• Title, Summary, Keyword: Epidermoid cyst

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Primary Intracranial Squamous Cell Carcinoma in the Brain Stem with a Cerebellopontine Angle Epidermoid Cyst

  • Kim, Min-Su;Kim, Oh-Lyong
    • Journal of Korean Neurosurgical Society
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    • v.44 no.6
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    • pp.401-404
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    • 2008
  • Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from a preexisting benign epidermoid cyst. We report a rare case of primary intracranial squamous cell carcinoma in the brain stem with a cerebellopontine angle (CPA) epidermoid cyst. A 72-year-old female suffered from progressive left hemiparesis, difficulty in swallowing, and right hemifacial numbness. Diffusion-weighted magnetic resonance imaging revealed a high signal intensity (SI) lesion in the CPA region and an intra-axially ring-enhanced cystic mass in the right brain stem with low SI. Whole-body positron emission tomography showed no evidence of metastatic disease. The histological findings revealed a typical epidermoid cyst in the CPA region and a squamous cell carcinoma in the brain stem. We speculate that the squamous cell carcinoma may have been developed due to a chronic inflammatory response by the adjacent epidermoid cyst. The patient underwent a surgical resection and radiotherapy. After 12 months, she had no evidence of recurrence.

Epidermoid Cyst Arising from the Corpus Callosum

  • Kim, Dok-Ryong;Kang, Hee-In;Kim, Jae-Hoon;Kim, Joo-Seung
    • Journal of Korean Neurosurgical Society
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    • v.41 no.3
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    • pp.177-179
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    • 2007
  • Most of intradural epidermoid cyst arise as slowly growing extraaxial lesions but purely intracerebral epidermoid cysts are rare. A 39-year-old female presented with a headache during several months. Brain computed tomography [CT] scan showed a mass lesion in the both frontal lobe with heterogenous density approximately $5{\times}5cm$ in size. Magnetic resonance imaging [MRI] revealed a mass of heterogenous signal intensity on T1, T2-weighted image and faint enhancement with gadolinium [Gd]. Through the both interhemispheric approach, mass was removed subtotally except the calcified portion tightly attached to the corpus callosum. The patient discharged without neurological deficit. The authors report a case of epidermoid cyst in the corpus callosum and discuss the pathogenesis of the intraparenchymal epidermoid cyst.

Malignant Transformation of an Epidermoid Cyst in the Cerebellopontine Angle

  • Chon, Kyu-Hyon;Lee, Jong-Myong;Koh, Eun-Jung;Choi, Ha-Young
    • Journal of Korean Neurosurgical Society
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    • v.52 no.2
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    • pp.148-151
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    • 2012
  • Intracranial squamous cell carcinoma is extremely rare, with most of the cases arising from malignant transformation of an epidermoid or a dermoid cyst. The patient presented with facial weakness. Initial magnetic resonance imaging revealed a mass in the right cerebellopontine angle. A subtotal resection was performed via right retrosigmoid suboccipital approach. Histopathological findings were consistent with an epidermoid tumor. Five months later, the patient underwent gamma knife radiosurgery due to highly probable recurrent epidermoid tumor. Two years after, the patient's neurological deficit had been newly developed, and follow-up magnetic resonance imaging demonstrated a large contrast-enhancing tumor in the left cerebellopontine angle, which compressed the brainstem. After resection of the tumor, histopathological examinations revealed a squamous cell carcinoma probably arising from an underlying epidermoid cyst. We report a case of an epidermoid tumor in the cerebellopontine angle that transformed into a squamous cell carcinoma.

Intradiploic Epidermoid Cyst of the Skull

  • Han, Gi-Young;Won, Yu-Sam;Yang, Jae-Young;Choi, Chun-Sik
    • Journal of Korean Neurosurgical Society
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    • v.38 no.1
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    • pp.68-70
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    • 2005
  • Intradiploic epidermoid cysts, like epidermoid cysts in other cranial locations, are rare. Approximately 100 intradiploic epidermoids have been reported, involving all of the cranial bones in proportion to their relative sizes. Over half erode through both tables of the cranium, creating variably sized areas of unprotected brain beneath the soft tumor. We report a case of an intradiploic epidermoid cyst of the right parietal bone that was found after minor head trauma.

An Intraosseous Epidermoid Cyst That Originated from the Nail Bed of Great Toe with Concurrent Joint Infection: A Case Report

  • Chung, Myung Ki;Park, Moon Seok;Kim, Yong Sung;Lee, Taeseung;Lee, Kyoung Min;Cho, Byung Chae
    • Journal of Korean Foot and Ankle Society
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    • v.20 no.1
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    • pp.50-53
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    • 2016
  • We report on a rare case of an intraosseous epidermoid cyst in the distal phalanx of the great toe with concurrent infection in a 71-year-old woman with diabetes mellitus. The lesion was initially considered simple infectious arthritis and concomitant osteomyelitis in a patient with diabetes. However, after surgery, an intraosseous epidermoid cyst originating from the nail bed and involving the articular surface of the distal phalanx was detected. The epidermoid cyst may have contributed to the infectious arthritis in the interphalangeal joint. The lesion was treated via mass excision, arthrotomy, debridement, and intravenous antibiotics.

Epidermoid cyst: A single-center review of 432 cases

  • Kim, Choon Soo;Na, Young Cheon;Yun, Chi Sun;Huh, Woo Hoe;Lim, Bo Ra
    • Archives of Craniofacial Surgery
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    • v.21 no.3
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    • pp.171-175
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    • 2020
  • Background: Epidermoid cysts are benign tumors derived from the infundibular portion of hair follicles and thus have a flattened surface epithelium and keratohyaline granules. They can occur at any age but are most frequently reported in adults, and more often occur in men than women. Most epidermoid cyst operations are performed for cosmetic purposes, or to relieve inflammation. The definitive treatment is complete excision or destruction of the cyst. The aim of this study was to improve understanding of epidermoid cysts. Methods: We analyzed 432 cases of epidermoid cyst in 398 patients that underwent complete excision and biopsy between April 2001 and March 2020, according to patient age, patient gender, and lesion location. Results: From all epidermoid cyst excisions performed, 17.6% were for patients in their 40s and 50s, 16.8% for those in their 20s, 16.1% for those in their 30s, 14.6% for those aged 60 or older, 5.0% for teenagers, and 0.5% for those under 10 years. Cases of epidermoid cysts occurred at a men-to-women ratio of about 3:2, with 59.5% of cases in men and 40.5% in women. By lesion location, 65.0% of cases were on the face, 10.9% on the trunk, 7.9% on the scalp, 7.9% on the neck, 4.3% on lower extremities, 3.9% on upper extremities, and 0.2% on genitalia. On the face, 20.8% of cases were on the cheek, 12.7% on the periauricular area, 10.9% on the periorbital area, 6.0% on the frontal area, 5.6% on the mental area, 3.7% on the perioral area, 2.8% on the nasal area, and 2.5% on the temporal area. Conclusion: The proportion of women with epidermoid cysts was higher in our study than in previous studies. Moreover, the results showed that surgery has been on the rise in recent years, with facial surgery being the most common.

Coexistence of Intracranial Squamous Cell Carcinoma and Epidermoid Cyst: a Case with Consecutive Imaging Findings

  • Lee, Chae Woon;Park, Ji Eun;Lee, Jeong Hyun;Kim, Ho Sung;Kim, Sang Joon
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.3
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    • pp.172-176
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    • 2018
  • In contrast to well-known imaging findings of intracranial epidermoid cysts on magnetic resonance imaging, those of intracranial squamous cell carcinoma (SqCC) are relatively unknown. We present a case of coexistence of intracranial SqCC and epidermoid cyst, with consecutive follow up over 14 months. Based on our case, a solid enhancing portion adjacent to a typically-looking epidermoid cyst may become a clue for coexistence of intracranial SqCC. An initial contrast enhancement and/or heterogeneous signal on diffusion weighted imaging may become a useful diagnostic clue, but more importantly, sudden rapid growth is important in formulating diagnosis.

Posttraumatic Giant Extradural Intradiploic Epidermoid Cysts of Posterior Cranial Fossa: Case Report and Review of the Literature

  • Enchev, Yavor;Kamenov, Bogidar;William, Alla;Karakostov, Vasil
    • Journal of Korean Neurosurgical Society
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    • v.49 no.1
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    • pp.53-57
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    • 2011
  • We reported a unique case of posttraumatic giant infratentorial extradural intradiploic epidermoid cyst. A 54-year-old male, with a previous history of an open scalp injury and underlying linear skull fracture in the left occipital region in childhood, presented with a painful subcutaneous swelling, which had been developed gradually in the same region and moderate headache, nausea, vomiting and cerebellar ataxia. The duration of symptoms on admission was 3 months. Imaging studies revealed occipital bone destruction and giant extradural intradiploic lesion. The preoperative diagnosis was giant infratentorial extradural intradiploic epidermoid cyst. Surgery achieved total removal of the lesion, which was histologically confirmed and the postoperative course was uneventful. To our knowledge, this is the first case of giant infratentorial extradural intradiploic epidermoid cyst with a traumatic etiology described in the literature.

Fine Needle Aspiration Cytology of Unusual Epidermoid Cyst with Diffuse Parakeratosis and Aggressive Growth - A Case Report - (미만성 이상각화증을 동반한 침습성 표피양 낭의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Nam, Hae-Joo
    • The Korean Journal of Cytopathology
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    • v.10 no.1
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    • pp.85-89
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    • 1999
  • An extremely unusual case of epidermoid cyst showing diffuse parakeratosis and aggressive clinical behavior is presented. A destructive bone lesion with surrounding ill-defined soft tissue lesion was found by computed tomography in a 63 year-old man complaining of painful swelling of the right buttock. He had a history of surgical excision twice for epidermoid cysts of soft tissue of the right hip during recent one year On aspiration cytology, the aspirate was highly cellular and mostly composed of desquamated nucleated squamous cells. Operation finding revealed that the iliac bone was Irregularly destroyed and filled with gray-white cheesy material and necrotic bone bedris. Adjacent gluteus muscle showed scattered gray-white lesions. The curettage specimen showed bone necrosis and desquamated squamous cells filling the marrow spaces. The lesion within muscle revealed epidermoid cyst with diffuse parakeratosis.

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Epidermoid Cyst of the Fourth Ventricle

  • Jeon, Ji-Young;Kim, Jae-Min;Cheong, Jin-Hwan;Kim, Choong-Hyun
    • Journal of Korean Neurosurgical Society
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    • v.38 no.6
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    • pp.478-480
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    • 2005
  • The authors describe a case of intracranial epidermoid cyst with fourth ventricle involvement. A 43-year-old woman presented with progressive aggravating headache and cerebellar syndrome due to a large tumor in the fourth ventricle, that extended into the left side of foramen of Luschka. The histopathological workup following gross total removal of tumor had revealed the typical features of an epidermoid cyst. Four months after surgery, the cerebellar sings recovered to normal with a remarkable improvement of headache. Epidermoid cysts involving the fourth ventricle have been known to be one of the most rare diseases in the central nervous system. This rare case is discussed and a review of the relevant literature is presented.