• Title, Summary, Keyword: Herb-acupuncture

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Comparative Study between Acupuncture and Acupuncture-Oriental Herb Medicine Treatment on Facial Nerve Paralysis (구안괘사에 대한 침구치료(鍼灸治療)와 침(鍼), 약(藥) 병용치료(竝用治療)의 비교 고찰)

  • Kim, Chil-Gab;Park, Sang-Dong;Kim, Kyung-Ho
    • Journal of Acupuncture Research
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    • v.18 no.3
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    • pp.10-22
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    • 2001
  • Objective : Many methods have been used for treatment of facial nerve paralysis. The purpose of this study was to evaluate the clinical difference between acupuncture therapy and acupuncture-oriental herb medicine therapy. Materials and Methods : From 05-01-2000 to 01-30-2001, 46 facial paralysis patients who were hospitalzed and treated more than five times at the Department of Acupuncture & Moxibustion of Dongguk University Bundang Oriental Medical Hospital were selected for two group. One group(A group) was treated by acupuncture therapy, the other group(B group) was treated by acupuncture and oriental herb medicine therapy. A group was composed of 15 patients and B group was 31 patients. Results and Conclusion : As the results of study, both acupuncture therapy and acupunture-oriental herb medicine therapy were usable for facial nerve paralysis treatment. But, we could not discover any available difference between acupuncture therapy group and acupuncture-oriental herb medicine therapy group.

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A Study on Effects of the Cervi Pantotricuhum Cornu Herb-acupuncture on the Osteoporosis Induced by Ovariectomy in Rats (녹용(鹿茸) 약침(藥鍼)이 난소적출(卵巢摘出)로 유발(誘發)된 백서(白鼠)의 골다공증(骨多孔症)에 미치는 영향(影響))

  • Han, Sang-Won;Lee, Yun-Ho;Kim, Chang-Hwan
    • Journal of Pharmacopuncture
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    • v.3 no.1
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    • pp.177-191
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    • 2000
  • In order to investigate the effect of the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu($BL_{23}$) and Taejo($BL_{11}$) loci on the estrogen-deficiency osteoporosis induced by ovariectomy in rats, serum osteocalcin estradiol progesterone follicular stimulating hormone(FSH) calcium(Ca) and phosphorous(P) levels were monitored. The results were as follows : 1. Serum osteocalcin levels were significantly (p<0.01, p<0.05) increased in the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu and Taejo group compared with control group. 2. Serum estradiol levels were increased In the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu and Taejo group compared with control group, but Taejo group did not show significant value. 3. Serum progesterone levels were significantly(p<0.01) increased in the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu and Taejo group compared with control group. 4. Serum FSH levels were significantly(p<0.01, p<0.05) decreased in the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu and Taejo group compared with control group. 5. Serum Ca levels were significantly(p<0.01) increased in the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu group compared with control group, but Taejo group did not show significant value. 6. Serum P levels were significantly(p<0.01, p<0.05) decreased in the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu and Taejo group compared with control group. According to these results, the Cervi Pantotricuhum Cornu Herb-acupuncture treated on Shinsu and Taejo loci have favorable effect on treatment and prevention of osteoporosis induced by ovariectomy in rats.

Analgesic effect of Clematidis Radix (CR) herb-acupuncture in a rat model of pain and inflammation

  • Hwang, Hye-Jeong;Kim, Seung-Tae;Lee, Hye-Jung;Kim, Young-Suk;Shim, In-Sop;Park, Hi-Joon;Choi, Won-Ju;Kim, Jang-Hyun;Hahm, Dae-Hyun
    • Oriental Pharmacy and Experimental Medicine
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    • v.7 no.5
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    • pp.501-508
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    • 2008
  • Anti-nociceptive and anti-inflammatory effects of Clematidis Radix (CR)-distillates were investigated in three different pain animal models. Highly purified distillate of CR was injected to Zusanli (ST36) acupoint, called CR herb-acupuncture in the Korean traditional medicine. In tail flick latency test, the CR herb-acupuncture treatment did not show a significant effect of relieving acute phasic pain. To investigate the anti-inflammatory effect of CR herb-acupuncture, inflammatory pain was induced by subcutaneous injection of formalin to the plantar tissue or intra-articular injection of carrageenan to the tibio-tarsal joint in the rats. And the medicinal effect of CR herb-acupuncture was evaluated by analyzing pain behavior such as licking or biting behavior, or by measuring weight distribution ratio between two foot and ankle circumference. In the rat formalin test, the analgesic effect of CR herb-acupuncture was more pronounced in the late phase (for 20 min after the early phase) than in the early phase (for the first 10 min post formalin injection). It also significantly alleviated the carrageenan-induced monoarthritis, in terms of weight distribution ratio and ankle edema. These results revealed that CR herb-acupuncture was effective to treat the inflammatory pain and could be used as an analgesic treatment with an antiinflammatory effect.

Effects of Puerariae radix herb-acupuncture on nitric oxide synthase expression in the hippocampus of alcohol-intoxicated Sprague-Dawley rats (갈근약침(葛根藥鍼)이 알콜 중독(中毒) 백서(白鼠) 해마(海馬)의 Nitric Oxide Synthase에 미치는 영향(影響))

  • Jung, Jae-houn;Kim, Ho-hyun;Lee, Eun-yong
    • Journal of Acupuncture Research
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    • v.20 no.4
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    • pp.1-10
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    • 2003
  • Objective: The purpose of this study was to determine the effects of Puerariae radix(PR) herb-acupuncture on nitric oxide synthase(NOS) expression in hippocampus of alcohol-intoxicated Sprague-Dawley(SD) rats. Methods: SD rats were randomly assigned into 6 groups; normal group, control group, alcohol with herb-acupuncture group(0.3, 3, 30 and 300mg/kg PR). Normal groups were received with NaCl, while alcohol intoxication groups were injected intraperitoneally with alcohol(2g/kg) twice per day for 3 days. Herb-acupuncture groups were injected on Zhongwan(CV12) for 5 consecutive days. For the detection of NADPH-d-positive cells in hippocampus, immunohistochemistry was performed. Results: n control group, a significant decrease in NADPH-d-positive cells was observed compared to normal group. In alcohol with herb-acupuncture group, NADPH-d-positive cells increased significantly compared to control group. Conclusions: The present results revealed that NOS expression is enhanced in the hippocampus of SD rats through PR herb-acupuncture in an acute alcoholic intoxication condition.

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Studies on the Safety Assessment of Red-ginseng Radix Extract Solution for Herb-acupuncture (III) (약침용 홍삼추출액의 면역독성, 발열성 및 용혈성시험에 관한 연구)

  • Nam, Yun-Seok;Lee, Yun-Ho
    • Korean Journal of Oriental Medicine
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    • v.2 no.1
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    • pp.129-145
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    • 1996
  • According to the Medical Product Safety Administration Guidelines for safety assessment guinea pigs, mice and rats were used for antigenicity test, rabbits for pyrogenic test and hymolytic test. The results were summarized as follows; 1. The antigenicity test of Red-ginseng radix extract solution for herb-acupuncture did not show any anaphylatic shock but produced IgE in high dose group. 2. The result of the pyrogen test of Red-ginseng radix extract solution for herb-acupuncture was negative. 3. The result of the hemolytic test of Red-ginseng radix extract solution for herb-acupuncture were negative in low and middle dose group but was positive in high dose group.

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Effects of Puerariae flos herb-acupuncture on cell proliferation and neurogenesis in the dentate gyrus of ethanol-induced Sprague-Dawley rats (갈화 약침이 알콜 중독 흰쥐의 치상회에서 신경세포 생성에 미치는 영향)

  • Kim Youn-Hee;Kim Ee-Hwa;Jang Mi-Hyun;Lim Back-Vin;Kim Youn-Jung;Chung Joo-Ho;Seo Jung-Chul;Kim Chang-Ju
    • Journal of Acupuncture Research
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    • v.18 no.6
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    • pp.206-214
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    • 2001
  • The purpose of this study was to determine the effects of Puerariae flos herb-acupuncture on hippocampal neural cell proliferation. Sprague-Dawley rats were randomly assigned into 4 groups; control group, control with herb-acupuncture group, alcohol group, alcohol with herb-acupuncture group group. Control groups were received with NaCl, while alcohol intoxication groups were injected intraperitoneally with alcohol (2 g/㎏) twice per day for 3 days. Herb-acupuncture groups were injected on Zhongwan (CV 12) for 5 consecutive days. Bromo-deoxyuridine (BrdU) was injected into all animal per day for 5 days. For the detection of BrdU-positive cells in dentate gyrus of hippocampus, immunohistochemistry was performed. In alcohol group, a significant decrease in BrdU-positive cells was observed compared to control group. In alcohol with herb-acupuncture group, BruU-positive cells increased significantly compared to alcohol group. In conclusion, the present results revealed that new cell proliferation is enhanced in the dentate gyros of young Sprague-Dawley rats through Puerariae flos herb-acpuncuture in an acute alcoholic intoxication condition.

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Clinical evaluation of Acupuncture and Herb-Medication on Bell's palsy by DITI (컴퓨터 적외선(赤外線) 전신체열촬영(全身體熱撮影)을 통해 살펴본 Bell' palsy에 대한 한방적 치료의 임상적(臨床的) 고찰(考察))

  • Cho, Eun-Hee;Cho, Nam-Geun;Hur, Tae-Young;Cheon, Mi-Na
    • Journal of Acupuncture Research
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    • v.17 no.2
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    • pp.19-30
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    • 2000
  • Object : This study is designed to evaluate effects of acupuncture and herb-medication by the data of DITI(Digital Infrared Thermographic Imaging) examination and the changes of clinical symptoms after the therapy of acupuncture and herb-medication in the patients with Bell's palsy. Contents : The conservative therapy with acupuncture and herb-medication was performed during 1-8weeks. The acupuncture points of S4, S6, G14, S2, BL2, SI18, TE23, LI4 and S36 was used. In the pre- and post therapy, DITI examinations were performed in patients who had Bell's palsy and were treated by acupuncture simultaneously, and then tried to correlate the results of clinical symptoms with the difference of thermographic findings at pre-and post acupuncture. Setting : The standard routine themographic examinations were performed with thermography (DITI) in the 16 patients with Bell's palsy at pre- and post acupuncture. patients : Thermographic imaging of 16cases was analyzed. They had diagnosed Bell's palsy. They were treated by acupuncture and moxibustion therapy in Wonkwang Oriental Hospital from Jauary, 1999 to February, 2000. Results : The results of treatment showes that 56.25% of patients achieved excellent recovery and 31.25% achieved good recovery. After compairing the DITI results before and after treatment, we found 43.75% of patients achieved excellent recovery and 43.75% achieved good recovery. Conclusion :Acupuncture showed good results over 87.5% in clinical evaluation and 87.5% in DITI. Thermographic examination showes terapeutic effect of acupuncture treatment.

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A Study of clinical trial method for safety of herb-acupuncture (약침제제(藥鍼製劑)의 안전성(安全性)을 위한 임상시험방법(臨床試驗方法)에 대한 연구(硏究))

  • Jun Kum-Sun;Nam Sang-Soo;Lee Jae-Dong;Choi Do-Young;Ahn Byoung-Choul;Park Dong-Seok;Lee Yun-Ho;Choi Yong-Tae
    • Journal of Acupuncture Research
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    • v.15 no.2
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    • pp.183-198
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    • 1998
  • This study was done in order to present clinical trial method for safety of herb-acupuncture. The results were summerized as follow: In case of western medicine, clinical trial divides into four phase 1. Phase I: Investigate safety and drug movement for health people. 2. The first phase II: Investigate safety, effectiveness for the limited patient. The late phase II: Investigate propriety of an applicable disease, the way to use and dose. 3. Phase III: Through the comparative, public trial, investigate a final, applicable disease and side effect. 4. Phase IV: After NDA, investigate safety and effectiveness for the wide patients. In case of herb-acupuncture, we have to investigate the following for safety and effectiveness 1. Drug dose: Decide with 1/2 or 1/3 of oral dosage or a basis of animal's of maximum dosage or a ratio of man and animal. 2. Toxicity: Examine blood, urine, liver function, EKG, after herb-acupuncture during acertain period of time. 3. Regional response: Estimate response of swelling, redness, pruritus. etc 4. Treatment effectiveness: After exactly diagnosis, estimate effectiveness with a objective guide post.

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Effects of Bee Venom Herb-Acupuncture on the Jaw Opening Reflex in Rats (흰쥐에서 합곡혈(合谷穴) 봉독약침자극(蜂毒藥針刺戟)에 의(依)한 개구반사(開口反射)의 반응(反應))

  • Kim, Ee-Hwa;Ro, Shick;Lee, Jae-Dong;Min, Byung-Il
    • The Journal of Korean Medicine
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    • v.20 no.1
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    • pp.106-112
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    • 1999
  • The purpose of this study is to investigate the effects of Bee Venom Herb-Acupuncture on the jaw opening reflex evoked by tooth pulp stimulation. Rats were anesthetized with thiopental sodium given intraperitoneally in an initial dose of 80mg/kg. Maintenance doses of 5mg/kg thiopental sodium were given through a cannular in the femoral vein as required to maintain light anesthesia. To apply noxious stimuli, a pair of enameled wires were inserted into the tooth pulp of the lower incisor. The effects of conditioning stimuli were estimated as an indicator of the degree of suppression of the digastric muscle electromyogram(dEMG) in the jaw opening reflex. Bee Venom Herb- Acupuncture(0.2% solution 0.1ml/rat) was injected to Hapgok(LI4) loci. In addition, Normal Saline (0.1ml/rat) was injected to Hapgok loci so as to compare the degree of suppression elicited from Bee-Venom. By administration of Bee Venom Herb-Acupuncture, the amplitude of dEMG was maximally suppressed to $67.5{\pm}3.38%$ ipsilaterally, 73.33{\pm}8.00%$ contralaterally. Generally, the dEMG activities caused by electrical stimulation were gradually suppressed during the stimulation and maximal suppressive effect showed at 15min after its onset. However the dEMG activities by Be Venom Herb-Acupuncture were immediately suppressed after its onset and the suppressive effect continued for a long time compared to electrical stimulation. In conclusion, Bee Venom Herb-Acupuncture may have a different mechanism of analgesia from that of electro-acupuncture and contribute to the modulation of pain analgesia.

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Three Cases of Paralytic Strabismus by Acupuncture and Herbal Medicine (마비성(痲痺性) 사시(斜視)의 한방치험(韓方治驗) 3예(例) 보고(保辜))

  • Gang, Seung-Beom;Kang, Sung-Keel;Ko, Hyung-Kyun
    • Journal of Acupuncture Research
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    • v.24 no.1
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    • pp.227-234
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    • 2007
  • Objectives : This study is to report three cases of the paralytic strabismus by acupuncture and herb medicine. Methods & Results : All patient were treated with Acupuncture and herb medicine, and the symptoms were resolved in 2 cases by above treatment during about 10 weeks. Conclusion : The cases showed proper oriental medical treatment based on the exact differentiation of symptoms had good effect on this disease as one of conservative therapies.

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