• Title, Summary, Keyword: Call-Exner bodies

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Granulosa cell tumor in a sow (돼지의 과립막세포 종양)

  • Kim, Hyeong-Seok;Kang, Sang-Chul;Jung, Ji-YouI;Kim, Hyun-Sup;Kim, Dae-Yong;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.48 no.3
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    • pp.323-326
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    • 2008
  • A two-year-old mixed breed sow was requested to the Veterinary Pathology Laboratory of Cheju National University with a clinical signs of severe abdominal pain and sudden death. Grossly, there was severe hemorrhage in abdominal cavity. Most of internal parenchymas and subcutaneous muscle showed severe pale discoloration. Both ovaries were enlarged with oval to round protruding multilobular masses and dark red in color. And they were firm and contained multiple small cysts in their cut surface. Histopathologically, numerous neoplastic granulosa cells had spherical-to-oval, hyperchromatic nuclei and scant eosinophilic cytoplasms were distributed with follicular pattern in ovarian masses. And the typical Call-Exner bodies, distinctive microcavityies, were observed in the center of small neoplastic follicles. Based on the gross and histopathologic findings, this case was diagnosed as granulosa cell tumor. In our best knowledge, this is believed to be the first report of granulosa cell tumor in a sow in Korea.