questionnaire were used to measure the level of family support, alcohol consumption and drinking motives. Results: The level of family support was 43.62. Prevalence of drinking was 90% and 43.3% were currently heavy drinkers. Alcohol consumption was related to sex and education. There were positive low relationships between the level of enhancement motive, coping motive, social motive, and Q-F Index. Conclusion: Alcohol drinking is a serious health problem in patients with liver cirrhosis. It is necessary to have an educational approach for controlling drinking and family support.

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A Study on Alcohol Expectancy of Elementary Schoolchild (초등학생들의 음주기대에 관한 연구)

  • Lim, Mi-Suk;Park, Young-Soo
    • The Journal of Korean Society for School & Community Health Education
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    • v.3
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    • pp.15-33
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    • 2002
  • Researchers' common findings is that there are positive or negative effect of alcohol expectancy on drinking behavior. Therefore we would effectively prevent troublesome drinking of the youth and university students by inquiring and controlling critical factors affecting alcohol expectancy. The purposes of this thesis are, first, to empirically test factors affecting the alcohol expectancy level of elementary schoolchild(potential drinker).; second, to suggest the necessity for development of pre-alcohol prevention programs. On the basis of previous research, eighteen factors included in four categories(general characters, environmental characters, alcohol knowledge, drinking experience) affecting alcohol expectancy level were found out. 623 subjects used in this study were drawn from 8 elementary schools in Daegu, Korea. The empirical results suggested that the alcohol expectancy level of elementary schoolchildren was negative in general. And it was proved that 9 factors were significantly correlated with alcohol expectancy level. To put it concretely(see Fig.), (1) It was proved that schoolchildren with bad environment(live in oneself, displeased drinking feeling) rather than good environment(live with parents, nice drinking feeling) for drinking had more negative alcohol expectancy. (2) Korean traditional culture that partakes of sacrificial food and drink have an influence on the first drinking of most elementary schoolchildren. And it was proved that schoolchildren with this drinking experience rather than any other motives had less negative alcohol expectancy. (3) It was proved that schoolchildren adapting themselves rather than being difficult in school life had more negative alcohol expectancy. And the more knowledge about alcohol or drinking schoolchildren had, the more they had negative alcohol expectancy (4) It was proved that schoolchildren having drinking experience or drinking at present rather than having no drinking experience or not-drinking at present had less negative alcohol expectancy. (5) It was proved that schoolchildren having strong drinking intention rather than having weak or no drinking intention in the future had more positive alcohol expectancy. Based on previous results, guideline for development of pre-alcohol prevention programs can be represented: discriminated programs development on educatee, drinking education programs development increasing the power of self-control about alcohol and drinking, social education or continuing education programs development on drinking, open preschool education to substantially prevent drinking or alcoholism etc. The findings, however, should be interpreted with caution, because this study has several limitations in measurement and sampling as follows. First, selection bias because of limited selection of sampling. It is because the subjects are drawn from only 8 elementary schools in Daegu. Second, less refined measurement ; Therefore, it is necessary to develop more detailed measures on alcohol knowledge, alcohol expectancy level especially. Further researches should be suggested and encouraged with more refined methodologies.

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Effects of Chungganhaeju-tang(Qingganjiejiu-tang) on Alcohol Metabolism and Alcoholic Liver Damages (청간해주탕이 알코올대사 및 손상간에 미치는 영향)

  • 곽미애;이장훈;우홍정
    • The Journal of Korean Medicine
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    • v.21 no.1
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    • pp.68-76
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    • 2000
  • Objectives: This experiment was conducted to verify the effects of Chungganhaeju-tang(Qingganjiejiu-tang) on the alcohol metabolism and liver functions, by measuring the activity levels of ADH and ALDH, as well as glucose, triglyceride, and BUN. Damage of the liver cells caused by alcohol was determined through the examination of serum levels of AST, ALT, ALP, LDH, and uric acid. Methods: Sprague-Dawley rats were used in this experiment and the rats were divided into control and experiment groups. Chungganhaeju-tang(Qingganjiejiu-tang) extract was orally administered in the experiment group for three weeks. Each group was further classified into two sub-groups, and control group's blood was taken without oral ingestion of alcohol, while the experiment group' s blood was withdrawn after ingestion of alcohol. Evaluation of damage level was done considering the presence of extract and alcohol. Results: In this experiment, Chungganhaeju-tang(Qingganjiejiu-tang) significantly suppressed the activity of ADH which is a precursor enzyme of acetaldehyde, but didn't cause significant changes in the activity of ALDH which is a catabolic enzyme. Decreased glucose level due to alcohol consumption was recovered back to the normal level and increased levels of triglyceride, BUN, AST, ALT, ALP, LDH, and uric acid were significantly reduced. Conclusions: These experiment results suggest that Chungganhaeju-tang(Qingganjiejiu-tang) inhibits the formation of acetaldehyde in the metabolism of alcohol, and affects the recovery of weakened liver functions due to alcohol.

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Sex-specific relationships between alcohol consumption and vitamin D levels: The Korea National Health and Nutrition Examination Survey 2009

  • Lee, Ka-Young
    • Nutrition Research and Practice
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    • v.6 no.1
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    • pp.86-90
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    • 2012
  • This study assessed the association between vitamin D sufficiency (serum 25(OH)D ${\geq}30ng/mL$) and alcohol consumption using data from the Korea National Health and Nutrition Examination Survey conducted in 2009. The following characteristics were obtained in 7,010 Korean participants ${\geq}19$-years-of-age: serum 25(OH)D level, alcohol consumption (drinking frequency, drinking number of alcoholic beverages on a typical occasion, average daily-alcohol intake), and potential confounders (age, residence, housing status, occupation, total fat and lean mass, smoking, physical activity, history of liver diseases, liver function, and daily intake of energy, protein, and calcium). After adjusting for confounders, vitamin D sufficiency in men was significantly associated with drinking frequency, number of alcoholic drinks consumed, and average daily alcohol intake; odds ratio of 1.21-1.72, 2.17-3.04, and 2.27-3.09, respectively. Increase in the three alcohol drinking-related behaviors was also linearly associated with increase in serum 25(OH)D level in men. By comparison, there was no significant association between alcohol intake and serum 25(OH)D level in women. The positive association between vitamin D sufficiency and alcohol consumption was evident only in Korean men.

Effects of Policy and Environmental Characteristics of University on Drinking Problems among University Students (대학교 음주관련 정책 환경이 대학생 음주문제에 미친 영향)

  • Kim, Kwang-Kee;JeKarl, Jung;Lee, Ki-Il;Park, Jung-Eun
    • Korean Journal of Health Education and Promotion
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    • v.29 no.2
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    • pp.83-91
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    • 2012
  • Objectives: This study is to examine that drinking problems among university students were accounted for not only by student's individual characteristics but alcohol policy and environmental characteristics of the university in which students were enrolled. Method: Secondary data analysis was employed in which variables under study were derived from a raw data of a nationwide representative sample in 2009. Raw data under analysis included 3,665 students from 63 universities across Korea. Organizational and environmental characteristics of the university were collected from university administrators while individual characteristics and drinking behavior from the students in using self-administrated questionnaire. Multilevel regression analyses were employed to describe alcohol policy effects on students's drinking problems measured by AUDIT by using HLM7.0. Results: ICCs indicate that variation in drinking problem depends on alcohol policy of university. Multilevel regression models identified statistically significant factors in explaining variance of drinking problems. Group means on drinking problem are affected by indicators representing alcohol policy with level of drinking problem of student being decreased in accordance to level of availability of alcohol on campus. Conclusions: It is concluded that drinking problems among university students were associated with both individual characteristics and alcohol policy of the university they enrolled. This study supports policy belief that interventions at environmental as well as individual level are required to prevent drinking problem among university students.

A Study on the relationship among alcohol levels, and impact of event, occupational stress, and distress disclosure among fire officials (소방공무원의 음주수준과 사건충격, 직무스트레스, 자기노출 간의 관계 연구)

  • Sim, Gyu-Sik;Kim, Yeon-Jung
    • The Korean Journal of Emergency Medical Services
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    • v.23 no.1
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    • pp.135-146
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    • 2019
  • Purpose: The aims of this study were to identify the relationships among alcohol level, impact of event, occupational stress, and distress disclosure and to determine the influences on alcohol level among fire officials. Methods: Participants in this cross-sectional, descriptive study were 241 fire officials. Data were collected from June 2018 to July 2018 using self-reported questionnaires and were analyzed using IBM SPSS 22.0 software (IBM, Armonk, NY, USA). Results: The results revealed significant positive relationships between alcohol level and impact of event, and impact of event and occupational stress, and a negative relationships between occupational stress and distress disclosure. Regression analysis revealed that alcohol level accounted for 9.2% of the variance by gender, and impact of event(e.g., sleep problems and emotional numbness). Conclusion: These findings provide information that can be used in the development of mental health promotion programs for fire officials.