• Title/Summary/Keyword: Dystonia

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Case Study of a Patient with Dystonia Due to Dystonic Cerebral Palsy Treated with Traditional Korean Medicine (뇌성마비로 인한 근육긴장이상(Dystonia) 치험 1례)

  • Lee, Mi-rim;Kim, Su-bin;Woo, Ji-myung;Kang, Ah-reum;Cho, Ki-ho;Moon, Sang-kwan;Jung, Woo-sang
    • The Journal of Internal Korean Medicine
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    • v.37 no.2
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    • pp.257-264
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    • 2016
  • Objectives: This study presents a case of a 37-year-old Korean male with dystonia due to dystonic cerebral palsy who was treated with herbal medicine (Ukgan-san), acupuncture, and cupping treatment.Method: We executed the unified dystonia rating scale (UDRS) and the Toronto western spasmodic torticollis rating scale (TWSTRS) to evaluate dystonia.Results: The patient’s dystonia showed improvement after the administration of traditional Korean medical treatments.Conclusion: Traditional Korean medical treatment may be effective in treating dystonia due to dystonic cerebral palsy.

Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia

  • Jin, Seon Tak;Lee, Myung Ki;Ghang, Ju Young;Jeon, Seong Man
    • Journal of Korean Neurosurgical Society
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    • v.52 no.3
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    • pp.261-263
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    • 2012
  • The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical experience of bilateral GPi-DBS under general anesthesia by using microelectrode recording in a 7-year-old girl with early-onset DYT1 generalized dystonia. Excellent improvement of her dystonia without neurological complications was achieved. This case report demonstrates that GPi-DBS is an effective and safe method for the treatment of medically refractory early-onset DYT1 generalized dystonia in children.

A Clinical Case Report on Treatments of Cervical Dystonia (경련성(痙攣性) 사경증(斜頸症) 환자(患者) 치험(治驗) 1예(例) 보고)

  • Byun, Sung-Bum;Yun, Jong-Min;Moon, Byung-Soon
    • The Journal of Internal Korean Medicine
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    • v.34 no.4
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    • pp.456-465
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    • 2013
  • Objectives : A case of cervical dystonia improved after Korean medical treatments by using measurements of Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), and Cervical Dystonia Impact Profile (CDIP-58) to evaluate the changes of symptoms. Methods : Korean medical treatments for relieving symptoms of cervical dystonia including acupuncture, herb medication, cupping therapy, and physical therapy were performed. To evaluate the effect of the treatments, TWSTRS and CDIP-58 were used. Results : TWSTRS decreased from 55 to 24.5 and CDIP-58 also decreased from 79.3 to 36.2. Conclusions : This report suggests that Korean medical treatments can be effectively used for patients with cervical dystonia. Further clinical studies are needed to verify the findings.

A Case Report of a Patient with Cranial Dystonia Diagnosed as Meige Syndrome (메이그증후군으로 진단받은 안면 근육 긴장 이상 환자 증례 보고 1례)

  • Park, Song-won;Kim, Youngji;Song, Jooyeon;Lee, Chan-sol;Hong, Seungcheol;Oh, Ji-hye;Jung, Ji-chun
    • The Journal of Internal Korean Medicine
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    • v.39 no.5
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    • pp.886-894
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    • 2018
  • Objective: Despite being the most common cause of cranial dystonia, Meige syndrome remains a rare clinical entity. It is characterized by blepharospasm and orofacial dystonia. This case study reports on the use of traditional Korean medicine for a patient who suffered from blepharospasm and oromandibular dystonia suspected to be the result of Meige syndrome. Methods: A patient was given a series of Korean medicine therapy treatments, including administration of the herbal medicine Gamiguibi-tang-gamibang, acupuncture, and cupping, over a 19 day hospitalization period. We measured the state and progress of this case using the numeric rating scale and dystonia frequency. Results: A decrease in subjective symptoms and reduction in the frequency of oromandibular dystonia was observed after Korean medicine therapy treatments. Conclusion: This case is useful for describing herbal medicine treatment for Meige syndrome, and further case reports and studies will be needed in the future.

Case Report : Botulinum Toxin Treatment in Oromandibular Dystonia (보툴리눔 톡신을 이용한 구강하악 근긴장이상증의 치료 증례)

  • Ryu, Ji-Won;Hong, Seong-Ju;Bae, Kook-Jin;Yoon, Chang-Lyuk;Ahn, Jong-Mo
    • Journal of Oral Medicine and Pain
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    • v.34 no.4
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    • pp.421-427
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    • 2009
  • Oromandibular dystonia is a focal neurological movement disorder characterized by involuntary sustained and often painful muscle contraction, usually producing repetitive movements or abnormal positions of the mouth, jaw and.or tongue. Patients suffering from oromandibular dystonia often experience difficulties in chewing, swallowing and speaking, resulting from the impairment of mandibular movements. At present there is no etiologic treatment for oromandibular dystonia, because the pathophysiology of primary and focal dystonia is still incompletely understood. Many treatments such as medication, behavioral therapy, surgery are suggested to decrease the involuntary movements. But these success rates are relatively low and they have a lot of complications. many studies suggested that chemodenervation with botulinum toxin is the most effective treatment for oromandibular dystonia. We reported the 2 cases which were treated oromandibular dystonia with botulinum toxin and reviewed the orofacial movement disorders(especially oromandibular dystonia) and botulinum toxin treatment for oromanfibular dystonia.

Peripheral Post-traumatic Cervical Dystonia Treated by Miniscalpel-Acupuncture: A Case Report (말초성 외상후 경부 근긴장이상증에 대한 도침치료: 증례 보고)

  • Yoon, Sang-Hoon;Jo, Hee-Guen;Kwon, Min-Goo;Song, Min-Yeong
    • Journal of Korean Medicine Rehabilitation
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    • v.28 no.1
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    • pp.161-166
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    • 2018
  • This report describes the miniscalpel-acupuncture treatment of a 68-yr-old woman who had abnormal posture and involuntary dystonic movements of the head and neck. She suffered muscle contracture associated symptoms after she fell injured in 2014. Her neck had abnormal posture findings due to muscle tension. The spasms gradually worsened and did not respond to botulinum toxin injections. Involuntary dystonic movements may be due to peripheral post-traumatic cervical dystonia. Outcomes support cervical dystonia may be managed effectively with miniscalpel-acupuncture. Further research is recommended.

A Case Report of Cervical Dystonia Treated by Korean Medical Treatment with Yin-yang Balancing Therapy of the Temporomandibular Joint [Functional Cerebrospinal Therapy, FCST] and Miniscalpel-Acupuncture (턱관절음양균형요법과 도침치료를 병행한 한방치료를 이용한 경부 근긴장이상증 치험 1례)

  • Park, Jung Hyeon;Do, Hyun Jeong;Jung, Su Eun;Park, Song Mi;Lee, Young Jun;Kim, Cheol Hong
    • Journal of TMJ Balancing Medicine
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    • v.10 no.1
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    • pp.26-31
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    • 2020
  • Objectives: The purpose of this study is to report the effect of Korean medical treatment with FCST and Miniscalpel-Acupuncture on patient with cervical dystonia. Methods: In this study, A patient with cervical dystonia was admitted to ◯◯ Korean medicine Hospital from Oct 20th, 2020 to Nov 28th, 2020. During the admission period, the patient was treated by Korean medical treatment (acupuncture, pharmacopuncture, herb medicine, etc.), especially using FCST and Miniscalpel-Acupuncture. The Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), the Tsui score and CDIP (Cervical Dystonia Impact Profile)-58 were used for measuring the Cervical Dystonia. Results: After treatment for 40 days, the TWSTRS showed a decrease from 52.75 to 13.75, the Tsui score also decreased from 17 to 3 and the CDIP-58 score decreased from 64.1 to 25.5. Conclusions: These results showed that Korean medical treatment especially using FCST and Miniscalpel-Acupuncture may have an effect on reducing symptoms of cervical dystonia. But the further researches are needed.

Two Cases of Dystonia and Chorea in Basal Ganglia (기저핵병변(基底核病變)에 의(依)한 불수의운동(不隨意運動) 환자(患者) 2례(例)에 대(對)한 임상보고(臨床報告))

  • Kim, Gi-Yeol;Kim, Jong-Dae;Jeong, Ji-Cheon
    • Korean Journal of Oriental Medicine
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    • v.3 no.1
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    • pp.215-228
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    • 1997
  • Extrapyramidal movement disorders are divided descriptively into hypokinesias(such as parkinsonism), characterized by poverty and slowness of movement : hyperkinesias(such as chorea, athetosis, dystonia, ballism, etc.), manifested by abnormal involuntary movement. Chorea refers to widespread arrythythmic movements of a forcible, rapid, jerky, restless type Choreic movements are noted for their irregularity and variability. They are generally continuous, may be simple or quite elaborate, and affect any part of the body. Dystonla refers to abnormally increased muscular tone that causes fixed abnormal postures. Some patients with dystonia also have shifting postures, resulting from irregular, forceful twisting movement that affect trunk and produce bizarre, grotesque movements and positions of the body. The most frequent and familiar type of focal dystonia is spasmodic torticollis. It consists of an involuntary turning of the head to one side - intermittent at first, then gradually worsening to the point of being more or loss continuous. The combination of blepharospasm and oromandibular dystonia is sometimes refered to as Meige's syndrome. We report two patients with dystonia and chorea in cerebral infarction at basal ganglia. We have experienced good improvement by the oriental medicine and acupuncture treatment.'rho acupuncture points of LI 4, ST 36, TE 3, GB 34, GB 41, LR 3, GB 39 were used. The therapies of herb-medicine were treated by Zibu-Ganshen(滋補肝腎), Huoxue-Xifeng-Tongluo(活血息風通絡).

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Acute Dystonia Induced by Epidural Droperidol -A case report- (경막외강으로 Droperidol을 투여한 후 발생한 불수의 근수축 -증례 보고-)

  • Chae, Yoon-Jeong;Yoon, Kyung-Bong;Lim, Jae-Woo;Choi, Jae-Chan;Lee, Young-Bok
    • The Korean Journal of Pain
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    • v.13 no.2
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    • pp.255-258
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    • 2000
  • Epidural morphine is effective in the treatment of postoperative pain, but side effects, such as nausea, vomiting, pruritus and urinary retention commonly occur. Droperidol is frequently used as an antiemetic to prevent intraoperative and postoperative vomiting. But it has been reported to cause acute extrapyramidal effects including dystonia. We report one case of acute dystonia in young adult following the use of epidural droperidol.

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Dopa-responsive dystonia with additional unusual clinical features: A case report confirmed by molecular genetics

  • Lee, Woong-Woo;Choi, Jong-Moon;Lee, Cha Gon
    • Journal of Genetic Medicine
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    • v.17 no.1
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    • pp.34-38
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    • 2020
  • The term dopa-responsive dystonia (DRD) is used to describe a group of neurometabolic disorders, which are characterized by dystonia, and are typically associated with diurnal fluctuations and respond to levodopa treatment. Autosomal dominant DRD (DYT5a, MIM# 128230) is caused by a heterozygous mutation in the GTP cyclohydrolase 1 (GCH1) gene (MIM# 600225). GCH1 encodes an enzyme, which is involved in the biosynthesis of tetrahydrobiopterin, an essential co-factor for tyrosine hydroxylase. Herein, we report the case of a 16-year-old girl who was diagnosed with DYT5a. She exhibited additional unusual clinical features, including intellectual disability, depression, multiple skeletal anomalies, and short stature, which are not commonly observed in patients with DYT5a. The patient harbored a heterozygous missense variant, c.539A>C, p.Gln180Pro, in the GCH1 gene, which was identified by targeted gene panel analysis using next-generation sequencing.